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The map label for this gene is prmA

Identifier: 150004826

GI number: 150004826

Start: 2961240

End: 2962085

Strand: Reverse

Name: prmA

Synonym: BVU_2289

Alternate gene names: 150004826

Gene position: 2962085-2961240 (Counterclockwise)

Preceding gene: 150004827

Following gene: 150004822

Centisome position: 57.37

GC content: 44.33

Gene sequence:

>846_bases
ATGAAATATTTAGAAGTAACCTTTACAACACATCCCTGTAATGAGACAGTGAATGATGTAGTGTCCGCATTGGCCGGAGA
AATAGGATTTGAAAGTTTTGTAGAATGTGAAGGGGGAATACAGGCCTATATCCAGCAAACTCTCTTTGACGAGGAAGCAC
TGAAAGAAATGGTTGCGAACTTCCCTTTACCTGACACCCGGATAGAATACACCATAAAGGAAGCCGAAGACAAAAACTGG
AATGAAGAATGGGAGAAAAACTTCTTTCAACCCATCGTCATAGGTGACCGTTGCTGCATTCACAGCACGTTCCACAAAGA
CACTCCGAAAACTGAGTATGAAATTCTGATTAACCCGCAAATGGCTTTCGGCACAGGGCATCATGAAACGACCAGCTCTA
TAATCAGCGAGCTGTTAGAAGCCGACCTGAAAGGAAAATCAGTCCTGGATATGGGATGCGGCACTTCTATTCTTGCCATC
CTTGCCTCCATGCGAGGAGCCAATCCTGTGACAGCCATCGACATTGACGACTGGTGCGTCAACAATTCAAAAGACAACAT
TGCACTGAACCATATCCATAACATTACAGTGGAACTGGGTGACGCCAATCTGCTGAAAGGGCGCAAAGCGTTTGATGTGA
TTATTGCCAACATTAACCGGAATATTCTTCTGGCAGACCTTCCCCATTATGCCGCCTGTATGCATCCGGGTTCGGAAATA
TTTATGAGTGGATTCTATATACAGGATATTCCTTTTATCCGCGAAAAAGCGGAGAGTCTGGGAATGGAGTTCGTACATCA
TCGGGAAAAGAACAACTGGGCAGCTGTGAAATTCATCATGAAATAA

Upstream 100 bases:

>100_bases
CCCACGTTCTATGTGGACGGGGTGAAAGTGCATGAAGCGGGCATCTTCAAAAATGAGATGGAGGCATTGCTCCGTAAAGT
GATAGAATAAACGAAAAGAT

Downstream 100 bases:

>100_bases
TACCATTTTCAAGTATGGCAAAGACGCGATAAAGACGGAATTGCCACCAACCACGCAGGATATGCATTGATTTATTCGAG
GACAAAAGAACGGATTTTCT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEGGIQAYIQQTLFDEEALKEMVANFPLPDTRIEYTIKEAEDKNW
NEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQMAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAI
LASMRGANPVTAIDIDDWCVNNSKDNIALNHIHNITVELGDANLLKGRKAFDVIIANINRNILLADLPHYAACMHPGSEI
FMSGFYIQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK

Sequences:

>Translated_281_residues
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEGGIQAYIQQTLFDEEALKEMVANFPLPDTRIEYTIKEAEDKNW
NEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQMAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAI
LASMRGANPVTAIDIDDWCVNNSKDNIALNHIHNITVELGDANLLKGRKAFDVIIANINRNILLADLPHYAACMHPGSEI
FMSGFYIQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK
>Mature_281_residues
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEGGIQAYIQQTLFDEEALKEMVANFPLPDTRIEYTIKEAEDKNW
NEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQMAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAI
LASMRGANPVTAIDIDDWCVNNSKDNIALNHIHNITVELGDANLLKGRKAFDVIIANINRNILLADLPHYAACMHPGSEI
FMSGFYIQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=175, Percent_Identity=36.5714285714286, Blast_Score=95, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_BACV8 (A6L2N4)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299570.1
- ProteinModelPortal:   A6L2N4
- SMR:   A6L2N4
- STRING:   A6L2N4
- GeneID:   5303253
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_2289
- NMPDR:   fig|435590.6.peg.2147
- eggNOG:   COG2264
- HOGENOM:   HBG405568
- OMA:   AIDIDDW
- ProtClustDB:   PRK00517
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31657; Mature: 31657

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEGGIQAYIQQTLFDEEALKEMVAN
CCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
FPLPDTRIEYTIKEAEDKNWNEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQ
CCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEECCCCEECCCCCCCCCCCCEEEEECCC
MAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAILASMRGANPVTAIDIDDWCV
EEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHC
NNSKDNIALNHIHNITVELGDANLLKGRKAFDVIIANINRNILLADLPHYAACMHPGSEI
CCCCCCEEEEEEEEEEEEECCCHHHCCCCEEEEEEEECCCCEEEEECCHHHHHHCCCHHH
FMSGFYIQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK
HCCCEEECCCHHHHHHHHHHCHHHHHHHCCCCEEEEEEEEC
>Mature Secondary Structure
MKYLEVTFTTHPCNETVNDVVSALAGEIGFESFVECEGGIQAYIQQTLFDEEALKEMVAN
CCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHH
FPLPDTRIEYTIKEAEDKNWNEEWEKNFFQPIVIGDRCCIHSTFHKDTPKTEYEILINPQ
CCCCCCEEEEEEECCCCCCCCHHHHHCCCCCEEECCCCEECCCCCCCCCCCCEEEEECCC
MAFGTGHHETTSSIISELLEADLKGKSVLDMGCGTSILAILASMRGANPVTAIDIDDWCV
EEECCCCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCEEEEECCHHHC
NNSKDNIALNHIHNITVELGDANLLKGRKAFDVIIANINRNILLADLPHYAACMHPGSEI
CCCCCCEEEEEEEEEEEEECCCHHHCCCCEEEEEEEECCCCEEEEECCHHHHHHCCCHHH
FMSGFYIQDIPFIREKAESLGMEFVHHREKNNWAAVKFIMK
HCCCEEECCCHHHHHHHHHHCHHHHHHHCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA