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The map label for this gene is cirA [H]

Identifier: 150005256

GI number: 150005256

Start: 3473657

End: 3475990

Strand: Direct

Name: cirA [H]

Synonym: BVU_2728

Alternate gene names: 150005256

Gene position: 3473657-3475990 (Clockwise)

Preceding gene: 150005255

Following gene: 150005258

Centisome position: 67.28

GC content: 47.73

Gene sequence:

>2334_bases
ATGAAACAATATATTCTGTTACTCGTGCTCATGGTGATGGGTGCGGGTATCCATGCGTATGCAGAAGATGTAAATCCTGT
GAAGGAAGGAAATGTGATTTCAGGTCATGTAGTGGAAAAAGGCACGGAGAACAGCCTTCCGTATGCTACCATATTGATTG
TGGAAACCGGGCAAGGTACGGTGAGTAACGAGGACGGGGAGTTCCGTTTCAAGAAGGTTCCGGCAGGAAAGTACACATTG
AGAGTTCAGCTACTGGGCTATGAGACACAGGAAAAGAAAGTGACCGTCAGTAACGACTTCACGGTAGATGTTCATTTTTT
GATGAGTGACGAAAGTATTATGACGGACGAGGTAGTCGTATCGGCCAATCGCAATGAAACAAGTCGCAAGGTGGCTCCGG
TGGTAGTCAATGTGATGAATGCCAGGCTTTTCGAATCGGTGAATTCTACCGATTTGGCTAAATCCTTGAATTACCAGTCG
GGGTTGCGTGTGGAGAACAACTGCCAGAACTGCGGCTTCCCTCAAGTGCGTATCAATGGGCTGGAAGGGCCTTATTCTCA
GATTCTTATCAATAGCCGTCCGGTAGTCAGTGCTCTGTCCGGTGTGTATGGCTTGGAGCAGATTCCGGTGAATATGATAG
AGCGTGTAGAGGTTGTCCGCGGAGGAGGGTCGGCCTTGTTTGGTGCTAATGCAGTGGGCGGAACCATCAATATCATCACG
AAAGACCCCATCAACAATTCATTTCAGGTTTCTTCAACAATGTCCAATATGAACGGCAAGGTGTGGGAACAGTATATGGG
AGCCAATGCCTCTTTGGTGTCAAAAGACAATACGTATGGCATCGCTTTGTATCAGTCTTATCGGAACCGTAATCCGTATG
ATGCGGACGGGGACGGTTTCTCGGAGTTGGGAAAGCTGAATATGAATACATTCGGGCTGCGCACCTATTACCGTCCTACG
CAGTTCAGCCGTATCAGTCTGGAATATCATACCACGAATGAGTTCCGCCGCGGAGGGAATAAATTTGATTTGCAGCCGCA
CGAAACGGATATCACCGAACAGACCAAGCACGTTATCAATAGTGGCGGATTGAGTTATGATCTGTTTTGGAAAGAATACA
AGCATAAGCTTTCTTTCTATTCTTCCATCCAGCATACCGACCGTAACAGTTATTATGGTGCGCAACAGGATGCGAATGCA
TACGGAAAGACAAAAGATCTGACTTGGGTGGCAGGCGGCATGTATGTGGGTAATTTTGAGAAAGTTTTATTCTCTCCTGC
TACTTTTACCGCCGGGCTGGAGTATCAGAACAACTCCCTGCACGATGTTATGACCGGTTATCACCGTGATATGAAACAGG
ATGTGCGCATTGCCAGCGCTTTTGTGCAGAACGAATGGAAAATGAATCAGTTTGTATTCCTGGCCGGCTTCCGTCTGGAT
GACCATAACCTGATTGACAATCCCATCTTCAGCCCCCGTCTGAACCTGCTCTATAAGCCCAGTGACAAACTACAGGCGCG
CATCACTTGGTCCACCGGTTTCCGTGCGCCGCAGGCTTATGATGAAGACTTGCACGTTACGGCAGTAGGAGGTGAGGGCG
TGCTTATCAAGTTGGCGGAAGGGCTGAAGCCTGAGCATTCTAACAGCATCAGCGGCTCCATTGACTGGACGGCGAATATC
GGTCATTTCCAGACCAATTTGTTATTGGAAGGATTCTATACCGGATTGGATGACGTGTTTGTACTGGAGGATATGGGCCA
TGACCAGAATGGTAACAAGGTGAAGGAGCGTCGTAACGGTAACGGGGCACGTGTGTATGGCGTGAATCTGGACGGAAAGA
TTGCACATGGACGTGATGCGGCTTTACAGGTGGGCTTCACGGTGCAGCGCAGCGAATATACTGAGCTGGAGGCATGGAGT
GAGAATCCTGAGGTAGCGCCGGTGAAGCGGATGCCCCGTACTCCTGACTATTACGGTTATTTCACATTGACATCTGCTCC
GTTCAAGAATTTCGACTGCTCCTTGTCCGGTGTGTACACAGGCCGGATGCATGTGCCGCATTTCGCACCGACAGAGTTGC
CCGAGGAATATATAGGACAATATATCGCTAAAGATGAAATGGTGCATACTCCTGATTTCTTTGATTTGAATGTGAAACTG
AATTATACGTTTGTATTGAATGACCATATCAAGTTGCAATTGAACGGTGGAGTGCAGAATATCTTTAATGCTTTCCAAAA
GGATTTGGACAAAGGTGGTTATCGTGACTCGGGTTATTTCTATGGGCCTACACAGCCTAGAACGTATTTTGTGGGGATCA
AGATTACGAATTGA

Upstream 100 bases:

>100_bases
TCGGATAATCCGTTCAACAGATGCGGATGTGCTTTTGCCGTAGAGCTGCACACATTCTTTAATTGAATAAACCGAAACAT
TTTAGTAATAGAAAAAATAG

Downstream 100 bases:

>100_bases
ATAATCTGCTGATTGGTCAATGTGCTAATATGTCAATGGGTTACGCTTTGTTCCACATGGCACATTAGCACATTGTCACA
TTGACAAATTAGCAGATTGA

Product: TonB-dependent outer membrane receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MKQYILLLVLMVMGAGIHAYAEDVNPVKEGNVISGHVVEKGTENSLPYATILIVETGQGTVSNEDGEFRFKKVPAGKYTL
RVQLLGYETQEKKVTVSNDFTVDVHFLMSDESIMTDEVVVSANRNETSRKVAPVVVNVMNARLFESVNSTDLAKSLNYQS
GLRVENNCQNCGFPQVRINGLEGPYSQILINSRPVVSALSGVYGLEQIPVNMIERVEVVRGGGSALFGANAVGGTINIIT
KDPINNSFQVSSTMSNMNGKVWEQYMGANASLVSKDNTYGIALYQSYRNRNPYDADGDGFSELGKLNMNTFGLRTYYRPT
QFSRISLEYHTTNEFRRGGNKFDLQPHETDITEQTKHVINSGGLSYDLFWKEYKHKLSFYSSIQHTDRNSYYGAQQDANA
YGKTKDLTWVAGGMYVGNFEKVLFSPATFTAGLEYQNNSLHDVMTGYHRDMKQDVRIASAFVQNEWKMNQFVFLAGFRLD
DHNLIDNPIFSPRLNLLYKPSDKLQARITWSTGFRAPQAYDEDLHVTAVGGEGVLIKLAEGLKPEHSNSISGSIDWTANI
GHFQTNLLLEGFYTGLDDVFVLEDMGHDQNGNKVKERRNGNGARVYGVNLDGKIAHGRDAALQVGFTVQRSEYTELEAWS
ENPEVAPVKRMPRTPDYYGYFTLTSAPFKNFDCSLSGVYTGRMHVPHFAPTELPEEYIGQYIAKDEMVHTPDFFDLNVKL
NYTFVLNDHIKLQLNGGVQNIFNAFQKDLDKGGYRDSGYFYGPTQPRTYFVGIKITN

Sequences:

>Translated_777_residues
MKQYILLLVLMVMGAGIHAYAEDVNPVKEGNVISGHVVEKGTENSLPYATILIVETGQGTVSNEDGEFRFKKVPAGKYTL
RVQLLGYETQEKKVTVSNDFTVDVHFLMSDESIMTDEVVVSANRNETSRKVAPVVVNVMNARLFESVNSTDLAKSLNYQS
GLRVENNCQNCGFPQVRINGLEGPYSQILINSRPVVSALSGVYGLEQIPVNMIERVEVVRGGGSALFGANAVGGTINIIT
KDPINNSFQVSSTMSNMNGKVWEQYMGANASLVSKDNTYGIALYQSYRNRNPYDADGDGFSELGKLNMNTFGLRTYYRPT
QFSRISLEYHTTNEFRRGGNKFDLQPHETDITEQTKHVINSGGLSYDLFWKEYKHKLSFYSSIQHTDRNSYYGAQQDANA
YGKTKDLTWVAGGMYVGNFEKVLFSPATFTAGLEYQNNSLHDVMTGYHRDMKQDVRIASAFVQNEWKMNQFVFLAGFRLD
DHNLIDNPIFSPRLNLLYKPSDKLQARITWSTGFRAPQAYDEDLHVTAVGGEGVLIKLAEGLKPEHSNSISGSIDWTANI
GHFQTNLLLEGFYTGLDDVFVLEDMGHDQNGNKVKERRNGNGARVYGVNLDGKIAHGRDAALQVGFTVQRSEYTELEAWS
ENPEVAPVKRMPRTPDYYGYFTLTSAPFKNFDCSLSGVYTGRMHVPHFAPTELPEEYIGQYIAKDEMVHTPDFFDLNVKL
NYTFVLNDHIKLQLNGGVQNIFNAFQKDLDKGGYRDSGYFYGPTQPRTYFVGIKITN
>Mature_777_residues
MKQYILLLVLMVMGAGIHAYAEDVNPVKEGNVISGHVVEKGTENSLPYATILIVETGQGTVSNEDGEFRFKKVPAGKYTL
RVQLLGYETQEKKVTVSNDFTVDVHFLMSDESIMTDEVVVSANRNETSRKVAPVVVNVMNARLFESVNSTDLAKSLNYQS
GLRVENNCQNCGFPQVRINGLEGPYSQILINSRPVVSALSGVYGLEQIPVNMIERVEVVRGGGSALFGANAVGGTINIIT
KDPINNSFQVSSTMSNMNGKVWEQYMGANASLVSKDNTYGIALYQSYRNRNPYDADGDGFSELGKLNMNTFGLRTYYRPT
QFSRISLEYHTTNEFRRGGNKFDLQPHETDITEQTKHVINSGGLSYDLFWKEYKHKLSFYSSIQHTDRNSYYGAQQDANA
YGKTKDLTWVAGGMYVGNFEKVLFSPATFTAGLEYQNNSLHDVMTGYHRDMKQDVRIASAFVQNEWKMNQFVFLAGFRLD
DHNLIDNPIFSPRLNLLYKPSDKLQARITWSTGFRAPQAYDEDLHVTAVGGEGVLIKLAEGLKPEHSNSISGSIDWTANI
GHFQTNLLLEGFYTGLDDVFVLEDMGHDQNGNKVKERRNGNGARVYGVNLDGKIAHGRDAALQVGFTVQRSEYTELEAWS
ENPEVAPVKRMPRTPDYYGYFTLTSAPFKNFDCSLSGVYTGRMHVPHFAPTELPEEYIGQYIAKDEMVHTPDFFDLNVKL
NYTFVLNDHIKLQLNGGVQNIFNAFQKDLDKGGYRDSGYFYGPTQPRTYFVGIKITN

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=446, Percent_Identity=25.3363228699552, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790405, Length=126, Percent_Identity=30.952380952381, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 87162; Mature: 87162

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQYILLLVLMVMGAGIHAYAEDVNPVKEGNVISGHVVEKGTENSLPYATILIVETGQGT
CHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCEEECEEECCCCCCCCCEEEEEEEECCCCC
VSNEDGEFRFKKVPAGKYTLRVQLLGYETQEKKVTVSNDFTVDVHFLMSDESIMTDEVVV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCEEEEEEEEECCCCEECCEEEE
SANRNETSRKVAPVVVNVMNARLFESVNSTDLAKSLNYQSGLRVENNCQNCGFPQVRING
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
LEGPYSQILINSRPVVSALSGVYGLEQIPVNMIERVEVVRGGGSALFGANAVGGTINIIT
CCCCCHHEEECCCCHHHHHHHHCCHHHCCHHHHHHHHEEECCCCEEEECCCCCCEEEEEE
KDPINNSFQVSSTMSNMNGKVWEQYMGANASLVSKDNTYGIALYQSYRNRNPYDADGDGF
ECCCCCCEEEEHHHHHCCHHHHHHHHCCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCCH
SELGKLNMNTFGLRTYYRPTQFSRISLEYHTTNEFRRGGNKFDLQPHETDITEQTKHVIN
HHHCCCCCCEEEEEEEECCCCCEEEEEEEECCHHHHCCCCEECCCCCCCCHHHHHHHHHH
SGGLSYDLFWKEYKHKLSFYSSIQHTDRNSYYGAQQDANAYGKTKDLTWVAGGMYVGNFE
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCH
KVLFSPATFTAGLEYQNNSLHDVMTGYHRDMKQDVRIASAFVQNEWKMNQFVFLAGFRLD
HEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEC
DHNLIDNPIFSPRLNLLYKPSDKLQARITWSTGFRAPQAYDEDLHVTAVGGEGVLIKLAE
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEC
GLKPEHSNSISGSIDWTANIGHFQTNLLLEGFYTGLDDVFVLEDMGHDQNGNKVKERRNG
CCCCCCCCCCCCEEEEEECCCCEEEHEEEEHHHCCCCCEEEEECCCCCCCCCHHHHHCCC
NGARVYGVNLDGKIAHGRDAALQVGFTVQRSEYTELEAWSENPEVAPVKRMPRTPDYYGY
CCEEEEEECCCCEEECCCCCEEEEEEEEECCCCCCHHCCCCCCCCCHHHCCCCCCCCEEE
FTLTSAPFKNFDCSLSGVYTGRMHVPHFAPTELPEEYIGQYIAKDEMVHTPDFFDLNVKL
EEEECCCCCCCCCEEEEEEECCEECCCCCCCCCCHHHHHHHHHCCCEECCCCEEEEEEEE
NYTFVLNDHIKLQLNGGVQNIFNAFQKDLDKGGYRDSGYFYGPTQPRTYFVGIKITN
EEEEEEECEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEEECC
>Mature Secondary Structure
MKQYILLLVLMVMGAGIHAYAEDVNPVKEGNVISGHVVEKGTENSLPYATILIVETGQGT
CHHHHHHHHHHHHCCCCEEHHHCCCCCCCCCEEECEEECCCCCCCCCEEEEEEEECCCCC
VSNEDGEFRFKKVPAGKYTLRVQLLGYETQEKKVTVSNDFTVDVHFLMSDESIMTDEVVV
CCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEEEECCCEEEEEEEEECCCCEECCEEEE
SANRNETSRKVAPVVVNVMNARLFESVNSTDLAKSLNYQSGLRVENNCQNCGFPQVRING
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEC
LEGPYSQILINSRPVVSALSGVYGLEQIPVNMIERVEVVRGGGSALFGANAVGGTINIIT
CCCCCHHEEECCCCHHHHHHHHCCHHHCCHHHHHHHHEEECCCCEEEECCCCCCEEEEEE
KDPINNSFQVSSTMSNMNGKVWEQYMGANASLVSKDNTYGIALYQSYRNRNPYDADGDGF
ECCCCCCEEEEHHHHHCCHHHHHHHHCCCCEEEECCCCEEEEEEEHHCCCCCCCCCCCCH
SELGKLNMNTFGLRTYYRPTQFSRISLEYHTTNEFRRGGNKFDLQPHETDITEQTKHVIN
HHHCCCCCCEEEEEEEECCCCCEEEEEEEECCHHHHCCCCEECCCCCCCCHHHHHHHHHH
SGGLSYDLFWKEYKHKLSFYSSIQHTDRNSYYGAQQDANAYGKTKDLTWVAGGMYVGNFE
CCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCEEECCCH
KVLFSPATFTAGLEYQNNSLHDVMTGYHRDMKQDVRIASAFVQNEWKMNQFVFLAGFRLD
HEEECCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEC
DHNLIDNPIFSPRLNLLYKPSDKLQARITWSTGFRAPQAYDEDLHVTAVGGEGVLIKLAE
CCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCEEEEEECCCCEEEEEEC
GLKPEHSNSISGSIDWTANIGHFQTNLLLEGFYTGLDDVFVLEDMGHDQNGNKVKERRNG
CCCCCCCCCCCCEEEEEECCCCEEEHEEEEHHHCCCCCEEEEECCCCCCCCCHHHHHCCC
NGARVYGVNLDGKIAHGRDAALQVGFTVQRSEYTELEAWSENPEVAPVKRMPRTPDYYGY
CCEEEEEECCCCEEECCCCCEEEEEEEEECCCCCCHHCCCCCCCCCHHHCCCCCCCCEEE
FTLTSAPFKNFDCSLSGVYTGRMHVPHFAPTELPEEYIGQYIAKDEMVHTPDFFDLNVKL
EEEECCCCCCCCCEEEEEEECCEECCCCCCCCCCHHHHHHHHHCCCEECCCCEEEEEEEE
NYTFVLNDHIKLQLNGGVQNIFNAFQKDLDKGGYRDSGYFYGPTQPRTYFVGIKITN
EEEEEEECEEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]