Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 150004434

GI number: 150004434

Start: 2454734

End: 2455168

Strand: Direct

Name: tadA [H]

Synonym: BVU_1881

Alternate gene names: 150004434

Gene position: 2454734-2455168 (Clockwise)

Preceding gene: 150004433

Following gene: 150004438

Centisome position: 47.54

GC content: 46.9

Gene sequence:

>435_bases
ATGGCAGATGATACCTATTATATGAAACAAGCCTTGATGGAGGCTGTAAAAGCGGCTGAACAAGGAGAAGTTCCGGTGGG
GGCGGTGGTAGTCTGTCGTGACCGCATCATTGGTCGTGGGCATAATTTGACAGAAACATTGAATGATGTTACAGCTCATG
CCGAAATGCAGGCTGTCACAGCTGCGGCTAATACCTTGGGCGGGAAATACCTGAATGAATGTACTTTGTATGTCACTGTG
GAACCGTGTGTGATGTGTGCCGGTGCCATAGCCTGGGCACAGACAGGAAAACTTGTCTTTGGTGCTGAAGATCCCAAAAG
GGGATATCAAAAATATGCCCCCGATGCCTTGCATCCAAAGACGATCGTGGTGAAAGGAATACTCGCCGATGAATGTGCCC
GATTGATGAAAGATTTCTTTAAGAAAAAACGATAA

Upstream 100 bases:

>100_bases
AAGGCGCGTTGGTTACGCGAAACAGTATTGACTTTTATCCATCAGAAGATGGAAGAGGATTATCCTACATTGTTTAATGA
ACATGATATGAGAAGATAAG

Downstream 100 bases:

>100_bases
TTCTTATTTCACCTCTTCATAATCTACATACTCTCCCTCATCGTCATCAAAGATTTTTTTTCTGTTTCCCGATGAATGAG
AATGTCTATTTGAAGAAGAT

Product: putative cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 143

Protein sequence:

>144_residues
MADDTYYMKQALMEAVKAAEQGEVPVGAVVVCRDRIIGRGHNLTETLNDVTAHAEMQAVTAAANTLGGKYLNECTLYVTV
EPCVMCAGAIAWAQTGKLVFGAEDPKRGYQKYAPDALHPKTIVVKGILADECARLMKDFFKKKR

Sequences:

>Translated_144_residues
MADDTYYMKQALMEAVKAAEQGEVPVGAVVVCRDRIIGRGHNLTETLNDVTAHAEMQAVTAAANTLGGKYLNECTLYVTV
EPCVMCAGAIAWAQTGKLVFGAEDPKRGYQKYAPDALHPKTIVVKGILADECARLMKDFFKKKR
>Mature_143_residues
ADDTYYMKQALMEAVKAAEQGEVPVGAVVVCRDRIIGRGHNLTETLNDVTAHAEMQAVTAAANTLGGKYLNECTLYVTVE
PCVMCAGAIAWAQTGKLVFGAEDPKRGYQKYAPDALHPKTIVVKGILADECARLMKDFFKKKR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=30.4635761589404, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI145693172, Length=144, Percent_Identity=45.1388888888889, Blast_Score=124, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=35.8108108108108, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=39.1752577319588, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=37.7551020408163, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355527, Length=143, Percent_Identity=33.5664335664336, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 15696; Mature: 15565

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDTYYMKQALMEAVKAAEQGEVPVGAVVVCRDRIIGRGHNLTETLNDVTAHAEMQAVT
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAANTLGGKYLNECTLYVTVEPCVMCAGAIAWAQTGKLVFGAEDPKRGYQKYAPDALHPK
HHHHHHCCHHHHHEEEEEEECHHHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCC
TIVVKGILADECARLMKDFFKKKR
HHEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADDTYYMKQALMEAVKAAEQGEVPVGAVVVCRDRIIGRGHNLTETLNDVTAHAEMQAVT
CCCHHHHHHHHHHHHHHHHCCCCCCHHHEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAANTLGGKYLNECTLYVTVEPCVMCAGAIAWAQTGKLVFGAEDPKRGYQKYAPDALHPK
HHHHHHCCHHHHHEEEEEEECHHHHHHHHHHHHHCCCEEECCCCCHHHHHHCCCCCCCCC
TIVVKGILADECARLMKDFFKKKR
HHEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]