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The map label for this gene is rlmH

Identifier: 150004911

GI number: 150004911

Start: 3052577

End: 3053050

Strand: Reverse

Name: rlmH

Synonym: BVU_2374

Alternate gene names: 150004911

Gene position: 3053050-3052577 (Counterclockwise)

Preceding gene: 150004914

Following gene: 150004908

Centisome position: 59.13

GC content: 39.24

Gene sequence:

>474_bases
ATGAAATTTACATTATTAGTAGTAGGACGCACTGTCGAAAAACATTATATCACCGCTATCAATGATTATGTGGAACGTAC
CAAGCACTTCATTTCTTTCGATATGGAAGTCATCCCCGAACTCAAGAACACCAAAAACCTGAGTATGGAGCAACAAAAAG
AGAAGGAAGGAGAACTAATTCTGAAAGCTTTGTTGCCGGGCGATGTAGTGGTTTTATTGGATGAACATGGAAAAGAATTC
CGTTCCGTAGAATTTGCCAACTGGATAGAACGCAAAATGCACACTGTAAACAAACGGTTAGTATTCATCATTGGGGGACC
ATACGGATTTGCACCCAAAATATATGATGCAGCCCAAGAAAAGATCTCATTATCCAAGATGACCTTCTCACATCAAATGA
TACGCCTTATTTTCGTAGAACAGCTATACCGGGCGATGACTATATTGAATAACGGTCCTTATCATCATGAATAG

Upstream 100 bases:

>100_bases
TTTACTACTAATTCGTCCATAATGTTATCGTTTTTTTATGAATTGATAGGCAAAGGTAGAGATTTTCCGTATTTTTGCAA
AGTAAACCAGAAAAGAACGT

Downstream 100 bases:

>100_bases
AAATATATAGCGGTTAGTGATTAACACCTGCGGCATAATAGCGCAGTCCATTCATCACTAACCACTAATTCTCTCCCTAT
TTTCCAATTTCAAAGTCCAC

Product: rRNA large subunit methyltransferase

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MKFTLLVVGRTVEKHYITAINDYVERTKHFISFDMEVIPELKNTKNLSMEQQKEKEGELILKALLPGDVVVLLDEHGKEF
RSVEFANWIERKMHTVNKRLVFIIGGPYGFAPKIYDAAQEKISLSKMTFSHQMIRLIFVEQLYRAMTILNNGPYHHE

Sequences:

>Translated_157_residues
MKFTLLVVGRTVEKHYITAINDYVERTKHFISFDMEVIPELKNTKNLSMEQQKEKEGELILKALLPGDVVVLLDEHGKEF
RSVEFANWIERKMHTVNKRLVFIIGGPYGFAPKIYDAAQEKISLSKMTFSHQMIRLIFVEQLYRAMTILNNGPYHHE
>Mature_157_residues
MKFTLLVVGRTVEKHYITAINDYVERTKHFISFDMEVIPELKNTKNLSMEQQKEKEGELILKALLPGDVVVLLDEHGKEF
RSVEFANWIERKMHTVNKRLVFIIGGPYGFAPKIYDAAQEKISLSKMTFSHQMIRLIFVEQLYRAMTILNNGPYHHE

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=157, Percent_Identity=33.7579617834395, Blast_Score=93, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_BACV8 (A6L2W9)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299655.1
- ProteinModelPortal:   A6L2W9
- SMR:   A6L2W9
- STRING:   A6L2W9
- GeneID:   5303338
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2374
- NMPDR:   fig|435590.6.peg.2229
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- ProtClustDB:   PRK00103
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 18355; Mature: 18355

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTLLVVGRTVEKHYITAINDYVERTKHFISFDMEVIPELKNTKNLSMEQQKEKEGELI
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHEE
LKALLPGDVVVLLDEHGKEFRSVEFANWIERKMHTVNKRLVFIIGGPYGFAPKIYDAAQE
HEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
KISLSKMTFSHQMIRLIFVEQLYRAMTILNNGPYHHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKFTLLVVGRTVEKHYITAINDYVERTKHFISFDMEVIPELKNTKNLSMEQQKEKEGELI
CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHEE
LKALLPGDVVVLLDEHGKEFRSVEFANWIERKMHTVNKRLVFIIGGPYGFAPKIYDAAQE
HEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHH
KISLSKMTFSHQMIRLIFVEQLYRAMTILNNGPYHHE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA