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The map label for this gene is arcB [H]

Identifier: 150004703

GI number: 150004703

Start: 2787645

End: 2791712

Strand: Reverse

Name: arcB [H]

Synonym: BVU_2164

Alternate gene names: 150004703

Gene position: 2791712-2787645 (Counterclockwise)

Preceding gene: 150004725

Following gene: 150004695

Centisome position: 54.07

GC content: 42.16

Gene sequence:

>4068_bases
ATGAAAAAAGTACTAATACTATTATTTCTTACAATTTCATGTATACCCATCATCGCACAGTCTGACTACTTGTTTAAGAA
CATCAGTAGTCGCGATGGGTTATCGAATGATTTTGTACGGGATATGGACGTGGACGGAAAAGGGTTTATTTGGATTGCCA
CCGAAGAGGGACTGAACCGATGGACTGGCAACGGAAATACCATATACCGGGAAAACAACTCCGGATTGGCAAGCAATGAA
TTGACAACCGTGTACTATGATGCGAAGAGCAATAGCGTATGGGCAGGCTCCAGACAAAAAGGCATAAGCATATTCGACTG
CCATACATCGCAATTCAGCCACCTGAGTACCAAAGAAGGACTTGCCAGTGATGCTATCACAGATATCATGCCTGCTGGTG
ATGAAGGTTTATGGATTACTCATGTGGATAACGGAATAAGTTATTACAACCGAAATACGCACAAGATATATGTCTATAAT
TCTTCTACACTATCAGGATTGAAAGACTGCAATCGTTGTTGCAGAGATGACAACAACGGTTATTTGTATGTAGGACATAT
TACTGAAGGGATGAGCATAATCAACCTGAAAAATAAAACGGTGAAAAAATTCTATCATGATGCCCAAAATCCCCAAAGTT
TGCCAGGAAACAATGTACGAAGCATTTACATAGACCATAAAAAAAATATATGGGTAGGGACAAATGGTGGGCTTGCATTA
TTTAATCCGATGACAGAAGAGTTTACCTCCTTTCGCCATGAAGACGACAATCTCCAATCTTTGGTTGGAGACAATGTACA
TCATATCACGGAAACAACAAACAATGTATTGTGGATAGCCTCGGATTTAGGAGGAATCAGCACACTCGACTTAAACAATT
TTGAGCTAAAGAGACAGGAAGACCAATTACACCTTGAGAACATCACTCACATCAATAGCGGACTTTCATCCCCCAACACG
CGTGTCATAATGCAGGATAAATTCGGCCATATCTGGATAGGTAACCATAGTACTGGCGTTGACTTCATAGAGAACAACCG
CCCCCTTTTCCATACCCTGCCCTTCTATAGTGAAAAGGATGGAGTGAAAACACCCAGCCGAGTGTATAGCATAGAAGCGA
ATAGCGGAGGGGAAATATGGCTGGGAGGAGAAAATACGTTAACCTGCTGGCAGGGCAACAAAGTAAAAAAGCAATGGAAT
GTTTCTTCACACTTGTCACATGCTTATTCCGTTATTTATAGTATGAAACAAGACAGCCAAGGTAGACTTTGGATGGGTAT
TGATGACGAAGGAGTACTACGCTATGATCCCAAGAATGATACTTTCAAGCGTATTGATTTGGGTATGGAGAATATAGATG
TACGCACTTTTTACGAAGATGAACAAGGACAAATGTGGATAGGAAGTGAGGAAGGAGTCTATATCAGCCACCATGATAGC
ATCCAAAGATGGAATGTACCGGAGTGGAAACGGTGGAATCCGATTGCATTCGCTCTTATGCAAGATAAACAACGAAAAAT
ATGGATAGGGACATTGGGAGTAGGAATCTACGTTGTTGATGCAAACCATAAACAATTGACAAGACTGTATGACGGCAATC
GCCTGCGTACCAATAACATCAATCAAATTTACCGAGACCGGGATGACGGACTGTGGATAGCTACATATAATGGACTGGTC
TATGTGAAAGATACCGACCAACCGGAACAGACTATATTATACGATGAGGCGTATGGACTTGCCGACAACCATATCCGAGC
CATCCAGCAAGACAAACTGGGTAATATTTGGGTAAGTACCTATACGGGGATTGCCTGTTTTAATGTTTACCGCCAGAAAT
TCTACAATTATGATTATCACAACGGGATACCTGCAGGAGGCTTTATCGAAGGCTCGGCAACTATCTTGCCGGACGGAACT
ATCTGCTTCGGTTCTTTACATGGTGTCTGTTCTTTCAATCCACAACTTATCAATAATACGGATATTGTCTCCCCTATCCA
ACTCATCGCTTGCGAAAGTTTTGACCGTAAGGTAATAAACAGAAAAGCAGAAACAACAGTTCCCAATGACAAAGGGGTAA
TCAGCCTGCCTTATTACCGCAATACATTCCGCTTTTTATTCACCGTACCAGATTACGCACAAGAAGGTCTAGTTGAGTAT
GCCTACCAAATGGAGGGACTGGACAGAACGTGGTATGATACCGAAGGAGAACAACAAATAACCTTCCGAAACATAGATCC
GGGTAAATATATCTTCCGAGTTAAAGCACGGCTGAAAAATGGTGAATGGGATGAAAAAAATACTGCATCCATACACATTG
TCATTAATCCGCCGATTTGGGCAACATGGTATGCCAAATCATTATATACCTTATTAATATTGTGCATTATTTATCTCATC
TTCCGTTCATACAAAAAAAGACTGCTGCTGAAGAGTTCTTTAAAGGTGGAGAAAAACTCGCTGGAGATGGAAAAGAGAAA
TCGGCAGAAAGAACAAGAACTGCACAATGAACGGCTTCGCTTCTATACAAATATCGCACATGAATTACGTACTCCGCTTA
CGCTGATTATCGGTCCGTTGGAGGATTTAAAGGATAACAAAGGCATACCCGCCGCTTTCCGTACAAAAATACAGACCATA
TACCGCAGTGCCGTGCAACTGCTCAATCTTATCAACCAACTGATGGAATTCCGCAAGACCGAAACTCAAAACAGACAACT
GACTGTGGGTAAAGGCAACCTGAGCAATCTGATTACAGAAATAGGATTGAGATATAAGGAGCTGAATCAAAATGAGCATG
TAAGAATCAATGTCAAAGTGGAACCTGTACAGGAAAATATCTATTTCGATGCGGATATCATCACGATCATACTTAACAAT
CTGTTGTCCAATGCCATCAAATACACTCGGGCAGGACATATCACACTCTCCATGCACCGAATAAAGGCAAATGGCATAAG
CTATGTAGAAATGATAGTGGCAGATACTGGCTATGGAATTGACGCAGAGTCCTTGCCGCACATTTACGACCGATACTATC
AAGCGAAGGGCAAGCACCAGGCTTCGGGTACCGGTATCGGGCTGGCATTGGTGAAGTCGCTCGTTGATTTGCACCACGGT
TCACTGGAGGTGGAAAGTGCCGTGGAGAAAGGAACGACTTTCCGCTTCCGCATACAAACCGATTACAATTACCCCGAGGC
ATTGCACAAGGAAGAAAAAGTGGTTACTGTTGTAAAGGAAATGGCAGAAGATGCCGAACCGGAAAGTGCATTCCCTATTC
TGTTGGTGGTGGAAGACAATGCTGACATCCGGGAATATATAGCCAATGAATTACAAGATACATATAAAATATTGCAAGCC
AATAACGGAAAGGAGGGTCTGATTTTGGCGTTAAGATACACTCCAAATATTATAGTGAGTGACATCATGATGCCGGAAAT
GGATGGCATAGCCATGTGCAAGGGCATCAAGGAGAACATGAATACCAGCCACATCCCTGTCATCCTCCTTACAGCCAAGG
ACTCCATACAAGATAAAGAAGAGGGGTACGACAGTGGAGCCGACTCTTACTTGACCAAACCTTTCAGTGCGAAACTATTG
AGGAGTCGCATCAAGAACTTGTTGGAGATGCGGAAACGCCTTGCCCGGCAAATTGTGGAAAATGTTCCGTCTACGGTGGT
CAAGAACACCGAAAAGCGACAATCTACTTCATCCCCTCATCCGCAATTGAACAGATTGGACGAAGCCTTTCTCTCTAAAT
TGACTTCATTGATAGAAGATAATCTGGATGTAGAGAAAATAGACACCGCTTTTATGATTGATTGTATGAACATGAGTTAT
TCTGCCTTCTATCGTAAAGTAAAAGCTTTGACAGAACTTAGTCCCAATGAATTTGTTCGAAAGATTAAGCTAAGAAATAG
TGCACATCTATTACTTACAGGAGAACATAATGTGTCAGAAGCCGCCTCAATGACCGGCTTTAACAATATGGCACACTTCC
GCGATTGTTTCAAAAAAGAATATGGCATTCCTCCATCCGAATATCAGAAACGATATAGACAGGGGTAA

Upstream 100 bases:

>100_bases
TGTTCCTTTCACCATGAAACATTATCTTTGTCATTGTCAAAGCAATATTTGTCTACATAAAAAGAAAAGATAATAAAAAA
ATAGCCTAATCGAATATATT

Downstream 100 bases:

>100_bases
ACTTGATACCGGAGGAGGGGCAGAAAGAAGTTAGGAAGTTAAGCCGATACATTGCTGCCAATATATTGTCTATTGACTTT
AACTTCTAAGCTCGCCCGGA

Product: two-component system sensor histidine kinase/response regulator, hybrid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1355; Mature: 1355

Protein sequence:

>1355_residues
MKKVLILLFLTISCIPIIAQSDYLFKNISSRDGLSNDFVRDMDVDGKGFIWIATEEGLNRWTGNGNTIYRENNSGLASNE
LTTVYYDAKSNSVWAGSRQKGISIFDCHTSQFSHLSTKEGLASDAITDIMPAGDEGLWITHVDNGISYYNRNTHKIYVYN
SSTLSGLKDCNRCCRDDNNGYLYVGHITEGMSIINLKNKTVKKFYHDAQNPQSLPGNNVRSIYIDHKKNIWVGTNGGLAL
FNPMTEEFTSFRHEDDNLQSLVGDNVHHITETTNNVLWIASDLGGISTLDLNNFELKRQEDQLHLENITHINSGLSSPNT
RVIMQDKFGHIWIGNHSTGVDFIENNRPLFHTLPFYSEKDGVKTPSRVYSIEANSGGEIWLGGENTLTCWQGNKVKKQWN
VSSHLSHAYSVIYSMKQDSQGRLWMGIDDEGVLRYDPKNDTFKRIDLGMENIDVRTFYEDEQGQMWIGSEEGVYISHHDS
IQRWNVPEWKRWNPIAFALMQDKQRKIWIGTLGVGIYVVDANHKQLTRLYDGNRLRTNNINQIYRDRDDGLWIATYNGLV
YVKDTDQPEQTILYDEAYGLADNHIRAIQQDKLGNIWVSTYTGIACFNVYRQKFYNYDYHNGIPAGGFIEGSATILPDGT
ICFGSLHGVCSFNPQLINNTDIVSPIQLIACESFDRKVINRKAETTVPNDKGVISLPYYRNTFRFLFTVPDYAQEGLVEY
AYQMEGLDRTWYDTEGEQQITFRNIDPGKYIFRVKARLKNGEWDEKNTASIHIVINPPIWATWYAKSLYTLLILCIIYLI
FRSYKKRLLLKSSLKVEKNSLEMEKRNRQKEQELHNERLRFYTNIAHELRTPLTLIIGPLEDLKDNKGIPAAFRTKIQTI
YRSAVQLLNLINQLMEFRKTETQNRQLTVGKGNLSNLITEIGLRYKELNQNEHVRINVKVEPVQENIYFDADIITIILNN
LLSNAIKYTRAGHITLSMHRIKANGISYVEMIVADTGYGIDAESLPHIYDRYYQAKGKHQASGTGIGLALVKSLVDLHHG
SLEVESAVEKGTTFRFRIQTDYNYPEALHKEEKVVTVVKEMAEDAEPESAFPILLVVEDNADIREYIANELQDTYKILQA
NNGKEGLILALRYTPNIIVSDIMMPEMDGIAMCKGIKENMNTSHIPVILLTAKDSIQDKEEGYDSGADSYLTKPFSAKLL
RSRIKNLLEMRKRLARQIVENVPSTVVKNTEKRQSTSSPHPQLNRLDEAFLSKLTSLIEDNLDVEKIDTAFMIDCMNMSY
SAFYRKVKALTELSPNEFVRKIKLRNSAHLLLTGEHNVSEAASMTGFNNMAHFRDCFKKEYGIPPSEYQKRYRQG

Sequences:

>Translated_1355_residues
MKKVLILLFLTISCIPIIAQSDYLFKNISSRDGLSNDFVRDMDVDGKGFIWIATEEGLNRWTGNGNTIYRENNSGLASNE
LTTVYYDAKSNSVWAGSRQKGISIFDCHTSQFSHLSTKEGLASDAITDIMPAGDEGLWITHVDNGISYYNRNTHKIYVYN
SSTLSGLKDCNRCCRDDNNGYLYVGHITEGMSIINLKNKTVKKFYHDAQNPQSLPGNNVRSIYIDHKKNIWVGTNGGLAL
FNPMTEEFTSFRHEDDNLQSLVGDNVHHITETTNNVLWIASDLGGISTLDLNNFELKRQEDQLHLENITHINSGLSSPNT
RVIMQDKFGHIWIGNHSTGVDFIENNRPLFHTLPFYSEKDGVKTPSRVYSIEANSGGEIWLGGENTLTCWQGNKVKKQWN
VSSHLSHAYSVIYSMKQDSQGRLWMGIDDEGVLRYDPKNDTFKRIDLGMENIDVRTFYEDEQGQMWIGSEEGVYISHHDS
IQRWNVPEWKRWNPIAFALMQDKQRKIWIGTLGVGIYVVDANHKQLTRLYDGNRLRTNNINQIYRDRDDGLWIATYNGLV
YVKDTDQPEQTILYDEAYGLADNHIRAIQQDKLGNIWVSTYTGIACFNVYRQKFYNYDYHNGIPAGGFIEGSATILPDGT
ICFGSLHGVCSFNPQLINNTDIVSPIQLIACESFDRKVINRKAETTVPNDKGVISLPYYRNTFRFLFTVPDYAQEGLVEY
AYQMEGLDRTWYDTEGEQQITFRNIDPGKYIFRVKARLKNGEWDEKNTASIHIVINPPIWATWYAKSLYTLLILCIIYLI
FRSYKKRLLLKSSLKVEKNSLEMEKRNRQKEQELHNERLRFYTNIAHELRTPLTLIIGPLEDLKDNKGIPAAFRTKIQTI
YRSAVQLLNLINQLMEFRKTETQNRQLTVGKGNLSNLITEIGLRYKELNQNEHVRINVKVEPVQENIYFDADIITIILNN
LLSNAIKYTRAGHITLSMHRIKANGISYVEMIVADTGYGIDAESLPHIYDRYYQAKGKHQASGTGIGLALVKSLVDLHHG
SLEVESAVEKGTTFRFRIQTDYNYPEALHKEEKVVTVVKEMAEDAEPESAFPILLVVEDNADIREYIANELQDTYKILQA
NNGKEGLILALRYTPNIIVSDIMMPEMDGIAMCKGIKENMNTSHIPVILLTAKDSIQDKEEGYDSGADSYLTKPFSAKLL
RSRIKNLLEMRKRLARQIVENVPSTVVKNTEKRQSTSSPHPQLNRLDEAFLSKLTSLIEDNLDVEKIDTAFMIDCMNMSY
SAFYRKVKALTELSPNEFVRKIKLRNSAHLLLTGEHNVSEAASMTGFNNMAHFRDCFKKEYGIPPSEYQKRYRQG
>Mature_1355_residues
MKKVLILLFLTISCIPIIAQSDYLFKNISSRDGLSNDFVRDMDVDGKGFIWIATEEGLNRWTGNGNTIYRENNSGLASNE
LTTVYYDAKSNSVWAGSRQKGISIFDCHTSQFSHLSTKEGLASDAITDIMPAGDEGLWITHVDNGISYYNRNTHKIYVYN
SSTLSGLKDCNRCCRDDNNGYLYVGHITEGMSIINLKNKTVKKFYHDAQNPQSLPGNNVRSIYIDHKKNIWVGTNGGLAL
FNPMTEEFTSFRHEDDNLQSLVGDNVHHITETTNNVLWIASDLGGISTLDLNNFELKRQEDQLHLENITHINSGLSSPNT
RVIMQDKFGHIWIGNHSTGVDFIENNRPLFHTLPFYSEKDGVKTPSRVYSIEANSGGEIWLGGENTLTCWQGNKVKKQWN
VSSHLSHAYSVIYSMKQDSQGRLWMGIDDEGVLRYDPKNDTFKRIDLGMENIDVRTFYEDEQGQMWIGSEEGVYISHHDS
IQRWNVPEWKRWNPIAFALMQDKQRKIWIGTLGVGIYVVDANHKQLTRLYDGNRLRTNNINQIYRDRDDGLWIATYNGLV
YVKDTDQPEQTILYDEAYGLADNHIRAIQQDKLGNIWVSTYTGIACFNVYRQKFYNYDYHNGIPAGGFIEGSATILPDGT
ICFGSLHGVCSFNPQLINNTDIVSPIQLIACESFDRKVINRKAETTVPNDKGVISLPYYRNTFRFLFTVPDYAQEGLVEY
AYQMEGLDRTWYDTEGEQQITFRNIDPGKYIFRVKARLKNGEWDEKNTASIHIVINPPIWATWYAKSLYTLLILCIIYLI
FRSYKKRLLLKSSLKVEKNSLEMEKRNRQKEQELHNERLRFYTNIAHELRTPLTLIIGPLEDLKDNKGIPAAFRTKIQTI
YRSAVQLLNLINQLMEFRKTETQNRQLTVGKGNLSNLITEIGLRYKELNQNEHVRINVKVEPVQENIYFDADIITIILNN
LLSNAIKYTRAGHITLSMHRIKANGISYVEMIVADTGYGIDAESLPHIYDRYYQAKGKHQASGTGIGLALVKSLVDLHHG
SLEVESAVEKGTTFRFRIQTDYNYPEALHKEEKVVTVVKEMAEDAEPESAFPILLVVEDNADIREYIANELQDTYKILQA
NNGKEGLILALRYTPNIIVSDIMMPEMDGIAMCKGIKENMNTSHIPVILLTAKDSIQDKEEGYDSGADSYLTKPFSAKLL
RSRIKNLLEMRKRLARQIVENVPSTVVKNTEKRQSTSSPHPQLNRLDEAFLSKLTSLIEDNLDVEKIDTAFMIDCMNMSY
SAFYRKVKALTELSPNEFVRKIKLRNSAHLLLTGEHNVSEAASMTGFNNMAHFRDCFKKEYGIPPSEYQKRYRQG

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=389, Percent_Identity=27.7634961439589, Blast_Score=136, Evalue=1e-32,
Organism=Escherichia coli, GI1788713, Length=393, Percent_Identity=25.6997455470738, Blast_Score=131, Evalue=3e-31,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=29.8850574712644, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=29.7520661157025, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI87082012, Length=117, Percent_Identity=39.3162393162393, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI87081816, Length=355, Percent_Identity=25.3521126760563, Blast_Score=85, Evalue=3e-17,
Organism=Escherichia coli, GI1786599, Length=130, Percent_Identity=36.9230769230769, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1787375, Length=134, Percent_Identity=32.8358208955224, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786783, Length=224, Percent_Identity=29.4642857142857, Blast_Score=78, Evalue=4e-15,
Organism=Escherichia coli, GI1786911, Length=136, Percent_Identity=32.3529411764706, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788393, Length=211, Percent_Identity=25.1184834123223, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1786912, Length=260, Percent_Identity=26.1538461538462, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1790436, Length=272, Percent_Identity=26.1029411764706, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786784, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=225, Percent_Identity=25.3333333333333, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1788394, Length=134, Percent_Identity=29.1044776119403, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=30.1724137931034, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=31.3559322033898, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=27.2321428571429, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790551, Length=233, Percent_Identity=28.3261802575107, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=25.9414225941423, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 154980; Mature: 154980

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLILLFLTISCIPIIAQSDYLFKNISSRDGLSNDFVRDMDVDGKGFIWIATEEGLNR
CCHHHHHHHHHHHHHHHEECCCHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCHH
WTGNGNTIYRENNSGLASNELTTVYYDAKSNSVWAGSRQKGISIFDCHTSQFSHLSTKEG
CCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCHHHCCCCCCC
LASDAITDIMPAGDEGLWITHVDNGISYYNRNTHKIYVYNSSTLSGLKDCNRCCRDDNNG
CHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
YLYVGHITEGMSIINLKNKTVKKFYHDAQNPQSLPGNNVRSIYIDHKKNIWVGTNGGLAL
EEEEEEECCCEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEECCCCEEE
FNPMTEEFTSFRHEDDNLQSLVGDNVHHITETTNNVLWIASDLGGISTLDLNNFELKRQE
ECCHHHHHHHHCCCCCHHHHHHCCCHHEEECCCCCEEEEEECCCCEEEEECCCCEECCCC
DQLHLENITHINSGLSSPNTRVIMQDKFGHIWIGNHSTGVDFIENNRPLFHTLPFYSEKD
CHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCCCEEECCCCEEEECCCCCCCC
GVKTPSRVYSIEANSGGEIWLGGENTLTCWQGNKVKKQWNVSSHLSHAYSVIYSMKQDSQ
CCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCC
GRLWMGIDDEGVLRYDPKNDTFKRIDLGMENIDVRTFYEDEQGQMWIGSEEGVYISHHDS
CCEEEECCCCCCEEECCCCCCHHEEECCCCCCEEEEEEECCCCCEEECCCCCEEEEECCC
IQRWNVPEWKRWNPIAFALMQDKQRKIWIGTLGVGIYVVDANHKQLTRLYDGNRLRTNNI
CCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECEEEEEEECCHHHHHHHHCCCEEECCCC
NQIYRDRDDGLWIATYNGLVYVKDTDQPEQTILYDEAYGLADNHIRAIQQDKLGNIWVST
HHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEH
YTGIACFNVYRQKFYNYDYHNGIPAGGFIEGSATILPDGTICFGSLHGVCSFNPQLINNT
HCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEECCCCCEEEECCCCEEECCCCEECCC
DIVSPIQLIACESFDRKVINRKAETTVPNDKGVISLPYYRNTFRFLFTVPDYAQEGLVEY
CCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHH
AYQMEGLDRTWYDTEGEQQITFRNIDPGKYIFRVKARLKNGEWDEKNTASIHIVINPPIW
HHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCC
ATWYAKSLYTLLILCIIYLIFRSYKKRLLLKSSLKVEKNSLEMEKRNRQKEQELHNERLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FYTNIAHELRTPLTLIIGPLEDLKDNKGIPAAFRTKIQTIYRSAVQLLNLINQLMEFRKT
HHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ETQNRQLTVGKGNLSNLITEIGLRYKELNQNEHVRINVKVEPVQENIYFDADIITIILNN
CCCCCEEEEECCCHHHHHHHHCCHHHHCCCCCEEEEEEEEEEECCCEEECHHHHHHHHHH
LLSNAIKYTRAGHITLSMHRIKANGISYVEMIVADTGYGIDAESLPHIYDRYYQAKGKHQ
HHHHHHHHHCCCEEEEEEEEEECCCCEEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCC
ASGTGIGLALVKSLVDLHHGSLEVESAVEKGTTFRFRIQTDYNYPEALHKEEKVVTVVKE
CCCCCHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEEEECCCCHHHHCCHHHHHHHHHH
MAEDAEPESAFPILLVVEDNADIREYIANELQDTYKILQANNGKEGLILALRYTPNIIVS
HHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEH
DIMMPEMDGIAMCKGIKENMNTSHIPVILLTAKDSIQDKEEGYDSGADSYLTKPFSAKLL
HHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCHHHCCCHHHHHH
RSRIKNLLEMRKRLARQIVENVPSTVVKNTEKRQSTSSPHPQLNRLDEAFLSKLTSLIED
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
NLDVEKIDTAFMIDCMNMSYSAFYRKVKALTELSPNEFVRKIKLRNSAHLLLTGEHNVSE
CCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCHHH
AASMTGFNNMAHFRDCFKKEYGIPPSEYQKRYRQG
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKKVLILLFLTISCIPIIAQSDYLFKNISSRDGLSNDFVRDMDVDGKGFIWIATEEGLNR
CCHHHHHHHHHHHHHHHEECCCHHHHCCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCHH
WTGNGNTIYRENNSGLASNELTTVYYDAKSNSVWAGSRQKGISIFDCHTSQFSHLSTKEG
CCCCCCEEEEECCCCCCCCCEEEEEEECCCCCEECCCCCCCCEEEEECCCHHHCCCCCCC
LASDAITDIMPAGDEGLWITHVDNGISYYNRNTHKIYVYNSSTLSGLKDCNRCCRDDNNG
CHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCC
YLYVGHITEGMSIINLKNKTVKKFYHDAQNPQSLPGNNVRSIYIDHKKNIWVGTNGGLAL
EEEEEEECCCEEEEEECHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCEEEECCCCEEE
FNPMTEEFTSFRHEDDNLQSLVGDNVHHITETTNNVLWIASDLGGISTLDLNNFELKRQE
ECCHHHHHHHHCCCCCHHHHHHCCCHHEEECCCCCEEEEEECCCCEEEEECCCCEECCCC
DQLHLENITHINSGLSSPNTRVIMQDKFGHIWIGNHSTGVDFIENNRPLFHTLPFYSEKD
CHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEECCCCCCCCEEECCCCEEEECCCCCCCC
GVKTPSRVYSIEANSGGEIWLGGENTLTCWQGNKVKKQWNVSSHLSHAYSVIYSMKQDSQ
CCCCCCCEEEEEECCCCEEEECCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCC
GRLWMGIDDEGVLRYDPKNDTFKRIDLGMENIDVRTFYEDEQGQMWIGSEEGVYISHHDS
CCEEEECCCCCCEEECCCCCCHHEEECCCCCCEEEEEEECCCCCEEECCCCCEEEEECCC
IQRWNVPEWKRWNPIAFALMQDKQRKIWIGTLGVGIYVVDANHKQLTRLYDGNRLRTNNI
CCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECEEEEEEECCHHHHHHHHCCCEEECCCC
NQIYRDRDDGLWIATYNGLVYVKDTDQPEQTILYDEAYGLADNHIRAIQQDKLGNIWVST
HHHHHCCCCCEEEEEECCEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCEEEEH
YTGIACFNVYRQKFYNYDYHNGIPAGGFIEGSATILPDGTICFGSLHGVCSFNPQLINNT
HCHHHHHHHHHHHHCCCCCCCCCCCCCEECCCEEECCCCCEEEECCCCEEECCCCEECCC
DIVSPIQLIACESFDRKVINRKAETTVPNDKGVISLPYYRNTFRFLFTVPDYAQEGLVEY
CCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEECCCHHHHHHHHH
AYQMEGLDRTWYDTEGEQQITFRNIDPGKYIFRVKARLKNGEWDEKNTASIHIVINPPIW
HHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCC
ATWYAKSLYTLLILCIIYLIFRSYKKRLLLKSSLKVEKNSLEMEKRNRQKEQELHNERLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
FYTNIAHELRTPLTLIIGPLEDLKDNKGIPAAFRTKIQTIYRSAVQLLNLINQLMEFRKT
HHHHHHHHHCCCEEEEEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ETQNRQLTVGKGNLSNLITEIGLRYKELNQNEHVRINVKVEPVQENIYFDADIITIILNN
CCCCCEEEEECCCHHHHHHHHCCHHHHCCCCCEEEEEEEEEEECCCEEECHHHHHHHHHH
LLSNAIKYTRAGHITLSMHRIKANGISYVEMIVADTGYGIDAESLPHIYDRYYQAKGKHQ
HHHHHHHHHCCCEEEEEEEEEECCCCEEEEEEEECCCCCCCHHCCCHHHHHHHHHCCCCC
ASGTGIGLALVKSLVDLHHGSLEVESAVEKGTTFRFRIQTDYNYPEALHKEEKVVTVVKE
CCCCCHHHHHHHHHHHHCCCCEEHHHHHHCCCEEEEEEEECCCCHHHHCCHHHHHHHHHH
MAEDAEPESAFPILLVVEDNADIREYIANELQDTYKILQANNGKEGLILALRYTPNIIVS
HHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEH
DIMMPEMDGIAMCKGIKENMNTSHIPVILLTAKDSIQDKEEGYDSGADSYLTKPFSAKLL
HHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHCCCCCCCCHHHCCCHHHHHH
RSRIKNLLEMRKRLARQIVENVPSTVVKNTEKRQSTSSPHPQLNRLDEAFLSKLTSLIED
HHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
NLDVEKIDTAFMIDCMNMSYSAFYRKVKALTELSPNEFVRKIKLRNSAHLLLTGEHNVSE
CCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCCCHHH
AASMTGFNNMAHFRDCFKKEYGIPPSEYQKRYRQG
HHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]