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The map label for this gene is bioD [H]

Identifier: 150005309

GI number: 150005309

Start: 3552381

End: 3553025

Strand: Direct

Name: bioD [H]

Synonym: BVU_2783

Alternate gene names: 150005309

Gene position: 3552381-3553025 (Clockwise)

Preceding gene: 150005308

Following gene: 150005311

Centisome position: 68.8

GC content: 41.09

Gene sequence:

>645_bases
ATGAAACAGAATGTATTTTTCGTAAGTGGTATTGATACAAATATTGGTAAAAGTTATGCCACGGCCTATCTGGCACATCT
TTGGAACAAACAAGGATGTCGTACTATTACTCAAAAATTCATACAGACAGGAAATCCGGAAGGTTATTCGGAGGATATTG
AGTTGCATCGTCGTCTGATGGGGATGGAGTATTTGCCTGAGGATGAGCAGGGACTTACCAAACCTGAAATATTTTCTTAT
CCGGCTTCTCCCCATTTGGCTTCACGAATAGATAACCGCGCCATTGATTTTGATAAAATAAAGCATGCCACGGAGGTGCT
GAGTGAGCGCTATGATGCTGTTTTAGTAGAAGGAGCCGGGGGGCTGATGGTGCCGTTGACAGAAGATAATCTGACTATAG
ACTATGTTCAGGAATCGGGTTATCCCTTAGTTTTTGTTACTTCGGGACGATTGGGAAGTATCAACCATACATTATTGAGT
TTTGAGGCTATAGAACGGAGAGGGATAAAGCTTCATACAGTGATGTACAATCTGTTTCCCGAAGGAGAGGATAAAATCAT
TCAAGCAGATACAGAAACTTATATTTGTCGTTATATAGAGAAGCATTTCCCGGATACAGCATTTGTGAAGGTACCTTGCT
TGTAA

Upstream 100 bases:

>100_bases
ACAAGTATGCCCGTTTGTTCAGTGATGGTCGTTCGGTGACTTTGACTTATCATCCTATTTATATTATTGCAAAGAAAAGA
CAATAGAAATAAAAAGAATC

Downstream 100 bases:

>100_bases
TTCATCTTTCTTGTTTATGATGTGTTTACCTGATAAAAAGAGGTTGTTCTACATCTGACGACCTCTTTTTATTAGTTGTA
TCCATAATTTTCCGCTTAAG

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKQNVFFVSGIDTNIGKSYATAYLAHLWNKQGCRTITQKFIQTGNPEGYSEDIELHRRLMGMEYLPEDEQGLTKPEIFSY
PASPHLASRIDNRAIDFDKIKHATEVLSERYDAVLVEGAGGLMVPLTEDNLTIDYVQESGYPLVFVTSGRLGSINHTLLS
FEAIERRGIKLHTVMYNLFPEGEDKIIQADTETYICRYIEKHFPDTAFVKVPCL

Sequences:

>Translated_214_residues
MKQNVFFVSGIDTNIGKSYATAYLAHLWNKQGCRTITQKFIQTGNPEGYSEDIELHRRLMGMEYLPEDEQGLTKPEIFSY
PASPHLASRIDNRAIDFDKIKHATEVLSERYDAVLVEGAGGLMVPLTEDNLTIDYVQESGYPLVFVTSGRLGSINHTLLS
FEAIERRGIKLHTVMYNLFPEGEDKIIQADTETYICRYIEKHFPDTAFVKVPCL
>Mature_214_residues
MKQNVFFVSGIDTNIGKSYATAYLAHLWNKQGCRTITQKFIQTGNPEGYSEDIELHRRLMGMEYLPEDEQGLTKPEIFSY
PASPHLASRIDNRAIDFDKIKHATEVLSERYDAVLVEGAGGLMVPLTEDNLTIDYVQESGYPLVFVTSGRLGSINHTLLS
FEAIERRGIKLHTVMYNLFPEGEDKIIQADTETYICRYIEKHFPDTAFVKVPCL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=185, Percent_Identity=31.3513513513514, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24301; Mature: 24301

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQNVFFVSGIDTNIGKSYATAYLAHLWNKQGCRTITQKFIQTGNPEGYSEDIELHRRLM
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GMEYLPEDEQGLTKPEIFSYPASPHLASRIDNRAIDFDKIKHATEVLSERYDAVLVEGAG
CCCCCCCCCCCCCCCHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
GLMVPLTEDNLTIDYVQESGYPLVFVTSGRLGSINHTLLSFEAIERRGIKLHTVMYNLFP
CEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
EGEDKIIQADTETYICRYIEKHFPDTAFVKVPCL
CCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCC
>Mature Secondary Structure
MKQNVFFVSGIDTNIGKSYATAYLAHLWNKQGCRTITQKFIQTGNPEGYSEDIELHRRLM
CCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GMEYLPEDEQGLTKPEIFSYPASPHLASRIDNRAIDFDKIKHATEVLSERYDAVLVEGAG
CCCCCCCCCCCCCCCHHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
GLMVPLTEDNLTIDYVQESGYPLVFVTSGRLGSINHTLLSFEAIERRGIKLHTVMYNLFP
CEEEEEECCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEECCC
EGEDKIIQADTETYICRYIEKHFPDTAFVKVPCL
CCCCCEEEECHHHHHHHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]