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The map label for this gene is fabI2 [H]

Identifier: 150004536

GI number: 150004536

Start: 2572035

End: 2572892

Strand: Direct

Name: fabI2 [H]

Synonym: BVU_1986

Alternate gene names: 150004536

Gene position: 2572035-2572892 (Clockwise)

Preceding gene: 150004526

Following gene: 150004537

Centisome position: 49.81

GC content: 40.44

Gene sequence:

>858_bases
ATGAGTTACAATTTGTTGAAAGGAAAAAGAGGTATTATTTTTGGTGCATTGAACGAACAGTCTATCGCATGGAAAGTTGC
TGAAAAGGCTGTAGAAGAAGGTGCGTCCATTACATTGTCCAATACTCCGGTAGCTGTCCGTATGGGAGAAGTTTCTGCTT
TAGCTGAGAAACTGAATTGTGAGGTAATTCCGGCAGATGCAACCAGCGTAGAAGATTTGGAGAATGTTTTCAAACGTTCG
ATGGAAATATTAGGTGGAAAAATAGATTTCGTTCTGCATTCTATCGGTATGTCTCCTAACGTTCGTAAGAAACGTACTTA
TGATGACCTCGATTATGATATGTTGAGCAAGACTCTGGATATATCTGCCGTTTCGTTCCACAAAATGATTCAAGCTGCTA
AAAAGCTGGATGCTATTGCGGAGTATGGTTCAATTTTGGCTTTGAGTTATGTTGCTGCACAACGTACATTCTATGGATAT
AATGATATGGCGGATGCAAAAGCATTGCTTGAATCTATCGCACGCAGTTTTGGTTACATTTATGGTCGTGAACATCATGT
GCGTGTGAATACCATATCTCAGTCACCGACCATGACTACTGCCGGTTCAGGTGTGAAAGGTATGGATAAGCTGTTTGACT
TTGCTAACCGTATGTCACCATTAGGCAATGCTTCGGCAGACGAATGTGCAGATTACTGCATTGTAATGTTCTCTGACCTG
ACTCGTAAAGTGACTATGCAGAATTTATATCATGATGGAGGTTTCTCCAGTGTAGGTATGAGTTTGCGTGCTATGGCAAC
TTATGAAAAAGGTCTGGATGAATATAAAGACGAAAACGGAAACATCATTTACGGATAA

Upstream 100 bases:

>100_bases
TAGTTTTATAATTGCATTATTTCTTCATTTGTGTGCAAAAAAAGCTATGATTAATTTATTTGTTTGTATCTTTGCAAACT
AATTTAACAATAAAGAAGGT

Downstream 100 bases:

>100_bases
GAAATAGATGATGCGCAAAATTATATTCATATTAGTAGTATGTCTTGTTGCTCTTTCCTCCTGTCAGTGGGATGGGAAGA
GTGGCAATACTGCTGATGTG

Product: enoyl-[acyl-carrier-protein] reductase

Products: NA

Alternate protein names: NADH-dependent enoyl-ACP reductase 2 [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSYNLLKGKRGIIFGALNEQSIAWKVAEKAVEEGASITLSNTPVAVRMGEVSALAEKLNCEVIPADATSVEDLENVFKRS
MEILGGKIDFVLHSIGMSPNVRKKRTYDDLDYDMLSKTLDISAVSFHKMIQAAKKLDAIAEYGSILALSYVAAQRTFYGY
NDMADAKALLESIARSFGYIYGREHHVRVNTISQSPTMTTAGSGVKGMDKLFDFANRMSPLGNASADECADYCIVMFSDL
TRKVTMQNLYHDGGFSSVGMSLRAMATYEKGLDEYKDENGNIIYG

Sequences:

>Translated_285_residues
MSYNLLKGKRGIIFGALNEQSIAWKVAEKAVEEGASITLSNTPVAVRMGEVSALAEKLNCEVIPADATSVEDLENVFKRS
MEILGGKIDFVLHSIGMSPNVRKKRTYDDLDYDMLSKTLDISAVSFHKMIQAAKKLDAIAEYGSILALSYVAAQRTFYGY
NDMADAKALLESIARSFGYIYGREHHVRVNTISQSPTMTTAGSGVKGMDKLFDFANRMSPLGNASADECADYCIVMFSDL
TRKVTMQNLYHDGGFSSVGMSLRAMATYEKGLDEYKDENGNIIYG
>Mature_284_residues
SYNLLKGKRGIIFGALNEQSIAWKVAEKAVEEGASITLSNTPVAVRMGEVSALAEKLNCEVIPADATSVEDLENVFKRSM
EILGGKIDFVLHSIGMSPNVRKKRTYDDLDYDMLSKTLDISAVSFHKMIQAAKKLDAIAEYGSILALSYVAAQRTFYGYN
DMADAKALLESIARSFGYIYGREHHVRVNTISQSPTMTTAGSGVKGMDKLFDFANRMSPLGNASADECADYCIVMFSDLT
RKVTMQNLYHDGGFSSVGMSLRAMATYEKGLDEYKDENGNIIYG

Specific function: Fatty acid biosynthesis pathway; second reduction step. [C]

COG id: COG0623

COG function: function code I; Enoyl-[acyl-carrier-protein] reductase (NADH)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787545, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR014358
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.9 [H]

Molecular weight: Translated: 31325; Mature: 31194

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYNLLKGKRGIIFGALNEQSIAWKVAEKAVEEGASITLSNTPVAVRMGEVSALAEKLNC
CCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECHHHHHHHHHCC
EVIPADATSVEDLENVFKRSMEILGGKIDFVLHSIGMSPNVRKKRTYDDLDYDMLSKTLD
EEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHC
ISAVSFHKMIQAAKKLDAIAEYGSILALSYVAAQRTFYGYNDMADAKALLESIARSFGYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YGREHHVRVNTISQSPTMTTAGSGVKGMDKLFDFANRMSPLGNASADECADYCIVMFSDL
CCCCEEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TRKVTMQNLYHDGGFSSVGMSLRAMATYEKGLDEYKDENGNIIYG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
>Mature Secondary Structure 
SYNLLKGKRGIIFGALNEQSIAWKVAEKAVEEGASITLSNTPVAVRMGEVSALAEKLNC
CCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEECCCCEEEEECHHHHHHHHHCC
EVIPADATSVEDLENVFKRSMEILGGKIDFVLHSIGMSPNVRKKRTYDDLDYDMLSKTLD
EEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHC
ISAVSFHKMIQAAKKLDAIAEYGSILALSYVAAQRTFYGYNDMADAKALLESIARSFGYI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
YGREHHVRVNTISQSPTMTTAGSGVKGMDKLFDFANRMSPLGNASADECADYCIVMFSDL
CCCCEEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
TRKVTMQNLYHDGGFSSVGMSLRAMATYEKGLDEYKDENGNIIYG
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]