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The map label for this gene is aroB [H]

Identifier: 150005507

GI number: 150005507

Start: 3789204

End: 3790118

Strand: Direct

Name: aroB [H]

Synonym: BVU_2991

Alternate gene names: 150005507

Gene position: 3789204-3790118 (Clockwise)

Preceding gene: 150005506

Following gene: 150005508

Centisome position: 73.39

GC content: 42.84

Gene sequence:

>915_bases
ATGGGAAAAGTGAATTATGCTGCTATTGATATTGGTTCTAACGCTGTGCGCCTTTTGATAAAAAGCATTGACAGGGAGGC
TGTGCAGGAGAAAAAAATTAAAAAAGTGATGATGCTTCGCGTACCCCTACGACTAGGGTTCGATGTTTTCTCCATAGGTG
AATTGTCCGAGAAGAAAGCGGATAAGCTGAGACGTTTGATGAAGGCTTTCCGTCAGTTGATGAAAATTTATGATGTGGAT
GATTACAGGGCATGTGCTACTTCGGCTATGCGGGACGCGCGTAACGGGAGGACGATAATCAAGAAAATCGAAAAGGATAC
AGGTATCCGCATTGAGATAATTGATGGTCAGGAAGAGGCTCGAATGATTTATAATAATCATATAGAGTGTATGGAAGACC
GTCTGGGTAATTATATGTATGTGGATGTGGGTGGTGGCAGTACAGAGATTAATCTGTTGACTAACGGTGAGTTGGTATGG
TCGGTGTCTTACAACATCGGTACGGTGCGTATGCTAAGTAATGCTGTTAAAGAAGGAACTTGGCAGCAAATGGAAGAAGA
GCTTATGAAAGTGACGGAAGGTGTTGCCGCGATCAATATCATCGGATCGGGTGGGAATATTAATAAGTTGTTCCGCCTGG
CAGATAAGAAGGATAAGAAGTTGCAACGTTTGCCGGTCAGTTCGTTGCAAACAGTCTATGATGTGTTGAAACCGCTGACT
CCGGAGGAAAGGGTAGAGGCATTCAGTCTAAAGCAAGACCGTGCCGATGTAATTGTGCCTGCTGCGGAAATTTTTCTGAA
AATTGCAGAAGTAGTGCATGCAGAATATATTTATGTTCCGGTCATTGGACTGTCTGATGGTATCATTGACAATCTGTATG
CCAAAAGCCTTGAGAAAGAAATGAAAGTTGAATAA

Upstream 100 bases:

>100_bases
GGAGAGAATCGTCCTTGGATATCGGAAGATAAGACAGCTTTCCGTTCGCAGGAGGAATTATACAAATATTATTTAAATGA
AAACAGAATAAAGGATTAAG

Downstream 100 bases:

>100_bases
ACTTTCATTTTAATACTGTTTGTATTGTACGACTTCAAAAATATTCGGTTTATCCTGATAAATTGTTGGAAATTAATAGT
TGAAGTTCCAAAATTTGCTA

Product: putative phosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MGKVNYAAIDIGSNAVRLLIKSIDREAVQEKKIKKVMMLRVPLRLGFDVFSIGELSEKKADKLRRLMKAFRQLMKIYDVD
DYRACATSAMRDARNGRTIIKKIEKDTGIRIEIIDGQEEARMIYNNHIECMEDRLGNYMYVDVGGGSTEINLLTNGELVW
SVSYNIGTVRMLSNAVKEGTWQQMEEELMKVTEGVAAINIIGSGGNINKLFRLADKKDKKLQRLPVSSLQTVYDVLKPLT
PEERVEAFSLKQDRADVIVPAAEIFLKIAEVVHAEYIYVPVIGLSDGIIDNLYAKSLEKEMKVE

Sequences:

>Translated_304_residues
MGKVNYAAIDIGSNAVRLLIKSIDREAVQEKKIKKVMMLRVPLRLGFDVFSIGELSEKKADKLRRLMKAFRQLMKIYDVD
DYRACATSAMRDARNGRTIIKKIEKDTGIRIEIIDGQEEARMIYNNHIECMEDRLGNYMYVDVGGGSTEINLLTNGELVW
SVSYNIGTVRMLSNAVKEGTWQQMEEELMKVTEGVAAINIIGSGGNINKLFRLADKKDKKLQRLPVSSLQTVYDVLKPLT
PEERVEAFSLKQDRADVIVPAAEIFLKIAEVVHAEYIYVPVIGLSDGIIDNLYAKSLEKEMKVE
>Mature_303_residues
GKVNYAAIDIGSNAVRLLIKSIDREAVQEKKIKKVMMLRVPLRLGFDVFSIGELSEKKADKLRRLMKAFRQLMKIYDVDD
YRACATSAMRDARNGRTIIKKIEKDTGIRIEIIDGQEEARMIYNNHIECMEDRLGNYMYVDVGGGSTEINLLTNGELVWS
VSYNIGTVRMLSNAVKEGTWQQMEEELMKVTEGVAAINIIGSGGNINKLFRLADKKDKKLQRLPVSSLQTVYDVLKPLTP
EERVEAFSLKQDRADVIVPAAEIFLKIAEVVHAEYIYVPVIGLSDGIIDNLYAKSLEKEMKVE

Specific function: Conversion Of Pppgpp To Ppgpp. Guanosine Pentaphosphate (Pppgpp) Is A Cytoplasmic Signaling Molecule Which Together With Ppgpp Controls The "Stringent Response", An Adaptive Process That Allows Bacteria To Respond To Amino Acid Starvation, Resulting In T

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI48994966, Length=176, Percent_Identity=28.9772727272727, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788848, Length=164, Percent_Identity=29.8780487804878, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 34369; Mature: 34237

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVNYAAIDIGSNAVRLLIKSIDREAVQEKKIKKVMMLRVPLRLGFDVFSIGELSEKKA
CCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
DKLRRLMKAFRQLMKIYDVDDYRACATSAMRDARNGRTIIKKIEKDTGIRIEIIDGQEEA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCHHH
RMIYNNHIECMEDRLGNYMYVDVGGGSTEINLLTNGELVWSVSYNIGTVRMLSNAVKEGT
HHHHHCCHHHHHHHCCCEEEEEECCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHCCH
WQQMEEELMKVTEGVAAINIIGSGGNINKLFRLADKKDKKLQRLPVSSLQTVYDVLKPLT
HHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCC
PEERVEAFSLKQDRADVIVPAAEIFLKIAEVVHAEYIYVPVIGLSDGIIDNLYAKSLEKE
CHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHH
MKVE
HCCC
>Mature Secondary Structure 
GKVNYAAIDIGSNAVRLLIKSIDREAVQEKKIKKVMMLRVPLRLGFDVFSIGELSEKKA
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCHHHHHHH
DKLRRLMKAFRQLMKIYDVDDYRACATSAMRDARNGRTIIKKIEKDTGIRIEIIDGQEEA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCCHHH
RMIYNNHIECMEDRLGNYMYVDVGGGSTEINLLTNGELVWSVSYNIGTVRMLSNAVKEGT
HHHHHCCHHHHHHHCCCEEEEEECCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHCCH
WQQMEEELMKVTEGVAAINIIGSGGNINKLFRLADKKDKKLQRLPVSSLQTVYDVLKPLT
HHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCC
PEERVEAFSLKQDRADVIVPAAEIFLKIAEVVHAEYIYVPVIGLSDGIIDNLYAKSLEKE
CHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCEEEEEEEECCCHHHHHHHHHHHHHH
MKVE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]