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The map label for this gene is aroC

Identifier: 150005072

GI number: 150005072

Start: 3240077

End: 3241153

Strand: Reverse

Name: aroC

Synonym: BVU_2537

Alternate gene names: 150005072

Gene position: 3241153-3240077 (Counterclockwise)

Preceding gene: 150005073

Following gene: 150005071

Centisome position: 62.77

GC content: 45.59

Gene sequence:

>1077_bases
ATGTTCAATTCATTTGGTAATATTTTCCGGTTAACCAGTTTCGGTGAATCCCATGGACCGGGAGTAGGCGGCGTCATTGA
CGGCTTCCCTGCCGGTATTAAGATTGATATGGATTTCGTTCAGCAGGAACTGAACCGCCGCCGTCCCGGACAGTCATTAC
TTACCACCAGCCGCAAGGAGCCTGATACAGTGGAATTCCTTTCAGGTATATTCGAAGGCAAGTCCACCGGCTGCCCCATC
GGATTTGTGGTATGGAACAAGAACCAACATTCAAACGACTACGAGAATATCAAGAATCTGTTCCGCCCTTCACACGCAGA
TTATACTTATATGCAAAAATACGGAATCCGTGACTACCGTGGCGGGGGACGTTCATCAGCACGAGAAACCATTTCACGTG
TAGTAGCAGGAGCTTTAGCCAAATTGGCATTGAAACAACTAGGAATCAGTGTCACAGCTTATACCTCACAGGTAGGACCT
GTCAAACTTGATAAAGATTACAAAAGCTATAACCTCGACTTGATAGAAACAAACGATGTGCGTTGTCCCGATCCGGAAAA
AGCCAAGGAAATGGCAGAACTTATCTGGAAAATCAAAGGAGAAGGCGATACAATAGGCGGGGTAGTGAGTTGCGTCATCA
AAGGATGCCCTATCGGACTAGGGCAACCCGTATTCGGTAAGTTACATGCCGCACTAGGAAATGCCATGTTAAGTATCAAT
GCCGTAAAAGGTTTCTCTTACGGACAAGGTTTTGACTCCATGGAGCTAAAAGGCAGTGAGCAGAATGATGTATTTTATAA
TAATAACGGAAGAGTAGAAACAAAAAGTAATTATTCCGGAGGAATACAAGGAGGCATCAGCAACGGGCAAGACATTTACT
TCCGTGTGGCATTCAAGCCAGTTGCCACAATTCTGATGGAGCAACATACAGTAAATATCAACGGCACAGACACGACCATG
AAAGCCAAAGGGCGTCATGATGCCTGCGTACTGCCGCGTGCCGTCCCCATTGTAGAAGCCATGGCTGCCATGACCATTTT
GGATTATTATCTGATAGACAGAACTACACAACTATAA

Upstream 100 bases:

>100_bases
CCCATTTTTATCCATTCTGCTAATTTTTCAGCAACAATCAAGTATATTATCCCTAAAATCATTATCTTTACGGAAAGAAA
CTTTTAAAACTACAAGCAAT

Downstream 100 bases:

>100_bases
GAATCATTCAATTATGGAAATAAAACAATACATTAAAGAAAATGAAGCACGCTTCATGGAGGAACTTTTCAGCCTCATCC
GTATTCCCAGTATCAGTGCT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MFNSFGNIFRLTSFGESHGPGVGGVIDGFPAGIKIDMDFVQQELNRRRPGQSLLTTSRKEPDTVEFLSGIFEGKSTGCPI
GFVVWNKNQHSNDYENIKNLFRPSHADYTYMQKYGIRDYRGGGRSSARETISRVVAGALAKLALKQLGISVTAYTSQVGP
VKLDKDYKSYNLDLIETNDVRCPDPEKAKEMAELIWKIKGEGDTIGGVVSCVIKGCPIGLGQPVFGKLHAALGNAMLSIN
AVKGFSYGQGFDSMELKGSEQNDVFYNNNGRVETKSNYSGGIQGGISNGQDIYFRVAFKPVATILMEQHTVNINGTDTTM
KAKGRHDACVLPRAVPIVEAMAAMTILDYYLIDRTTQL

Sequences:

>Translated_358_residues
MFNSFGNIFRLTSFGESHGPGVGGVIDGFPAGIKIDMDFVQQELNRRRPGQSLLTTSRKEPDTVEFLSGIFEGKSTGCPI
GFVVWNKNQHSNDYENIKNLFRPSHADYTYMQKYGIRDYRGGGRSSARETISRVVAGALAKLALKQLGISVTAYTSQVGP
VKLDKDYKSYNLDLIETNDVRCPDPEKAKEMAELIWKIKGEGDTIGGVVSCVIKGCPIGLGQPVFGKLHAALGNAMLSIN
AVKGFSYGQGFDSMELKGSEQNDVFYNNNGRVETKSNYSGGIQGGISNGQDIYFRVAFKPVATILMEQHTVNINGTDTTM
KAKGRHDACVLPRAVPIVEAMAAMTILDYYLIDRTTQL
>Mature_358_residues
MFNSFGNIFRLTSFGESHGPGVGGVIDGFPAGIKIDMDFVQQELNRRRPGQSLLTTSRKEPDTVEFLSGIFEGKSTGCPI
GFVVWNKNQHSNDYENIKNLFRPSHADYTYMQKYGIRDYRGGGRSSARETISRVVAGALAKLALKQLGISVTAYTSQVGP
VKLDKDYKSYNLDLIETNDVRCPDPEKAKEMAELIWKIKGEGDTIGGVVSCVIKGCPIGLGQPVFGKLHAALGNAMLSIN
AVKGFSYGQGFDSMELKGSEQNDVFYNNNGRVETKSNYSGGIQGGISNGQDIYFRVAFKPVATILMEQHTVNINGTDTTM
KAKGRHDACVLPRAVPIVEAMAAMTILDYYLIDRTTQL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=354, Percent_Identity=49.1525423728814, Blast_Score=323, Evalue=9e-90,
Organism=Saccharomyces cerevisiae, GI6321290, Length=366, Percent_Identity=46.7213114754098, Blast_Score=337, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_BACV8 (A6L3D0)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299816.1
- ProteinModelPortal:   A6L3D0
- SMR:   A6L3D0
- STRING:   A6L3D0
- GeneID:   5303501
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2537
- NMPDR:   fig|435590.6.peg.2379
- eggNOG:   COG0082
- HOGENOM:   HBG292336
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39167; Mature: 39167

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNSFGNIFRLTSFGESHGPGVGGVIDGFPAGIKIDMDFVQQELNRRRPGQSLLTTSRKE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHCCCCC
PDTVEFLSGIFEGKSTGCPIGFVVWNKNQHSNDYENIKNLFRPSHADYTYMQKYGIRDYR
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCC
GGGRSSARETISRVVAGALAKLALKQLGISVTAYTSQVGPVKLDKDYKSYNLDLIETNDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCEEEEECCCC
RCPDPEKAKEMAELIWKIKGEGDTIGGVVSCVIKGCPIGLGQPVFGKLHAALGNAMLSIN
CCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
AVKGFSYGQGFDSMELKGSEQNDVFYNNNGRVETKSNYSGGIQGGISNGQDIYFRVAFKP
EECCCCCCCCCCCCEECCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEHHH
VATILMEQHTVNINGTDTTMKAKGRHDACVLPRAVPIVEAMAAMTILDYYLIDRTTQL
HHHHHHHHEEEEECCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFNSFGNIFRLTSFGESHGPGVGGVIDGFPAGIKIDMDFVQQELNRRRPGQSLLTTSRKE
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHCCCCC
PDTVEFLSGIFEGKSTGCPIGFVVWNKNQHSNDYENIKNLFRPSHADYTYMQKYGIRDYR
CCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCC
GGGRSSARETISRVVAGALAKLALKQLGISVTAYTSQVGPVKLDKDYKSYNLDLIETNDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCEEEEECCCC
RCPDPEKAKEMAELIWKIKGEGDTIGGVVSCVIKGCPIGLGQPVFGKLHAALGNAMLSIN
CCCCHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEE
AVKGFSYGQGFDSMELKGSEQNDVFYNNNGRVETKSNYSGGIQGGISNGQDIYFRVAFKP
EECCCCCCCCCCCCEECCCCCCCEEECCCCEEEECCCCCCCCCCCCCCCCEEEEEEEHHH
VATILMEQHTVNINGTDTTMKAKGRHDACVLPRAVPIVEAMAAMTILDYYLIDRTTQL
HHHHHHHHEEEEECCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA