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The map label for this gene is slyD [H]

Identifier: 150005087

GI number: 150005087

Start: 3257662

End: 3258240

Strand: Reverse

Name: slyD [H]

Synonym: BVU_2552

Alternate gene names: 150005087

Gene position: 3258240-3257662 (Counterclockwise)

Preceding gene: 150005095

Following gene: 150005083

Centisome position: 63.11

GC content: 43.35

Gene sequence:

>579_bases
ATGGAAAATAAGTACATCACCGTAGCATACAAACTTTATGTAATGCAAGACGGCCAGAAAACATTGGTAGAAGAAGCAAC
TGTAGAACATCCTTTCCAGTTCATATCCGGCTTAGGAACCACACTGGAACGCTTTGAAACAGAAATAACAGCCTTGAAGA
AGGGTGATAAATTTGAATTTGTCATTCCTACCGCAGAAGCCTACGGAGAATATATGCCCGAAGGTGTGCGCACTGTATCT
AAAGATATGTTCACCATTGATGGTGTTTTTGATGAAGAACGTATCTTCCCGGGGGCTGTCATTCCCTTACAGGACAATGA
AGGCCATCACTTCTACGCTACCGTAAGCGAAGTAACCAATGACACTGTTACTGTAGATTTAAACCATCCTCATGCAGGTA
AAGATCTCACTTTTGAAGGTGAAGTAGTAGAATCCCGCACAGCCACTAATGAAGAAATTCAGGAAATGGTAAAAATGATG
AGTGGAGAAGGATGCGGCTGTGGTTGTGGTGACTGCGGAGGTGGATGCGGTGATGGTTGTAGTGATGAAAACAACTGTGG
ATGCGGACATTGCCACTAA

Upstream 100 bases:

>100_bases
TATAAACGTAATAACAAAGGATTAAGGGGAATTAATTCGTATCTTTGCCAACGGAAAACTTACGTAAGTAGTTTATATTA
CATTATTATAATAAGAAAAC

Downstream 100 bases:

>100_bases
TCCAATTTGAAAAATAATAAAACGAGAAAAGGGCGGATTTTTTGTTCCGCCCTTTTTGTTTCTCTCTATAGGATATCCGG
ATATTTCTTAATCTTTTCAG

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 192; Mature: 192

Protein sequence:

>192_residues
MENKYITVAYKLYVMQDGQKTLVEEATVEHPFQFISGLGTTLERFETEITALKKGDKFEFVIPTAEAYGEYMPEGVRTVS
KDMFTIDGVFDEERIFPGAVIPLQDNEGHHFYATVSEVTNDTVTVDLNHPHAGKDLTFEGEVVESRTATNEEIQEMVKMM
SGEGCGCGCGDCGGGCGDGCSDENNCGCGHCH

Sequences:

>Translated_192_residues
MENKYITVAYKLYVMQDGQKTLVEEATVEHPFQFISGLGTTLERFETEITALKKGDKFEFVIPTAEAYGEYMPEGVRTVS
KDMFTIDGVFDEERIFPGAVIPLQDNEGHHFYATVSEVTNDTVTVDLNHPHAGKDLTFEGEVVESRTATNEEIQEMVKMM
SGEGCGCGCGDCGGGCGDGCSDENNCGCGHCH
>Mature_192_residues
MENKYITVAYKLYVMQDGQKTLVEEATVEHPFQFISGLGTTLERFETEITALKKGDKFEFVIPTAEAYGEYMPEGVRTVS
KDMFTIDGVFDEERIFPGAVIPLQDNEGHHFYATVSEVTNDTVTVDLNHPHAGKDLTFEGEVVESRTATNEEIQEMVKMM
SGEGCGCGCGDCGGGCGDGCSDENNCGCGHCH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=34.4594594594595, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 21017; Mature: 21017

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: PS00022 EGF_1 ; PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENKYITVAYKLYVMQDGQKTLVEEATVEHPFQFISGLGTTLERFETEITALKKGDKFEF
CCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VIPTAEAYGEYMPEGVRTVSKDMFTIDGVFDEERIFPGAVIPLQDNEGHHFYATVSEVTN
EEECHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEHHHCCC
DTVTVDLNHPHAGKDLTFEGEVVESRTATNEEIQEMVKMMSGEGCGCGCGDCGGGCGDGC
CEEEEEECCCCCCCCCEECCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SDENNCGCGHCH
CCCCCCCCCCCC
>Mature Secondary Structure
MENKYITVAYKLYVMQDGQKTLVEEATVEHPFQFISGLGTTLERFETEITALKKGDKFEF
CCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VIPTAEAYGEYMPEGVRTVSKDMFTIDGVFDEERIFPGAVIPLQDNEGHHFYATVSEVTN
EEECHHHHHHHCCHHHHHHHHCEEEECCCCCCCCCCCCEEEEEECCCCCEEEEEHHHCCC
DTVTVDLNHPHAGKDLTFEGEVVESRTATNEEIQEMVKMMSGEGCGCGCGDCGGGCGDGC
CEEEEEECCCCCCCCCEECCCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
SDENNCGCGHCH
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]