Click here to switch to the map view.

The map label for this gene is pepP [H]

Identifier: 150004616

GI number: 150004616

Start: 2687326

End: 2688717

Strand: Reverse

Name: pepP [H]

Synonym: BVU_2073

Alternate gene names: 150004616

Gene position: 2688717-2687326 (Counterclockwise)

Preceding gene: 150004618

Following gene: 150004615

Centisome position: 52.07

GC content: 43.32

Gene sequence:

>1392_bases
ATGTTTGATTCCGCAACTTATCAAAGACGCCGTCAGGCACTTAGAAACAAAGTGCAAAACGGTATTATCCTTATACTAGG
TAATAATGAAGCTCCGGCAAACTATCCGGATAACACATATAAATTCCGTCAGGACAGTTCATTCCTCTACTTCTTCGGTC
ATTCTCACCCCGGATATGCAGGTGTAATAGATATAGAAGCAGGAGAGGATTATTTCTTCGGAAATGATGTAGATATGGAC
GACATTATCTGGATGGGGCCCCAACCCAGTGTGAAAGAGTTGGCTGCACAAGTAGGTATTCAGAAAAGTTTTCCCTTTCC
CCAGCTAAAAGAGGTGGTAGGAAAAGCTATCGCGCAAGGTAGAAAAGTACATTTCCTTCCTCCCTACCGATTCGATAATA
TGATGCTCTTGGAAGACTTAACCGGTATCCGTGCCGCTATAGTAAAGAAATACGCTTCTGTAGAATTGATAAAAGCTGTA
GTTGATTTACGTTCTGTAAAAGAAGCTTGCGAAATAGCAGAAATCGATTTGGCATGTAATATCGGTTATGAAATGCACAC
AGCCGCTATGCGTCTATGTAAACCTGGAATAAAGGAACAATATATCGCCGGAGTACTGGATGGCATCGCCGCTTCTTATG
GAAGCATGACTTCATTTGCCACTATCCTGACCCAACATGGGGAAACATTACATAATCATGACCATAGCCATATATTAGAA
CCAGGACGCATGATGCTGACAGATGCCGGAGCTGAAAGAGTGACAAATTATTGTTCTGACCATACCCGTACCGTACCTGT
GGGAGGCAAATTTGAAGGACGGCAAAAAGATGTGTATAATATTGTATTGGCTTGCCATGATAAAGCATTGGAAATTACTC
GTCCAGGTATAACCTATATGTCTGTACACTTAGAAGTCTGCAAAGTGCTGGTTCAAGGATTAAAAGACCTGGGGCTCATG
AAGGGCAATGTGGAAGAAGCTGTTGCCGCTGGTGCACACGCTTTATTCCTGCCCCATGGATTAGGTCATATGATGGGATT
GGATGTACATGACATGGAAGACCTGGGACAAATTTACGTAGGATATGACGATGAAATCCGTCCTTCTTCCCAGTTCGGGC
TAGCCTCCCTGCGCATGGGACGTCGCTTACAGGAAGGCTTTGTGATTACCGATGAACCGGGCTGCTATTTTATTCCAGCA
TTGATTGACAAATGGAAAGCTGAGAAAATGCATACAGACTTCCTGAACTTTGATGCCATTGAAAAATTCAAAGATTTTGG
AGGCATCCGCCTGGAAGACGATATTCTGATTACTTCGGAAGGCTCCCGTTTCACTGGCGAGAAACGCATCCCTATCACTA
TCGAAGAAGTAGAAACTATCATGAATGAGTAA

Upstream 100 bases:

>100_bases
AATCGATTAAAAAATCAAATAAGCAAATAGTACTTTTAAGATTATAATTATTACATTTGCAACACAGTTCAATAAATTTT
CAATTAAAATAAAGTTAGCC

Downstream 100 bases:

>100_bases
CATAACAAACAAAACTATTATTTCTAAAATGAAAAGATTTACATTATTAGCAGCATTAGGTTTATGCAGTATAAGCCTCT
TTGCACAAGATGCACAAAAA

Product: Xaa-Pro aminopeptidase

Products: NA

Alternate protein names: Aminoacylproline aminopeptidase; Aminopeptidase P II; APP-II; X-Pro aminopeptidase [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MFDSATYQRRRQALRNKVQNGIILILGNNEAPANYPDNTYKFRQDSSFLYFFGHSHPGYAGVIDIEAGEDYFFGNDVDMD
DIIWMGPQPSVKELAAQVGIQKSFPFPQLKEVVGKAIAQGRKVHFLPPYRFDNMMLLEDLTGIRAAIVKKYASVELIKAV
VDLRSVKEACEIAEIDLACNIGYEMHTAAMRLCKPGIKEQYIAGVLDGIAASYGSMTSFATILTQHGETLHNHDHSHILE
PGRMMLTDAGAERVTNYCSDHTRTVPVGGKFEGRQKDVYNIVLACHDKALEITRPGITYMSVHLEVCKVLVQGLKDLGLM
KGNVEEAVAAGAHALFLPHGLGHMMGLDVHDMEDLGQIYVGYDDEIRPSSQFGLASLRMGRRLQEGFVITDEPGCYFIPA
LIDKWKAEKMHTDFLNFDAIEKFKDFGGIRLEDDILITSEGSRFTGEKRIPITIEEVETIMNE

Sequences:

>Translated_463_residues
MFDSATYQRRRQALRNKVQNGIILILGNNEAPANYPDNTYKFRQDSSFLYFFGHSHPGYAGVIDIEAGEDYFFGNDVDMD
DIIWMGPQPSVKELAAQVGIQKSFPFPQLKEVVGKAIAQGRKVHFLPPYRFDNMMLLEDLTGIRAAIVKKYASVELIKAV
VDLRSVKEACEIAEIDLACNIGYEMHTAAMRLCKPGIKEQYIAGVLDGIAASYGSMTSFATILTQHGETLHNHDHSHILE
PGRMMLTDAGAERVTNYCSDHTRTVPVGGKFEGRQKDVYNIVLACHDKALEITRPGITYMSVHLEVCKVLVQGLKDLGLM
KGNVEEAVAAGAHALFLPHGLGHMMGLDVHDMEDLGQIYVGYDDEIRPSSQFGLASLRMGRRLQEGFVITDEPGCYFIPA
LIDKWKAEKMHTDFLNFDAIEKFKDFGGIRLEDDILITSEGSRFTGEKRIPITIEEVETIMNE
>Mature_463_residues
MFDSATYQRRRQALRNKVQNGIILILGNNEAPANYPDNTYKFRQDSSFLYFFGHSHPGYAGVIDIEAGEDYFFGNDVDMD
DIIWMGPQPSVKELAAQVGIQKSFPFPQLKEVVGKAIAQGRKVHFLPPYRFDNMMLLEDLTGIRAAIVKKYASVELIKAV
VDLRSVKEACEIAEIDLACNIGYEMHTAAMRLCKPGIKEQYIAGVLDGIAASYGSMTSFATILTQHGETLHNHDHSHILE
PGRMMLTDAGAERVTNYCSDHTRTVPVGGKFEGRQKDVYNIVLACHDKALEITRPGITYMSVHLEVCKVLVQGLKDLGLM
KGNVEEAVAAGAHALFLPHGLGHMMGLDVHDMEDLGQIYVGYDDEIRPSSQFGLASLRMGRRLQEGFVITDEPGCYFIPA
LIDKWKAEKMHTDFLNFDAIEKFKDFGGIRLEDDILITSEGSRFTGEKRIPITIEEVETIMNE

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI149589008, Length=484, Percent_Identity=30.1652892561983, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI260593663, Length=467, Percent_Identity=29.9785867237687, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI260593665, Length=312, Percent_Identity=33.3333333333333, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI11559925, Length=480, Percent_Identity=25.8333333333333, Blast_Score=135, Evalue=1e-31,
Organism=Escherichia coli, GI1789275, Length=471, Percent_Identity=29.723991507431, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1790282, Length=290, Percent_Identity=31.0344827586207, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788728, Length=298, Percent_Identity=25.503355704698, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17508215, Length=475, Percent_Identity=31.3684210526316, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71989583, Length=390, Percent_Identity=22.5641025641026, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321118, Length=445, Percent_Identity=28.9887640449438, Blast_Score=156, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320922, Length=462, Percent_Identity=23.3766233766234, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357079, Length=463, Percent_Identity=31.1015118790497, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI19920384, Length=420, Percent_Identity=24.2857142857143, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR007865
- InterPro:   IPR001131 [H]

Pfam domain/function: PF05195 AMP_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.11.9 [H]

Molecular weight: Translated: 51735; Mature: 51735

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDSATYQRRRQALRNKVQNGIILILGNNEAPANYPDNTYKFRQDSSFLYFFGHSHPGYA
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCE
GVIDIEAGEDYFFGNDVDMDDIIWMGPQPSVKELAAQVGIQKSFPFPQLKEVVGKAIAQG
EEEEEECCCCEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
RKVHFLPPYRFDNMMLLEDLTGIRAAIVKKYASVELIKAVVDLRSVKEACEIAEIDLACN
CEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
IGYEMHTAAMRLCKPGIKEQYIAGVLDGIAASYGSMTSFATILTQHGETLHNHDHSHILE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCHHHCC
PGRMMLTDAGAERVTNYCSDHTRTVPVGGKFEGRQKDVYNIVLACHDKALEITRPGITYM
CCCEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHEEEEEECCCEEEEECCCCEEE
SVHLEVCKVLVQGLKDLGLMKGNVEEAVAAGAHALFLPHGLGHMMGLDVHDMEDLGQIYV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHCCCCCCHHHCCCEEE
GYDDEIRPSSQFGLASLRMGRRLQEGFVITDEPGCYFIPALIDKWKAEKMHTDFLNFDAI
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHCCHHHH
EKFKDFGGIRLEDDILITSEGSRFTGEKRIPITIEEVETIMNE
HHHHHCCCCEEECCEEEECCCCCCCCCCCCCEEHHHHHHHHCC
>Mature Secondary Structure
MFDSATYQRRRQALRNKVQNGIILILGNNEAPANYPDNTYKFRQDSSFLYFFGHSHPGYA
CCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEECCCCCCE
GVIDIEAGEDYFFGNDVDMDDIIWMGPQPSVKELAAQVGIQKSFPFPQLKEVVGKAIAQG
EEEEEECCCCEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCC
RKVHFLPPYRFDNMMLLEDLTGIRAAIVKKYASVELIKAVVDLRSVKEACEIAEIDLACN
CEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
IGYEMHTAAMRLCKPGIKEQYIAGVLDGIAASYGSMTSFATILTQHGETLHNHDHSHILE
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHCCCCHHHCC
PGRMMLTDAGAERVTNYCSDHTRTVPVGGKFEGRQKDVYNIVLACHDKALEITRPGITYM
CCCEEEECCCHHHHHHHHCCCCEEECCCCCCCCCCHHHHEEEEEECCCEEEEECCCCEEE
SVHLEVCKVLVQGLKDLGLMKGNVEEAVAAGAHALFLPHGLGHMMGLDVHDMEDLGQIYV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHCCCCCCHHHCCCEEE
GYDDEIRPSSQFGLASLRMGRRLQEGFVITDEPGCYFIPALIDKWKAEKMHTDFLNFDAI
CCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCEEHHHHHHHHHHHHHHHHHCCHHHH
EKFKDFGGIRLEDDILITSEGSRFTGEKRIPITIEEVETIMNE
HHHHHCCCCEEECCEEEECCCCCCCCCCCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2659585; 1339425; 9278503; 9520390 [H]