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The map label for this gene is cdr [H]

Identifier: 150004959

GI number: 150004959

Start: 3108448

End: 3110949

Strand: Direct

Name: cdr [H]

Synonym: BVU_2422

Alternate gene names: 150004959

Gene position: 3108448-3110949 (Clockwise)

Preceding gene: 150004950

Following gene: 150004960

Centisome position: 60.2

GC content: 46.8

Gene sequence:

>2502_bases
ATGAAGTATATAGTAATAGGAGGCGTAGCAGGAGGTGCAACTGCTGCCGCACGTATCAGAAGAAACACGGAACAGGCGGA
AATCATTTTGTTCGAGAAGGGAGAATACATTTCGTATGCCAATTGTGGTCTGCCTTATTATATAGGAGGTGTGATTGCGG
AGCGGGAAAAATTGTTTGTACAGACTCCGGAGGCTTTCGGGAAACGTTTTAACATAGATGTGCGTACCCGGTCCGAGGTA
ATAGCCATCCATTCTGCCGATAAGACAGTGGATATTCGTACTTCCGACGGGAAAACTTATACGGAGAGTTATGACAAATT
ATTGCTTTCTCCGGGTGCGTCGCCTGTTCGTCCTCCCTTGCCGGGCATTGACAATGAAGGAATTTTTACCCTACGTAATG
TGAATGATACCGATGCTATCAAGAGTTACTTGCAGCAGCATAAGGTGAAACGGGCGGTAATCATCGGGGCCGGATTCATC
GGGTTGGAGATGGCGGAGAATCTGCAGGAAGCCGGTGCGGAAGTGGCGGTTGTAGAGATGGCAAATCAAGTCATGGCTCC
TATTGATTTCTCTATGGCTTCTTTGGTGCACGAGCATTTGTTGCAGAAAGGAGTGCATCTCTACCTGGAAAAGGCGGTGG
CTTCTTTCGAGCGCACGGTCAACGGACTGGAGGTTATTTTTAAATCGGGCGAAAGGCTGCCTGCCGATATGGTGTTGTTA
TCCATCGGGGTACGTCCCAATACCTCATTGGTGACAGAGGCCGGACTGGAGATAGGGGAGATGCGCGGCATTAAGGTGAA
CGATTACTTGCAGACTTCCGACGAGTATATTTATGCGGTGGGCGACGCTATCGAGTTCCGTCATCCGCTGACTGATAGAC
CGTGGTTGAATTATCTGGCTGGTCCGGCCAACCGTCAGGCGCGTATTGTGGCAGATAACATGGTTTTTGGAAATAAGGTT
ACATACGAAGGGGCTGTCGGTACTTCCATTGCCAAAATTTTTGATATGACTGTCGCTGCTTCAGGCCTTCCGGCAAAGCG
GTTGAAACAGGCAGGCATTGATTATTTGTCGGCAACCATCCATTCCGGTTCCCATGCGGGATATTATCCCGATGCTTTAC
AGATGTCCATTAAAATAACCTTCTCTCCTGTGAACGGGAAATTACTTGGAGCGCAGATTGTGGGGTATAATGGAGTGGAC
AAACGTATTGACGAATTCTCGCAAGTGATTAAGCATAACGGAACTGTATATGACTTGATGGCTTTGGAGCAGGCATACGC
TCCTCCTTTCTCTTCGGCTAAAGATCCTGTAGCAGTAGCCGGATATGTAGCCGGAAATATACTGAGCGGAAAGATGAAGC
CTCTTTATTGGCGCGAGTTGCAGGCTGCCGATTTGAGTAAAGTTACGTTGGTTGATGTCCGTACTCCCGATGAATTTGCA
CTCGGTGCTTTGAAGGGGGCTGTCAATATTCCTTTGGATGATATGCGCGAAAGGATGAAAGAGATTCCTCAGGATAAGCC
GGTCTATTTGTATTGTGGAGTGGGGTTGAGAGGGTATCTGGCTTCTAATATATTGTTACAGAATGGCTTTGGGGAAGTAA
GGAATTTAATAGGAGGTTTGAAACTGTATAAAGCGGCAACGGCTCCTCTGCCCAAGCCGAAGGAGTTCTCAAATTCCGGA
TCTTCAAGTTCTGATTCTTCAAAAGTTGATCATTCTGAACACAGTAAAGATTCTGCTGAAGCTTATACTATTGCCTCTTC
CGTCATTCCTTCTATGAAAGCAATAAAAGTGGATGCTTGTGGCATATCTTGTCCCGGTCCTATCATGAAGCTGAAGAAGA
GTATGGAAGAACTGGCGGACGGCGAACGTCTGGAGATTGTCGCTACGGATGCCGGTTTCCCCCGCGATGCCGAAGCATGG
TGCCAGACTACCGGGAACCGTTTTGTCTCAGTAAAGTCAGGAGCAGGAAAGTATGAGGTAATTGTTGAGAAAAGTACTCC
GCAATCTTCTTCCTCGGAGGTTTGCCGGGAGGATAAAGGGAAAACTTTTATTCTGTTCAGTGACAACCTGGACAAAGTTT
TAGCTACTTTTGTACTCGCAAACGGTGCGGCGGCTACGGGAAAGAAGGTGATCATCTTCTTTACTTTCTGGGGGCTGAAT
GCTATCAAAAGATTGGACAAGCCTGCGGTGAAGAAAGATATCTGGGGGAAGATGTTCGGCATGATGCTGCCTTCCAGTTC
TTTAAAGTTGAGATTGTCTAAAATGAATATGGGTGGAATGGGAGCCAGGATGATGCGATATATCATGAATAAGAAAAATA
TCGACTCACTGGAATCTCTGCGTACTCAAGCCATTCAGAACGGAGTGGAATTTATAGCTTGCCAGATGTCAATGGATGTA
ATGGGTGTGAAACGTGAGGAATTGCTGGATCATGTGACTATTGGCGGAGTGGCAACCTATATGAACCGTGCCGAACAGGC
GAATGTAAACTTGTTTATTTAA

Upstream 100 bases:

>100_bases
ATAATATTTTCCATAGGAAACTTTTTATTATAAGAAATATCATGTATGTTTGCATAAAGTTTCCATTGGAAAATATTAAA
TCAAATAAAATAGTTCGATT

Downstream 100 bases:

>100_bases
ATTTGCATGGAGAAAATAAAATCAATATGTGTCATGAGAGAGTTGTTCAAGGCTCTCTCTGAACTTGAAACCCGCTTGAT
GGAACAATATGGAGTGTCAT

Product: pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: CoA-disulfide reductase; CoADR [H]

Number of amino acids: Translated: 833; Mature: 833

Protein sequence:

>833_residues
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFVQTPEAFGKRFNIDVRTRSEV
IAIHSADKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPLPGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFI
GLEMAENLQEAGAEVAVVEMANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVIFKSGERLPADMVLL
SIGVRPNTSLVTEAGLEIGEMRGIKVNDYLQTSDEYIYAVGDAIEFRHPLTDRPWLNYLAGPANRQARIVADNMVFGNKV
TYEGAVGTSIAKIFDMTVAASGLPAKRLKQAGIDYLSATIHSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVD
KRIDEFSQVIKHNGTVYDLMALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFA
LGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVRNLIGGLKLYKAATAPLPKPKEFSNSG
SSSSDSSKVDHSEHSKDSAEAYTIASSVIPSMKAIKVDACGISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAW
CQTTGNRFVSVKSGAGKYEVIVEKSTPQSSSSEVCREDKGKTFILFSDNLDKVLATFVLANGAAATGKKVIIFFTFWGLN
AIKRLDKPAVKKDIWGKMFGMMLPSSSLKLRLSKMNMGGMGARMMRYIMNKKNIDSLESLRTQAIQNGVEFIACQMSMDV
MGVKREELLDHVTIGGVATYMNRAEQANVNLFI

Sequences:

>Translated_833_residues
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFVQTPEAFGKRFNIDVRTRSEV
IAIHSADKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPLPGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFI
GLEMAENLQEAGAEVAVVEMANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVIFKSGERLPADMVLL
SIGVRPNTSLVTEAGLEIGEMRGIKVNDYLQTSDEYIYAVGDAIEFRHPLTDRPWLNYLAGPANRQARIVADNMVFGNKV
TYEGAVGTSIAKIFDMTVAASGLPAKRLKQAGIDYLSATIHSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVD
KRIDEFSQVIKHNGTVYDLMALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFA
LGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVRNLIGGLKLYKAATAPLPKPKEFSNSG
SSSSDSSKVDHSEHSKDSAEAYTIASSVIPSMKAIKVDACGISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAW
CQTTGNRFVSVKSGAGKYEVIVEKSTPQSSSSEVCREDKGKTFILFSDNLDKVLATFVLANGAAATGKKVIIFFTFWGLN
AIKRLDKPAVKKDIWGKMFGMMLPSSSLKLRLSKMNMGGMGARMMRYIMNKKNIDSLESLRTQAIQNGVEFIACQMSMDV
MGVKREELLDHVTIGGVATYMNRAEQANVNLFI
>Mature_833_residues
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFVQTPEAFGKRFNIDVRTRSEV
IAIHSADKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPLPGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFI
GLEMAENLQEAGAEVAVVEMANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVIFKSGERLPADMVLL
SIGVRPNTSLVTEAGLEIGEMRGIKVNDYLQTSDEYIYAVGDAIEFRHPLTDRPWLNYLAGPANRQARIVADNMVFGNKV
TYEGAVGTSIAKIFDMTVAASGLPAKRLKQAGIDYLSATIHSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVD
KRIDEFSQVIKHNGTVYDLMALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFA
LGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVRNLIGGLKLYKAATAPLPKPKEFSNSG
SSSSDSSKVDHSEHSKDSAEAYTIASSVIPSMKAIKVDACGISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAW
CQTTGNRFVSVKSGAGKYEVIVEKSTPQSSSSEVCREDKGKTFILFSDNLDKVLATFVLANGAAATGKKVIIFFTFWGLN
AIKRLDKPAVKKDIWGKMFGMMLPSSSLKLRLSKMNMGGMGARMMRYIMNKKNIDSLESLRTQAIQNGVEFIACQMSMDV
MGVKREELLDHVTIGGVATYMNRAEQANVNLFI

Specific function: Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI21389617, Length=328, Percent_Identity=27.7439024390244, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI65787454, Length=328, Percent_Identity=27.7439024390244, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI226437568, Length=328, Percent_Identity=27.7439024390244, Blast_Score=107, Evalue=5e-23,
Organism=Homo sapiens, GI50301238, Length=269, Percent_Identity=27.8810408921933, Blast_Score=68, Evalue=4e-11,
Organism=Escherichia coli, GI1789065, Length=264, Percent_Identity=30.6818181818182, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI1789765, Length=374, Percent_Identity=28.3422459893048, Blast_Score=106, Evalue=8e-24,
Organism=Escherichia coli, GI1788892, Length=287, Percent_Identity=29.616724738676, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1786307, Length=318, Percent_Identity=28.6163522012579, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI87082354, Length=238, Percent_Identity=27.7310924369748, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17559934, Length=301, Percent_Identity=25.5813953488372, Blast_Score=93, Evalue=7e-19,
Organism=Drosophila melanogaster, GI281359715, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281359713, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639250, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI18543267, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639252, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639257, Length=325, Percent_Identity=28, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24585130, Length=326, Percent_Identity=24.2331288343558, Blast_Score=83, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21358499, Length=207, Percent_Identity=34.2995169082126, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017758
- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: =1.8.1.14 [H]

Molecular weight: Translated: 90806; Mature: 90806

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50206 RHODANESE_3 ; PS01148 UPF0033

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFV
CEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHCCCCEEE
QTPEAFGKRFNIDVRTRSEVIAIHSADKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPL
ECHHHHCCEEEEEEECCCEEEEEEECCCEEEEEECCCCCHHHHHHHEEECCCCCCCCCCC
PGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFIGLEMAENLQEAGAEVAVVEM
CCCCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCEEEHHH
ANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVIFKSGERLPADMVLL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
SIGVRPNTSLVTEAGLEIGEMRGIKVNDYLQTSDEYIYAVGDAIEFRHPLTDRPWLNYLA
EECCCCCCCHHHHCCCCHHHCCCEEECCCCCCCCCEEEEECCHHCCCCCCCCCCHHHHHC
GPANRQARIVADNMVFGNKVTYEGAVGTSIAKIFDMTVAASGLPAKRLKQAGIDYLSATI
CCCCCCEEEEEECEEECCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHH
HSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVDKRIDEFSQVIKHNGTVYDLM
CCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEHH
ALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFA
HHHHHCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
LGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVRNLIGGL
HHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHEECCHHHHHHHHHHH
KLYKAATAPLPKPKEFSNSGSSSSDSSKVDHSEHSKDSAEAYTIASSVIPSMKAIKVDAC
HHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAWCQTTGNRFVSVKSGAGKYEV
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCEEE
IVEKSTPQSSSSEVCREDKGKTFILFSDNLDKVLATFVLANGAAATGKKVIIFFTFWGLN
EEECCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHH
AIKRLDKPAVKKDIWGKMFGMMLPSSSLKLRLSKMNMGGMGARMMRYIMNKKNIDSLESL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHH
RTQAIQNGVEFIACQMSMDVMGVKREELLDHVTIGGVATYMNRAEQANVNLFI
HHHHHHCCHHEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure
MKYIVIGGVAGGATAAARIRRNTEQAEIILFEKGEYISYANCGLPYYIGGVIAEREKLFV
CEEEEEECCCCCHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCHHHHHHHHCCCCEEE
QTPEAFGKRFNIDVRTRSEVIAIHSADKTVDIRTSDGKTYTESYDKLLLSPGASPVRPPL
ECHHHHCCEEEEEEECCCEEEEEEECCCEEEEEECCCCCHHHHHHHEEECCCCCCCCCCC
PGIDNEGIFTLRNVNDTDAIKSYLQQHKVKRAVIIGAGFIGLEMAENLQEAGAEVAVVEM
CCCCCCCEEEECCCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCEEEHHH
ANQVMAPIDFSMASLVHEHLLQKGVHLYLEKAVASFERTVNGLEVIFKSGERLPADMVLL
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
SIGVRPNTSLVTEAGLEIGEMRGIKVNDYLQTSDEYIYAVGDAIEFRHPLTDRPWLNYLA
EECCCCCCCHHHHCCCCHHHCCCEEECCCCCCCCCEEEEECCHHCCCCCCCCCCHHHHHC
GPANRQARIVADNMVFGNKVTYEGAVGTSIAKIFDMTVAASGLPAKRLKQAGIDYLSATI
CCCCCCEEEEEECEEECCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHH
HSGSHAGYYPDALQMSIKITFSPVNGKLLGAQIVGYNGVDKRIDEFSQVIKHNGTVYDLM
CCCCCCCCCCCCEEEEEEEEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCEEEHH
ALEQAYAPPFSSAKDPVAVAGYVAGNILSGKMKPLYWRELQAADLSKVTLVDVRTPDEFA
HHHHHCCCCCCCCCCCEEEEHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCHHH
LGALKGAVNIPLDDMRERMKEIPQDKPVYLYCGVGLRGYLASNILLQNGFGEVRNLIGGL
HHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHEECCHHHHHHHHHHH
KLYKAATAPLPKPKEFSNSGSSSSDSSKVDHSEHSKDSAEAYTIASSVIPSMKAIKVDAC
HHHHHHCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
GISCPGPIMKLKKSMEELADGERLEIVATDAGFPRDAEAWCQTTGNRFVSVKSGAGKYEV
CCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHCCCCEEEEEECCCCCEEE
IVEKSTPQSSSSEVCREDKGKTFILFSDNLDKVLATFVLANGAAATGKKVIIFFTFWGLN
EEECCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHH
AIKRLDKPAVKKDIWGKMFGMMLPSSSLKLRLSKMNMGGMGARMMRYIMNKKNIDSLESL
HHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHH
RTQAIQNGVEFIACQMSMDVMGVKREELLDHVTIGGVATYMNRAEQANVNLFI
HHHHHHCCHHEEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA