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The map label for this gene is recQ [H]

Identifier: 150004558

GI number: 150004558

Start: 2604180

End: 2605997

Strand: Reverse

Name: recQ [H]

Synonym: BVU_2013

Alternate gene names: 150004558

Gene position: 2605997-2604180 (Counterclockwise)

Preceding gene: 150004583

Following gene: 150004557

Centisome position: 50.47

GC content: 39.44

Gene sequence:

>1818_bases
ATGTTCCAAACTCTAAAAAACTACTTTGGATACGATAGTTTCCGTCCTTTACAGCAAGATATTATTCAAAATATATTAGC
TCAAAAGGATACTTTGGTATTAATGCCTACAGGAGGAGGAAAATCCATCTGTTATCAATTACCGGCTTTACTGATGGAAG
GTACGGCCATTGTCGTTTCACCCCTTATTTCTTTAATGAAAGACCAGGTGGAAAGTTTACAAGCAAACGGAATTGCAGCA
CGGGCACTGAACAGCAGCAATAATGAAACAGAAAATATAAACCTACGTCGCGAATGTCTTCAAGGAAAAATCAAATTACT
TTATATTTCACCTGAACGATTACTTATAGAAACAAATTTCCTGCTGAAAGATATCCAAATTTCTTTATTTGCCATTGATG
AAGCTCATTGCATCTCACAATGGGGACATGATTTCCGGCCTGAATATACCCAATTAAAGGTATTACGTAATCAGTTTCCC
AAAGTACCGATTGTAGCATTGACTGCTACAGCTGACAAAATAACCCGAAAAGACATTGTACAACAATTGGCCTTGAAAGA
TCCTAAAATATTCATATCTTCCTTTGATCGTCCCAATCTGAGTTTGGAAGTTAAAAGAGGCTATCAACAAAAGGATAAGA
TGCGGACTATTCTTGAATTCATAGAAAAACACAAAAATGAATGTGGTATCATTTATTGCATGAGCCGCAGCAAAACAGAA
AATGTGGCCGCAATGCTGATGAAACAAGGTATCCGTGCAACCGTTTATCATGCAGGATTAAGCAGCGATATGCGTGATAA
GGCACAAAATGATTTCATAAATGATCGTGTACAGGTGGTGTGCGCCACTATTGCTTTCGGGATGGGAATTGATAAATCCA
ATGTACGCTGGGTTATTCATTATAACCTTCCTAAAAGCATAGAAAGTTTCTATCAAGAAATAGGACGTGCCGGGCGTGAT
GGTATGGAAAGTGATACTTTGCTGTTCTATTCACTGGGAGACTTGGTTATGCTTTCCAAATTCGCTACAGAAAGCAGCCA
GCAGGAAATTAACTTAGAGAAATTACACCGGATGCAACAATATGCTGAATCGGATATCTGTCGGAGGCGTATCCTGCTGA
ACTATTTTGGTGAAACTATGGACCATGATTGTGGCAACTGTGATGTGTGCCGTAATCCCCCCGAACGCTTTGACGGAACA
ATCATTGTACAAAAAGCTTTGAGTGCAATAGCCCGAACTAACCAACAAATAGGTACTCACATGTTAATAGACATATTGAA
AGGGTCAGCAAACCAAGAACTGATTGACAAAGGTTATGACAAACTGAAAACATATGCCGCAGGAAGAGATATTCCCGCAC
GCGACTGGCAAGATTATCTGCTGCAAATGCTGAATCTAGGATATTTCGAAATAGCCTATAACGAGAACAATCACCTCAAA
ATAACTGAAAGCGGGCAAAAAGTATTGTTCGGCAAAGAATCCGCCATGCTGGTAGTCATTAAACGGGAAGAATTCGTACC
TGCTAAGGAAAAACGCAAAAAGAAAGCCAAGGAAGAGGTACTCTTTCCCACTCCGGTTACTTTTGGTAATGAAAACAAGG
ACTTGTTCGAGGAGTTACGTATACTGCGTAAAAAGCTGGCGGACCAGCAAGCTATACCTGCCTATATTGTTTTATCCGAC
AAGACTTTACACCTGATCGCCACCCAACAACCTACAACAATAGAAGCATTCGGCAACATCAATGGTATTGGCGAATATAA
GAAAGAAAAATACGGAAAAGAGTTTATAGAGTTGATAAAAAAGGTACTGAAGAAATGA

Upstream 100 bases:

>100_bases
AAAAGTATATCTTATTTACTATTATTAGGCAGAGATCCCTACCAAATCTAAAGATTTTACTACCTTTGTAACCGATTACA
TTTTAAAATAACAAACAGAT

Downstream 100 bases:

>100_bases
AAAACTATTCTTCCCATATACCAACAACAGGAACAGACAAATTCGGGACATTCATTAAATATTACAAAATCAGCCAACTA
ATTCATACACAAAGTATTGC

Product: putative ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MFQTLKNYFGYDSFRPLQQDIIQNILAQKDTLVLMPTGGGKSICYQLPALLMEGTAIVVSPLISLMKDQVESLQANGIAA
RALNSSNNETENINLRRECLQGKIKLLYISPERLLIETNFLLKDIQISLFAIDEAHCISQWGHDFRPEYTQLKVLRNQFP
KVPIVALTATADKITRKDIVQQLALKDPKIFISSFDRPNLSLEVKRGYQQKDKMRTILEFIEKHKNECGIIYCMSRSKTE
NVAAMLMKQGIRATVYHAGLSSDMRDKAQNDFINDRVQVVCATIAFGMGIDKSNVRWVIHYNLPKSIESFYQEIGRAGRD
GMESDTLLFYSLGDLVMLSKFATESSQQEINLEKLHRMQQYAESDICRRRILLNYFGETMDHDCGNCDVCRNPPERFDGT
IIVQKALSAIARTNQQIGTHMLIDILKGSANQELIDKGYDKLKTYAAGRDIPARDWQDYLLQMLNLGYFEIAYNENNHLK
ITESGQKVLFGKESAMLVVIKREEFVPAKEKRKKKAKEEVLFPTPVTFGNENKDLFEELRILRKKLADQQAIPAYIVLSD
KTLHLIATQQPTTIEAFGNINGIGEYKKEKYGKEFIELIKKVLKK

Sequences:

>Translated_605_residues
MFQTLKNYFGYDSFRPLQQDIIQNILAQKDTLVLMPTGGGKSICYQLPALLMEGTAIVVSPLISLMKDQVESLQANGIAA
RALNSSNNETENINLRRECLQGKIKLLYISPERLLIETNFLLKDIQISLFAIDEAHCISQWGHDFRPEYTQLKVLRNQFP
KVPIVALTATADKITRKDIVQQLALKDPKIFISSFDRPNLSLEVKRGYQQKDKMRTILEFIEKHKNECGIIYCMSRSKTE
NVAAMLMKQGIRATVYHAGLSSDMRDKAQNDFINDRVQVVCATIAFGMGIDKSNVRWVIHYNLPKSIESFYQEIGRAGRD
GMESDTLLFYSLGDLVMLSKFATESSQQEINLEKLHRMQQYAESDICRRRILLNYFGETMDHDCGNCDVCRNPPERFDGT
IIVQKALSAIARTNQQIGTHMLIDILKGSANQELIDKGYDKLKTYAAGRDIPARDWQDYLLQMLNLGYFEIAYNENNHLK
ITESGQKVLFGKESAMLVVIKREEFVPAKEKRKKKAKEEVLFPTPVTFGNENKDLFEELRILRKKLADQQAIPAYIVLSD
KTLHLIATQQPTTIEAFGNINGIGEYKKEKYGKEFIELIKKVLKK
>Mature_605_residues
MFQTLKNYFGYDSFRPLQQDIIQNILAQKDTLVLMPTGGGKSICYQLPALLMEGTAIVVSPLISLMKDQVESLQANGIAA
RALNSSNNETENINLRRECLQGKIKLLYISPERLLIETNFLLKDIQISLFAIDEAHCISQWGHDFRPEYTQLKVLRNQFP
KVPIVALTATADKITRKDIVQQLALKDPKIFISSFDRPNLSLEVKRGYQQKDKMRTILEFIEKHKNECGIIYCMSRSKTE
NVAAMLMKQGIRATVYHAGLSSDMRDKAQNDFINDRVQVVCATIAFGMGIDKSNVRWVIHYNLPKSIESFYQEIGRAGRD
GMESDTLLFYSLGDLVMLSKFATESSQQEINLEKLHRMQQYAESDICRRRILLNYFGETMDHDCGNCDVCRNPPERFDGT
IIVQKALSAIARTNQQIGTHMLIDILKGSANQELIDKGYDKLKTYAAGRDIPARDWQDYLLQMLNLGYFEIAYNENNHLK
ITESGQKVLFGKESAMLVVIKREEFVPAKEKRKKKAKEEVLFPTPVTFGNENKDLFEELRILRKKLADQQAIPAYIVLSD
KTLHLIATQQPTTIEAFGNINGIGEYKKEKYGKEFIELIKKVLKK

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI169218196, Length=681, Percent_Identity=33.1864904552129, Blast_Score=335, Evalue=7e-92,
Organism=Homo sapiens, GI110735439, Length=676, Percent_Identity=33.1360946745562, Blast_Score=335, Evalue=7e-92,
Organism=Homo sapiens, GI4557365, Length=656, Percent_Identity=35.5182926829268, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI14591902, Length=399, Percent_Identity=39.0977443609023, Blast_Score=302, Evalue=7e-82,
Organism=Homo sapiens, GI14591904, Length=399, Percent_Identity=39.0977443609023, Blast_Score=302, Evalue=7e-82,
Organism=Homo sapiens, GI148612816, Length=477, Percent_Identity=37.5262054507338, Blast_Score=291, Evalue=2e-78,
Organism=Homo sapiens, GI51242947, Length=351, Percent_Identity=43.3048433048433, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI51242943, Length=351, Percent_Identity=43.8746438746439, Blast_Score=276, Evalue=6e-74,
Organism=Homo sapiens, GI284005309, Length=352, Percent_Identity=37.5, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI262118318, Length=363, Percent_Identity=26.7217630853994, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI216548263, Length=363, Percent_Identity=26.7217630853994, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI262231852, Length=363, Percent_Identity=26.7217630853994, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI13518015, Length=363, Percent_Identity=26.7217630853994, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI38569503, Length=365, Percent_Identity=21.0958904109589, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI38569505, Length=364, Percent_Identity=21.1538461538462, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI41327771, Length=395, Percent_Identity=23.2911392405063, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI222352149, Length=356, Percent_Identity=23.876404494382, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994977, Length=603, Percent_Identity=46.1028192371476, Blast_Score=566, Evalue=1e-162,
Organism=Escherichia coli, GI87082221, Length=337, Percent_Identity=23.7388724035608, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787016, Length=349, Percent_Identity=24.9283667621776, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787605, Length=337, Percent_Identity=23.7388724035608, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=664, Percent_Identity=34.4879518072289, Blast_Score=350, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=33.6309523809524, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI71987993, Length=466, Percent_Identity=39.2703862660944, Blast_Score=309, Evalue=3e-84,
Organism=Caenorhabditis elegans, GI71987997, Length=466, Percent_Identity=39.2703862660944, Blast_Score=308, Evalue=4e-84,
Organism=Caenorhabditis elegans, GI17552866, Length=433, Percent_Identity=38.1062355658199, Blast_Score=268, Evalue=9e-72,
Organism=Caenorhabditis elegans, GI32565321, Length=383, Percent_Identity=24.0208877284595, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537549, Length=373, Percent_Identity=21.4477211796247, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17510307, Length=346, Percent_Identity=24.8554913294798, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17510309, Length=346, Percent_Identity=24.8554913294798, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71995514, Length=346, Percent_Identity=24.8554913294798, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17555296, Length=334, Percent_Identity=23.9520958083832, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=521, Percent_Identity=36.2763915547025, Blast_Score=329, Evalue=8e-91,
Organism=Saccharomyces cerevisiae, GI6320224, Length=358, Percent_Identity=23.1843575418994, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324217, Length=351, Percent_Identity=21.9373219373219, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320041, Length=331, Percent_Identity=22.6586102719033, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321360, Length=335, Percent_Identity=23.8805970149254, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323947, Length=358, Percent_Identity=23.7430167597765, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24646066, Length=637, Percent_Identity=34.5368916797488, Blast_Score=346, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24664226, Length=431, Percent_Identity=34.5707656612529, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24664230, Length=431, Percent_Identity=34.338747099768, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI62472181, Length=431, Percent_Identity=34.5707656612529, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI21358123, Length=352, Percent_Identity=36.3636363636364, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI21355075, Length=375, Percent_Identity=22.9333333333333, Blast_Score=80, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24584994, Length=394, Percent_Identity=24.1116751269036, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24583281, Length=326, Percent_Identity=22.3926380368098, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24583279, Length=326, Percent_Identity=22.3926380368098, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666101, Length=348, Percent_Identity=22.1264367816092, Blast_Score=67, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 69127; Mature: 69127

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTLKNYFGYDSFRPLQQDIIQNILAQKDTLVLMPTGGGKSICYQLPALLMEGTAIVVS
CCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHH
PLISLMKDQVESLQANGIAARALNSSNNETENINLRRECLQGKIKLLYISPERLLIETNF
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCEEEEECCH
LLKDIQISLFAIDEAHCISQWGHDFRPEYTQLKVLRNQFPKVPIVALTATADKITRKDIV
HHEEEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
QQLALKDPKIFISSFDRPNLSLEVKRGYQQKDKMRTILEFIEKHKNECGIIYCMSRSKTE
HHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
NVAAMLMKQGIRATVYHAGLSSDMRDKAQNDFINDRVQVVCATIAFGMGIDKSNVRWVIH
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
YNLPKSIESFYQEIGRAGRDGMESDTLLFYSLGDLVMLSKFATESSQQEINLEKLHRMQQ
ECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
YAESDICRRRILLNYFGETMDHDCGNCDVCRNPPERFDGTIIVQKALSAIARTNQQIGTH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHH
MLIDILKGSANQELIDKGYDKLKTYAAGRDIPARDWQDYLLQMLNLGYFEIAYNENNHLK
HHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEE
ITESGQKVLFGKESAMLVVIKREEFVPAKEKRKKKAKEEVLFPTPVTFGNENKDLFEELR
EECCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ILRKKLADQQAIPAYIVLSDKTLHLIATQQPTTIEAFGNINGIGEYKKEKYGKEFIELIK
HHHHHHCCCCCCCEEEEEECCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
KVLKK
HHHCC
>Mature Secondary Structure
MFQTLKNYFGYDSFRPLQQDIIQNILAQKDTLVLMPTGGGKSICYQLPALLMEGTAIVVS
CCHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHH
PLISLMKDQVESLQANGIAARALNSSNNETENINLRRECLQGKIKLLYISPERLLIETNF
HHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHCCCEEEEEECCCEEEEECCH
LLKDIQISLFAIDEAHCISQWGHDFRPEYTQLKVLRNQFPKVPIVALTATADKITRKDIV
HHEEEEEEEEEECHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
QQLALKDPKIFISSFDRPNLSLEVKRGYQQKDKMRTILEFIEKHKNECGIIYCMSRSKTE
HHHHCCCCCEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCH
NVAAMLMKQGIRATVYHAGLSSDMRDKAQNDFINDRVQVVCATIAFGMGIDKSNVRWVIH
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
YNLPKSIESFYQEIGRAGRDGMESDTLLFYSLGDLVMLSKFATESSQQEINLEKLHRMQQ
ECCCHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCHHCCCHHHHHHHHH
YAESDICRRRILLNYFGETMDHDCGNCDVCRNPPERFDGTIIVQKALSAIARTNQQIGTH
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHCCEEHHHHHHHHHHHHHHHHHHH
MLIDILKGSANQELIDKGYDKLKTYAAGRDIPARDWQDYLLQMLNLGYFEIAYNENNHLK
HHHHHHHCCCCHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCEEE
ITESGQKVLFGKESAMLVVIKREEFVPAKEKRKKKAKEEVLFPTPVTFGNENKDLFEELR
EECCCCEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
ILRKKLADQQAIPAYIVLSDKTLHLIATQQPTTIEAFGNINGIGEYKKEKYGKEFIELIK
HHHHHHCCCCCCCEEEEEECCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
KVLKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]