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The map label for this gene is ribH

Identifier: 150005149

GI number: 150005149

Start: 3329180

End: 3329686

Strand: Reverse

Name: ribH

Synonym: BVU_2618

Alternate gene names: 150005149

Gene position: 3329686-3329180 (Counterclockwise)

Preceding gene: 150005150

Following gene: 150005148

Centisome position: 64.49

GC content: 39.84

Gene sequence:

>507_bases
ATGGCAACAGCGTATCATAACTTATCTGATTACGATTTCAATTCAGTTCCTAATGCAGAAAATATGCGTTTCGGTATCGT
AGTATCCGAATGGAACAATAACATTACCGGCCCCCTATTGGAAGGAGCCATAAGTACCTTGAAGAAACATGGCGCAAAAG
ATAAAAATATTTTAGTACAAACAGTACCCGGCAGTTTTGAACTGACTTTCGGTTCTGCACAAATGATAAAAAGTGGAAAA
GTAGATGCAGTGATTGCAATAGGCTGCGTAGTTCGTGGCGATACTCCGCACTTTGATTATGTATGTGCCGGTACCACTCA
AGGTATTGCCCAACTGAATGCCGAAGGAGATATTCCTGTAATCTATGGTTTGATTACTACCAATACTATGCAACAAGCAG
AAGACCGTGCCGGTGGAAGATTAGGAAATAAAGGGGATGAATGTGCAATAACTGCCATCAAAATGCTCGATTTTAAAGAG
AAATTGCAAAAAACGCAGATTTTTTGA

Upstream 100 bases:

>100_bases
TCAAATAAGAAAAGAATATACCTTAATGATATAAAGAGGTTGTCTGCACCTGTGTACAGATAACCTCTTTCTTTTATTAA
ACCACTAAAACTAAAAAACA

Downstream 100 bases:

>100_bases
AAAAAAGTTCTTGTATAATTTGCATATTCAAAAAAAAGCCGTACCTTTGCATCGCAATTGAGAAACAAACCTACTCAATG
AGAGAATTGAGATAGACTCT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQTVPGSFELTFGSAQMIKSGK
VDAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPVIYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKE
KLQKTQIF

Sequences:

>Translated_168_residues
MATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQTVPGSFELTFGSAQMIKSGK
VDAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPVIYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKE
KLQKTQIF
>Mature_167_residues
ATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQTVPGSFELTFGSAQMIKSGKV
DAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPVIYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKEK
LQKTQIF

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family

Homologues:

Organism=Escherichia coli, GI1786617, Length=144, Percent_Identity=44.4444444444444, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324429, Length=151, Percent_Identity=36.4238410596026, Blast_Score=105, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RISB_BACV8 (A6L3K7)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299893.1
- ProteinModelPortal:   A6L3K7
- SMR:   A6L3K7
- STRING:   A6L3K7
- GeneID:   5303581
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2618
- NMPDR:   fig|435590.6.peg.2457
- eggNOG:   COG0054
- HOGENOM:   HBG311126
- OMA:   KAGNKGW
- ProtClustDB:   PRK00061
- HAMAP:   MF_00178
- InterPro:   IPR002180
- Gene3D:   G3DSA:3.40.50.960
- PANTHER:   PTHR21058
- TIGRFAMs:   TIGR00114

Pfam domain/function: PF00885 DMRL_synthase; SSF52121 DMRL_synthase

EC number: =2.5.1.9

Molecular weight: Translated: 18128; Mature: 17997

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQ
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
TVPGSFELTFGSAQMIKSGKVDAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPV
ECCCCEEEEECCHHHHHCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCEEECCCCCCEE
IYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKEKLQKTQIF
EEEEEECCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATAYHNLSDYDFNSVPNAENMRFGIVVSEWNNNITGPLLEGAISTLKKHGAKDKNILVQ
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCEEEE
TVPGSFELTFGSAQMIKSGKVDAVIAIGCVVRGDTPHFDYVCAGTTQGIAQLNAEGDIPV
ECCCCEEEEECCHHHHHCCCCCEEEEEEEEEECCCCCCEEEECCCCCCCEEECCCCCCEE
IYGLITTNTMQQAEDRAGGRLGNKGDECAITAIKMLDFKEKLQKTQIF
EEEEEECCHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA