Click here to switch to the map view.

The map label for this gene is sigW [H]

Identifier: 150004502

GI number: 150004502

Start: 2529546

End: 2530094

Strand: Reverse

Name: sigW [H]

Synonym: BVU_1952

Alternate gene names: 150004502

Gene position: 2530094-2529546 (Counterclockwise)

Preceding gene: 150004503

Following gene: 150004501

Centisome position: 49.0

GC content: 39.71

Gene sequence:

>549_bases
ATGAGCCAAATCAACGACATAGCGTTGGTAGCACAAGTGGTGGTCTTTAAAAACACCCGGGCGTTTGATACTTTGGTCAA
AAAGTACCAATCGCCCATCAGGCGTTTTTTCCTGCACCAAACATTGGGAGATACAGAGCTCAGCGATGACTTGGCACAGG
AAACTTTTATAAAAGCATACACCAACTTGGCTTCATTTAAAAATTTGTCCAGTTTCTCCACATGGCTTTACCGTATTGCT
TATAATATATTTTATGACTATATTCGCAGCAAAAAAGAAACGTCCGGACTGGAAACTTGGGAAATAGACGCTGTTTACCA
AACAGAACAAAGGCAAGTAGGTGAACACATGGACATATATCGGGGATTGAGCCAATTAAAAGAGGTAGAGCGAACCTGCA
TCACCTTATTTTTTATGGAAGATCTTCCGATAGAAAAAATTGCAGTGATTACAGGAATGCCTGCAGGAACAATCAAGTCC
CATTTATCACGCGGAAAAACAAAATTGACAACTTTCTTAAAACAGAATGGTTATGATGGAAAACGATGA

Upstream 100 bases:

>100_bases
CAATGAAAATTGAAAATATTGAACTGGGACGTAACAAAGAGACCAAAGAAACACAAAACATAAAGAACAATATAGACACT
CCCTACAACGAAGAATAAAA

Downstream 100 bases:

>100_bases
TACATTAATTAAGAATTTCATGCTTGCCAACAAACATGAAATTGAGGACAATGGATTTTCACGCGGGGTTATCCGCCGCC
TCCCCCAACCAGCCCAATGG

Product: RNA polymerase ECF-type sigma factor

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSQINDIALVAQVVVFKNTRAFDTLVKKYQSPIRRFFLHQTLGDTELSDDLAQETFIKAYTNLASFKNLSSFSTWLYRIA
YNIFYDYIRSKKETSGLETWEIDAVYQTEQRQVGEHMDIYRGLSQLKEVERTCITLFFMEDLPIEKIAVITGMPAGTIKS
HLSRGKTKLTTFLKQNGYDGKR

Sequences:

>Translated_182_residues
MSQINDIALVAQVVVFKNTRAFDTLVKKYQSPIRRFFLHQTLGDTELSDDLAQETFIKAYTNLASFKNLSSFSTWLYRIA
YNIFYDYIRSKKETSGLETWEIDAVYQTEQRQVGEHMDIYRGLSQLKEVERTCITLFFMEDLPIEKIAVITGMPAGTIKS
HLSRGKTKLTTFLKQNGYDGKR
>Mature_181_residues
SQINDIALVAQVVVFKNTRAFDTLVKKYQSPIRRFFLHQTLGDTELSDDLAQETFIKAYTNLASFKNLSSFSTWLYRIAY
NIFYDYIRSKKETSGLETWEIDAVYQTEQRQVGEHMDIYRGLSQLKEVERTCITLFFMEDLPIEKIAVITGMPAGTIKSH
LSRGKTKLTTFLKQNGYDGKR

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=182, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21090; Mature: 20959

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQINDIALVAQVVVFKNTRAFDTLVKKYQSPIRRFFLHQTLGDTELSDDLAQETFIKAY
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TNLASFKNLSSFSTWLYRIAYNIFYDYIRSKKETSGLETWEIDAVYQTEQRQVGEHMDIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
RGLSQLKEVERTCITLFFMEDLPIEKIAVITGMPAGTIKSHLSRGKTKLTTFLKQNGYDG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCCCC
KR
CC
>Mature Secondary Structure 
SQINDIALVAQVVVFKNTRAFDTLVKKYQSPIRRFFLHQTLGDTELSDDLAQETFIKAY
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TNLASFKNLSSFSTWLYRIAYNIFYDYIRSKKETSGLETWEIDAVYQTEQRQVGEHMDIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHH
RGLSQLKEVERTCITLFFMEDLPIEKIAVITGMPAGTIKSHLSRGKTKLTTFLKQNGYDG
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHHHCCCCC
KR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]