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The map label for this gene is mltF [H]

Identifier: 150004894

GI number: 150004894

Start: 3037272

End: 3038651

Strand: Reverse

Name: mltF [H]

Synonym: BVU_2357

Alternate gene names: 150004894

Gene position: 3038651-3037272 (Counterclockwise)

Preceding gene: 150004895

Following gene: 150004893

Centisome position: 58.85

GC content: 42.68

Gene sequence:

>1380_bases
ATGAAAAATGTCTGGCTATTAGTTCTTGCCTGTATATGCATGACAGCGTGCCGTAACCGGCAACAATCTGCCGAAGTGAC
AAATTATGATTTGCCGCAAATAAAAGACAGCGGAGAATTAGTAGTCCTGACACTGAACAGTTCCACTTCTTATTTCGACT
ATCGGGGCGAGCCTATGGGATTCCAGTATGAGCTGGCCGATCAGTTTGCCCGTTCATTGGACGTAAAACTGAAAATAAAA
GTAGCACAGAATGCACGTGACCTGGTTCATAAACTATTACAAGGAGAAGGAGACCTGATAGCCTATAATCTGCCTGTCAC
CAAAGAGTTCAAAGACAGTGTAGAGTTTTGCGGGGAAGATATCATCACCCATCAGGTATTGGTACAACGTAATACTCAAA
AAAAGAAGAAAGCACTGAATAATGTAACAGAATTAATCGGGAAAGAGGTCTATGTAAAACCAGGAAAGTATCTGGAACGT
CTCATCAATCTGGATAAAGAACTGGGTGGCGGTATATTGATACACGAAGTCGATAATGACAGCATCACCACCGAGGATTT
AATCATGCAGGTTTCCAATGGTGAGATAGATTATGCCATCTGTGATAACGACCTTGCCAAATTAAACAAGACTTATTACC
CCAATCTGAATATTGACCTGGCTGTCAGTTTTGACCAACGTGCCTCATGGGCCGTACGTAAGACCTCACCGCTACTAGGT
GAAGCTGCTACTAAATGGCATCAGGAAAATATGACTTCTCCTGCCTATCAGGCCAGTAGCAAGCGTTATTTTGAAATAAG
CAAACGGACACCTCACGGTTCCATCTTGTCCATCAAAGACGGAAAGATTTCACACTTCGACACTCTATTCAAGAAATATG
CCAAAGATATAGATTGGGATTGGCGTATTTTAGCTTCCCTGGCCTATACGGAATCAAACTTTGATACAACAGCCGTATCA
TGGGCAGGCGCGAAAGGATTAATGCAGCTCATGCCCCGGACGGCGCGTGCTATGGGAGTTCCTCCCGGTAAAGAACAGAA
TCCGGAAGAGAGTATAAAGGCCGCCGTGAAATATATTGCTGCCACTTCCCGTTCTTTCAACGCAATAAAAGATGAAAACG
AACGGATGAAATTTGTCTTGGCGGCTTATAACGCCGGAATAGGACACGTACTGGATGCCATGGCACTGGCTGAAAAATAC
GGCAAGAATAAATATGTATGGAACAACAGCGTAGATAACTATATTCTGCTTAAAAGTAATGAAGAATATTTCAATGATCC
GGTTTGTAAGAATGGATACTTCCGAGGGGTGGAAACCTACAATTTCGTTAAGGAAGTAATGAACAGAGGGGAAGTGTATA
AAAAGAAAATCAAAGACTGA

Upstream 100 bases:

>100_bases
AGCCTACCAAGCAATATGCCGATATTATTATCCCCAATGGAGGCAACAACCAAAAGGCCATTGAAATCCTTAAACTATAT
ATTGAAAAGATTTTAGGAAG

Downstream 100 bases:

>100_bases
CAGCCACTCCTTTTATTATTTCAGGTGGACTTTAAAAAACACTCCGCCGGAAAAGTAACGGCAGCGGTTGAACTCTATCA
CTGCATTGATATAATCTTTC

Product: glycoside hydrolase family protein

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKNVWLLVLACICMTACRNRQQSAEVTNYDLPQIKDSGELVVLTLNSSTSYFDYRGEPMGFQYELADQFARSLDVKLKIK
VAQNARDLVHKLLQGEGDLIAYNLPVTKEFKDSVEFCGEDIITHQVLVQRNTQKKKKALNNVTELIGKEVYVKPGKYLER
LINLDKELGGGILIHEVDNDSITTEDLIMQVSNGEIDYAICDNDLAKLNKTYYPNLNIDLAVSFDQRASWAVRKTSPLLG
EAATKWHQENMTSPAYQASSKRYFEISKRTPHGSILSIKDGKISHFDTLFKKYAKDIDWDWRILASLAYTESNFDTTAVS
WAGAKGLMQLMPRTARAMGVPPGKEQNPEESIKAAVKYIAATSRSFNAIKDENERMKFVLAAYNAGIGHVLDAMALAEKY
GKNKYVWNNSVDNYILLKSNEEYFNDPVCKNGYFRGVETYNFVKEVMNRGEVYKKKIKD

Sequences:

>Translated_459_residues
MKNVWLLVLACICMTACRNRQQSAEVTNYDLPQIKDSGELVVLTLNSSTSYFDYRGEPMGFQYELADQFARSLDVKLKIK
VAQNARDLVHKLLQGEGDLIAYNLPVTKEFKDSVEFCGEDIITHQVLVQRNTQKKKKALNNVTELIGKEVYVKPGKYLER
LINLDKELGGGILIHEVDNDSITTEDLIMQVSNGEIDYAICDNDLAKLNKTYYPNLNIDLAVSFDQRASWAVRKTSPLLG
EAATKWHQENMTSPAYQASSKRYFEISKRTPHGSILSIKDGKISHFDTLFKKYAKDIDWDWRILASLAYTESNFDTTAVS
WAGAKGLMQLMPRTARAMGVPPGKEQNPEESIKAAVKYIAATSRSFNAIKDENERMKFVLAAYNAGIGHVLDAMALAEKY
GKNKYVWNNSVDNYILLKSNEEYFNDPVCKNGYFRGVETYNFVKEVMNRGEVYKKKIKD
>Mature_459_residues
MKNVWLLVLACICMTACRNRQQSAEVTNYDLPQIKDSGELVVLTLNSSTSYFDYRGEPMGFQYELADQFARSLDVKLKIK
VAQNARDLVHKLLQGEGDLIAYNLPVTKEFKDSVEFCGEDIITHQVLVQRNTQKKKKALNNVTELIGKEVYVKPGKYLER
LINLDKELGGGILIHEVDNDSITTEDLIMQVSNGEIDYAICDNDLAKLNKTYYPNLNIDLAVSFDQRASWAVRKTSPLLG
EAATKWHQENMTSPAYQASSKRYFEISKRTPHGSILSIKDGKISHFDTLFKKYAKDIDWDWRILASLAYTESNFDTTAVS
WAGAKGLMQLMPRTARAMGVPPGKEQNPEESIKAAVKYIAATSRSFNAIKDENERMKFVLAAYNAGIGHVLDAMALAEKY
GKNKYVWNNSVDNYILLKSNEEYFNDPVCKNGYFRGVETYNFVKEVMNRGEVYKKKIKD

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=422, Percent_Identity=31.5165876777251, Blast_Score=169, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 52088; Mature: 52088

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNVWLLVLACICMTACRNRQQSAEVTNYDLPQIKDSGELVVLTLNSSTSYFDYRGEPMG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
FQYELADQFARSLDVKLKIKVAQNARDLVHKLLQGEGDLIAYNLPVTKEFKDSVEFCGED
EEHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
IITHQVLVQRNTQKKKKALNNVTELIGKEVYVKPGKYLERLINLDKELGGGILIHEVDND
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCHHHHCCCEEEEECCCC
SITTEDLIMQVSNGEIDYAICDNDLAKLNKTYYPNLNIDLAVSFDQRASWAVRKTSPLLG
CCCHHHHEEEECCCEEEEEECCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCCHHH
EAATKWHQENMTSPAYQASSKRYFEISKRTPHGSILSIKDGKISHFDTLFKKYAKDIDWD
HHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
WRILASLAYTESNFDTTAVSWAGAKGLMQLMPRTARAMGVPPGKEQNPEESIKAAVKYIA
HHHHHHHHHCCCCCCCCEEEHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ATSRSFNAIKDENERMKFVLAAYNAGIGHVLDAMALAEKYGKNKYVWNNSVDNYILLKSN
HHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEECC
EEYFNDPVCKNGYFRGVETYNFVKEVMNRGEVYKKKIKD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCC
>Mature Secondary Structure
MKNVWLLVLACICMTACRNRQQSAEVTNYDLPQIKDSGELVVLTLNSSTSYFDYRGEPMG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
FQYELADQFARSLDVKLKIKVAQNARDLVHKLLQGEGDLIAYNLPVTKEFKDSVEFCGED
EEHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHH
IITHQVLVQRNTQKKKKALNNVTELIGKEVYVKPGKYLERLINLDKELGGGILIHEVDND
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCHHHHCCCEEEEECCCC
SITTEDLIMQVSNGEIDYAICDNDLAKLNKTYYPNLNIDLAVSFDQRASWAVRKTSPLLG
CCCHHHHEEEECCCEEEEEECCCHHHHHCCCCCCCCCEEEEEECCCCCCEEEECCCCHHH
EAATKWHQENMTSPAYQASSKRYFEISKRTPHGSILSIKDGKISHFDTLFKKYAKDIDWD
HHHHHHHHHCCCCCHHHCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCC
WRILASLAYTESNFDTTAVSWAGAKGLMQLMPRTARAMGVPPGKEQNPEESIKAAVKYIA
HHHHHHHHHCCCCCCCCEEEHHCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHH
ATSRSFNAIKDENERMKFVLAAYNAGIGHVLDAMALAEKYGKNKYVWNNSVDNYILLKSN
HHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEECC
EEYFNDPVCKNGYFRGVETYNFVKEVMNRGEVYKKKIKD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA