Click here to switch to the map view.

The map label for this gene is cirA [H]

Identifier: 150005607

GI number: 150005607

Start: 3912150

End: 3914453

Strand: Direct

Name: cirA [H]

Synonym: BVU_3095

Alternate gene names: 150005607

Gene position: 3912150-3914453 (Clockwise)

Preceding gene: 150005606

Following gene: 150005608

Centisome position: 75.77

GC content: 42.75

Gene sequence:

>2304_bases
ATGAAGAAATATATATTTTTCTTGATGGGAGCAGTGTGTTTTCTACTCTCATCATCGGCTGTGCACGCCAATGAATTGAA
TAAGTCCGATGCCAATATCATAGGTCATGTATTGGATAAGAATACGGAAGAGCATCTTTCTTTTATCAGCGTATCGCTGA
AAGGAACTACCATAGGAACTATGACTGACGCCAGTGGACACTATTTTCTTAAAAATCTGCCTGAAGGAGAATTTACCATG
GAGGTAAGTGCTGTCGGTTACAAGACGATCAGCCGGAAAGTAACTTTAAGAAAAGGGAAAACTTTGGAGGAGAACTTCGA
GATAGAAGAGGATTTGATAGCATTGGACGGAGTGGTGGTGTCTGCCAATCGTAGTGAGACCACCCGCCGCATGGCACCTA
CGTTGGTTAATGTGATGGATGTGAAAGTGTTTGAGAACACTAATTCCTCCACCTTGTCGCAAGGACTGAATTTTCAGCCC
GGAGTGCGGGTCGAGAATAATTGTCAGAACTGTGGTTTCCAGCAAGTACGTATCAATGGGTTGGATGGCCCTTATACGCA
GATATTGATTGACTCGCGTCCTATATTCAGTGCCTTGGCCGGTGTATATGGATTGGAACAGATACCTGCCAATATGATTG
AGCGTGTAGAGGTGATGCGCGGAGGAGGTTCGGCTTTGTTCGGTTCTTCAGCCATTGCGGGAACCATTAATATAATCACC
AAGGAGCCTGTACGGAACTCAGGGCAGTTGACACATACTCTGACAGGCATAGGCGGTACTTCTTCTTGGGATAATAATAC
GACACTGAATGCTTCGTTAGTGACTGATAATCATAAGGCAGGATTGTATATTTTTGGACAGAACAGAGAAAGAAGCGGTT
ATGACAATGATGGCGATGGCTACACCGAATTGCCAAAACTGAAAAATCAGACAGTCGGTTTTCGTTCTTTTATCAAAACA
AGTACATATTCAAAACTGACTTTTGAATATCATCATCTCAGTGAGTTCCGTCGTGGCGGGAATAAACTGAACCGACCTCC
CCATGAAGCGGATATAGCCGAACAATTGCAGCATACTATCAATAGCGGGGGAGCGAAATTTGATTATTTCTCTCCGGATG
AGAAACAGCGGCTGAGTGTATATGCTTCTGCACAGCATACAGGACGCGACAGTTATTATGGTGGAGGACAAGATGTGAAT
GCGTATGGCGCGACCACGGATTTTACCTGGGTCACAGGATCGCAGTATATCTATAGTTTTGATAAATGTTTCTTTATGCC
TGCCGATTTTACCGGAGGACTGGAATATAATCAGGATAACTTGACGGATGATATGTGGGGGTATAACCGTTATACCAAAC
AAGAAGTCCGTATAGCCAGTGCATTTTTCCAGAATGAATGGAAGAACAAGCAGTGGAGCTTTTTACTTGGAGGGCGTTTG
GATAAACATAATATGGTGGATCATGTAATCTTCAGTCCGCGTGCTAATCTTCGTTACAATCCGACCGAAAATATGAACCT
GCGTGCCAGCTATTCTTTCGGATTCCGTGCACCTCAGGCCTTTGATGAAGATTTGCATATAGAAAATGTAGGTGGGACTG
TGTCTATGATTGAACTGGCAAAAGACTTGACAGAAGAAAAATCACAAAGTCTGAGTATATCGGGAGATTTGTATCATCGT
TGGGGAGATTTTCAGGGAAACTTGCTTATAGAAGGTTTTTATACTTCGCTTTCAGACGTATTTGCCTTACGTCAGAAAGG
AGAGCGTGACGGTATTATTATCAATGAACGGTATAACGAGAAAGGAGCTAAGGTATATGGTTTGACTTTGGAAGGAAAGA
TTGCTTACCGTTCCTTACTTCAATTGCAGGCCGGCGTTACCATGCAGAAGGCCGAATACAAGCAGGCACGTGCATGGAGT
GATGATGAAACGGTTCCGATGGAGAAAAAAATGTTCCGTACTCCGAATACTTATGGATATTTCACTTTGTCATACAACCC
TTTCGTACCGATGACTATTGCATTATCCGGTACTTATACCGGTAGTATGATGGTAGAACATAAAGCAGGTTTTATTGATA
AGGACATTGCTGTGAATACACCTGATTTCTTTGAATTGAATCTGAAAGCCGGTTATGATTTCAATTTGTATAAAGGCATA
ACCATGCAGGTCAATGCTGGAGTACATAATATCTTTAATGCGTATCAAAGTGACTTTGACCGGGGGGCAAAACGTGATTC
CGGTTACATTTATGGACCGGGTATGCCGCGTTCTTACTTTGCCGGAGTGAAATTGAGTTTTTAA

Upstream 100 bases:

>100_bases
TTTTTATGTTGGTGGAGTGATTTTCCGTTACATTATCTGTTTGCGGATTCATTCTTCTGACCGCTATCCTTTTATTTATT
AATAAACAGAATAACAACAC

Downstream 100 bases:

>100_bases
TTTGTATATATTATTGCCGGGAGAGGAGCGCTGTCCGCCCTCTCCCGGCAATTTGCGTCATAGAATAAATAACCTGTTAT
AGGACTTTCGAACAGGTTAT

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 767; Mature: 767

Protein sequence:

>767_residues
MKKYIFFLMGAVCFLLSSSAVHANELNKSDANIIGHVLDKNTEEHLSFISVSLKGTTIGTMTDASGHYFLKNLPEGEFTM
EVSAVGYKTISRKVTLRKGKTLEENFEIEEDLIALDGVVVSANRSETTRRMAPTLVNVMDVKVFENTNSSTLSQGLNFQP
GVRVENNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALAGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPVRNSGQLTHTLTGIGGTSSWDNNTTLNASLVTDNHKAGLYIFGQNRERSGYDNDGDGYTELPKLKNQTVGFRSFIKT
STYSKLTFEYHHLSEFRRGGNKLNRPPHEADIAEQLQHTINSGGAKFDYFSPDEKQRLSVYASAQHTGRDSYYGGGQDVN
AYGATTDFTWVTGSQYIYSFDKCFFMPADFTGGLEYNQDNLTDDMWGYNRYTKQEVRIASAFFQNEWKNKQWSFLLGGRL
DKHNMVDHVIFSPRANLRYNPTENMNLRASYSFGFRAPQAFDEDLHIENVGGTVSMIELAKDLTEEKSQSLSISGDLYHR
WGDFQGNLLIEGFYTSLSDVFALRQKGERDGIIINERYNEKGAKVYGLTLEGKIAYRSLLQLQAGVTMQKAEYKQARAWS
DDETVPMEKKMFRTPNTYGYFTLSYNPFVPMTIALSGTYTGSMMVEHKAGFIDKDIAVNTPDFFELNLKAGYDFNLYKGI
TMQVNAGVHNIFNAYQSDFDRGAKRDSGYIYGPGMPRSYFAGVKLSF

Sequences:

>Translated_767_residues
MKKYIFFLMGAVCFLLSSSAVHANELNKSDANIIGHVLDKNTEEHLSFISVSLKGTTIGTMTDASGHYFLKNLPEGEFTM
EVSAVGYKTISRKVTLRKGKTLEENFEIEEDLIALDGVVVSANRSETTRRMAPTLVNVMDVKVFENTNSSTLSQGLNFQP
GVRVENNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALAGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPVRNSGQLTHTLTGIGGTSSWDNNTTLNASLVTDNHKAGLYIFGQNRERSGYDNDGDGYTELPKLKNQTVGFRSFIKT
STYSKLTFEYHHLSEFRRGGNKLNRPPHEADIAEQLQHTINSGGAKFDYFSPDEKQRLSVYASAQHTGRDSYYGGGQDVN
AYGATTDFTWVTGSQYIYSFDKCFFMPADFTGGLEYNQDNLTDDMWGYNRYTKQEVRIASAFFQNEWKNKQWSFLLGGRL
DKHNMVDHVIFSPRANLRYNPTENMNLRASYSFGFRAPQAFDEDLHIENVGGTVSMIELAKDLTEEKSQSLSISGDLYHR
WGDFQGNLLIEGFYTSLSDVFALRQKGERDGIIINERYNEKGAKVYGLTLEGKIAYRSLLQLQAGVTMQKAEYKQARAWS
DDETVPMEKKMFRTPNTYGYFTLSYNPFVPMTIALSGTYTGSMMVEHKAGFIDKDIAVNTPDFFELNLKAGYDFNLYKGI
TMQVNAGVHNIFNAYQSDFDRGAKRDSGYIYGPGMPRSYFAGVKLSF
>Mature_767_residues
MKKYIFFLMGAVCFLLSSSAVHANELNKSDANIIGHVLDKNTEEHLSFISVSLKGTTIGTMTDASGHYFLKNLPEGEFTM
EVSAVGYKTISRKVTLRKGKTLEENFEIEEDLIALDGVVVSANRSETTRRMAPTLVNVMDVKVFENTNSSTLSQGLNFQP
GVRVENNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALAGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
KEPVRNSGQLTHTLTGIGGTSSWDNNTTLNASLVTDNHKAGLYIFGQNRERSGYDNDGDGYTELPKLKNQTVGFRSFIKT
STYSKLTFEYHHLSEFRRGGNKLNRPPHEADIAEQLQHTINSGGAKFDYFSPDEKQRLSVYASAQHTGRDSYYGGGQDVN
AYGATTDFTWVTGSQYIYSFDKCFFMPADFTGGLEYNQDNLTDDMWGYNRYTKQEVRIASAFFQNEWKNKQWSFLLGGRL
DKHNMVDHVIFSPRANLRYNPTENMNLRASYSFGFRAPQAFDEDLHIENVGGTVSMIELAKDLTEEKSQSLSISGDLYHR
WGDFQGNLLIEGFYTSLSDVFALRQKGERDGIIINERYNEKGAKVYGLTLEGKIAYRSLLQLQAGVTMQKAEYKQARAWS
DDETVPMEKKMFRTPNTYGYFTLSYNPFVPMTIALSGTYTGSMMVEHKAGFIDKDIAVNTPDFFELNLKAGYDFNLYKGI
TMQVNAGVHNIFNAYQSDFDRGAKRDSGYIYGPGMPRSYFAGVKLSF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=616, Percent_Identity=25.1623376623377, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1790405, Length=187, Percent_Identity=29.9465240641711, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 85931; Mature: 85931

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYIFFLMGAVCFLLSSSAVHANELNKSDANIIGHVLDKNTEEHLSFISVSLKGTTIGT
CCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCHHHEEEEEEEECCCEEEE
MTDASGHYFLKNLPEGEFTMEVSAVGYKTISRKVTLRKGKTLEENFEIEEDLIALDGVVV
EECCCCCCHHHCCCCCCEEEEEEECCEEHHHEEEEECCCCCCHHCCCCHHHEEEECCEEE
SANRSETTRRMAPTLVNVMDVKVFENTNSSTLSQGLNFQPGVRVENNCQNCGFQQVRING
ECCCCHHHHHHHHHHHEEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEC
LDGPYTQILIDSRPIFSALAGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
KEPVRNSGQLTHTLTGIGGTSSWDNNTTLNASLVTDNHKAGLYIFGQNRERSGYDNDGDG
CCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCC
YTELPKLKNQTVGFRSFIKTSTYSKLTFEYHHLSEFRRGGNKLNRPPHEADIAEQLQHTI
CCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NSGGAKFDYFSPDEKQRLSVYASAQHTGRDSYYGGGQDVNAYGATTDFTWVTGSQYIYSF
HCCCCEECCCCCCCHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
DKCFFMPADFTGGLEYNQDNLTDDMWGYNRYTKQEVRIASAFFQNEWKNKQWSFLLGGRL
CEEEEECCCCCCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
DKHNMVDHVIFSPRANLRYNPTENMNLRASYSFGFRAPQAFDEDLHIENVGGTVSMIELA
CCCCCHHHEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHH
KDLTEEKSQSLSISGDLYHRWGDFQGNLLIEGFYTSLSDVFALRQKGERDGIIINERYNE
HHHHHHHHCEEEECCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCC
KGAKVYGLTLEGKIAYRSLLQLQAGVTMQKAEYKQARAWSDDETVPMEKKMFRTPNTYGY
CCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEE
FTLSYNPFVPMTIALSGTYTGSMMVEHKAGFIDKDIAVNTPDFFELNLKAGYDFNLYKGI
EEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCEEEEEEECCCCEEEECCE
TMQVNAGVHNIFNAYQSDFDRGAKRDSGYIYGPGMPRSYFAGVKLSF
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCEEEEC
>Mature Secondary Structure
MKKYIFFLMGAVCFLLSSSAVHANELNKSDANIIGHVLDKNTEEHLSFISVSLKGTTIGT
CCHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCHHHEEEEEEEECCCEEEE
MTDASGHYFLKNLPEGEFTMEVSAVGYKTISRKVTLRKGKTLEENFEIEEDLIALDGVVV
EECCCCCCHHHCCCCCCEEEEEEECCEEHHHEEEEECCCCCCHHCCCCHHHEEEECCEEE
SANRSETTRRMAPTLVNVMDVKVFENTNSSTLSQGLNFQPGVRVENNCQNCGFQQVRING
ECCCCHHHHHHHHHHHEEEEEEEEECCCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEC
LDGPYTQILIDSRPIFSALAGVYGLEQIPANMIERVEVMRGGGSALFGSSAIAGTINIIT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEEE
KEPVRNSGQLTHTLTGIGGTSSWDNNTTLNASLVTDNHKAGLYIFGQNRERSGYDNDGDG
CCCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCCCCCCCC
YTELPKLKNQTVGFRSFIKTSTYSKLTFEYHHLSEFRRGGNKLNRPPHEADIAEQLQHTI
CCCCCCCCCCCCCHHHHHHCCCCCEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
NSGGAKFDYFSPDEKQRLSVYASAQHTGRDSYYGGGQDVNAYGATTDFTWVTGSQYIYSF
HCCCCEECCCCCCCHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
DKCFFMPADFTGGLEYNQDNLTDDMWGYNRYTKQEVRIASAFFQNEWKNKQWSFLLGGRL
CEEEEECCCCCCCCEECCCCCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
DKHNMVDHVIFSPRANLRYNPTENMNLRASYSFGFRAPQAFDEDLHIENVGGTVSMIELA
CCCCCHHHEEECCCCCEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCCCCHHHHHHH
KDLTEEKSQSLSISGDLYHRWGDFQGNLLIEGFYTSLSDVFALRQKGERDGIIINERYNE
HHHHHHHHCEEEECCCEEEECCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCEEEEECCCC
KGAKVYGLTLEGKIAYRSLLQLQAGVTMQKAEYKQARAWSDDETVPMEKKMFRTPNTYGY
CCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCEE
FTLSYNPFVPMTIALSGTYTGSMMVEHKAGFIDKDIAVNTPDFFELNLKAGYDFNLYKGI
EEEEECCCCEEEEEEECCCCCCEEEEECCCCCCCCCEECCCCEEEEEEECCCCEEEECCE
TMQVNAGVHNIFNAYQSDFDRGAKRDSGYIYGPGMPRSYFAGVKLSF
EEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]