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The map label for this gene is exuT [H]

Identifier: 150004348

GI number: 150004348

Start: 2311710

End: 2313185

Strand: Reverse

Name: exuT [H]

Synonym: BVU_1794

Alternate gene names: 150004348

Gene position: 2313185-2311710 (Counterclockwise)

Preceding gene: 150004349

Following gene: 150004332

Centisome position: 44.8

GC content: 42.62

Gene sequence:

>1476_bases
ATGAGTACATTTCAAAAAGTAGGTGAGAAGATGACAAACTTCAGATGGATAATCTGTGGTCTGCTATTCTTTGCCACTAC
AGTCAATTACCTCGACCGTCAGGTGCTTTCACTAACCTGGAAAGACTTCATTGCTCCGGAATTTCACTGGACGGATTCGA
ATTACGGAGATATCACAGCTATTTTCTCTATAGTGTATGCCATTGCCAACCTGTTCGCCGGTCGTTTCATTGACTGGATG
GGAACTAAAAAAGGTTATCTCTGGGCTATCTTTGTCTGGTCCTTAGGAGCTTGTCTTCATGCATTGTGCGGTTGGGCAAC
CGAAGAAACATTAGGTATTCATAACGCAGAAGAGATGCTTTCTGCAACAGGAGCCGTCGCTTCAACTATCGCTATTACCA
GCGTTTATTACTTTATCGCTGCCCGAATCGTATTAGGTGTAGGTGAGGCAGGAAACTTCCCAGCAGCTATTAAGGTAACA
GCCGAATATTTTCCGAAAAAGGACCGTGCATATTCCACTTCCATCTTTAATGCAGGTTCTACAGTAGGTGCTTTAGCCGC
TCCGATCACTATTCCTCCTTTGGCACGTTATTTCCAAAGTATTGGTGTGGGCAACGGATGGGAAATGGCTTTCATCGTTA
TCGGTGGTTTAGGATTCATTTGGATGGGACTTTGGATGTTCCTCTATAAGAAACCCAATGTCAACCCTCGCGTGAATGCT
GCCGAACTGGAATATATCGAACAAGACAACAACAATCCTGAAGAATCAGCAGAACAACAAGCTGCTGCCAACGACTTCGA
CAACAAGAAGATTTCATTCTTGCAATGTTTCAAATTTCCCCAAACATGGGCTGTATTTGTCGGTAAGTTCATGACTGATG
GCGTATGGTGGTTCTTCCTGTTCTGGACTCCGGCATATATTTCGGATGTATACGGTTTCGCTTCAGATACGGGTACCGCA
CAAATGTTGATTTTCGTATTATATGCTATTACCATGTTATCTATTTATGGTGGTAAGTTACCTACTATTATCATTAATAA
AACAGGTAAGAATCCATATGCAGCCCGTATGCAGGCTATGCTTATCTTTGCCTTGTTCCCACTGCTGGCATTGTTTGCCC
AACCTTTAGGCAATTATTCATATTGGTATCCTATCATTATTATCGGTATTGCAGGTGCTGCACACCAATCATGGTCTGCC
AATATTTATTCTGTAGTAGGTGATATGTTCCCCAAAAGCACCATCGCTACTATCGTAGGTATTGGTGGTATGGCAGGTGG
TATAGGTTCATTCTGTATTAATATGGGATCTGGCAGACTGTTTGACTATGCAGCAGAAACGAATATGACTTTTATGGGAT
TCGAAGGAAAACCTGCCGGCTACTTCATCATATTCTGTGTATGTGCCGTAGCTTATTTGGTTGGTTGGATTATCATGAAA
GCATTGGTCCCCAAATACAAACCGGTTGATGCCTAA

Upstream 100 bases:

>100_bases
TACCGATTTATACAGGCTTTCCACCAATTTTTGCATAGAGAATAGGTACAGAATGGTTATTTTTGCGTCTAATAAGAAAA
ACATAATTAAATCTATTATC

Downstream 100 bases:

>100_bases
TTAAAGAATTCACCACAGACTACACACCTAAGTAGCCTGTGGTATTTTTTTCCCTAATAAATAGTTTTCAGAAGATATTG
ATAGATAGAATTATGACTTA

Product: hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSTFQKVGEKMTNFRWIICGLLFFATTVNYLDRQVLSLTWKDFIAPEFHWTDSNYGDITAIFSIVYAIANLFAGRFIDWM
GTKKGYLWAIFVWSLGACLHALCGWATEETLGIHNAEEMLSATGAVASTIAITSVYYFIAARIVLGVGEAGNFPAAIKVT
AEYFPKKDRAYSTSIFNAGSTVGALAAPITIPPLARYFQSIGVGNGWEMAFIVIGGLGFIWMGLWMFLYKKPNVNPRVNA
AELEYIEQDNNNPEESAEQQAAANDFDNKKISFLQCFKFPQTWAVFVGKFMTDGVWWFFLFWTPAYISDVYGFASDTGTA
QMLIFVLYAITMLSIYGGKLPTIIINKTGKNPYAARMQAMLIFALFPLLALFAQPLGNYSYWYPIIIIGIAGAAHQSWSA
NIYSVVGDMFPKSTIATIVGIGGMAGGIGSFCINMGSGRLFDYAAETNMTFMGFEGKPAGYFIIFCVCAVAYLVGWIIMK
ALVPKYKPVDA

Sequences:

>Translated_491_residues
MSTFQKVGEKMTNFRWIICGLLFFATTVNYLDRQVLSLTWKDFIAPEFHWTDSNYGDITAIFSIVYAIANLFAGRFIDWM
GTKKGYLWAIFVWSLGACLHALCGWATEETLGIHNAEEMLSATGAVASTIAITSVYYFIAARIVLGVGEAGNFPAAIKVT
AEYFPKKDRAYSTSIFNAGSTVGALAAPITIPPLARYFQSIGVGNGWEMAFIVIGGLGFIWMGLWMFLYKKPNVNPRVNA
AELEYIEQDNNNPEESAEQQAAANDFDNKKISFLQCFKFPQTWAVFVGKFMTDGVWWFFLFWTPAYISDVYGFASDTGTA
QMLIFVLYAITMLSIYGGKLPTIIINKTGKNPYAARMQAMLIFALFPLLALFAQPLGNYSYWYPIIIIGIAGAAHQSWSA
NIYSVVGDMFPKSTIATIVGIGGMAGGIGSFCINMGSGRLFDYAAETNMTFMGFEGKPAGYFIIFCVCAVAYLVGWIIMK
ALVPKYKPVDA
>Mature_490_residues
STFQKVGEKMTNFRWIICGLLFFATTVNYLDRQVLSLTWKDFIAPEFHWTDSNYGDITAIFSIVYAIANLFAGRFIDWMG
TKKGYLWAIFVWSLGACLHALCGWATEETLGIHNAEEMLSATGAVASTIAITSVYYFIAARIVLGVGEAGNFPAAIKVTA
EYFPKKDRAYSTSIFNAGSTVGALAAPITIPPLARYFQSIGVGNGWEMAFIVIGGLGFIWMGLWMFLYKKPNVNPRVNAA
ELEYIEQDNNNPEESAEQQAAANDFDNKKISFLQCFKFPQTWAVFVGKFMTDGVWWFFLFWTPAYISDVYGFASDTGTAQ
MLIFVLYAITMLSIYGGKLPTIIINKTGKNPYAARMQAMLIFALFPLLALFAQPLGNYSYWYPIIIIGIAGAAHQSWSAN
IYSVVGDMFPKSTIATIVGIGGMAGGIGSFCINMGSGRLFDYAAETNMTFMGFEGKPAGYFIIFCVCAVAYLVGWIIMKA
LVPKYKPVDA

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI2367193, Length=443, Percent_Identity=27.0880361173815, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789152, Length=306, Percent_Identity=26.1437908496732, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789515, Length=307, Percent_Identity=27.0358306188925, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI87082320, Length=307, Percent_Identity=25.7328990228013, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI2367379, Length=318, Percent_Identity=28.3018867924528, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17552542, Length=337, Percent_Identity=21.0682492581602, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=282, Percent_Identity=21.6312056737589, Blast_Score=65, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24641682, Length=204, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 54263; Mature: 54131

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTFQKVGEKMTNFRWIICGLLFFATTVNYLDRQVLSLTWKDFIAPEFHWTDSNYGDITA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHH
IFSIVYAIANLFAGRFIDWMGTKKGYLWAIFVWSLGACLHALCGWATEETLGIHNAEEML
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHH
SATGAVASTIAITSVYYFIAARIVLGVGEAGNFPAAIKVTAEYFPKKDRAYSTSIFNAGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHCCCC
TVGALAAPITIPPLARYFQSIGVGNGWEMAFIVIGGLGFIWMGLWMFLYKKPNVNPRVNA
CHHHHHCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AELEYIEQDNNNPEESAEQQAAANDFDNKKISFLQCFKFPQTWAVFVGKFMTDGVWWFFL
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FWTPAYISDVYGFASDTGTAQMLIFVLYAITMLSIYGGKLPTIIINKTGKNPYAARMQAM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LIFALFPLLALFAQPLGNYSYWYPIIIIGIAGAAHQSWSANIYSVVGDMFPKSTIATIVG
HHHHHHHHHHHHHHHCCCCCCEEEEHEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
IGGMAGGIGSFCINMGSGRLFDYAAETNMTFMGFEGKPAGYFIIFCVCAVAYLVGWIIMK
CCCCCCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ALVPKYKPVDA
HHCCCCCCCCC
>Mature Secondary Structure 
STFQKVGEKMTNFRWIICGLLFFATTVNYLDRQVLSLTWKDFIAPEFHWTDSNYGDITA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHH
IFSIVYAIANLFAGRFIDWMGTKKGYLWAIFVWSLGACLHALCGWATEETLGIHNAEEML
HHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHH
SATGAVASTIAITSVYYFIAARIVLGVGEAGNFPAAIKVTAEYFPKKDRAYSTSIFNAGS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHCCCCCCCHHHHHHCCCC
TVGALAAPITIPPLARYFQSIGVGNGWEMAFIVIGGLGFIWMGLWMFLYKKPNVNPRVNA
CHHHHHCCCCCHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AELEYIEQDNNNPEESAEQQAAANDFDNKKISFLQCFKFPQTWAVFVGKFMTDGVWWFFL
HHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FWTPAYISDVYGFASDTGTAQMLIFVLYAITMLSIYGGKLPTIIINKTGKNPYAARMQAM
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHH
LIFALFPLLALFAQPLGNYSYWYPIIIIGIAGAAHQSWSANIYSVVGDMFPKSTIATIVG
HHHHHHHHHHHHHHHCCCCCCEEEEHEEEECCCCCCCCCCHHHHHHHHHCCHHHHHHHHH
IGGMAGGIGSFCINMGSGRLFDYAAETNMTFMGFEGKPAGYFIIFCVCAVAYLVGWIIMK
CCCCCCCHHHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
ALVPKYKPVDA
HHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]