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The map label for this gene is ileS [H]

Identifier: 150005574

GI number: 150005574

Start: 3870549

End: 3874037

Strand: Direct

Name: ileS [H]

Synonym: BVU_3059

Alternate gene names: 150005574

Gene position: 3870549-3874037 (Clockwise)

Preceding gene: 150005573

Following gene: 150005575

Centisome position: 74.96

GC content: 46.83

Gene sequence:

>3489_bases
ATGAGTAAGAAATTTGCTGAACACTCGCAACTCAACCTATCACAGGTCAATAAAGATGTGCTGAAGAAGTGGGATGAAAA
CGATGTTTTCGCCAAGAGTATGACAGAACGTGAAGGATGTCCTTCTTTCGTGTTTTATGAAGGACCTCCCTCGGCCAATG
GTATGCCGGGTATTCACCACGTGATGGCGCGTACCATTAAAGATACTTTCTGCCGCTATAAAACCATGAAAGGGTTCCAG
GTAAAGCGTAAGGCCGGATGGGATACTCACGGACTGCCTGTGGAACTGGGTGTGGAAAAGGCATTGCATATCACCAAAGA
GGATATCGGAAAGACCATTTCTGTTGCCGAGTACAACGCAGCTTGCCGTAAGGACGTGATGAAGTTTACCAAAGAGTGGA
CAGACCTTACTCATAAGATGGGTTACTGGGTGGATTTGGAGAATCCCTATATCACTTATGACAACCGCTATATTGAAACG
CTGTGGTGGCTCTTGAAGCAGCTTTATAACAAAGGTCTGTTATATAAAGGCTACACCATCCAGCCTTACTCTCCGGCTGC
CGGAACAGGATTGAGCTCGCACGAGCTGAACCAGCCGGGCTGTTACCGTGATGTGAAAGACACCACTGTGGTAGGACAGT
TCAAGATGAAGAATCCGAAACCCGAAATGGCGGAATGGGGAACGCCTTATTTCCTGGCATGGACCACTACTCCGTGGACA
TTGCCTTCGAATACGGCATTGTGCGTAGGACCGAAAATAGACTATGTGGCTGTGCAGACTTACAACGGATATACCGGGGA
AAAGATGACCGTAGTGTTGGCGAAAGCTTTGCTCTATACTCACTTTAACAAGAAAGCGGAAGAATTGGCGCTGGAAGACT
ATAAGCCGGGTGACAAACTGATTCCGTTCAAAGTAGTGGGTGAATATAAAGGACCGGATCTGGTAGGCATGGAATATGAA
CAGCTTATTCCTTGGGTGAAACCGGTGACAGTGGATGAAAACGGGAAATGGCAAGAAGCGGCCGGTGAGGCATTCCGCGT
TATTCCCGGTGACTATGTAACTACCGAAGATGGTACGGGTATCGTACATATCGCTCCGACATTCGGTGCAGACGATGCTT
TTGTGGCACGTGCGGCAGGTATTCCTTCTCTGTTCATGATAAACAAGAAGGGGGAAACCCGTCCTATGGTGGATCTGACT
GGTAAATTCTATCTGTTGGACGAACTGGACGAGGCTTTCGTAAAGGAATGTGTGGACGTAGAGAAATATAAGGAATATCA
GGGCCGGTGGGTGAAGAATGCTTATGATCCTCAGTTTACTGTAGATGGCAAGTACGATGAAAAAGCTGCCGCTGCCGCCG
AATCACTCGATATCTATATCTGTATGATGATGAAAGCCGCCAACAAGGCGTTCAAGATAGAAAAGCATGTACACAATTAT
CCGCACTGCTGGCGTACTGACAAACCGGTGCTCTACTATCCGCTGGACAGTTGGTTCATCCGGTCTACCGCAGCCAAAGA
GCGCATGATGGAACTGAACAAGACTATCAACTGGAAGCCGGAATCTACCGGAACAGGCCGTTTCGGCAAGTGGCTGGAAA
ACTTGAATGACTGGAACTTGAGCCGTTCTCGTTATTGGGGAACTCCGCTGCCTATCTGGCGCAGTGAAGAAGGAGAGGAG
CTTTGTATCGGTTCCGTAGAGGAATTGTATGATGAAATAGAAAAATCAATAGCTGCCGGATTTATGACCGTCAATCCTTA
TAAGGAAAAAGGTTTTGTTCCGGGCGAATATAACGGGGAGAATTATGACAAGATAGACCTTCACCGTCCGTATGTGGATG
ATATCATCTTGGTATCTGAAAGCGGCAAGCCGATGAAACGTGAGGCGGACTTGATTGATGTGTGGTTCGACTCCGGTGCG
ATGCCTTACGCGCAGTTGCACTATCCGTTCGAAAATAAGGAAATTGTGGACAACCGCACTTATTATCCTGCGGACTTCAT
TGCAGAAGGGGTGGACCAGACCCGTGGCTGGTTCTTTACGTTACATGCTATCGCTACGATGGTATTCGACAGTGTGGCTT
ACAAGAACGTAATCTCTAACGGCTTGGTTCTGGACAAGAACGGAAACAAAATGTCAAAACGTCTGGGCAATGCGGTAGAT
CCGTTCGGCGCTATCGAACAGTATGGCTCCGATCCTTTGCGTTGGTACATGATTACCAATTCTTCTCCGTGGGATAACTT
GAAATTTGATACCGACGGGGTGGATGAGGTTCGTCGTAAATTCTTCGGTACTTTGTATAATACCTATTCGTTCTTCGCAC
TTTATGCCAATGTGGATGGCTTCGCTTATCAGGAAGCGGAAGTGCCGGTAAATGAACGTCCGGAGATAGACCGTTGGATT
CTGTCTGTTCTGAATTCATTGGTGAAGAACGTGGACGCTTGCTACAACGATTACGAACCGACCAAGGCGGGACGTTTGAT
TACAGACTTCGTAAATGATAATTTGAGTAACTGGTACGTGCGCTTGAACCGTAAACGTTTCTGGGGTAATGCCATGTCAC
AGGATAAGCTGTCCGCTTATCAGACATTGTATACTTGTCTTGAAACAGTGGCCAGGCTGATGGCGCCCATCGCTCCGTTC
TATGCCGACCGGTTGTATACGGATTTGATTGCGGCTACAGGTCGTGACACCGTGGCTTCTGTACACTTGGCCAAGTTCCC
GGAATGTAATGAGGCATTGATAGACGGAGAACTGGAAGCGCGTATGCAGATGGCTCAGGATGTTACTTCTATGGTATTGG
CATTGCGCCGCAAAGTCAATATCAAAGTGCGCCAGCCTTTGCAGTGTATCATGGTTCCGGTGGTGGACGAAGAGCAGAAA
ATGCACATCGAAGCCGTAAAAGACTTGATTATGAGCGAAGTGAACGTGAAAGAAATCAAGTTTGTAGACGGAGCCGCAGG
CGTATTGGTGAAAAAGGTGAAATGTGACTTTAAAAAACTCGGCCCGAAATTCGGCAAACAGATGAAAGCTGTCGCCGCAG
CCGTAGCCGGAATGTCGCAGGAAGCTATTGCCGAATTGGAGAAAAATGGTAAATATACCTTTGTGCTTGATGGTGCGGAA
GCGGTTATCGAAACAACGGATGTGGAGATTTTCAGTGAGGATATTCCGGGATGGCTGGTTGCCAATGAAGGTAAACTGAC
TGTGGCCTTGGAGGTTACCGTAACCGAAGAACTGCGTCGTGAGGGGGTTGCCCGTGAATTGGTAAACCGTATACAGAATA
TCCGTAAGAGCAGTGGTTTTGAGATAACGGACAAAATAAAAGTGGCATTATCTAAAAATCCTCAAACCGATGATGCGGTA
AATGAATATAATACTTATATTTGTAACCAGGTTCTTGCTAACTCCCTGGAATTAGTGGATGAAGTGAAGAACGGTACAGA
ATTAAATTTTGATGATTTCTCACTTTATGTGAGTGTCGTAAAAGAATAA

Upstream 100 bases:

>100_bases
TCAAAACTTTCTATCTATCTAATTTTCTTGTAAATTTGCACCTTAATTTTTGGAAGGCATTGCCTTTTAGTTAGAGAATA
CAAGAAAACGATATAAAATT

Downstream 100 bases:

>100_bases
TTAACCTTTTAAAACTAAGTTATATGGCTGAAAAAACTAGATATTCAGATGCGGAACTGGAGGAATTCCGTGCCATTATC
ATGGAAAAACTGGAATTGGC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS [H]

Number of amino acids: Translated: 1162; Mature: 1161

Protein sequence:

>1162_residues
MSKKFAEHSQLNLSQVNKDVLKKWDENDVFAKSMTEREGCPSFVFYEGPPSANGMPGIHHVMARTIKDTFCRYKTMKGFQ
VKRKAGWDTHGLPVELGVEKALHITKEDIGKTISVAEYNAACRKDVMKFTKEWTDLTHKMGYWVDLENPYITYDNRYIET
LWWLLKQLYNKGLLYKGYTIQPYSPAAGTGLSSHELNQPGCYRDVKDTTVVGQFKMKNPKPEMAEWGTPYFLAWTTTPWT
LPSNTALCVGPKIDYVAVQTYNGYTGEKMTVVLAKALLYTHFNKKAEELALEDYKPGDKLIPFKVVGEYKGPDLVGMEYE
QLIPWVKPVTVDENGKWQEAAGEAFRVIPGDYVTTEDGTGIVHIAPTFGADDAFVARAAGIPSLFMINKKGETRPMVDLT
GKFYLLDELDEAFVKECVDVEKYKEYQGRWVKNAYDPQFTVDGKYDEKAAAAAESLDIYICMMMKAANKAFKIEKHVHNY
PHCWRTDKPVLYYPLDSWFIRSTAAKERMMELNKTINWKPESTGTGRFGKWLENLNDWNLSRSRYWGTPLPIWRSEEGEE
LCIGSVEELYDEIEKSIAAGFMTVNPYKEKGFVPGEYNGENYDKIDLHRPYVDDIILVSESGKPMKREADLIDVWFDSGA
MPYAQLHYPFENKEIVDNRTYYPADFIAEGVDQTRGWFFTLHAIATMVFDSVAYKNVISNGLVLDKNGNKMSKRLGNAVD
PFGAIEQYGSDPLRWYMITNSSPWDNLKFDTDGVDEVRRKFFGTLYNTYSFFALYANVDGFAYQEAEVPVNERPEIDRWI
LSVLNSLVKNVDACYNDYEPTKAGRLITDFVNDNLSNWYVRLNRKRFWGNAMSQDKLSAYQTLYTCLETVARLMAPIAPF
YADRLYTDLIAATGRDTVASVHLAKFPECNEALIDGELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMVPVVDEEQK
MHIEAVKDLIMSEVNVKEIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAGMSQEAIAELEKNGKYTFVLDGAE
AVIETTDVEIFSEDIPGWLVANEGKLTVALEVTVTEELRREGVARELVNRIQNIRKSSGFEITDKIKVALSKNPQTDDAV
NEYNTYICNQVLANSLELVDEVKNGTELNFDDFSLYVSVVKE

Sequences:

>Translated_1162_residues
MSKKFAEHSQLNLSQVNKDVLKKWDENDVFAKSMTEREGCPSFVFYEGPPSANGMPGIHHVMARTIKDTFCRYKTMKGFQ
VKRKAGWDTHGLPVELGVEKALHITKEDIGKTISVAEYNAACRKDVMKFTKEWTDLTHKMGYWVDLENPYITYDNRYIET
LWWLLKQLYNKGLLYKGYTIQPYSPAAGTGLSSHELNQPGCYRDVKDTTVVGQFKMKNPKPEMAEWGTPYFLAWTTTPWT
LPSNTALCVGPKIDYVAVQTYNGYTGEKMTVVLAKALLYTHFNKKAEELALEDYKPGDKLIPFKVVGEYKGPDLVGMEYE
QLIPWVKPVTVDENGKWQEAAGEAFRVIPGDYVTTEDGTGIVHIAPTFGADDAFVARAAGIPSLFMINKKGETRPMVDLT
GKFYLLDELDEAFVKECVDVEKYKEYQGRWVKNAYDPQFTVDGKYDEKAAAAAESLDIYICMMMKAANKAFKIEKHVHNY
PHCWRTDKPVLYYPLDSWFIRSTAAKERMMELNKTINWKPESTGTGRFGKWLENLNDWNLSRSRYWGTPLPIWRSEEGEE
LCIGSVEELYDEIEKSIAAGFMTVNPYKEKGFVPGEYNGENYDKIDLHRPYVDDIILVSESGKPMKREADLIDVWFDSGA
MPYAQLHYPFENKEIVDNRTYYPADFIAEGVDQTRGWFFTLHAIATMVFDSVAYKNVISNGLVLDKNGNKMSKRLGNAVD
PFGAIEQYGSDPLRWYMITNSSPWDNLKFDTDGVDEVRRKFFGTLYNTYSFFALYANVDGFAYQEAEVPVNERPEIDRWI
LSVLNSLVKNVDACYNDYEPTKAGRLITDFVNDNLSNWYVRLNRKRFWGNAMSQDKLSAYQTLYTCLETVARLMAPIAPF
YADRLYTDLIAATGRDTVASVHLAKFPECNEALIDGELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMVPVVDEEQK
MHIEAVKDLIMSEVNVKEIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAGMSQEAIAELEKNGKYTFVLDGAE
AVIETTDVEIFSEDIPGWLVANEGKLTVALEVTVTEELRREGVARELVNRIQNIRKSSGFEITDKIKVALSKNPQTDDAV
NEYNTYICNQVLANSLELVDEVKNGTELNFDDFSLYVSVVKE
>Mature_1161_residues
SKKFAEHSQLNLSQVNKDVLKKWDENDVFAKSMTEREGCPSFVFYEGPPSANGMPGIHHVMARTIKDTFCRYKTMKGFQV
KRKAGWDTHGLPVELGVEKALHITKEDIGKTISVAEYNAACRKDVMKFTKEWTDLTHKMGYWVDLENPYITYDNRYIETL
WWLLKQLYNKGLLYKGYTIQPYSPAAGTGLSSHELNQPGCYRDVKDTTVVGQFKMKNPKPEMAEWGTPYFLAWTTTPWTL
PSNTALCVGPKIDYVAVQTYNGYTGEKMTVVLAKALLYTHFNKKAEELALEDYKPGDKLIPFKVVGEYKGPDLVGMEYEQ
LIPWVKPVTVDENGKWQEAAGEAFRVIPGDYVTTEDGTGIVHIAPTFGADDAFVARAAGIPSLFMINKKGETRPMVDLTG
KFYLLDELDEAFVKECVDVEKYKEYQGRWVKNAYDPQFTVDGKYDEKAAAAAESLDIYICMMMKAANKAFKIEKHVHNYP
HCWRTDKPVLYYPLDSWFIRSTAAKERMMELNKTINWKPESTGTGRFGKWLENLNDWNLSRSRYWGTPLPIWRSEEGEEL
CIGSVEELYDEIEKSIAAGFMTVNPYKEKGFVPGEYNGENYDKIDLHRPYVDDIILVSESGKPMKREADLIDVWFDSGAM
PYAQLHYPFENKEIVDNRTYYPADFIAEGVDQTRGWFFTLHAIATMVFDSVAYKNVISNGLVLDKNGNKMSKRLGNAVDP
FGAIEQYGSDPLRWYMITNSSPWDNLKFDTDGVDEVRRKFFGTLYNTYSFFALYANVDGFAYQEAEVPVNERPEIDRWIL
SVLNSLVKNVDACYNDYEPTKAGRLITDFVNDNLSNWYVRLNRKRFWGNAMSQDKLSAYQTLYTCLETVARLMAPIAPFY
ADRLYTDLIAATGRDTVASVHLAKFPECNEALIDGELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMVPVVDEEQKM
HIEAVKDLIMSEVNVKEIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAGMSQEAIAELEKNGKYTFVLDGAEA
VIETTDVEIFSEDIPGWLVANEGKLTVALEVTVTEELRREGVARELVNRIQNIRKSSGFEITDKIKVALSKNPQTDDAVN
EYNTYICNQVLANSLELVDEVKNGTELNFDDFSLYVSVVKE

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI94721239, Length=1155, Percent_Identity=34.1125541125541, Blast_Score=615, Evalue=1e-176,
Organism=Homo sapiens, GI94721241, Length=1155, Percent_Identity=34.1125541125541, Blast_Score=615, Evalue=1e-176,
Organism=Homo sapiens, GI46852147, Length=879, Percent_Identity=27.4175199089875, Blast_Score=270, Evalue=8e-72,
Organism=Homo sapiens, GI268370295, Length=527, Percent_Identity=22.9601518026565, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI268370297, Length=527, Percent_Identity=22.9601518026565, Blast_Score=120, Evalue=1e-26,
Organism=Homo sapiens, GI268370293, Length=527, Percent_Identity=22.9601518026565, Blast_Score=119, Evalue=1e-26,
Organism=Escherichia coli, GI2367096, Length=893, Percent_Identity=25.1959686450168, Blast_Score=263, Evalue=4e-71,
Organism=Escherichia coli, GI1790708, Length=601, Percent_Identity=21.4642262895175, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17541896, Length=1127, Percent_Identity=33.3629103815439, Blast_Score=580, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI71980946, Length=885, Percent_Identity=26.2146892655367, Blast_Score=248, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17510661, Length=531, Percent_Identity=22.2222222222222, Blast_Score=106, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1137, Percent_Identity=33.509234828496, Blast_Score=594, Evalue=1e-170,
Organism=Saccharomyces cerevisiae, GI6325217, Length=870, Percent_Identity=25.9770114942529, Blast_Score=215, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321531, Length=456, Percent_Identity=23.6842105263158, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28574730, Length=1126, Percent_Identity=33.4813499111901, Blast_Score=603, Evalue=1e-172,
Organism=Drosophila melanogaster, GI24668547, Length=1126, Percent_Identity=33.4813499111901, Blast_Score=603, Evalue=1e-172,
Organism=Drosophila melanogaster, GI24668543, Length=1126, Percent_Identity=33.4813499111901, Blast_Score=603, Evalue=1e-172,
Organism=Drosophila melanogaster, GI281366294, Length=857, Percent_Identity=24.3873978996499, Blast_Score=229, Evalue=8e-60,
Organism=Drosophila melanogaster, GI17864482, Length=638, Percent_Identity=21.6300940438871, Blast_Score=109, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24653289, Length=638, Percent_Identity=21.6300940438871, Blast_Score=109, Evalue=1e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008 [H]

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]

EC number: =6.1.1.5 [H]

Molecular weight: Translated: 132172; Mature: 132041

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKFAEHSQLNLSQVNKDVLKKWDENDVFAKSMTEREGCPSFVFYEGPPSANGMPGIHH
CCCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHH
VMARTIKDTFCRYKTMKGFQVKRKAGWDTHGLPVELGVEKALHITKEDIGKTISVAEYNA
HHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCEEECHHHHHHHHHHHHCCEEEEHHHHH
ACRKDVMKFTKEWTDLTHKMGYWVDLENPYITYDNRYIETLWWLLKQLYNKGLLYKGYTI
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCEECCEEE
QPYSPAAGTGLSSHELNQPGCYRDVKDTTVVGQFKMKNPKPEMAEWGTPYFLAWTTTPWT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEEEEEECCCCC
LPSNTALCVGPKIDYVAVQTYNGYTGEKMTVVLAKALLYTHFNKKAEELALEDYKPGDKL
CCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
IPFKVVGEYKGPDLVGMEYEQLIPWVKPVTVDENGKWQEAAGEAFRVIPGDYVTTEDGTG
CEEEEEECCCCCCEECCCHHHHCCCCCCEEECCCCCHHHHCCCEEEECCCCEEECCCCCE
IVHIAPTFGADDAFVARAAGIPSLFMINKKGETRPMVDLTGKFYLLDELDEAFVKECVDV
EEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCEEEECCCEEEHHHHHHHHHHHHHHH
EKYKEYQGRWVKNAYDPQFTVDGKYDEKAAAAAESLDIYICMMMKAANKAFKIEKHVHNY
HHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHCCC
PHCWRTDKPVLYYPLDSWFIRSTAAKERMMELNKTINWKPESTGTGRFGKWLENLNDWNL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCC
SRSRYWGTPLPIWRSEEGEELCIGSVEELYDEIEKSIAAGFMTVNPYKEKGFVPGEYNGE
CCCCCCCCCCCCCCCCCCCEEHHCCHHHHHHHHHHHHHHCEEEECCHHHCCCCCCCCCCC
NYDKIDLHRPYVDDIILVSESGKPMKREADLIDVWFDSGAMPYAQLHYPFENKEIVDNRT
CCCEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHEEECCCCCCEECCCCC
YYPADFIAEGVDQTRGWFFTLHAIATMVFDSVAYKNVISNGLVLDKNGNKMSKRLGNAVD
CCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCC
PFGAIEQYGSDPLRWYMITNSSPWDNLKFDTDGVDEVRRKFFGTLYNTYSFFALYANVDG
CCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCC
FAYQEAEVPVNERPEIDRWILSVLNSLVKNVDACYNDYEPTKAGRLITDFVNDNLSNWYV
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEE
RLNRKRFWGNAMSQDKLSAYQTLYTCLETVARLMAPIAPFYADRLYTDLIAATGRDTVAS
EEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
VHLAKFPECNEALIDGELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMVPVVDEEQK
EHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCHHH
MHIEAVKDLIMSEVNVKEIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAGMSQ
HHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
EAIAELEKNGKYTFVLDGAEAVIETTDVEIFSEDIPGWLVANEGKLTVALEVTVTEELRR
HHHHHHHHCCCEEEEECCCCCEEEECCCEEECCCCCCEEEECCCEEEEEEEEEEHHHHHH
EGVARELVNRIQNIRKSSGFEITDKIKVALSKNPQTDDAVNEYNTYICNQVLANSLELVD
CCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EVKNGTELNFDDFSLYVSVVKE
HHCCCCCCCCCHHHHHEEECCC
>Mature Secondary Structure 
SKKFAEHSQLNLSQVNKDVLKKWDENDVFAKSMTEREGCPSFVFYEGPPSANGMPGIHH
CCCCCCHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHH
VMARTIKDTFCRYKTMKGFQVKRKAGWDTHGLPVELGVEKALHITKEDIGKTISVAEYNA
HHHHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCEEECHHHHHHHHHHHHCCEEEEHHHHH
ACRKDVMKFTKEWTDLTHKMGYWVDLENPYITYDNRYIETLWWLLKQLYNKGLLYKGYTI
HHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEECCHHHHHHHHHHHHHHCCCCEECCEEE
QPYSPAAGTGLSSHELNQPGCYRDVKDTTVVGQFKMKNPKPEMAEWGTPYFLAWTTTPWT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHCCCCEEEEEECCCCC
LPSNTALCVGPKIDYVAVQTYNGYTGEKMTVVLAKALLYTHFNKKAEELALEDYKPGDKL
CCCCCEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCC
IPFKVVGEYKGPDLVGMEYEQLIPWVKPVTVDENGKWQEAAGEAFRVIPGDYVTTEDGTG
CEEEEEECCCCCCEECCCHHHHCCCCCCEEECCCCCHHHHCCCEEEECCCCEEECCCCCE
IVHIAPTFGADDAFVARAAGIPSLFMINKKGETRPMVDLTGKFYLLDELDEAFVKECVDV
EEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCEEEECCCEEEHHHHHHHHHHHHHHH
EKYKEYQGRWVKNAYDPQFTVDGKYDEKAAAAAESLDIYICMMMKAANKAFKIEKHVHNY
HHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHEEHHHHHCCHHHHHHHHHCCC
PHCWRTDKPVLYYPLDSWFIRSTAAKERMMELNKTINWKPESTGTGRFGKWLENLNDWNL
CCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCC
SRSRYWGTPLPIWRSEEGEELCIGSVEELYDEIEKSIAAGFMTVNPYKEKGFVPGEYNGE
CCCCCCCCCCCCCCCCCCCEEHHCCHHHHHHHHHHHHHHCEEEECCHHHCCCCCCCCCCC
NYDKIDLHRPYVDDIILVSESGKPMKREADLIDVWFDSGAMPYAQLHYPFENKEIVDNRT
CCCEEECCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHEEECCCCCCEECCCCC
YYPADFIAEGVDQTRGWFFTLHAIATMVFDSVAYKNVISNGLVLDKNGNKMSKRLGNAVD
CCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHCCCCCC
PFGAIEQYGSDPLRWYMITNSSPWDNLKFDTDGVDEVRRKFFGTLYNTYSFFALYANVDG
CCHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEECCCC
FAYQEAEVPVNERPEIDRWILSVLNSLVKNVDACYNDYEPTKAGRLITDFVNDNLSNWYV
CEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCEEEE
RLNRKRFWGNAMSQDKLSAYQTLYTCLETVARLMAPIAPFYADRLYTDLIAATGRDTVAS
EEECHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHE
VHLAKFPECNEALIDGELEARMQMAQDVTSMVLALRRKVNIKVRQPLQCIMVPVVDEEQK
EHHHCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEEECCCHHH
MHIEAVKDLIMSEVNVKEIKFVDGAAGVLVKKVKCDFKKLGPKFGKQMKAVAAAVAGMSQ
HHHHHHHHHHHCCCCHHHEEEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
EAIAELEKNGKYTFVLDGAEAVIETTDVEIFSEDIPGWLVANEGKLTVALEVTVTEELRR
HHHHHHHHCCCEEEEECCCCCEEEECCCEEECCCCCCEEEECCCEEEEEEEEEEHHHHHH
EGVARELVNRIQNIRKSSGFEITDKIKVALSKNPQTDDAVNEYNTYICNQVLANSLELVD
CCHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EVKNGTELNFDDFSLYVSVVKE
HHCCCCCCCCCHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12663928 [H]