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The map label for this gene is dapL [H]

Identifier: 150004605

GI number: 150004605

Start: 2673320

End: 2674504

Strand: Reverse

Name: dapL [H]

Synonym: BVU_2062

Alternate gene names: 150004605

Gene position: 2674504-2673320 (Counterclockwise)

Preceding gene: 150004606

Following gene: 150004604

Centisome position: 51.8

GC content: 47.0

Gene sequence:

>1185_bases
ATGCAGAAGGAACATCAACCATATAATATTCAGCCGGCAGACCGTCTGGCGAATGTTAGCGAATACTACTTCAGCCGTAA
ACTGAAAGAAGTGGCACAAATGAATGCCGAAGGTAAAAATGTAATCAGTTTGGGTATCGGAAGCCCTGACATGCCTCCTT
CGGAAGAAACCGTCAATGTGTTGTGCGAACAGGCAAAGCGTCCTGATGCGCACGGATACCAACCTACTGTCGGCATTCTT
GAATTGCGCAAAGCCATGGCCGACTGGTACAAGCGTTGGTATCATGTAGAGCTTGATCCGGCAACCGAAATCCAGCCGCT
CATCGGTTCCAAAGAAGGTATCCTGCATGTGACGCTGGCATTGGTCAATCCGGGTGATCAGGTATTGGTTCCCAATCCGG
GGTATCCTACCTACACCTCTTTAAATAAAATATTGGGCAGTGAGATTGTGAACTACAACCTGCGCGAAGACAATCATTGG
CAACCCGATTTTGATGAACTGGAGAAGATGGACTTGAGCCGCGTCAAGATTATGTGGACCAACTATCCCAATATGCCGAC
CGGAGCGAACGCCACGATGGAACTGTATGAAAAGCTGGTAAACTTTGCACGCCGCCATAATATTGTGATTGTAAACGACA
ACCCATACAGCTTTATCCTGAACAAGAAACCACTGAGTATTCTTAATGTGCCCGGAGCCAAAGAATGCTGCATCGAGTTC
AACTCTATGAGCAAGAGCCACAACATGCCCGGCTGGCGTGTGGGAATGCTCGCCACCAATGCGCAGTTTGTACAATGGAT
ATTGAAAATAAAGAGTAATATTGACTCAGGAACTTTCCGCCCCATGCAACTGGCCGCCGCACAAGCTTACAACAACAGTG
TGGAATGGCACGAAGAAGCGAACGTCAATGTATATAGCCGTCGCCGCCAACTGGCAGAAGAGATTATGAAAGTACTCGGT
TGTAGCTTTGATCCCAATCAGGTAGGTATGTTCCTTTGGGGACGCATTCCCGAATCTTACAATGATGTAGAAGAACTGAC
CGAAAAAGTTTTGCACGAAGCACGTGTGTTCATTACTCCGGGCTTTATCTTCGGCAGCAACGGCAAACGCTATATCCGTA
TTTCCCTCTGTGCCAAAGAAGAAAAGCTGGCAGAAGCACTGGAAAGAATTAAAAAGATAATGTAA

Upstream 100 bases:

>100_bases
CTGTTCTATGTAGACGTAATTTTCAATGATTATTTAAGATACAAGCAGTCTATCGACGCCGTTTCACCATTGACAAAAGA
ACTTAAAATATTAGGAGAAT

Downstream 100 bases:

>100_bases
CAAAACAAAATATCAGATTATGGAATTAGATTTAAAACCCATCGAACTTCCGGGAATTGAAAAGAAACGCCCGATGATTA
TCGCCGGCCCATGTAGTGCC

Product: putative aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MQKEHQPYNIQPADRLANVSEYYFSRKLKEVAQMNAEGKNVISLGIGSPDMPPSEETVNVLCEQAKRPDAHGYQPTVGIL
ELRKAMADWYKRWYHVELDPATEIQPLIGSKEGILHVTLALVNPGDQVLVPNPGYPTYTSLNKILGSEIVNYNLREDNHW
QPDFDELEKMDLSRVKIMWTNYPNMPTGANATMELYEKLVNFARRHNIVIVNDNPYSFILNKKPLSILNVPGAKECCIEF
NSMSKSHNMPGWRVGMLATNAQFVQWILKIKSNIDSGTFRPMQLAAAQAYNNSVEWHEEANVNVYSRRRQLAEEIMKVLG
CSFDPNQVGMFLWGRIPESYNDVEELTEKVLHEARVFITPGFIFGSNGKRYIRISLCAKEEKLAEALERIKKIM

Sequences:

>Translated_394_residues
MQKEHQPYNIQPADRLANVSEYYFSRKLKEVAQMNAEGKNVISLGIGSPDMPPSEETVNVLCEQAKRPDAHGYQPTVGIL
ELRKAMADWYKRWYHVELDPATEIQPLIGSKEGILHVTLALVNPGDQVLVPNPGYPTYTSLNKILGSEIVNYNLREDNHW
QPDFDELEKMDLSRVKIMWTNYPNMPTGANATMELYEKLVNFARRHNIVIVNDNPYSFILNKKPLSILNVPGAKECCIEF
NSMSKSHNMPGWRVGMLATNAQFVQWILKIKSNIDSGTFRPMQLAAAQAYNNSVEWHEEANVNVYSRRRQLAEEIMKVLG
CSFDPNQVGMFLWGRIPESYNDVEELTEKVLHEARVFITPGFIFGSNGKRYIRISLCAKEEKLAEALERIKKIM
>Mature_394_residues
MQKEHQPYNIQPADRLANVSEYYFSRKLKEVAQMNAEGKNVISLGIGSPDMPPSEETVNVLCEQAKRPDAHGYQPTVGIL
ELRKAMADWYKRWYHVELDPATEIQPLIGSKEGILHVTLALVNPGDQVLVPNPGYPTYTSLNKILGSEIVNYNLREDNHW
QPDFDELEKMDLSRVKIMWTNYPNMPTGANATMELYEKLVNFARRHNIVIVNDNPYSFILNKKPLSILNVPGAKECCIEF
NSMSKSHNMPGWRVGMLATNAQFVQWILKIKSNIDSGTFRPMQLAAAQAYNNSVEWHEEANVNVYSRRRQLAEEIMKVLG
CSFDPNQVGMFLWGRIPESYNDVEELTEKVLHEARVFITPGFIFGSNGKRYIRISLCAKEEKLAEALERIKKIM

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=383, Percent_Identity=23.4986945169713, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI95147551, Length=234, Percent_Identity=27.3504273504274, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI169881279, Length=234, Percent_Identity=27.3504273504274, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI56713254, Length=266, Percent_Identity=24.812030075188, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI56713256, Length=266, Percent_Identity=24.812030075188, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI7705897, Length=408, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI33469970, Length=408, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=34.1085271317829, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1788627, Length=400, Percent_Identity=25.5, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786816, Length=367, Percent_Identity=24.5231607629428, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=297, Percent_Identity=28.2828282828283, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71994476, Length=291, Percent_Identity=28.5223367697594, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17567369, Length=402, Percent_Identity=23.3830845771144, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=25.4054054054054, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=24.9357326478149, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=24.9329758713137, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28573069, Length=261, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646114, Length=261, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573067, Length=261, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573065, Length=261, Percent_Identity=24.1379310344828, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 45066; Mature: 45066

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEHQPYNIQPADRLANVSEYYFSRKLKEVAQMNAEGKNVISLGIGSPDMPPSEETVNV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHH
LCEQAKRPDAHGYQPTVGILELRKAMADWYKRWYHVELDPATEIQPLIGSKEGILHVTLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHCCCCCCEEEEEEE
LVNPGDQVLVPNPGYPTYTSLNKILGSEIVNYNLREDNHWQPDFDELEKMDLSRVKIMWT
EECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEEE
NYPNMPTGANATMELYEKLVNFARRHNIVIVNDNPYSFILNKKPLSILNVPGAKECCIEF
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEECCCCHHHHHHH
NSMSKSHNMPGWRVGMLATNAQFVQWILKIKSNIDSGTFRPMQLAAAQAYNNSVEWHEEA
HHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
NVNVYSRRRQLAEEIMKVLGCSFDPNQVGMFLWGRIPESYNDVEELTEKVLHEARVFITP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEEEC
GFIFGSNGKRYIRISLCAKEEKLAEALERIKKIM
CEEECCCCCEEEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQKEHQPYNIQPADRLANVSEYYFSRKLKEVAQMNAEGKNVISLGIGSPDMPPSEETVNV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHH
LCEQAKRPDAHGYQPTVGILELRKAMADWYKRWYHVELDPATEIQPLIGSKEGILHVTLA
HHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHCCCCCCEEEEEEE
LVNPGDQVLVPNPGYPTYTSLNKILGSEIVNYNLREDNHWQPDFDELEKMDLSRVKIMWT
EECCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCEEEEEEE
NYPNMPTGANATMELYEKLVNFARRHNIVIVNDNPYSFILNKKPLSILNVPGAKECCIEF
CCCCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEECCCCHHHHHHH
NSMSKSHNMPGWRVGMLATNAQFVQWILKIKSNIDSGTFRPMQLAAAQAYNNSVEWHEEA
HHCCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCCC
NVNVYSRRRQLAEEIMKVLGCSFDPNQVGMFLWGRIPESYNDVEELTEKVLHEARVFITP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCEEEEEC
GFIFGSNGKRYIRISLCAKEEKLAEALERIKKIM
CEEECCCCCEEEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA