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The map label for this gene is polC [H]

Identifier: 150005552

GI number: 150005552

Start: 3844834

End: 3845322

Strand: Direct

Name: polC [H]

Synonym: BVU_3037

Alternate gene names: 150005552

Gene position: 3844834-3845322 (Clockwise)

Preceding gene: 150005550

Following gene: 150005553

Centisome position: 74.47

GC content: 45.6

Gene sequence:

>489_bases
ATGGATAATTTTGCAGCAATAGACTTCGAGACGGCAAATAATGAACGTACCAGCATATGTAGTGTAGGGGTGGTTATTGT
GAGAAATGGTGAGATAGCCGACCGGTTCTACAGCCTCGTTCATCCCGAACCGGATTACTATTTGTATTGGAACACCCGTA
TTCATGGATTGACACAGGAAGATACTGCCCATGCTCCTGTTTTTTCGGAAGTATGGAAGCAGGTTGCTCCTAAAATAGAG
GGGCTTCCGCTGGTTGCGCATAACAAAGCCTTTGATGAGGGGTGTTTGAAAGCCGTGTTCCGTACTTATTGTATGGATTA
TCCTGATTATGACTTTTATTGTACCTATCAGGCTTCCCGGAAGCTGAAAGGGTTGAGAAACCACCAGTTACATACGGTGG
CCGGTTTTTTTGGTTTTGAATTGGAGAATCACCATCATGCGCTGGCTGATGCTGAGGCGTGTGCATGGATTGCCAGACAG
ATTCTGTGA

Upstream 100 bases:

>100_bases
ATTTTGCTGCTGAGGTTTCAAAGATAGGGAATTGTACCGGAAAAAAGAATTTTGTATATCGCTTTTTTGTCGTACCTTTG
TCTGTGTAACGAAAAAAAGT

Downstream 100 bases:

>100_bases
GTTATAATTAAAGATTTATGATTTCTGAAACCCATGATACAAGAAGATACTTATAAAACCATTACAGACATTGCCGAAGG
CATATATACGGAGAAACGGA

Product: putative exonuclease/DNA polymerase III epsilon c

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MDNFAAIDFETANNERTSICSVGVVIVRNGEIADRFYSLVHPEPDYYLYWNTRIHGLTQEDTAHAPVFSEVWKQVAPKIE
GLPLVAHNKAFDEGCLKAVFRTYCMDYPDYDFYCTYQASRKLKGLRNHQLHTVAGFFGFELENHHHALADAEACAWIARQ
IL

Sequences:

>Translated_162_residues
MDNFAAIDFETANNERTSICSVGVVIVRNGEIADRFYSLVHPEPDYYLYWNTRIHGLTQEDTAHAPVFSEVWKQVAPKIE
GLPLVAHNKAFDEGCLKAVFRTYCMDYPDYDFYCTYQASRKLKGLRNHQLHTVAGFFGFELENHHHALADAEACAWIARQ
IL
>Mature_162_residues
MDNFAAIDFETANNERTSICSVGVVIVRNGEIADRFYSLVHPEPDYYLYWNTRIHGLTQEDTAHAPVFSEVWKQVAPKIE
GLPLVAHNKAFDEGCLKAVFRTYCMDYPDYDFYCTYQASRKLKGLRNHQLHTVAGFFGFELENHHHALADAEACAWIARQ
IL

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 18589; Mature: 18589

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNFAAIDFETANNERTSICSVGVVIVRNGEIADRFYSLVHPEPDYYLYWNTRIHGLTQE
CCCCEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEECCEEECCCCC
DTAHAPVFSEVWKQVAPKIEGLPLVAHNKAFDEGCLKAVFRTYCMDYPDYDFYCTYQASR
CCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
KLKGLRNHQLHTVAGFFGFELENHHHALADAEACAWIARQIL
HHCCCCCCCCEEEHHHHCEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDNFAAIDFETANNERTSICSVGVVIVRNGEIADRFYSLVHPEPDYYLYWNTRIHGLTQE
CCCCEEEEEECCCCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCEEEEECCEEECCCCC
DTAHAPVFSEVWKQVAPKIEGLPLVAHNKAFDEGCLKAVFRTYCMDYPDYDFYCTYQASR
CCCCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHHH
KLKGLRNHQLHTVAGFFGFELENHHHALADAEACAWIARQIL
HHCCCCCCCCEEEHHHHCEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]