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The map label for this gene is namA [H]

Identifier: 150004515

GI number: 150004515

Start: 2545898

End: 2547121

Strand: Direct

Name: namA [H]

Synonym: BVU_1965

Alternate gene names: 150004515

Gene position: 2545898-2547121 (Clockwise)

Preceding gene: 150004514

Following gene: 150004516

Centisome position: 49.31

GC content: 46.57

Gene sequence:

>1224_bases
ATGAACTCTAAATTATTTACTCCCGCTTCTATCGGACCGCTGACTTTGCGTAACCGTACGATTCGTTCGGCTGCTTTTGA
GAGTATGTGTCCGGGCAATGCTCCGTCCCGGCAATTGAAGGATTATCACTGCTCGGTGGCGGCAGGTGGAGTGGGAATGA
CTACTATTGCTTATGCAGCAGTTACACAGAGTGGCCTTTCTTTCGACAGGCAATTGTGGATGCGCCCTGAAATTATACCG
GGATTAAGGGAAATAACCGATGCGGTTCATAAAGAAGGGGCTGCCGTAAGCATTCAGTTGGGACATTGTGGAAATATGTC
GCACAAAAGTATTTGTGGGGTAACACCCATAGGAGCTTCTTCCGGTTTTAATCTTTATTCGCCTACTTTCGTGCGTGGCT
TGCGCAAGGAGGAACTGCCGCAGATGGCAAAGGCATACGGTCAGTCGGTCAACTGGGCGCGTGAGGCCGGATTTGACGCG
GTGGAGATACATGCGGGGCATGGCTATCTTATCAGTCAGTTTCTTTCACCTTACACCAATCATCGTAAAGACGAGTTCGG
CGGCTCGTTGGAGAATCGTATGCGCTTTATGGATATGGTGATGGAGGAAGTGATGCGTGCCGCAGGTAATGACATGGCCG
TTCTGGTAAAAACCAATATGCGTGACGGTTTTAAAGGAGGAATGGAAATAGATGAAGCTGTGCAGGTAGCGAAACGGTTG
GTACAGGACGGGGCTCATGCGTTGGTGCTGAGTGGAGGTTTTGTAAGCAAAGCGCCTATGTATGTCATGCGGGGAGCGAT
GCCTATAAAAAGTATGACACATTATATGAACTGTTGGTGGCTGAAATATGGGGTGCGTATGGTAGGCAAATGGATGATTC
CGACAGTACCTTTCAAAGAGGCTTATTTTTTGGAAGATGCATTGAGATTCAGAACAGAAATAAAGGAAATTCCGTTAGTA
TATGTGGGGGGGCTGGTATCTCGTGAAAAGATAGATGAGGTATTGGATGATGGTTTTGAATTTGTACAGATGGGAAGGGC
GTTGCTGAATGAACCTGGTTTTGTGAATCGGTTGCGCACTGAAGAAAAGGCGCGTTGCAATTGCGGTCATAGTAATTATT
GCATTGCGAGAATGTACACTATTGATATGGCATGCCACAAACATTTGGAAGAGAAATTGCCCCTTTGCTTGGAACGTGAA
ATAGAAAAATTAGAGAACCAATGA

Upstream 100 bases:

>100_bases
TAGGAAAAAAGAAAAGAATGATTCCTTTTATTTATTGAATTTGAATAGTATATCGTTTCTGTTTCAGGAAATGATGAAAG
CGAAACATAACATATGAATG

Downstream 100 bases:

>100_bases
GTAAATTAGCCATAATAACCGGTGCCGATGGAGGAATGGGAACCGAAATAACCCGTGCGGTAGCACAGGCCGGTTATCAT
GTAATTATGTTGTGCTACAC

Product: putative NADH:flavin oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MNSKLFTPASIGPLTLRNRTIRSAAFESMCPGNAPSRQLKDYHCSVAAGGVGMTTIAYAAVTQSGLSFDRQLWMRPEIIP
GLREITDAVHKEGAAVSIQLGHCGNMSHKSICGVTPIGASSGFNLYSPTFVRGLRKEELPQMAKAYGQSVNWAREAGFDA
VEIHAGHGYLISQFLSPYTNHRKDEFGGSLENRMRFMDMVMEEVMRAAGNDMAVLVKTNMRDGFKGGMEIDEAVQVAKRL
VQDGAHALVLSGGFVSKAPMYVMRGAMPIKSMTHYMNCWWLKYGVRMVGKWMIPTVPFKEAYFLEDALRFRTEIKEIPLV
YVGGLVSREKIDEVLDDGFEFVQMGRALLNEPGFVNRLRTEEKARCNCGHSNYCIARMYTIDMACHKHLEEKLPLCLERE
IEKLENQ

Sequences:

>Translated_407_residues
MNSKLFTPASIGPLTLRNRTIRSAAFESMCPGNAPSRQLKDYHCSVAAGGVGMTTIAYAAVTQSGLSFDRQLWMRPEIIP
GLREITDAVHKEGAAVSIQLGHCGNMSHKSICGVTPIGASSGFNLYSPTFVRGLRKEELPQMAKAYGQSVNWAREAGFDA
VEIHAGHGYLISQFLSPYTNHRKDEFGGSLENRMRFMDMVMEEVMRAAGNDMAVLVKTNMRDGFKGGMEIDEAVQVAKRL
VQDGAHALVLSGGFVSKAPMYVMRGAMPIKSMTHYMNCWWLKYGVRMVGKWMIPTVPFKEAYFLEDALRFRTEIKEIPLV
YVGGLVSREKIDEVLDDGFEFVQMGRALLNEPGFVNRLRTEEKARCNCGHSNYCIARMYTIDMACHKHLEEKLPLCLERE
IEKLENQ
>Mature_407_residues
MNSKLFTPASIGPLTLRNRTIRSAAFESMCPGNAPSRQLKDYHCSVAAGGVGMTTIAYAAVTQSGLSFDRQLWMRPEIIP
GLREITDAVHKEGAAVSIQLGHCGNMSHKSICGVTPIGASSGFNLYSPTFVRGLRKEELPQMAKAYGQSVNWAREAGFDA
VEIHAGHGYLISQFLSPYTNHRKDEFGGSLENRMRFMDMVMEEVMRAAGNDMAVLVKTNMRDGFKGGMEIDEAVQVAKRL
VQDGAHALVLSGGFVSKAPMYVMRGAMPIKSMTHYMNCWWLKYGVRMVGKWMIPTVPFKEAYFLEDALRFRTEIKEIPLV
YVGGLVSREKIDEVLDDGFEFVQMGRALLNEPGFVNRLRTEEKARCNCGHSNYCIARMYTIDMACHKHLEEKLPLCLERE
IEKLENQ

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=228, Percent_Identity=32.0175438596491, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789463, Length=243, Percent_Identity=30.4526748971193, Blast_Score=115, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17559802, Length=223, Percent_Identity=27.8026905829596, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI72001454, Length=279, Percent_Identity=25.4480286738351, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565138, Length=287, Percent_Identity=25.4355400696864, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=280, Percent_Identity=26.0714285714286, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=279, Percent_Identity=24.3727598566308, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=279, Percent_Identity=24.3727598566308, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=260, Percent_Identity=26.9230769230769, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=225, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=225, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 45544; Mature: 45544

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKLFTPASIGPLTLRNRTIRSAAFESMCPGNAPSRQLKDYHCSVAAGGVGMTTIAYAA
CCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHCEEEECCCHHHHHHHHH
VTQSGLSFDRQLWMRPEIIPGLREITDAVHKEGAAVSIQLGHCGNMSHKSICGVTPIGAS
HHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
SGFNLYSPTFVRGLRKEELPQMAKAYGQSVNWAREAGFDAVEIHAGHGYLISQFLSPYTN
CCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHC
HRKDEFGGSLENRMRFMDMVMEEVMRAAGNDMAVLVKTNMRDGFKGGMEIDEAVQVAKRL
CCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
VQDGAHALVLSGGFVSKAPMYVMRGAMPIKSMTHYMNCWWLKYGVRMVGKWMIPTVPFKE
HHCCCCEEEEECCCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AYFLEDALRFRTEIKEIPLVYVGGLVSREKIDEVLDDGFEFVQMGRALLNEPGFVNRLRT
HHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
EEKARCNCGHSNYCIARMYTIDMACHKHLEEKLPLCLEREIEKLENQ
CHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNSKLFTPASIGPLTLRNRTIRSAAFESMCPGNAPSRQLKDYHCSVAAGGVGMTTIAYAA
CCCCCCCCCCCCCCHHCCHHHHHHHHHHCCCCCCCHHHHHHHHCEEEECCCHHHHHHHHH
VTQSGLSFDRQLWMRPEIIPGLREITDAVHKEGAAVSIQLGHCGNMSHKSICGVTPIGAS
HHHHCCCHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
SGFNLYSPTFVRGLRKEELPQMAKAYGQSVNWAREAGFDAVEIHAGHGYLISQFLSPYTN
CCCCCCCHHHHHHCCHHHHHHHHHHHCCCCCHHHHCCCCEEEEECCCCHHHHHHHHHHHC
HRKDEFGGSLENRMRFMDMVMEEVMRAAGNDMAVLVKTNMRDGFKGGMEIDEAVQVAKRL
CCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHH
VQDGAHALVLSGGFVSKAPMYVMRGAMPIKSMTHYMNCWWLKYGVRMVGKWMIPTVPFKE
HHCCCCEEEEECCCCHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AYFLEDALRFRTEIKEIPLVYVGGLVSREKIDEVLDDGFEFVQMGRALLNEPGFVNRLRT
HHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCC
EEKARCNCGHSNYCIARMYTIDMACHKHLEEKLPLCLEREIEKLENQ
CHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA