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The map label for this gene is degP [C]

Identifier: 150005265

GI number: 150005265

Start: 3493155

End: 3494678

Strand: Direct

Name: degP [C]

Synonym: BVU_2737

Alternate gene names: 150005265

Gene position: 3493155-3494678 (Clockwise)

Preceding gene: 150005264

Following gene: 150005266

Centisome position: 67.65

GC content: 46.46

Gene sequence:

>1524_bases
ATGAAACAAGCAACTAAAATGGTACTAGGCGCAGCAGCAATTGTAGCAGTCAGCGCAGGTGTAGCAGGAGTAACGGCTTA
TTCTATGTTGAAACCCGAGCCAAACAAAAGCGTGGCTTTTAATGATGTGTTCCAACAAAATCCGAATACAAGACTCGCCG
CGTTGGACGCCACTCAAATGCAACCGGTGGATTTGACTCAGGCAGCGGAAAATTCAGTGCATGCAGTAGTTCATATAAAG
TCAACTCAAGAATCAAAGACTCAGACGGTTACCGTTCGTGATCCGTTCTATGATTTCTTTGGTGATATTTTTGGAAATGG
CAGAGGCGGCGGTCAGCAGCGTCAGGTGCAGACTCCTGAAAGAGTGGGATTCGGTTCCGGAGTGATCATCTCGAAAGATG
GATATATTGTAACGAATAACCATGTAATCGATAATGCTGATGTGATCAGTGTCAAACTGAATGACGGACGTGAATACAAG
GGACGTGTAATCGGCACAGACCCCAGCACGGATTTAGCGTTGGTTAAAATTGAAGCGGATGAGCTTCCTACGATTCCCGT
GGGCAATTCGGAGGCTTTGAAAGTAGGTGAGTGGGTATTGGCTGTGGGTAATCCCTTTAATATGACTTCTACGGTAACAG
CCGGTATTGTGAGTGCCAAAGCCCGTTCTTTAGGGGTATATAATAATGGTGTGGAATCTTTCATCCAGACAGATGCTGCG
ATCAACCAAGGCAACAGTGGTGGTGCATTGGTGAATGCAAGGGGTGAACTGGTAGGTATCAATTCCGTACTTTATTCACC
TACAGGAGCTTATTCGGGTTATGGGTTTGCTATTCCAACCAGTATTATGACGAAAGTTATAGCCGACTTGAAAGAATATG
GAACCGTTCAGCGTGCGGTATTGGGCATCAAGGGTACTCCGATTAATGATGACCAGCAGATGATGCCGGAAGAAATCAAG
AAGAAGGTGAAGGAACTGGGCGCCACCGACGGTGTGTTGATTGCTGAGATAATTGAGGGAGGTTCTGCGGCCGGCAACTT
GGAAGTAGATGATGTCATTATCGGTATTGACGGAAAACGTGTGAAGAACTTTGCTGAGTTGCAGGAGGGGTTGGCTAAAC
ACCGTCCGGGTGACAAAGTAACCGTCAAGGTGTTGCGTGACAAGAAAGAAAAGGATATCGAGATGACCTTGAAGAATGCA
CAGGGAACAACGAAAGTGGTGAAGAGTGCGGGCATGGATATCTTGGGCGCAGCATTCCGTGAAGTTCCTCAGGAATTGAA
GAGACAATTGAATTTGGGATATGGTGTGGAAGTCACAGGTGTGACAGACGGTAAGATGAAGGCTGCCGGTATCCGTAAAG
GCTTCATCATCCTGAAGGCAAATGGACAACCTGTCAAATCAGTAAATGATTTGGAAGATGTGCTGAAAGCTGCTACCCAG
TCACCGGATCAGGTATTGTTCCTGAGTGGTATGTTCCCATCAGGTAAACGTGCGAACTATGCAGTGGATTTGACACAGGA
ATAA

Upstream 100 bases:

>100_bases
AAACTCTGACAAACGGTACAACCGTACAATATTTGTCATTACATTAGCGTCATAAATGTTAAACCAAACTTGAAATTAAC
AAATTAATAGATATTAAGTT

Downstream 100 bases:

>100_bases
GAAGATTTTTAAGGTAGAAAGTTTCAATAGGTAAAGTTTAGAGGATGCACGGTAAGGGTTACTTCCGTGCATCCTGATTT
TATAGTCAAACAGGACTGAT

Product: serine protease precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 507

Protein sequence:

>507_residues
MKQATKMVLGAAAIVAVSAGVAGVTAYSMLKPEPNKSVAFNDVFQQNPNTRLAALDATQMQPVDLTQAAENSVHAVVHIK
STQESKTQTVTVRDPFYDFFGDIFGNGRGGGQQRQVQTPERVGFGSGVIISKDGYIVTNNHVIDNADVISVKLNDGREYK
GRVIGTDPSTDLALVKIEADELPTIPVGNSEALKVGEWVLAVGNPFNMTSTVTAGIVSAKARSLGVYNNGVESFIQTDAA
INQGNSGGALVNARGELVGINSVLYSPTGAYSGYGFAIPTSIMTKVIADLKEYGTVQRAVLGIKGTPINDDQQMMPEEIK
KKVKELGATDGVLIAEIIEGGSAAGNLEVDDVIIGIDGKRVKNFAELQEGLAKHRPGDKVTVKVLRDKKEKDIEMTLKNA
QGTTKVVKSAGMDILGAAFREVPQELKRQLNLGYGVEVTGVTDGKMKAAGIRKGFIILKANGQPVKSVNDLEDVLKAATQ
SPDQVLFLSGMFPSGKRANYAVDLTQE

Sequences:

>Translated_507_residues
MKQATKMVLGAAAIVAVSAGVAGVTAYSMLKPEPNKSVAFNDVFQQNPNTRLAALDATQMQPVDLTQAAENSVHAVVHIK
STQESKTQTVTVRDPFYDFFGDIFGNGRGGGQQRQVQTPERVGFGSGVIISKDGYIVTNNHVIDNADVISVKLNDGREYK
GRVIGTDPSTDLALVKIEADELPTIPVGNSEALKVGEWVLAVGNPFNMTSTVTAGIVSAKARSLGVYNNGVESFIQTDAA
INQGNSGGALVNARGELVGINSVLYSPTGAYSGYGFAIPTSIMTKVIADLKEYGTVQRAVLGIKGTPINDDQQMMPEEIK
KKVKELGATDGVLIAEIIEGGSAAGNLEVDDVIIGIDGKRVKNFAELQEGLAKHRPGDKVTVKVLRDKKEKDIEMTLKNA
QGTTKVVKSAGMDILGAAFREVPQELKRQLNLGYGVEVTGVTDGKMKAAGIRKGFIILKANGQPVKSVNDLEDVLKAATQ
SPDQVLFLSGMFPSGKRANYAVDLTQE
>Mature_507_residues
MKQATKMVLGAAAIVAVSAGVAGVTAYSMLKPEPNKSVAFNDVFQQNPNTRLAALDATQMQPVDLTQAAENSVHAVVHIK
STQESKTQTVTVRDPFYDFFGDIFGNGRGGGQQRQVQTPERVGFGSGVIISKDGYIVTNNHVIDNADVISVKLNDGREYK
GRVIGTDPSTDLALVKIEADELPTIPVGNSEALKVGEWVLAVGNPFNMTSTVTAGIVSAKARSLGVYNNGVESFIQTDAA
INQGNSGGALVNARGELVGINSVLYSPTGAYSGYGFAIPTSIMTKVIADLKEYGTVQRAVLGIKGTPINDDQQMMPEEIK
KKVKELGATDGVLIAEIIEGGSAAGNLEVDDVIIGIDGKRVKNFAELQEGLAKHRPGDKVTVKVLRDKKEKDIEMTLKNA
QGTTKVVKSAGMDILGAAFREVPQELKRQLNLGYGVEVTGVTDGKMKAAGIRKGFIILKANGQPVKSVNDLEDVLKAATQ
SPDQVLFLSGMFPSGKRANYAVDLTQE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=272, Percent_Identity=36.0294117647059, Blast_Score=149, Evalue=7e-36,
Organism=Homo sapiens, GI4506141, Length=251, Percent_Identity=37.4501992031873, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI22129776, Length=266, Percent_Identity=32.3308270676692, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI7019477, Length=285, Percent_Identity=34.7368421052632, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1786356, Length=360, Percent_Identity=41.1111111111111, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI1789629, Length=417, Percent_Identity=36.9304556354916, Blast_Score=238, Evalue=7e-64,
Organism=Escherichia coli, GI1789630, Length=288, Percent_Identity=40.2777777777778, Blast_Score=193, Evalue=2e-50,
Organism=Drosophila melanogaster, GI24646839, Length=289, Percent_Identity=32.5259515570934, Blast_Score=142, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 53837; Mature: 53837

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQATKMVLGAAAIVAVSAGVAGVTAYSMLKPEPNKSVAFNDVFQQNPNTRLAALDATQM
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCEEEEECCCCC
QPVDLTQAAENSVHAVVHIKSTQESKTQTVTVRDPFYDFFGDIFGNGRGGGQQRQVQTPE
CCCCHHHHHCCCEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHH
RVGFGSGVIISKDGYIVTNNHVIDNADVISVKLNDGREYKGRVIGTDPSTDLALVKIEAD
HCCCCCCEEEECCCEEEECCEEECCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEEECC
ELPTIPVGNSEALKVGEWVLAVGNPFNMTSTVTAGIVSAKARSLGVYNNGVESFIQTDAA
CCCCCCCCCCCCEEECEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
INQGNSGGALVNARGELVGINSVLYSPTGAYSGYGFAIPTSIMTKVIADLKEYGTVQRAV
HCCCCCCCEEEECCCCEEEECCEEECCCCCCCCCCEECCHHHHHHHHHHHHHHCCHHHHH
LGIKGTPINDDQQMMPEEIKKKVKELGATDGVLIAEIIEGGSAAGNLEVDDVIIGIDGKR
EECCCCCCCCHHHHCHHHHHHHHHHCCCCCCEEHHHHHCCCCCCCCEEECEEEEECCCHH
VKNFAELQEGLAKHRPGDKVTVKVLRDKKEKDIEMTLKNAQGTTKVVKSAGMDILGAAFR
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHH
EVPQELKRQLNLGYGVEVTGVTDGKMKAAGIRKGFIILKANGQPVKSVNDLEDVLKAATQ
HHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHC
SPDQVLFLSGMFPSGKRANYAVDLTQE
CCCEEEEEECCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MKQATKMVLGAAAIVAVSAGVAGVTAYSMLKPEPNKSVAFNDVFQQNPNTRLAALDATQM
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEHHHHHCCCCCEEEEECCCCC
QPVDLTQAAENSVHAVVHIKSTQESKTQTVTVRDPFYDFFGDIFGNGRGGGQQRQVQTPE
CCCCHHHHHCCCEEEEEEEECCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCCHH
RVGFGSGVIISKDGYIVTNNHVIDNADVISVKLNDGREYKGRVIGTDPSTDLALVKIEAD
HCCCCCCEEEECCCEEEECCEEECCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEEECC
ELPTIPVGNSEALKVGEWVLAVGNPFNMTSTVTAGIVSAKARSLGVYNNGVESFIQTDAA
CCCCCCCCCCCCEEECEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
INQGNSGGALVNARGELVGINSVLYSPTGAYSGYGFAIPTSIMTKVIADLKEYGTVQRAV
HCCCCCCCEEEECCCCEEEECCEEECCCCCCCCCCEECCHHHHHHHHHHHHHHCCHHHHH
LGIKGTPINDDQQMMPEEIKKKVKELGATDGVLIAEIIEGGSAAGNLEVDDVIIGIDGKR
EECCCCCCCCHHHHCHHHHHHHHHHCCCCCCEEHHHHHCCCCCCCCEEECEEEEECCCHH
VKNFAELQEGLAKHRPGDKVTVKVLRDKKEKDIEMTLKNAQGTTKVVKSAGMDILGAAFR
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEECCCCHHHHHHHCCCHHHHHHHH
EVPQELKRQLNLGYGVEVTGVTDGKMKAAGIRKGFIILKANGQPVKSVNDLEDVLKAATQ
HHHHHHHHHCCCCCCEEEEECCCCCEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHHC
SPDQVLFLSGMFPSGKRANYAVDLTQE
CCCEEEEEECCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]