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The map label for this gene is macB [H]

Identifier: 150004881

GI number: 150004881

Start: 3020273

End: 3021574

Strand: Direct

Name: macB [H]

Synonym: BVU_2344

Alternate gene names: 150004881

Gene position: 3020273-3021574 (Clockwise)

Preceding gene: 150004880

Following gene: 150004882

Centisome position: 58.5

GC content: 45.08

Gene sequence:

>1302_bases
ATGATAAAATATTATTGGAAGCAGGCCTGGGAGCTGCTGAAACAGCATAAACTGTTCAGTGTGCTTTATATAACAGGTGC
GGGATTGGCTATTGCCATGACTATGGTTGTTTTTGTGGCACATTATATAAGAGTGGCACCTGTTTATCCGGAGACAAACC
GTGCTGAGACGTGGGTTTTGAAGTCTGTTACGGTGCAACGGGTGAAAACCCGTGGAAGTGGCAGTTGGCAAAGCTCTCAC
CAATTGGTACGTGACTGGTGGTATCCCATGCAGGAGGCCGAGCAGGTTTCTGCTGTATATAACTCGTGGGAATTGGATGA
CTACATTCAACGTGAGAACTTGGGTTCGGAACTGAATGTGAAAGTGAAATATACCGATCCTGCTTTTTTCCGTATCTTTC
AATTCTCTTTTTTAGCTGGGAAGCCATTCTCGCAGGCCGATTTTGAGAGTGGTATCATGAATGCAGTGGTAGGGGAGGAC
TTGGCACGTCGTCTGTTCGGCACCACAGAGGTGGTTGGCAAGACTTTCAGCTTGAATTATACGGACTGTCGCATTGTGGG
AGTTGTGAAAGATGCAAGTTTCCTGACAAGAGACTCCTTTGCACAATTATATCTGCCTTATACTACAGTGGCAGGCTATG
ATAAGGATTCTAAAAGTGATGCCGGTATGTTGGGACCCTATACGGTTTATTTCAAAGTGAAGGATGATGCCATGGGAGCG
GCTTTGGAGGCGGCCATGCATGAAATGGTCCGTAAATATAATACTTCACAGGAAGAGAATAAATTGGTTTTATCAGGTCC
GGATGTTTATTGGAAAAGTGTCTATCGGCGTGGAAATGTTCCTTTGGACTGGTGGGAGCTGATACGTCTTTGGGGAGGGC
TTGTTTTGATTTTCTTATTGGTGCCTGCTCTTAATTTATGTGCGATGATCAGTACGCGCATGGAAAACCGTCTTCCGGAA
ATGGGTATCTGTAAAGCCTTCGGTGCCGACCGCGGACGTTTGCTTCGTCAGATATTGATCGAGAATTTGATATTGACCTG
TTTGGGGGGGCTGCTGGGCTTATGTTGGGTCTGGACGATATTGATAGCCGGACGTAATTGGGTGTTTACTTTGTTTGAGC
GTTACGGAAATTCCGCTCCTGAAGGAGTAGATACAATCGTCAGTTTTGATATGCTGTTCTCTCCATGGATTTTCTGTGCA
GGTTTTATCGTTTGTCTTTTGCTGAATTTATTCTCTGCATTATGGCCGGCGTGGAAGGCACTGGGTAAGGATATCGTTTA
TTCATTGAATCAGAAGAAATAA

Upstream 100 bases:

>100_bases
TAAAACTTTCTCTCTTAAATTAAAGTAGCGGGAAACCGGGTGGAAGGGAGGCATATTCCCTTCTGCTCGCCCCGGATACT
GATGATAATTCGTTCTCATT

Downstream 100 bases:

>100_bases
AAGGAGGGGGATGCGATGCTACATTTGATAGGTAAGAATTTATGGGCACGCCGATACCGCAATGGCTGGTTGTTGGCAGA
GTTGATCATTGTATCTATGG

Product: putative ABC transporter permease component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MIKYYWKQAWELLKQHKLFSVLYITGAGLAIAMTMVVFVAHYIRVAPVYPETNRAETWVLKSVTVQRVKTRGSGSWQSSH
QLVRDWWYPMQEAEQVSAVYNSWELDDYIQRENLGSELNVKVKYTDPAFFRIFQFSFLAGKPFSQADFESGIMNAVVGED
LARRLFGTTEVVGKTFSLNYTDCRIVGVVKDASFLTRDSFAQLYLPYTTVAGYDKDSKSDAGMLGPYTVYFKVKDDAMGA
ALEAAMHEMVRKYNTSQEENKLVLSGPDVYWKSVYRRGNVPLDWWELIRLWGGLVLIFLLVPALNLCAMISTRMENRLPE
MGICKAFGADRGRLLRQILIENLILTCLGGLLGLCWVWTILIAGRNWVFTLFERYGNSAPEGVDTIVSFDMLFSPWIFCA
GFIVCLLLNLFSALWPAWKALGKDIVYSLNQKK

Sequences:

>Translated_433_residues
MIKYYWKQAWELLKQHKLFSVLYITGAGLAIAMTMVVFVAHYIRVAPVYPETNRAETWVLKSVTVQRVKTRGSGSWQSSH
QLVRDWWYPMQEAEQVSAVYNSWELDDYIQRENLGSELNVKVKYTDPAFFRIFQFSFLAGKPFSQADFESGIMNAVVGED
LARRLFGTTEVVGKTFSLNYTDCRIVGVVKDASFLTRDSFAQLYLPYTTVAGYDKDSKSDAGMLGPYTVYFKVKDDAMGA
ALEAAMHEMVRKYNTSQEENKLVLSGPDVYWKSVYRRGNVPLDWWELIRLWGGLVLIFLLVPALNLCAMISTRMENRLPE
MGICKAFGADRGRLLRQILIENLILTCLGGLLGLCWVWTILIAGRNWVFTLFERYGNSAPEGVDTIVSFDMLFSPWIFCA
GFIVCLLLNLFSALWPAWKALGKDIVYSLNQKK
>Mature_433_residues
MIKYYWKQAWELLKQHKLFSVLYITGAGLAIAMTMVVFVAHYIRVAPVYPETNRAETWVLKSVTVQRVKTRGSGSWQSSH
QLVRDWWYPMQEAEQVSAVYNSWELDDYIQRENLGSELNVKVKYTDPAFFRIFQFSFLAGKPFSQADFESGIMNAVVGED
LARRLFGTTEVVGKTFSLNYTDCRIVGVVKDASFLTRDSFAQLYLPYTTVAGYDKDSKSDAGMLGPYTVYFKVKDDAMGA
ALEAAMHEMVRKYNTSQEENKLVLSGPDVYWKSVYRRGNVPLDWWELIRLWGGLVLIFLLVPALNLCAMISTRMENRLPE
MGICKAFGADRGRLLRQILIENLILTCLGGLLGLCWVWTILIAGRNWVFTLFERYGNSAPEGVDTIVSFDMLFSPWIFCA
GFIVCLLLNLFSALWPAWKALGKDIVYSLNQKK

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 49431; Mature: 49431

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKYYWKQAWELLKQHKLFSVLYITGAGLAIAMTMVVFVAHYIRVAPVYPETNRAETWVL
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KSVTVQRVKTRGSGSWQSSHQLVRDWWYPMQEAEQVSAVYNSWELDDYIQRENLGSELNV
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEE
KVKYTDPAFFRIFQFSFLAGKPFSQADFESGIMNAVVGEDLARRLFGTTEVVGKTFSLNY
EEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCC
TDCRIVGVVKDASFLTRDSFAQLYLPYTTVAGYDKDSKSDAGMLGPYTVYFKVKDDAMGA
CCEEEEEEECCCHHHHHHHHHHHEECHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHH
ALEAAMHEMVRKYNTSQEENKLVLSGPDVYWKSVYRRGNVPLDWWELIRLWGGLVLIFLL
HHHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VPALNLCAMISTRMENRLPEMGICKAFGADRGRLLRQILIENLILTCLGGLLGLCWVWTI
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAGRNWVFTLFERYGNSAPEGVDTIVSFDMLFSPWIFCAGFIVCLLLNLFSALWPAWKA
HHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKDIVYSLNQKK
HHHHHHHHCCCCC
>Mature Secondary Structure
MIKYYWKQAWELLKQHKLFSVLYITGAGLAIAMTMVVFVAHYIRVAPVYPETNRAETWVL
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KSVTVQRVKTRGSGSWQSSHQLVRDWWYPMQEAEQVSAVYNSWELDDYIQRENLGSELNV
HHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEE
KVKYTDPAFFRIFQFSFLAGKPFSQADFESGIMNAVVGEDLARRLFGTTEVVGKTFSLNY
EEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEEECCC
TDCRIVGVVKDASFLTRDSFAQLYLPYTTVAGYDKDSKSDAGMLGPYTVYFKVKDDAMGA
CCEEEEEEECCCHHHHHHHHHHHEECHHHCCCCCCCCCCCCCCCCCEEEEEEECCCHHHH
ALEAAMHEMVRKYNTSQEENKLVLSGPDVYWKSVYRRGNVPLDWWELIRLWGGLVLIFLL
HHHHHHHHHHHHHCCCHHHCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VPALNLCAMISTRMENRLPEMGICKAFGADRGRLLRQILIENLILTCLGGLLGLCWVWTI
HHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIAGRNWVFTLFERYGNSAPEGVDTIVSFDMLFSPWIFCAGFIVCLLLNLFSALWPAWKA
HHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKDIVYSLNQKK
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]