Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 150004380

GI number: 150004380

Start: 2371715

End: 2373169

Strand: Direct

Name: mrdB [H]

Synonym: BVU_1826

Alternate gene names: 150004380

Gene position: 2371715-2373169 (Clockwise)

Preceding gene: 150004379

Following gene: 150004386

Centisome position: 45.94

GC content: 41.58

Gene sequence:

>1455_bases
ATGGCATACACGAACGATAGTATATGGAAATCAGTGGACTGGATGACTATCTGCATTTATCTGATGCTGGTTATCTTTGG
ATGGTTCAGCGTATGTGGAGCCAGCTATGATTATGGTGAGATTGATTTTTTTAGTTTCGACACTAGGGCAGGAAAACAGT
TTGTATGGATCTGTTGCTCTTTGGGGCTCGGATTTATCCTGATGATGTTGGAGGATAAGTTGTATGATATGTTTGCTTAT
ATTTTATATGGAGGCATGATGCTGCTGTTGTTGATAACACCTTTTCTGGCAGAGGATACTAAGGGATCTTACTCATGGAT
AAAATTCGGACCTGTAAGTTTGCAACCGGCGGAATTTGCTAAATTTGCCACGGCGCTGGCTTTGGCTAAATTTATGAATG
TCTACGGGTTTACAATGAGTAAGTTAAAGTATTCATTGCCTGTGGTAGGGATGGTGTTGCTGCCCATGCTGCTTATTATT
TTGCAACGGGAAACGGGGTCGGCTTTGGTTTATCTGGCTTTCTTTTTTATGCTGTACCGGGAGGGGATGCCGGGTTCTAT
TTTGTTTGCCGGGATTTGCGCCGTGGTCTATTTTGTAGTTGGAATCCGTTTTGGCAATGAATTGATGGCGGATGACTGTA
CTTCCATCGGTGAATTTTCTGTGTTGCTGCTGATAGTCATCCTTTCTGCTTTATTAGTTAATAGTTATTGCAAAAAAGCA
TCGGTAGTGTGGTATATCGGAGGGATTGGTGTTGGTGGTACCTTGCTGGCTTTATTATTTTCGTATTATGTTATCCCTTT
TGACATTACTTGGTTCCAATATGGATTGTGCGTAGTTTTATTGTTCTATTTGATCTTCCTTTCTATGCATGAACGTATGC
GTAATTATTTTTATATTGCTCTATTTGCGATAGGTTCGGTGGGATTTCTTTTTTCTGCCGATTATGTTTTCAATAATGTG
CTGGAGCCACATCAGCAGATACGTATTAAAGTGGTGCTTGGTATGGAGGAAGATTTGGCGGGGGCAGGATACAATGTGAA
TCAGAGTAAGATTGCTATTGGGTCGGGAGGCTTATGGGGGAAAGGCTTTTTGAATGGTACACAGACTAAACTGAAGTATG
TGCCTGAACAGGATACAGACTTTATCTTCTGTACGGTAGGGGAAGAAGAAGGCTTTGTAGGTTCGGCGGCCGTATTGTTT
CTTTTTACCGGACTTATTTTGCGTCTTATTGTGGTGGCGGAGCGTCAGCATACTCGTTTTGCCCGTGTTTATGGATATTC
GGTATTAAGCATTTTCTTATTCCATCTGTTTATTAATATAGGTATGGTTTTAGGACTGACCCCCGTTATAGGCATACCAC
TGCCTTTTTTCAGTTATGGGGGATCTTCTTTGTGGGGATTTACGATCTTGCTTTTTGTATTCTTGCGTATTGATGCAGGG
CGGGGAAAACGTTAG

Upstream 100 bases:

>100_bases
GTACCTATCGGTGCATTGATAATGGAGAAATATTTAAAAGGCGAACTTTCACCGGAAAGTGAGGCGAAAGCGGCGGAAAT
ACAAAACAGACGAATAGATT

Downstream 100 bases:

>100_bases
AGCTTATTGGTTTTCCGGTTTGCGCAACCGGATACCTATATCGCTGATTCCCGTCAACGGGTTGTCCGTCATGATATGGA
CGATGCGGAAAGTACGTGCG

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAYTNDSIWKSVDWMTICIYLMLVIFGWFSVCGASYDYGEIDFFSFDTRAGKQFVWICCSLGLGFILMMLEDKLYDMFAY
ILYGGMMLLLLITPFLAEDTKGSYSWIKFGPVSLQPAEFAKFATALALAKFMNVYGFTMSKLKYSLPVVGMVLLPMLLII
LQRETGSALVYLAFFFMLYREGMPGSILFAGICAVVYFVVGIRFGNELMADDCTSIGEFSVLLLIVILSALLVNSYCKKA
SVVWYIGGIGVGGTLLALLFSYYVIPFDITWFQYGLCVVLLFYLIFLSMHERMRNYFYIALFAIGSVGFLFSADYVFNNV
LEPHQQIRIKVVLGMEEDLAGAGYNVNQSKIAIGSGGLWGKGFLNGTQTKLKYVPEQDTDFIFCTVGEEEGFVGSAAVLF
LFTGLILRLIVVAERQHTRFARVYGYSVLSIFLFHLFINIGMVLGLTPVIGIPLPFFSYGGSSLWGFTILLFVFLRIDAG
RGKR

Sequences:

>Translated_484_residues
MAYTNDSIWKSVDWMTICIYLMLVIFGWFSVCGASYDYGEIDFFSFDTRAGKQFVWICCSLGLGFILMMLEDKLYDMFAY
ILYGGMMLLLLITPFLAEDTKGSYSWIKFGPVSLQPAEFAKFATALALAKFMNVYGFTMSKLKYSLPVVGMVLLPMLLII
LQRETGSALVYLAFFFMLYREGMPGSILFAGICAVVYFVVGIRFGNELMADDCTSIGEFSVLLLIVILSALLVNSYCKKA
SVVWYIGGIGVGGTLLALLFSYYVIPFDITWFQYGLCVVLLFYLIFLSMHERMRNYFYIALFAIGSVGFLFSADYVFNNV
LEPHQQIRIKVVLGMEEDLAGAGYNVNQSKIAIGSGGLWGKGFLNGTQTKLKYVPEQDTDFIFCTVGEEEGFVGSAAVLF
LFTGLILRLIVVAERQHTRFARVYGYSVLSIFLFHLFINIGMVLGLTPVIGIPLPFFSYGGSSLWGFTILLFVFLRIDAG
RGKR
>Mature_483_residues
AYTNDSIWKSVDWMTICIYLMLVIFGWFSVCGASYDYGEIDFFSFDTRAGKQFVWICCSLGLGFILMMLEDKLYDMFAYI
LYGGMMLLLLITPFLAEDTKGSYSWIKFGPVSLQPAEFAKFATALALAKFMNVYGFTMSKLKYSLPVVGMVLLPMLLIIL
QRETGSALVYLAFFFMLYREGMPGSILFAGICAVVYFVVGIRFGNELMADDCTSIGEFSVLLLIVILSALLVNSYCKKAS
VVWYIGGIGVGGTLLALLFSYYVIPFDITWFQYGLCVVLLFYLIFLSMHERMRNYFYIALFAIGSVGFLFSADYVFNNVL
EPHQQIRIKVVLGMEEDLAGAGYNVNQSKIAIGSGGLWGKGFLNGTQTKLKYVPEQDTDFIFCTVGEEEGFVGSAAVLFL
FTGLILRLIVVAERQHTRFARVYGYSVLSIFLFHLFINIGMVLGLTPVIGIPLPFFSYGGSSLWGFTILLFVFLRIDAGR
GKR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=145, Percent_Identity=48.9655172413793, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786277, Length=160, Percent_Identity=38.125, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 54252; Mature: 54121

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYTNDSIWKSVDWMTICIYLMLVIFGWFSVCGASYDYGEIDFFSFDTRAGKQFVWICCS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
LGLGFILMMLEDKLYDMFAYILYGGMMLLLLITPFLAEDTKGSYSWIKFGPVSLQPAEFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
KFATALALAKFMNVYGFTMSKLKYSLPVVGMVLLPMLLIILQRETGSALVYLAFFFMLYR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EGMPGSILFAGICAVVYFVVGIRFGNELMADDCTSIGEFSVLLLIVILSALLVNSYCKKA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
SVVWYIGGIGVGGTLLALLFSYYVIPFDITWFQYGLCVVLLFYLIFLSMHERMRNYFYIA
CEEEEECCCCCHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFAIGSVGFLFSADYVFNNVLEPHQQIRIKVVLGMEEDLAGAGYNVNQSKIAIGSGGLWG
HHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCHHCCCCCCCCCCCEEEEECCCCCC
KGFLNGTQTKLKYVPEQDTDFIFCTVGEEEGFVGSAAVLFLFTGLILRLIVVAERQHTRF
CCCCCCCCHHEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVYGYSVLSIFLFHLFINIGMVLGLTPVIGIPLPFFSYGGSSLWGFTILLFVFLRIDAG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCC
RGKR
CCCC
>Mature Secondary Structure 
AYTNDSIWKSVDWMTICIYLMLVIFGWFSVCGASYDYGEIDFFSFDTRAGKQFVWICCS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHH
LGLGFILMMLEDKLYDMFAYILYGGMMLLLLITPFLAEDTKGSYSWIKFGPVSLQPAEFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHH
KFATALALAKFMNVYGFTMSKLKYSLPVVGMVLLPMLLIILQRETGSALVYLAFFFMLYR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
EGMPGSILFAGICAVVYFVVGIRFGNELMADDCTSIGEFSVLLLIVILSALLVNSYCKKA
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
SVVWYIGGIGVGGTLLALLFSYYVIPFDITWFQYGLCVVLLFYLIFLSMHERMRNYFYIA
CEEEEECCCCCHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFAIGSVGFLFSADYVFNNVLEPHQQIRIKVVLGMEEDLAGAGYNVNQSKIAIGSGGLWG
HHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCHHCCCCCCCCCCCEEEEECCCCCC
KGFLNGTQTKLKYVPEQDTDFIFCTVGEEEGFVGSAAVLFLFTGLILRLIVVAERQHTRF
CCCCCCCCHHEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVYGYSVLSIFLFHLFINIGMVLGLTPVIGIPLPFFSYGGSSLWGFTILLFVFLRIDAG
HHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCC
RGKR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]