Click here to switch to the map view.

The map label for this gene is uxaA [H]

Identifier: 150005568

GI number: 150005568

Start: 3863301

End: 3864791

Strand: Reverse

Name: uxaA [H]

Synonym: BVU_3053

Alternate gene names: 150005568

Gene position: 3864791-3863301 (Counterclockwise)

Preceding gene: 150005569

Following gene: 150005567

Centisome position: 74.85

GC content: 51.11

Gene sequence:

>1491_bases
ATGGAAACAAAGTATTTGAAAATCAATCCGGCTGATAACGTAGTGGTGGCTATCTCGGATTTAAAAGCAGGCGAGGCCAT
CACGGTAGACGGTCATGCCATCACGTTGAAGGAAGACGTGCCTGCCGGCCATAAGGTGACACTGAAAGATTTCGCCCAAG
GCGAGAATATCATCAAGTATGGTTACCCCATCGGCCATGCCGTGACTGCCGTGGAACAAGGACGCTGGATCAATGAAACC
CAGATAAAGACAAACCTTGCCGGACTGTTGGATTACACCTACAATCCGGTCAGCGTAGACCTCAATATCCCGAAGAAAGA
CCTGACGTTCAAAGGATACCGCCGCAAAAACGGTGATGTAGGTATCCGTAACGAGGTATGGATTATCCCCACCGTGGGTT
GTGTAAACGGTATCATCGGACAACTGGCCGAAGCGTTACGCCGCGAAACCAACTGCGAAGGTGTGGACGCTATCGTGGCA
TTCCCTCACAACTATGGCTGTTCACAGCTGGGCGATGACCACGAGAATACCAAGAAAATTCTCCGCGACATGATTCTGCA
TCCTAATGCAGGAGCCGTACTGATTGTCAGTCTGGGCTGCGAGAACAACCAGCCGGATGTTTTCCGCGAGTTTCTGGGCG
ATTACGACACAGACCGCGTAAAGTTCATGGTAACCCAGAAAGTGGGGGATGAATTTGAAGAGGGTATGAAGATTCTGCGT
GAACTGTACACCAAAGCCAAGACCGATGTACGCGAGGATGTTCCTTTGTCCGAGCTGCGTGTAGGCTTGAAATGCGGCGG
TTCGGATGGCTTCTCAGGTATCACCGCCAATCCGTTGCTGGGTATGTTCTCCGACTTCCTGATTGCACAGGGCGGTACTT
CCGTACTGACGGAGGTTCCCGAAATGTTCGGTGCGGAAACCATCCTGATGAACCGTTGCCGCACCAAGGAACTGTTCGAG
CAGACCGTACACCTGATTAATGACTTTAAGGAATATTTCCTGTCACACGGCGAACCAGTGGGCGAAAATCCGTCACCGGG
CAACAAGGCAGGTGGTATCTCCACCCTGGAAGACAAAGCGTTGGGATGTACCCAAAAATGCGGCAAAGCATACGTTGACG
GAGTTATGGGCTATGGCGACCGCCTGAAAGTGAAAGGTTTGAACTTGCTTTCCGCACCGGGCAACGATTTGGTAGCTGCC
ACCGCCCTCGCCTCCTGCGGCTGTCACATGGTGCTCTTCACTACCGGCCGCGGTACTCCGTTCGGTACGTTTGTTCCTAC
CATGAAGATTTCCACCAACTCCACTCTGGCTAAAAACAAACCGGGATGGATTGACTTCAATGCCGGAGTCATCGTAGAAA
ACGAACCGATGGAAAAGACCTGCGAACGCTTTATAGACTATATCATCCGTGTTGCCAGCGGAGAACCGGTAAACAATGAA
AAGAAGAATTATCGTGAAATCGCCATCTTCAAGACAGGCGTGACACTATAA

Upstream 100 bases:

>100_bases
GAAACAATGCAATTACATGCCCATCATCCTGCTTTCGGTGGAGAACGTGGATTTCTATCTGGATGCGCATAAAAAGTAAA
TCTGATAACTAAAAATAGAA

Downstream 100 bases:

>100_bases
TCCAATTTTATCCCCAACTTTCCCAATACCCTTACAGCCCTGCCTTCCCTGTTACGAAGGTGGGGCTGTGACCTTTTTCC
CCCATATATTGTTATACAGC

Product: altronate hydrolase

Products: NA

Alternate protein names: Altronic acid hydratase [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
METKYLKINPADNVVVAISDLKAGEAITVDGHAITLKEDVPAGHKVTLKDFAQGENIIKYGYPIGHAVTAVEQGRWINET
QIKTNLAGLLDYTYNPVSVDLNIPKKDLTFKGYRRKNGDVGIRNEVWIIPTVGCVNGIIGQLAEALRRETNCEGVDAIVA
FPHNYGCSQLGDDHENTKKILRDMILHPNAGAVLIVSLGCENNQPDVFREFLGDYDTDRVKFMVTQKVGDEFEEGMKILR
ELYTKAKTDVREDVPLSELRVGLKCGGSDGFSGITANPLLGMFSDFLIAQGGTSVLTEVPEMFGAETILMNRCRTKELFE
QTVHLINDFKEYFLSHGEPVGENPSPGNKAGGISTLEDKALGCTQKCGKAYVDGVMGYGDRLKVKGLNLLSAPGNDLVAA
TALASCGCHMVLFTTGRGTPFGTFVPTMKISTNSTLAKNKPGWIDFNAGVIVENEPMEKTCERFIDYIIRVASGEPVNNE
KKNYREIAIFKTGVTL

Sequences:

>Translated_496_residues
METKYLKINPADNVVVAISDLKAGEAITVDGHAITLKEDVPAGHKVTLKDFAQGENIIKYGYPIGHAVTAVEQGRWINET
QIKTNLAGLLDYTYNPVSVDLNIPKKDLTFKGYRRKNGDVGIRNEVWIIPTVGCVNGIIGQLAEALRRETNCEGVDAIVA
FPHNYGCSQLGDDHENTKKILRDMILHPNAGAVLIVSLGCENNQPDVFREFLGDYDTDRVKFMVTQKVGDEFEEGMKILR
ELYTKAKTDVREDVPLSELRVGLKCGGSDGFSGITANPLLGMFSDFLIAQGGTSVLTEVPEMFGAETILMNRCRTKELFE
QTVHLINDFKEYFLSHGEPVGENPSPGNKAGGISTLEDKALGCTQKCGKAYVDGVMGYGDRLKVKGLNLLSAPGNDLVAA
TALASCGCHMVLFTTGRGTPFGTFVPTMKISTNSTLAKNKPGWIDFNAGVIVENEPMEKTCERFIDYIIRVASGEPVNNE
KKNYREIAIFKTGVTL
>Mature_496_residues
METKYLKINPADNVVVAISDLKAGEAITVDGHAITLKEDVPAGHKVTLKDFAQGENIIKYGYPIGHAVTAVEQGRWINET
QIKTNLAGLLDYTYNPVSVDLNIPKKDLTFKGYRRKNGDVGIRNEVWIIPTVGCVNGIIGQLAEALRRETNCEGVDAIVA
FPHNYGCSQLGDDHENTKKILRDMILHPNAGAVLIVSLGCENNQPDVFREFLGDYDTDRVKFMVTQKVGDEFEEGMKILR
ELYTKAKTDVREDVPLSELRVGLKCGGSDGFSGITANPLLGMFSDFLIAQGGTSVLTEVPEMFGAETILMNRCRTKELFE
QTVHLINDFKEYFLSHGEPVGENPSPGNKAGGISTLEDKALGCTQKCGKAYVDGVMGYGDRLKVKGLNLLSAPGNDLVAA
TALASCGCHMVLFTTGRGTPFGTFVPTMKISTNSTLAKNKPGWIDFNAGVIVENEPMEKTCERFIDYIIRVASGEPVNNE
KKNYREIAIFKTGVTL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG2721

COG function: function code G; Altronate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789475, Length=494, Percent_Identity=56.8825910931174, Blast_Score=596, Evalue=1e-172,
Organism=Escherichia coli, GI1789516, Length=506, Percent_Identity=33.201581027668, Blast_Score=246, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.7 [H]

Molecular weight: Translated: 54214; Mature: 54214

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METKYLKINPADNVVVAISDLKAGEAITVDGHAITLKEDVPAGHKVTLKDFAQGENIIKY
CCCCEEEECCCCCEEEEEECCCCCCEEEECCEEEEEECCCCCCCEEEHHHHHCCCCEEEE
GYPIGHAVTAVEQGRWINETQIKTNLAGLLDYTYNPVSVDLNIPKKDLTFKGYRRKNGDV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCC
GIRNEVWIIPTVGCVNGIIGQLAEALRRETNCEGVDAIVAFPHNYGCSQLGDDHENTKKI
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCHHHHHHH
LRDMILHPNAGAVLIVSLGCENNQPDVFREFLGDYDTDRVKFMVTQKVGDEFEEGMKILR
HHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
ELYTKAKTDVREDVPLSELRVGLKCGGSDGFSGITANPLLGMFSDFLIAQGGTSVLTEVP
HHHHHHHCCHHHCCCHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EMFGAETILMNRCRTKELFEQTVHLINDFKEYFLSHGEPVGENPSPGNKAGGISTLEDKA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LGCTQKCGKAYVDGVMGYGDRLKVKGLNLLSAPGNDLVAATALASCGCHMVLFTTGRGTP
CCHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCC
FGTFVPTMKISTNSTLAKNKPGWIDFNAGVIVENEPMEKTCERFIDYIIRVASGEPVNNE
CCCCCCEEEECCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
KKNYREIAIFKTGVTL
CCCCEEEEEEECCCCC
>Mature Secondary Structure
METKYLKINPADNVVVAISDLKAGEAITVDGHAITLKEDVPAGHKVTLKDFAQGENIIKY
CCCCEEEECCCCCEEEEEECCCCCCEEEECCEEEEEECCCCCCCEEEHHHHHCCCCEEEE
GYPIGHAVTAVEQGRWINETQIKTNLAGLLDYTYNPVSVDLNIPKKDLTFKGYRRKNGDV
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCCCCC
GIRNEVWIIPTVGCVNGIIGQLAEALRRETNCEGVDAIVAFPHNYGCSQLGDDHENTKKI
CCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCCCHHHHHHH
LRDMILHPNAGAVLIVSLGCENNQPDVFREFLGDYDTDRVKFMVTQKVGDEFEEGMKILR
HHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHH
ELYTKAKTDVREDVPLSELRVGLKCGGSDGFSGITANPLLGMFSDFLIAQGGTSVLTEVP
HHHHHHHCCHHHCCCHHHHHEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
EMFGAETILMNRCRTKELFEQTVHLINDFKEYFLSHGEPVGENPSPGNKAGGISTLEDKA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LGCTQKCGKAYVDGVMGYGDRLKVKGLNLLSAPGNDLVAATALASCGCHMVLFTTGRGTP
CCHHHHHHHHHHHHHHCCCCEEEEECCEEECCCCCCHHHHHHHHHCCCEEEEEECCCCCC
FGTFVPTMKISTNSTLAKNKPGWIDFNAGVIVENEPMEKTCERFIDYIIRVASGEPVNNE
CCCCCCEEEECCCCCCCCCCCCEEEECCCEEEECCCHHHHHHHHHHHHHHHCCCCCCCCC
KKNYREIAIFKTGVTL
CCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 3038546 [H]