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The map label for this gene is aroE [H]

Identifier: 150005076

GI number: 150005076

Start: 3243855

End: 3244595

Strand: Reverse

Name: aroE [H]

Synonym: BVU_2541

Alternate gene names: 150005076

Gene position: 3244595-3243855 (Counterclockwise)

Preceding gene: 150005077

Following gene: 150005075

Centisome position: 62.84

GC content: 40.62

Gene sequence:

>741_bases
ATGAAAAAATATGGTTTGATAGGTTATCCGTTAGGACACTCGTTCTCAAAGAACTTTTTCAATGAAAAGTTTCATTCGGA
AAACATTGATGCCGAATATGTAAACTTCGAAATCCCATCCATCAAAGAACTGCCTTCTGTGCTATTGGCTAATCCTGATT
TAGTAGGGCTCAATGTCACTATACCTTATAAAGAACAAGTCATCTCTTATTTGGACGAACTGGATAAAGATGCGGCAGCC
ATCGGAGCCGTCAATGTAATCAAAATTGTCCGCCAAAAAGGTAAGACCAGGCTGATAGGCTATAATTCCGATGTGATTGG
CTTCACTCAATCTATCGAACCCTTGCTGGAACCCCAGCACAAAAAAGCTCTGATCCTAGGAACAGGAGGTGCCTCGAAAG
CGATTGCTTACGGACTGAAAAAATTAGGTTTGGAATGCAAATTCGTATCACGGAACCTGCGTGAAGAAATGCTGACTTAC
GATCAGCTCACTCCCGAAATCATGGATGAGTATAAAGTAGTTGTCAACTGTACTCCTGTAGGTATGTATCCCCGTGCCGA
TGAATATCCCAATATTCCATACCAATATCTCACACCCAACCATTTGCTTTATGATTTGTTATATAATCCTGACACTACTC
TTTTTATGAAAAAGGGGGCAGACAAAGGGGCAATTACCAAAAACGGTTTAGAAATGCTCTTATTGCAAGCCTTTGGTGCA
TGGGATATATGGAACAAATAG

Upstream 100 bases:

>100_bases
TATCCGTAAAGCCGGATTCAATCAGGTGAGTTTCAAGCGGTTGACACTAGGTATCTGTACGCTTTATTTAGCAACGAAAT
AATTTAAAGTATAGAGTTTT

Downstream 100 bases:

>100_bases
TTAAGGTATGAAAAGAAAAAAAATGATTATTGGAACGAGTAGTATATTCGTTCTGCTTATTATAGTCCTACTTGGAGGCA
GTCAATATATGCTGAACTAT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKYGLIGYPLGHSFSKNFFNEKFHSENIDAEYVNFEIPSIKELPSVLLANPDLVGLNVTIPYKEQVISYLDELDKDAAA
IGAVNVIKIVRQKGKTRLIGYNSDVIGFTQSIEPLLEPQHKKALILGTGGASKAIAYGLKKLGLECKFVSRNLREEMLTY
DQLTPEIMDEYKVVVNCTPVGMYPRADEYPNIPYQYLTPNHLLYDLLYNPDTTLFMKKGADKGAITKNGLEMLLLQAFGA
WDIWNK

Sequences:

>Translated_246_residues
MKKYGLIGYPLGHSFSKNFFNEKFHSENIDAEYVNFEIPSIKELPSVLLANPDLVGLNVTIPYKEQVISYLDELDKDAAA
IGAVNVIKIVRQKGKTRLIGYNSDVIGFTQSIEPLLEPQHKKALILGTGGASKAIAYGLKKLGLECKFVSRNLREEMLTY
DQLTPEIMDEYKVVVNCTPVGMYPRADEYPNIPYQYLTPNHLLYDLLYNPDTTLFMKKGADKGAITKNGLEMLLLQAFGA
WDIWNK
>Mature_246_residues
MKKYGLIGYPLGHSFSKNFFNEKFHSENIDAEYVNFEIPSIKELPSVLLANPDLVGLNVTIPYKEQVISYLDELDKDAAA
IGAVNVIKIVRQKGKTRLIGYNSDVIGFTQSIEPLLEPQHKKALILGTGGASKAIAYGLKKLGLECKFVSRNLREEMLTY
DQLTPEIMDEYKVVVNCTPVGMYPRADEYPNIPYQYLTPNHLLYDLLYNPDTTLFMKKGADKGAITKNGLEMLLLQAFGA
WDIWNK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=262, Percent_Identity=29.7709923664122, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787983, Length=271, Percent_Identity=27.6752767527675, Blast_Score=89, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320332, Length=270, Percent_Identity=26.2962962962963, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 27731; Mature: 27731

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKYGLIGYPLGHSFSKNFFNEKFHSENIDAEYVNFEIPSIKELPSVLLANPDLVGLNVT
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEE
IPYKEQVISYLDELDKDAAAIGAVNVIKIVRQKGKTRLIGYNSDVIGFTQSIEPLLEPQH
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCC
KKALILGTGGASKAIAYGLKKLGLECKFVSRNLREEMLTYDQLTPEIMDEYKVVVNCTPV
CCEEEEECCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCHHHHHCEEEEEEEECC
GMYPRADEYPNIPYQYLTPNHLLYDLLYNPDTTLFMKKGADKGAITKNGLEMLLLQAFGA
CCCCCCCCCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
WDIWNK
CCCCCC
>Mature Secondary Structure
MKKYGLIGYPLGHSFSKNFFNEKFHSENIDAEYVNFEIPSIKELPSVLLANPDLVGLNVT
CCCCCEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEEEE
IPYKEQVISYLDELDKDAAAIGAVNVIKIVRQKGKTRLIGYNSDVIGFTQSIEPLLEPQH
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCC
KKALILGTGGASKAIAYGLKKLGLECKFVSRNLREEMLTYDQLTPEIMDEYKVVVNCTPV
CCEEEEECCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHCCHHHHHCEEEEEEEECC
GMYPRADEYPNIPYQYLTPNHLLYDLLYNPDTTLFMKKGADKGAITKNGLEMLLLQAFGA
CCCCCCCCCCCCCEEEECCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHCCC
WDIWNK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA