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The map label for this gene is plsC [H]

Identifier: 150004792

GI number: 150004792

Start: 2916385

End: 2917143

Strand: Reverse

Name: plsC [H]

Synonym: BVU_2255

Alternate gene names: 150004792

Gene position: 2917143-2916385 (Counterclockwise)

Preceding gene: 150004793

Following gene: 150004790

Centisome position: 56.5

GC content: 40.58

Gene sequence:

>759_bases
ATGAAAGTACTATATATTTTATACCAACTATTCATAGCACTTCCCATTTTGCTGGTATTAACCATACTTACAGCAATAGT
TACCATTATTGGTTCATGGATAGGCAATCCGCATTTTTGGGGATATTATCCGGGAAAAATATGGTCACAGCTTTTCTGCT
ATGTATTACTTATTCCTGTCAAGGTAGTAGGACATCCGGAAGTACTTAAAAAAACATCCTACGTGTTTGTAGCCAATCAT
CAAGGGTCTTTCGATATCTTCCTGATTTATGGTTTTCTGGGACGAAACTTTAAATGGATGATGAAAAAAAGTCTGCGCAA
AATGCCTTTCGTCGGCAAAGCCTGTGAAGCTGCCGGACATATATTCGTTGATAAATCCGGTCCCAAGAAGGTAATAGAAA
CCATAGAACACGCCCGTCACGTACTACAGGATGGAACTTCTCTAGTGGTATTTCCCGAAGGTGCACGTACTTTTACCGGG
CACATGGGATATTTTAAGAAAGGTGCTTTCCAACTGGCAGATGATTTGCAACTTCCCGTAGTACCACTCACTATTATCGG
CTCCTTTAATATTCTTCCCCGTACCGGCGGTTTTGTATCCTGGCATCCTATGACATTAGTCGTACATAAGCCCATTTATC
CGCAAAGCCAGGGAATGGAAAACATCAAAGCAACCATGGAAGAGGCTTACAGGGAAATTGAGAAAGACTTACCTGAAAAA
TATCAAGGAAAAATAGACAATCCAGACCAAGACAGATAA

Upstream 100 bases:

>100_bases
GTTCCCTATGCGCCTTGGAGCATGGCCGGAAATTACAGTAATCACGTTACATAAAATATAAAATAGTTTTTCTATCTTTG
TACAACTAAAATTCAGACAA

Downstream 100 bases:

>100_bases
AAAAAGGCTCCTCATTAATGGGGAGCTTTTAATTTTTCCATATTCGAACGGGCTACTGTCACATAATCCTTTACCAAGGA
GTTGTTTTTAAATCGGTCAG

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MKVLYILYQLFIALPILLVLTILTAIVTIIGSWIGNPHFWGYYPGKIWSQLFCYVLLIPVKVVGHPEVLKKTSYVFVANH
QGSFDIFLIYGFLGRNFKWMMKKSLRKMPFVGKACEAAGHIFVDKSGPKKVIETIEHARHVLQDGTSLVVFPEGARTFTG
HMGYFKKGAFQLADDLQLPVVPLTIIGSFNILPRTGGFVSWHPMTLVVHKPIYPQSQGMENIKATMEEAYREIEKDLPEK
YQGKIDNPDQDR

Sequences:

>Translated_252_residues
MKVLYILYQLFIALPILLVLTILTAIVTIIGSWIGNPHFWGYYPGKIWSQLFCYVLLIPVKVVGHPEVLKKTSYVFVANH
QGSFDIFLIYGFLGRNFKWMMKKSLRKMPFVGKACEAAGHIFVDKSGPKKVIETIEHARHVLQDGTSLVVFPEGARTFTG
HMGYFKKGAFQLADDLQLPVVPLTIIGSFNILPRTGGFVSWHPMTLVVHKPIYPQSQGMENIKATMEEAYREIEKDLPEK
YQGKIDNPDQDR
>Mature_252_residues
MKVLYILYQLFIALPILLVLTILTAIVTIIGSWIGNPHFWGYYPGKIWSQLFCYVLLIPVKVVGHPEVLKKTSYVFVANH
QGSFDIFLIYGFLGRNFKWMMKKSLRKMPFVGKACEAAGHIFVDKSGPKKVIETIEHARHVLQDGTSLVVFPEGARTFTG
HMGYFKKGAFQLADDLQLPVVPLTIIGSFNILPRTGGFVSWHPMTLVVHKPIYPQSQGMENIKATMEEAYREIEKDLPEK
YQGKIDNPDQDR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=133, Percent_Identity=35.3383458646617, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI15100175, Length=133, Percent_Identity=35.3383458646617, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17564032, Length=195, Percent_Identity=25.1282051282051, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=241, Percent_Identity=28.6307053941909, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641614, Length=195, Percent_Identity=27.1794871794872, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641612, Length=195, Percent_Identity=27.1794871794872, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28644; Mature: 28644

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLYILYQLFIALPILLVLTILTAIVTIIGSWIGNPHFWGYYPGKIWSQLFCYVLLIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KVVGHPEVLKKTSYVFVANHQGSFDIFLIYGFLGRNFKWMMKKSLRKMPFVGKACEAAGH
HHCCCHHHHHCCCEEEEECCCCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHCCC
IFVDKSGPKKVIETIEHARHVLQDGTSLVVFPEGARTFTGHMGYFKKGAFQLADDLQLPV
EEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHCHHHHHCCCCCCE
VPLTIIGSFNILPRTGGFVSWHPMTLVVHKPIYPQSQGMENIKATMEEAYREIEKDLPEK
EEEEEECCCEECCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
YQGKIDNPDQDR
HCCCCCCCCCCC
>Mature Secondary Structure
MKVLYILYQLFIALPILLVLTILTAIVTIIGSWIGNPHFWGYYPGKIWSQLFCYVLLIPV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
KVVGHPEVLKKTSYVFVANHQGSFDIFLIYGFLGRNFKWMMKKSLRKMPFVGKACEAAGH
HHCCCHHHHHCCCEEEEECCCCCEEEEEEEHHHCCCHHHHHHHHHHHCCCCCHHHHHCCC
IFVDKSGPKKVIETIEHARHVLQDGTSLVVFPEGARTFTGHMGYFKKGAFQLADDLQLPV
EEEECCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHCHHHHHCCCCCCE
VPLTIIGSFNILPRTGGFVSWHPMTLVVHKPIYPQSQGMENIKATMEEAYREIEKDLPEK
EEEEEECCCEECCCCCCEEEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCHH
YQGKIDNPDQDR
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]