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The map label for this gene is uxaC [H]

Identifier: 150005586

GI number: 150005586

Start: 3885215

End: 3886621

Strand: Reverse

Name: uxaC [H]

Synonym: BVU_3074

Alternate gene names: 150005586

Gene position: 3886621-3885215 (Counterclockwise)

Preceding gene: 150005588

Following gene: 150005584

Centisome position: 75.28

GC content: 43.78

Gene sequence:

>1407_bases
ATGAAAAACTTTATGGATGAAAACTTCCTGCTTCAGACAGAAACTGCGCAGAAGTTGTATCATGAACATGCGGCTAAAAT
GCCTATTATCGATTACCACTGCCACCTGATTCCCCAGATGGTTGCTGATGACTATCAGTTTAAGTCACTGACAGAAATCT
GGTTGGGTGGAGACCACTATAAATGGCGTGCCATGCGTACCAACGGTGTGGACGAACGTTATTGTACCGGTAAAGACACC
ACGGACTGGGAAAAATTTGAAAAATGGGCGGAAACAGTTCCTTATACCTTCCGCAACCCATTATACCATTGGACTCATTT
GGAATTGAAAACCGCATTTGGAATCAATAAAGTATTGAATCCGAAAACTGCCCGCGAGATTTTTGATGAATGTAATGAAA
AGCTTGCCAAACCGGAATACTCCGCACGAGGCATGATGCGTCGTTATCATGTGGAAACCGTTTGTACAACCGATGATCCG
GTAGATTCATTGGAATATCACATCAAAACCCGTGAAAGCGGATTCGAAATTAAAATGCTTCCCACTTGGCGTCCGGACAA
GGCGATGGCAGTAGAAGTTCCCGCTGATTTCCGTGCTTATATGGAAAAATTGTCTGCTGTAAGCGGTGTCACGATATCTT
CTTTCGATGACATGGTGGCTGCTTTGCGGAAACGTCATGACTTCTTTGCTGAACAAGGTTGTAAATTGTCTGACCACGGA
ATTGAAGAGTTTTATGCTGAAGACTATACTGATGCTGAAATCAATGCTATATTTAATAAGGTATATGGTGGTACAGAACT
GACCAAGGAAGAAATTCTGAAATTCAAATCAGCCATGCTGATCGTATTTGGGGAAATGGATTGGGAAAAAGGATGGACCC
AGCAGTTCCACTATGGAGCAATCCGCAACAACAACACCAAGATGTTCAAACTTCTGGGACCTGATACCGGTTTCGATTCA
ATCGGTGAGTTTACCACCGCCAAAGCGATGGCTAAATTCCTTGACCGCCTGAATACAGAAGGAAAACTGACCAAAACTAT
CCTTTACAACTTGAATCCTTGCGCCAATGAAGTAATTGCCACCATGTTAGGCAACTTCCAGGATGGCACAATTCCAGGCA
AGATTCAATTCGGTTCCGGATGGTGGTTCCTCGATCAGAAAGACGGTATGGAAAAGCAGATGAATGCACTGTCATTGTTA
GGCTTGTTGAGCCGCTTCGTAGGTATGCTGACAGACTCTCGTTCATTCCTGTCTTATCCGCGTCACGAATATTTCCGCCG
TACTTTGTGCAACTTGCTGGGTAATGATGTGGAAAACGGCGAAATCCCTGCTTGCGAAATAGAACGCGTCAATCAGATGG
TGGAAGATATCTGCTATAATAATGCCAAGAAGTTCTTCCAATTCTGA

Upstream 100 bases:

>100_bases
TTAATAAATCTAAAGAGATGCTCTTTGACATCTTTTTTAGAATGAGTTTTTACTGAAAGTCAAAATAAACAACAATTATA
TAGATATAAAAAGACTACTT

Downstream 100 bases:

>100_bases
CAACCGTCAGAATGCTGAATATAAATAAATGAGGATGGAACAAATGTGTCTGCAAAAGTTTTCACTTTTTGTTCCATCCT
CATTCCAGTCATAGCAATTC

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKNFMDENFLLQTETAQKLYHEHAAKMPIIDYHCHLIPQMVADDYQFKSLTEIWLGGDHYKWRAMRTNGVDERYCTGKDT
TDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGINKVLNPKTAREIFDECNEKLAKPEYSARGMMRRYHVETVCTTDDP
VDSLEYHIKTRESGFEIKMLPTWRPDKAMAVEVPADFRAYMEKLSAVSGVTISSFDDMVAALRKRHDFFAEQGCKLSDHG
IEEFYAEDYTDAEINAIFNKVYGGTELTKEEILKFKSAMLIVFGEMDWEKGWTQQFHYGAIRNNNTKMFKLLGPDTGFDS
IGEFTTAKAMAKFLDRLNTEGKLTKTILYNLNPCANEVIATMLGNFQDGTIPGKIQFGSGWWFLDQKDGMEKQMNALSLL
GLLSRFVGMLTDSRSFLSYPRHEYFRRTLCNLLGNDVENGEIPACEIERVNQMVEDICYNNAKKFFQF

Sequences:

>Translated_468_residues
MKNFMDENFLLQTETAQKLYHEHAAKMPIIDYHCHLIPQMVADDYQFKSLTEIWLGGDHYKWRAMRTNGVDERYCTGKDT
TDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGINKVLNPKTAREIFDECNEKLAKPEYSARGMMRRYHVETVCTTDDP
VDSLEYHIKTRESGFEIKMLPTWRPDKAMAVEVPADFRAYMEKLSAVSGVTISSFDDMVAALRKRHDFFAEQGCKLSDHG
IEEFYAEDYTDAEINAIFNKVYGGTELTKEEILKFKSAMLIVFGEMDWEKGWTQQFHYGAIRNNNTKMFKLLGPDTGFDS
IGEFTTAKAMAKFLDRLNTEGKLTKTILYNLNPCANEVIATMLGNFQDGTIPGKIQFGSGWWFLDQKDGMEKQMNALSLL
GLLSRFVGMLTDSRSFLSYPRHEYFRRTLCNLLGNDVENGEIPACEIERVNQMVEDICYNNAKKFFQF
>Mature_468_residues
MKNFMDENFLLQTETAQKLYHEHAAKMPIIDYHCHLIPQMVADDYQFKSLTEIWLGGDHYKWRAMRTNGVDERYCTGKDT
TDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGINKVLNPKTAREIFDECNEKLAKPEYSARGMMRRYHVETVCTTDDP
VDSLEYHIKTRESGFEIKMLPTWRPDKAMAVEVPADFRAYMEKLSAVSGVTISSFDDMVAALRKRHDFFAEQGCKLSDHG
IEEFYAEDYTDAEINAIFNKVYGGTELTKEEILKFKSAMLIVFGEMDWEKGWTQQFHYGAIRNNNTKMFKLLGPDTGFDS
IGEFTTAKAMAKFLDRLNTEGKLTKTILYNLNPCANEVIATMLGNFQDGTIPGKIQFGSGWWFLDQKDGMEKQMNALSLL
GLLSRFVGMLTDSRSFLSYPRHEYFRRTLCNLLGNDVENGEIPACEIERVNQMVEDICYNNAKKFFQF

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=468, Percent_Identity=57.0512820512821, Blast_Score=550, Evalue=1e-158,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 54307; Mature: 54307

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNFMDENFLLQTETAQKLYHEHAAKMPIIDYHCHLIPQMVADDYQFKSLTEIWLGGDHY
CCCCCCCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
KWRAMRTNGVDERYCTGKDTTDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGINKVLN
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCEEEEEEEHHHHCHHHHCC
PKTAREIFDECNEKLAKPEYSARGMMRRYHVETVCTTDDPVDSLEYHIKTRESGFEIKML
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCHHHHHEEEEECCCCCEEEEC
PTWRPDKAMAVEVPADFRAYMEKLSAVSGVTISSFDDMVAALRKRHDFFAEQGCKLSDHG
CCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEEFYAEDYTDAEINAIFNKVYGGTELTKEEILKFKSAMLIVFGEMDWEKGWTQQFHYGA
HHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCCHHHCCCE
IRNNNTKMFKLLGPDTGFDSIGEFTTAKAMAKFLDRLNTEGKLTKTILYNLNPCANEVIA
EECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCHHHHHHHH
TMLGNFQDGTIPGKIQFGSGWWFLDQKDGMEKQMNALSLLGLLSRFVGMLTDSRSFLSYP
HHHCCCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
RHEYFRRTLCNLLGNDVENGEIPACEIERVNQMVEDICYNNAKKFFQF
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCC
>Mature Secondary Structure
MKNFMDENFLLQTETAQKLYHEHAAKMPIIDYHCHLIPQMVADDYQFKSLTEIWLGGDHY
CCCCCCCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
KWRAMRTNGVDERYCTGKDTTDWEKFEKWAETVPYTFRNPLYHWTHLELKTAFGINKVLN
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHCCCCCEEEEEEEHHHHCHHHHCC
PKTAREIFDECNEKLAKPEYSARGMMRRYHVETVCTTDDPVDSLEYHIKTRESGFEIKML
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEECCCCCHHHHHEEEEECCCCCEEEEC
PTWRPDKAMAVEVPADFRAYMEKLSAVSGVTISSFDDMVAALRKRHDFFAEQGCKLSDHG
CCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
IEEFYAEDYTDAEINAIFNKVYGGTELTKEEILKFKSAMLIVFGEMDWEKGWTQQFHYGA
HHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCEEEEEECCCCCCCCCHHHCCCE
IRNNNTKMFKLLGPDTGFDSIGEFTTAKAMAKFLDRLNTEGKLTKTILYNLNPCANEVIA
EECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHEEECCCHHHHHHHH
TMLGNFQDGTIPGKIQFGSGWWFLDQKDGMEKQMNALSLLGLLSRFVGMLTDSRSFLSYP
HHHCCCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCC
RHEYFRRTLCNLLGNDVENGEIPACEIERVNQMVEDICYNNAKKFFQF
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]