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The map label for this gene is rocD [H]

Identifier: 150004782

GI number: 150004782

Start: 2904226

End: 2905461

Strand: Direct

Name: rocD [H]

Synonym: BVU_2244

Alternate gene names: 150004782

Gene position: 2904226-2905461 (Clockwise)

Preceding gene: 150004781

Following gene: 150004783

Centisome position: 56.25

GC content: 46.04

Gene sequence:

>1236_bases
ATGGATGCAAAATTATCGGCAGCTCAATTGATGGAGCTTGAGAACAAACATGGAGCACACAATTATCATCCTGTTCCTGT
GGTATTGGATAAAGGAGAAGGTGTGTTTGTATGGGATGTGGAAGGAAAGAAATATTATGATTTCCTTTCCGCTTATTCGG
CAGTGAACCAAGGACATTGTCATCCGCGTATTATCGATACGTTGGTAAAACAGGCGCGAAAGCTGACTTTGACTTCACGC
GCTTTTTATAACAGCCAGTTGGGACGGTATGAAGAATTTGTCACCCGTTATTTCGGATATGACAAGGTTTTACCGATGAA
TACGGGAGCCGAGGCAGTAGAAACCGCATTGAAGCTTTGCCGCAAATGGGCGTATGAAGTAAAAAAGCTTCCCAAGGATA
CGGCGGAAATCGTTGTATGCCGGAATAATTTTCATGGGCGTACTACCACTATCGTTTCTTTCTCCATTGATCCGGACGCT
TACAATAACTACGGACCTTTTACCCCCGGCTTTGTCGTGATTCCCTACAATGATGCCGAAGCATTGGCGAAAGTGCTGGA
CGAACATCCTCATGTGGCCGGATTCCTGGTTGAGCCCATTCAGGGAGAGGCAGGTGCTTATGTACCCGATGAGGGATATT
TGAAAAAATGTTACGACTTGTGCCGTGCCCACAATGTACTTTTTATAGCCGATGAAGTGCAGACCGGCATTGCCCGTACA
GGTAAATTGCTGGCTTGTGACTATGAGAATGTTCATCCGGATATCTTGATTTTGGGAAAGGCTTTATCGGGTGGGGCCTG
TCCTGTTTCTGCGGTATTATCATGCAATGAAGTGATGGATGTTATCCGTCCGGGGCAACATGGCTCCACTTTTGGCGGAA
ATCCTATTGCTGCGGCAGTGGCTGTTACGGCGCTTGAGGTAGTACGGGACGAACAGTTGGCGGACAGGGCATACAGGCTG
GGACTGATATTCCGGGAAGAGATGAGAAAACTGTGCGAAACATCTCGTGTGGCTTCTTTGGTCCGGGGCAAGGGATTGCT
GAATGCGTTGATAATCAATAATGATGAAACGAAGGATTTGGCGTGGGAGATTTGCTTGAAATTGGCCGAAAACGGTTTGC
TGGCCAAACCGACACATACGAATATTATTCGTTTTGCTCCGCCATTGGTGATTACAGAGGAACAATTAAAGGAGTGTATC
GAAATTATAAAGAAGACGATTGCTTTGTTTGAATAA

Upstream 100 bases:

>100_bases
TGCCCATCCCTACCATTGAAACGCTGGGAGGAGGAAGTGCCCGTTGCATGATGGCGGAAATATTCTTGAAGAAAGAAAAA
CATTAAATAATAAAAAGCTT

Downstream 100 bases:

>100_bases
AGGATTTTTTTATCCTGTCTTTTAGGGGTGGATTCAATCTGCCCCTAAAATCGTTTTCACTGATACCCACCTGTTTGTGA
CGCTTCATCTTTCATTGTTC

Product: ornithine/acetylornithine aminotransferase

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDAKLSAAQLMELENKHGAHNYHPVPVVLDKGEGVFVWDVEGKKYYDFLSAYSAVNQGHCHPRIIDTLVKQARKLTLTSR
AFYNSQLGRYEEFVTRYFGYDKVLPMNTGAEAVETALKLCRKWAYEVKKLPKDTAEIVVCRNNFHGRTTTIVSFSIDPDA
YNNYGPFTPGFVVIPYNDAEALAKVLDEHPHVAGFLVEPIQGEAGAYVPDEGYLKKCYDLCRAHNVLFIADEVQTGIART
GKLLACDYENVHPDILILGKALSGGACPVSAVLSCNEVMDVIRPGQHGSTFGGNPIAAAVAVTALEVVRDEQLADRAYRL
GLIFREEMRKLCETSRVASLVRGKGLLNALIINNDETKDLAWEICLKLAENGLLAKPTHTNIIRFAPPLVITEEQLKECI
EIIKKTIALFE

Sequences:

>Translated_411_residues
MDAKLSAAQLMELENKHGAHNYHPVPVVLDKGEGVFVWDVEGKKYYDFLSAYSAVNQGHCHPRIIDTLVKQARKLTLTSR
AFYNSQLGRYEEFVTRYFGYDKVLPMNTGAEAVETALKLCRKWAYEVKKLPKDTAEIVVCRNNFHGRTTTIVSFSIDPDA
YNNYGPFTPGFVVIPYNDAEALAKVLDEHPHVAGFLVEPIQGEAGAYVPDEGYLKKCYDLCRAHNVLFIADEVQTGIART
GKLLACDYENVHPDILILGKALSGGACPVSAVLSCNEVMDVIRPGQHGSTFGGNPIAAAVAVTALEVVRDEQLADRAYRL
GLIFREEMRKLCETSRVASLVRGKGLLNALIINNDETKDLAWEICLKLAENGLLAKPTHTNIIRFAPPLVITEEQLKECI
EIIKKTIALFE
>Mature_411_residues
MDAKLSAAQLMELENKHGAHNYHPVPVVLDKGEGVFVWDVEGKKYYDFLSAYSAVNQGHCHPRIIDTLVKQARKLTLTSR
AFYNSQLGRYEEFVTRYFGYDKVLPMNTGAEAVETALKLCRKWAYEVKKLPKDTAEIVVCRNNFHGRTTTIVSFSIDPDA
YNNYGPFTPGFVVIPYNDAEALAKVLDEHPHVAGFLVEPIQGEAGAYVPDEGYLKKCYDLCRAHNVLFIADEVQTGIART
GKLLACDYENVHPDILILGKALSGGACPVSAVLSCNEVMDVIRPGQHGSTFGGNPIAAAVAVTALEVVRDEQLADRAYRL
GLIFREEMRKLCETSRVASLVRGKGLLNALIINNDETKDLAWEICLKLAENGLLAKPTHTNIIRFAPPLVITEEQLKECI
EIIKKTIALFE

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=406, Percent_Identity=61.0837438423645, Blast_Score=514, Evalue=1e-146,
Organism=Homo sapiens, GI284507298, Length=306, Percent_Identity=60.4575163398693, Blast_Score=365, Evalue=1e-101,
Organism=Homo sapiens, GI13994255, Length=437, Percent_Identity=26.5446224256293, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI37574042, Length=429, Percent_Identity=24.9417249417249, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI226442709, Length=397, Percent_Identity=25.4408060453401, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=25.2403846153846, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI226442705, Length=429, Percent_Identity=24.009324009324, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1789759, Length=390, Percent_Identity=34.8717948717949, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=35, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI145693181, Length=386, Percent_Identity=32.3834196891192, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1789016, Length=405, Percent_Identity=30.6172839506173, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787560, Length=405, Percent_Identity=30.3703703703704, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1786991, Length=428, Percent_Identity=25.9345794392523, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786349, Length=346, Percent_Identity=26.0115606936416, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=406, Percent_Identity=55.6650246305419, Blast_Score=473, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI25144274, Length=283, Percent_Identity=51.9434628975265, Blast_Score=290, Evalue=7e-79,
Organism=Caenorhabditis elegans, GI71981843, Length=186, Percent_Identity=56.4516129032258, Blast_Score=238, Evalue=5e-63,
Organism=Caenorhabditis elegans, GI32564660, Length=442, Percent_Identity=28.2805429864253, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=27.3563218390805, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17541228, Length=432, Percent_Identity=24.0740740740741, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=52.8436018957346, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=30.4785894206549, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6324386, Length=471, Percent_Identity=25.6900212314225, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321456, Length=429, Percent_Identity=22.1445221445221, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21357415, Length=394, Percent_Identity=63.7055837563452, Blast_Score=523, Evalue=1e-148,
Organism=Drosophila melanogaster, GI28574759, Length=435, Percent_Identity=27.816091954023, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI161085790, Length=435, Percent_Identity=27.3563218390805, Blast_Score=158, Evalue=8e-39,
Organism=Drosophila melanogaster, GI21356575, Length=438, Percent_Identity=26.2557077625571, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 45586; Mature: 45586

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKLSAAQLMELENKHGAHNYHPVPVVLDKGEGVFVWDVEGKKYYDFLSAYSAVNQGHC
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCC
HPRIIDTLVKQARKLTLTSRAFYNSQLGRYEEFVTRYFGYDKVLPMNTGAEAVETALKLC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
RKWAYEVKKLPKDTAEIVVCRNNFHGRTTTIVSFSIDPDAYNNYGPFTPGFVVIPYNDAE
HHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCHH
ALAKVLDEHPHVAGFLVEPIQGEAGAYVPDEGYLKKCYDLCRAHNVLFIADEVQTGIART
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHC
GKLLACDYENVHPDILILGKALSGGACPVSAVLSCNEVMDVIRPGQHGSTFGGNPIAAAV
CCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AVTALEVVRDEQLADRAYRLGLIFREEMRKLCETSRVASLVRGKGLLNALIINNDETKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
AWEICLKLAENGLLAKPTHTNIIRFAPPLVITEEQLKECIEIIKKTIALFE
HHHHHHHHHCCCCEECCCCCCEEEECCCEEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAKLSAAQLMELENKHGAHNYHPVPVVLDKGEGVFVWDVEGKKYYDFLSAYSAVNQGHC
CCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHHHHHHHHHCCCCC
HPRIIDTLVKQARKLTLTSRAFYNSQLGRYEEFVTRYFGYDKVLPMNTGAEAVETALKLC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHH
RKWAYEVKKLPKDTAEIVVCRNNFHGRTTTIVSFSIDPDAYNNYGPFTPGFVVIPYNDAE
HHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCCHH
ALAKVLDEHPHVAGFLVEPIQGEAGAYVPDEGYLKKCYDLCRAHNVLFIADEVQTGIART
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHHC
GKLLACDYENVHPDILILGKALSGGACPVSAVLSCNEVMDVIRPGQHGSTFGGNPIAAAV
CCEEEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
AVTALEVVRDEQLADRAYRLGLIFREEMRKLCETSRVASLVRGKGLLNALIINNDETKDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
AWEICLKLAENGLLAKPTHTNIIRFAPPLVITEEQLKECIEIIKKTIALFE
HHHHHHHHHCCCCEECCCCCCEEEECCCEEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA