Click here to switch to the map view.

The map label for this gene is cdd [H]

Identifier: 150004871

GI number: 150004871

Start: 3012747

End: 3013226

Strand: Reverse

Name: cdd [H]

Synonym: BVU_2334

Alternate gene names: 150004871

Gene position: 3013226-3012747 (Counterclockwise)

Preceding gene: 150004873

Following gene: 150004870

Centisome position: 58.36

GC content: 40.83

Gene sequence:

>480_bases
ATGAAACAAATCAAACTGGAAATAAACATAGAGGCTTGCCATTATGACGAACTAACAGAGAAGGACCGCAAACTGATAGA
CGCCGCGTGTGAAGCAACGAAAAGAAGCTATGCTCCTTACTCACATTTTGCTGTTGGAGCCGCCGCACTGTTGGAAAATG
ATATCGTCATTACCGGAACCAATCAAGAAAATGCAGCCTACCCATCTGGTCTTTGTGCAGAACGTACCACTTTGTTTTAT
GCCAATTCTCAATATCCGGATCAAGCAGTAAAAACACTCGCCATTGCTGCCCGCACAGAAAATGGTTTTCTTGACACACC
TATTCCTCCTTGCGGAGCCTGTCGGCAAGTATTATTAGAAACTGAAAAACGATATGGAAAACCTATGCGGATACTGCTTT
ATAGTAAGACTGATATTTATATATTAGAAAACGTAAGCGGACTTTTACCTTTATCGTTTGATGGAAATTATCTGAAATGA

Upstream 100 bases:

>100_bases
ATAAGAAAACAAATAAATTTAAAACCAGATTTTAGAAAAGAAACATTGGGAGATTAAAAACAAAACATTACATTTGCAAG
AAAACAAAGAGGAACGTATC

Downstream 100 bases:

>100_bases
TACCTACCATCCGTCTGCACAGCCAACAGTTAATAAATCCGGTTTTCAATAATCCGAAAGATCTTGTATCATGGATGGGA
GGCATTCAAGCGCAAGATTA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MKQIKLEINIEACHYDELTEKDRKLIDAACEATKRSYAPYSHFAVGAAALLENDIVITGTNQENAAYPSGLCAERTTLFY
ANSQYPDQAVKTLAIAARTENGFLDTPIPPCGACRQVLLETEKRYGKPMRILLYSKTDIYILENVSGLLPLSFDGNYLK

Sequences:

>Translated_159_residues
MKQIKLEINIEACHYDELTEKDRKLIDAACEATKRSYAPYSHFAVGAAALLENDIVITGTNQENAAYPSGLCAERTTLFY
ANSQYPDQAVKTLAIAARTENGFLDTPIPPCGACRQVLLETEKRYGKPMRILLYSKTDIYILENVSGLLPLSFDGNYLK
>Mature_159_residues
MKQIKLEINIEACHYDELTEKDRKLIDAACEATKRSYAPYSHFAVGAAALLENDIVITGTNQENAAYPSGLCAERTTLFY
ANSQYPDQAVKTLAIAARTENGFLDTPIPPCGACRQVLLETEKRYGKPMRILLYSKTDIYILENVSGLLPLSFDGNYLK

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=132, Percent_Identity=41.6666666666667, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17551074, Length=136, Percent_Identity=36.7647058823529, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540514, Length=132, Percent_Identity=37.8787878787879, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6323274, Length=142, Percent_Identity=34.5070422535211, Blast_Score=78, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24582741, Length=132, Percent_Identity=37.1212121212121, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582744, Length=103, Percent_Identity=38.8349514563107, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19920920, Length=115, Percent_Identity=38.2608695652174, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 17701; Mature: 17701

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIKLEINIEACHYDELTEKDRKLIDAACEATKRSYAPYSHFAVGAAALLENDIVITGT
CCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECC
NQENAAYPSGLCAERTTLFYANSQYPDQAVKTLAIAARTENGFLDTPIPPCGACRQVLLE
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHEEEECCCCEECCCCCCHHHHHHHHHH
TEKRYGKPMRILLYSKTDIYILENVSGLLPLSFDGNYLK
HHHHCCCCEEEEEECCCCEEEEECCCCEEEECCCCCCCC
>Mature Secondary Structure
MKQIKLEINIEACHYDELTEKDRKLIDAACEATKRSYAPYSHFAVGAAALLENDIVITGT
CCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECC
NQENAAYPSGLCAERTTLFYANSQYPDQAVKTLAIAARTENGFLDTPIPPCGACRQVLLE
CCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHEEEECCCCEECCCCCCHHHHHHHHHH
TEKRYGKPMRILLYSKTDIYILENVSGLLPLSFDGNYLK
HHHHCCCCEEEEEECCCCEEEEECCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]