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The map label for this gene is murQ [H]

Identifier: 150005119

GI number: 150005119

Start: 3299565

End: 3300401

Strand: Reverse

Name: murQ [H]

Synonym: BVU_2586

Alternate gene names: 150005119

Gene position: 3300401-3299565 (Counterclockwise)

Preceding gene: 150005120

Following gene: 150005118

Centisome position: 63.92

GC content: 42.41

Gene sequence:

>837_bases
ATGAATTTTATAAAAATAACCGAACAACCGTCCATACATGAGGATTTGGAACAAAAATCCGTCAGAGAGTTACTGGAAGG
TATCAACGAAGAAGACCGGAAAGTAGCCTCAGCCGTTCATGCCTGCATACCACAAATTGAAAAACTAGTAAATGAAATAG
TAGAACGTATGCATCAAGGAGGACGCATATTCTATTTGGGAGCCGGAACCAGTGGACGCCTAGGAGTATTGGACGCTTCT
GAAATTCCACCCACTTTCGGTATGCCTGATACCTGTGTCATAGGTATTATAGCCGGTGGCGAACAGGCTTTGAGACGTCC
CGTAGAAAATGCTGAAGATGATAGTCAAAAAGGCTGGATGGAACTGCAAGACCATCACATCACAAATAAAGACATTCTGA
TAGGCATAGCGGCATCGGGAACAACTCCTTATGTAATAGGAGCACTGCAAAAAGCAAGAGAACACGGAATATTAACAGCA
AGCATCAGCAGCAATCCGGGCTCTCCCCTCTCGAGTGTGGCAGATATACCCATCGAAATGATAGTAGGTCCGGAATTTAT
CACAGGCAGCTCGCGCATGAAGAGCGGCACAGGGCAAAAAATGATACTGAATATGATAAGTACCACCGTCATGATAAAAC
TGGGCAGAGTAAAAGGAAACCGGATGGTAAACATGCAACTCAGCAATCGAAAACTAATAAACCGAGGAGTGCAAATGCTG
ATTGACGAATTACATATTAATAAAGCAGAAGCAAAACAATTACTGCAAGAACAGGGTTCTGTTAAAAAGGCATTGGACGC
TTACAAAACAAATAATTGTATCACTAAAAACAACTGA

Upstream 100 bases:

>100_bases
TTCAAGAAGAAGTAAAAGAAGCAGCTCTAAGACTGAATGTGTCCATCGGAAAAGTTTTAAAAAGTCCACTGGAAGGATTA
AAGGATTATCATTTCGAAGT

Downstream 100 bases:

>100_bases
AGTATGAAAAGTTGGAAACTGGAAGCCGTCATCCTTGCTATAGGCATGTTGGTGATGGGGTATTTTATCAAACAGGGATT
GGATACTTTCTCTGGTAAAG

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNFIKITEQPSIHEDLEQKSVRELLEGINEEDRKVASAVHACIPQIEKLVNEIVERMHQGGRIFYLGAGTSGRLGVLDAS
EIPPTFGMPDTCVIGIIAGGEQALRRPVENAEDDSQKGWMELQDHHITNKDILIGIAASGTTPYVIGALQKAREHGILTA
SISSNPGSPLSSVADIPIEMIVGPEFITGSSRMKSGTGQKMILNMISTTVMIKLGRVKGNRMVNMQLSNRKLINRGVQML
IDELHINKAEAKQLLQEQGSVKKALDAYKTNNCITKNN

Sequences:

>Translated_278_residues
MNFIKITEQPSIHEDLEQKSVRELLEGINEEDRKVASAVHACIPQIEKLVNEIVERMHQGGRIFYLGAGTSGRLGVLDAS
EIPPTFGMPDTCVIGIIAGGEQALRRPVENAEDDSQKGWMELQDHHITNKDILIGIAASGTTPYVIGALQKAREHGILTA
SISSNPGSPLSSVADIPIEMIVGPEFITGSSRMKSGTGQKMILNMISTTVMIKLGRVKGNRMVNMQLSNRKLINRGVQML
IDELHINKAEAKQLLQEQGSVKKALDAYKTNNCITKNN
>Mature_278_residues
MNFIKITEQPSIHEDLEQKSVRELLEGINEEDRKVASAVHACIPQIEKLVNEIVERMHQGGRIFYLGAGTSGRLGVLDAS
EIPPTFGMPDTCVIGIIAGGEQALRRPVENAEDDSQKGWMELQDHHITNKDILIGIAASGTTPYVIGALQKAREHGILTA
SISSNPGSPLSSVADIPIEMIVGPEFITGSSRMKSGTGQKMILNMISTTVMIKLGRVKGNRMVNMQLSNRKLINRGVQML
IDELHINKAEAKQLLQEQGSVKKALDAYKTNNCITKNN

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=257, Percent_Identity=45.5252918287938, Blast_Score=220, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30376; Mature: 30376

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFIKITEQPSIHEDLEQKSVRELLEGINEEDRKVASAVHACIPQIEKLVNEIVERMHQG
CCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRIFYLGAGTSGRLGVLDASEIPPTFGMPDTCVIGIIAGGEQALRRPVENAEDDSQKGWM
CEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCH
ELQDHHITNKDILIGIAASGTTPYVIGALQKAREHGILTASISSNPGSPLSSVADIPIEM
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCEEE
IVGPEFITGSSRMKSGTGQKMILNMISTTVMIKLGRVKGNRMVNMQLSNRKLINRGVQML
EECCCEECCCHHHCCCCCHHHHHHHHHHHHHHEEECCCCCEEEEEEECCHHHHHHHHHHH
IDELHINKAEAKQLLQEQGSVKKALDAYKTNNCITKNN
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNFIKITEQPSIHEDLEQKSVRELLEGINEEDRKVASAVHACIPQIEKLVNEIVERMHQG
CCCEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRIFYLGAGTSGRLGVLDASEIPPTFGMPDTCVIGIIAGGEQALRRPVENAEDDSQKGWM
CEEEEEECCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCHHHHHCCCCCCCCCCCCCCH
ELQDHHITNKDILIGIAASGTTPYVIGALQKAREHGILTASISSNPGSPLSSVADIPIEM
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHCCCEEE
IVGPEFITGSSRMKSGTGQKMILNMISTTVMIKLGRVKGNRMVNMQLSNRKLINRGVQML
EECCCEECCCHHHCCCCCHHHHHHHHHHHHHHEEECCCCCEEEEEEECCHHHHHHHHHHH
IDELHINKAEAKQLLQEQGSVKKALDAYKTNNCITKNN
HHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA