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The map label for this gene is yqjC [H]

Identifier: 150005027

GI number: 150005027

Start: 3194310

End: 3194723

Strand: Reverse

Name: yqjC [H]

Synonym: BVU_2492

Alternate gene names: 150005027

Gene position: 3194723-3194310 (Counterclockwise)

Preceding gene: 150005028

Following gene: 150005026

Centisome position: 61.87

GC content: 43.24

Gene sequence:

>414_bases
ATGAAAATCTCACACATTGAACACCTGGGCATTGCCGTAAAGAGCATTGAAGAGGCCCTGCCGTATTATGAAAACGTATT
AGGTCTGAAATGCTACAATATCGAAACAGTAGAGGATCAGAAAGTTAAAACCGCTTTTCTGAAAGTAGGTGATGTTAAAA
TAGAACTGCTGGAACCTACAAGCCCCGAAAGCACTATCGCAAAGTTCATTGAAAAAAATAATGGCAACGGTGGTATGCAT
CATTTGGCTTTTGCAGTGGAAGATGGTGTGGCAAATGCGTTAGCCGAAGCTGAAACCACCGGCATCCGTCTCATTGACAA
AGCTCCGCGTAAAGGTGCCGAAGGTTTGCAAATTGCTTTTTTACATCCCAAATCAACTTTGGGCGTCCTGACCGAGCTTT
GCGAAAAACCATAA

Upstream 100 bases:

>100_bases
AATTGAAGAAATATTTCTTTATTTAACTCGAAATTACTTTCTTTGTGCAGTTTTATCTGAAAACTTGAGTATAAAACCAA
ACTATTAAAATTATAAGATC

Downstream 100 bases:

>100_bases
AACACGAGATCTGACTATTCACGATTGAAGTCAGTATATTTAGTCTGGTTCAAGCGTAAATAGAATTATTTTTTAATCGT
AAATTGTAAAATCATAAGTA

Product: lactoyl gluthatione lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVKTAFLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMH
HLAFAVEDGVANALAEAETTGIRLIDKAPRKGAEGLQIAFLHPKSTLGVLTELCEKP

Sequences:

>Translated_137_residues
MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVKTAFLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMH
HLAFAVEDGVANALAEAETTGIRLIDKAPRKGAEGLQIAFLHPKSTLGVLTELCEKP
>Mature_137_residues
MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVKTAFLKVGDVKIELLEPTSPESTIAKFIEKNNGNGGMH
HLAFAVEDGVANALAEAETTGIRLIDKAPRKGAEGLQIAFLHPKSTLGVLTELCEKP

Specific function: Unknown

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyoxalase I family [H]

Homologues:

Organism=Homo sapiens, GI188035928, Length=131, Percent_Identity=35.8778625954198, Blast_Score=86, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17506387, Length=128, Percent_Identity=36.71875, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR018146
- InterPro:   IPR017515 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14909; Mature: 14909

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVKTAFLKVGDVKIELLEPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHEEECCEEEEEECCC
SPESTIAKFIEKNNGNGGMHHLAFAVEDGVANALAEAETTGIRLIDKAPRKGAEGLQIAF
CCHHHHHHHHHCCCCCCCHHHEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEE
LHPKSTLGVLTELCEKP
ECCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVKTAFLKVGDVKIELLEPT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHEEECCEEEEEECCC
SPESTIAKFIEKNNGNGGMHHLAFAVEDGVANALAEAETTGIRLIDKAPRKGAEGLQIAF
CCHHHHHHHHHCCCCCCCHHHEEEEHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEE
LHPKSTLGVLTELCEKP
ECCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]