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The map label for this gene is mro [H]

Identifier: 150004864

GI number: 150004864

Start: 3003748

End: 3004842

Strand: Reverse

Name: mro [H]

Synonym: BVU_2327

Alternate gene names: 150004864

Gene position: 3004842-3003748 (Counterclockwise)

Preceding gene: 150004865

Following gene: 150004863

Centisome position: 58.2

GC content: 41.92

Gene sequence:

>1095_bases
ATGATAAACACATCTACTTCCGATGAGAATTTATGCGGCCTGAAACGGGCCGATTTTCAGACAACAGTGAACGGGAAACA
AACAGACCTCTTCATTCTGAAAAATGAAAACGGAGCTGAAATAGCTGTCACCAACTATGGTGGAGCAGTATTAGCTATTA
TGGTTCCGGACAAAAACGGTAAATATGCCAATGTCATTCAAGGACATGATAGTATAACCCATGTTATCAATAGCCACGAA
CCTTTCCTCAGTACTCTTATCGGTCGTTACGGAAACCGTATAGCAGGAGGCAAATTCATTTTAGAAGGGAAAGAATATTC
ACTGACTATCAACAATGGTCCCAACTCGCTGCATGGCGGTCCTACCGGATTTCATACCCGCATTTGGGATGCAGAACAGG
AAACTCCCCAAAGCTTGAAATTGCATTATTTATCTGCTGATGGCGAAGAAGGATTTCCGGGAAATTTGGATATTCACGTA
ACGTACACTTTAAGTAATCAAAATGAATTCATCATTACTTACCACGCTACAACAGACAAAACAACATTGGTAAATCTTAC
TCACCACGGTTTTTTCAGCCTATCAGGCATTGCCAATCCTACGGCAACCGTTGATAACAACATCGTAACCATTAATGCTG
ATTTTTATACTCCGATAGATAATGTATCCATCCCTACAGGCGAAATTGCCAAAGTAGAAGGTACTCCTATGGACTTTCGT
ACTCCTCAAAGAGTAGACAGTAGAATCAATGACCCATTCGAACAGCTAGAATTCGGTGCCGGCTATGACCACTGCTATGT
ATTAAACAAACGTGAAGCAGGCACACTGAGTTTTGCAGCAAAATGTGTGGATCCCGAAAGCGGTCGTAGCATGGAAGTAT
ACACTACAGAGCCCGGTGTACAAGTTTATACTTCAAACTGGCACAATGGTTTCGAAGGTGCTCATGGAGCAACTTTCCCA
GCAAGAAGTGCCATCTGTTTTGAAGCACAACATTTTCCTGATACGCCCAATAAAGGCCATTTCCCTTCTTGTGTTCTACA
TCCGGGGGAAACTTACAATCAAGTAACCATCTACAAATTCGGTGTAGAAAAATAA

Upstream 100 bases:

>100_bases
GTTTAGTCCGTTCACTTTTATAGAAAAAGTTTGGGAATACCGAAGAAAATCTTTTTATTTGCATTAGTTTTATACATAAA
ATAAAAAGATTTTCAATAAC

Downstream 100 bases:

>100_bases
TTTTATGAAATAACCTAATTAATAAACTTATAATTTTTTCAAAACCATGAATCAACAAAAACAGAACGGTAATATCATCG
CTATCATTACAATGTTCTTC

Product: aldose 1-epimerase precursor

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MINTSTSDENLCGLKRADFQTTVNGKQTDLFILKNENGAEIAVTNYGGAVLAIMVPDKNGKYANVIQGHDSITHVINSHE
PFLSTLIGRYGNRIAGGKFILEGKEYSLTINNGPNSLHGGPTGFHTRIWDAEQETPQSLKLHYLSADGEEGFPGNLDIHV
TYTLSNQNEFIITYHATTDKTTLVNLTHHGFFSLSGIANPTATVDNNIVTINADFYTPIDNVSIPTGEIAKVEGTPMDFR
TPQRVDSRINDPFEQLEFGAGYDHCYVLNKREAGTLSFAAKCVDPESGRSMEVYTTEPGVQVYTSNWHNGFEGAHGATFP
ARSAICFEAQHFPDTPNKGHFPSCVLHPGETYNQVTIYKFGVEK

Sequences:

>Translated_364_residues
MINTSTSDENLCGLKRADFQTTVNGKQTDLFILKNENGAEIAVTNYGGAVLAIMVPDKNGKYANVIQGHDSITHVINSHE
PFLSTLIGRYGNRIAGGKFILEGKEYSLTINNGPNSLHGGPTGFHTRIWDAEQETPQSLKLHYLSADGEEGFPGNLDIHV
TYTLSNQNEFIITYHATTDKTTLVNLTHHGFFSLSGIANPTATVDNNIVTINADFYTPIDNVSIPTGEIAKVEGTPMDFR
TPQRVDSRINDPFEQLEFGAGYDHCYVLNKREAGTLSFAAKCVDPESGRSMEVYTTEPGVQVYTSNWHNGFEGAHGATFP
ARSAICFEAQHFPDTPNKGHFPSCVLHPGETYNQVTIYKFGVEK
>Mature_364_residues
MINTSTSDENLCGLKRADFQTTVNGKQTDLFILKNENGAEIAVTNYGGAVLAIMVPDKNGKYANVIQGHDSITHVINSHE
PFLSTLIGRYGNRIAGGKFILEGKEYSLTINNGPNSLHGGPTGFHTRIWDAEQETPQSLKLHYLSADGEEGFPGNLDIHV
TYTLSNQNEFIITYHATTDKTTLVNLTHHGFFSLSGIANPTATVDNNIVTINADFYTPIDNVSIPTGEIAKVEGTPMDFR
TPQRVDSRINDPFEQLEFGAGYDHCYVLNKREAGTLSFAAKCVDPESGRSMEVYTTEPGVQVYTSNWHNGFEGAHGATFP
ARSAICFEAQHFPDTPNKGHFPSCVLHPGETYNQVTIYKFGVEK

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=328, Percent_Identity=39.9390243902439, Blast_Score=239, Evalue=4e-63,
Organism=Escherichia coli, GI1786971, Length=342, Percent_Identity=32.7485380116959, Blast_Score=194, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17557428, Length=329, Percent_Identity=31.0030395136778, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115533334, Length=329, Percent_Identity=31.0030395136778, Blast_Score=175, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319493, Length=334, Percent_Identity=26.6467065868263, Blast_Score=110, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6322004, Length=357, Percent_Identity=23.5294117647059, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324399, Length=320, Percent_Identity=25, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583720, Length=336, Percent_Identity=36.0119047619048, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI24668278, Length=361, Percent_Identity=32.6869806094183, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI24659048, Length=340, Percent_Identity=35.8823529411765, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24668282, Length=339, Percent_Identity=32.4483775811209, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24641876, Length=344, Percent_Identity=28.4883720930233, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 39971; Mature: 39971

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINTSTSDENLCGLKRADFQTTVNGKQTDLFILKNENGAEIAVTNYGGAVLAIMVPDKNG
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEEECCCEEEEEEEECCCC
KYANVIQGHDSITHVINSHEPFLSTLIGRYGNRIAGGKFILEGKEYSLTINNGPNSLHGG
CEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCEECCCEEEEECCEEEEEECCCCCCCCCC
PTGFHTRIWDAEQETPQSLKLHYLSADGEEGFPGNLDIHVTYTLSNQNEFIITYHATTDK
CCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
TTLVNLTHHGFFSLSGIANPTATVDNNIVTINADFYTPIDNVSIPTGEIAKVEGTPMDFR
EEEEEEECCCEEEECCCCCCCEECCCCEEEEEECEECCCCCCCCCCCCEEEECCCCCCCC
TPQRVDSRINDPFEQLEFGAGYDHCYVLNKREAGTLSFAAKCVDPESGRSMEVYTTEPGV
CHHHHHHHCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCC
QVYTSNWHNGFEGAHGATFPARSAICFEAQHFPDTPNKGHFPSCVLHPGETYNQVTIYKF
EEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEEE
GVEK
CCCC
>Mature Secondary Structure
MINTSTSDENLCGLKRADFQTTVNGKQTDLFILKNENGAEIAVTNYGGAVLAIMVPDKNG
CCCCCCCCCCCCCCCCCCCEEECCCCCEEEEEEECCCCCEEEEEECCCEEEEEEEECCCC
KYANVIQGHDSITHVINSHEPFLSTLIGRYGNRIAGGKFILEGKEYSLTINNGPNSLHGG
CEEEEEECCCHHHHHHCCCCHHHHHHHHHHCCEECCCEEEEECCEEEEEECCCCCCCCCC
PTGFHTRIWDAEQETPQSLKLHYLSADGEEGFPGNLDIHVTYTLSNQNEFIITYHATTDK
CCCCEEEEECCCCCCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCCEEEEEECCCCC
TTLVNLTHHGFFSLSGIANPTATVDNNIVTINADFYTPIDNVSIPTGEIAKVEGTPMDFR
EEEEEEECCCEEEECCCCCCCEECCCCEEEEEECEECCCCCCCCCCCCEEEECCCCCCCC
TPQRVDSRINDPFEQLEFGAGYDHCYVLNKREAGTLSFAAKCVDPESGRSMEVYTTEPGV
CHHHHHHHCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCEEEEEECCCCC
QVYTSNWHNGFEGAHGATFPARSAICFEAQHFPDTPNKGHFPSCVLHPGETYNQVTIYKF
EEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCEEEEEEE
GVEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3012466; 3531172 [H]