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The map label for this gene is nuoN

Identifier: 150004304

GI number: 150004304

Start: 2246660

End: 2248078

Strand: Reverse

Name: nuoN

Synonym: BVU_1750

Alternate gene names: 150004304

Gene position: 2248078-2246660 (Counterclockwise)

Preceding gene: 150004305

Following gene: 150004303

Centisome position: 43.54

GC content: 42.0

Gene sequence:

>1419_bases
ATGGACATAACTGCAATACTCCATATGCATGCCGAACTGAGTCTGACAGCCGTTTTTATTCTGATGTTTCTGTTAGATTT
ATTTTTACCGGCAACACAACGTCACTGGTTACGCCCCATGGCATGTATCCTGCTGACCATTCAACTCTTAGCAAACCTAT
GGCCGGAAGAGGTGACTTTATTTGGCGGCATGTACCACTCAACCCCTATGGCGTCTGTTCTAAAAAGCATCCTTACCATA
GGTACCATACTGGTGTTCCTACAAGCAGACACTTGGCTAAAACGTGAAGACACCCGCCATAAACAAGGCGAATTCTACAT
CCTTACCCTCAGTACCTTGCTGGGTATGTATTTCATGGTAAGCGCAGGGCACTTCCTGCTATTCTTCCTTGGATTGGAAT
TGGCAACCGTTCCTATGGCTTGTCTCGTAGCTTTCGATAAATATAAAGGACATAGTGCCGAAGCCGGAGCTAAATTCATT
CTTTCGGCTTTATTCTCCAGCGGTATTTTCCTCTATGGTATTTCTATGATTTATGGGACAGCAGGTACTTTATATTTTGA
AGATATCCCTGCCGGATTGACAGGAACTCCATTACAAGTTCTTGCACTAGTATTTTTCTTCTCCGGACTGGCCTTCAAGT
TAAGCTTGGTACCTTTTCATCTGTGGACAGCAGATACTTATCAAGGTGCACCGACTACAGTAAGCGCCTACCTATCCGTT
ATTTCAAAAGGTGCAGCTGCTTTTGCTTTAATGATTATTTTAATGAAAGTATTCGGACCAATGACTGAACAATGGAGTGA
AATACTATGTATTATCATTGTAGCCACCATCACTATAGCCAATCTGTTCGCCATCCGCCAAAACAACCTGAAACGCTTTA
TGGCCTTCAGTAGTATTTCACAAGCCGGCTACATAATGTTGGCTGTACTGGCTGGAACTCCGCAGGACATGGCATCCCTA
GTATATTATATAGTAGTATACATTGCCGCCAATCTCGCCGTATTCGGTGTCATCAGTACCATTGAGCAACATACCCACGG
TAAAATAGAGCGCGAAGATTATAACGGACTTTATAAGACCAACCCCAAACTAACTATGGTCATGACACTTGCTCTTTTCT
CATTGGCAGGTATCCCGCCATTTGCCGGATTCTTCAGTAAGTTCTTTGTATTCATGGCAGCATTCCATAGCGGATATTAT
CTTATTGTATTTATCGCATTGGTCAATACAATCATTTCATTGTATTATTACTTATTGATTGTAAAAGCCATGTTCATCAC
ACCTAATGAAGACCCTATCGGCAATTTTCGTACAGCAACTCCGATGCGCATCAGTCTGTTGGTATGTGTAGCCGGCATAT
TCGTTTTAGGAATTATAAGTGGGGTATATCAACTATTAAGTGATACAGCAATACTATAA

Upstream 100 bases:

>100_bases
TCCATTCTGGATAAGCGATCTGATCAGTAACAGTGTAGAACCAATCATAAGTCAATTATTAAATTAAAATTTGAGAATTA
AAAATTAAAAAATAGCAATG

Downstream 100 bases:

>100_bases
AAGTTCAGTTACAAAAAGAAGAATAATAACTGAAATGATTATTATATTTCTATGATCAATATTCTTTTACTTTGGAGGCA
GAATCAATCTGTTTCCAAAG

Product: NADH dehydrogenase I chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTI
GTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMVSAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFI
LSALFSSGIFLYGISMIYGTAGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSV
ISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQDMASL
VYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYY
LIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL

Sequences:

>Translated_472_residues
MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTI
GTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMVSAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFI
LSALFSSGIFLYGISMIYGTAGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSV
ISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQDMASL
VYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYY
LIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL
>Mature_472_residues
MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTLFGGMYHSTPMASVLKSILTI
GTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMVSAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFI
LSALFSSGIFLYGISMIYGTAGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSV
ISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSISQAGYIMLAVLAGTPQDMASL
VYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKTNPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYY
LIVFIALVNTIISLYYYLLIVKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=356, Percent_Identity=34.5505617977528, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788831, Length=325, Percent_Identity=24.6153846153846, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788613, Length=314, Percent_Identity=23.5668789808917, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788614, Length=352, Percent_Identity=23.5795454545455, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1788829, Length=189, Percent_Identity=28.042328042328, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_BACV8 (A6L162)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001299048.1
- STRING:   A6L162
- GeneID:   5302716
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1750
- NMPDR:   fig|435590.6.peg.1647
- HOGENOM:   HBG747830
- OMA:   AMWIESP
- ProtClustDB:   CLSK823765
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 52170; Mature: 52170

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1bba8b80)-; HASH(0x1c9f5bfc)-; HASH(0x1c9f5ac4)-; HASH(0x1c9dc2e0)-; HASH(0x19510eb4)-; HASH(0x19510ed8)-; HASH(0x1c9f8f9c)-; HASH(0x1c9f5a88)-; HASH(0x1c9f90e0)-; HASH(0x1c9f5cbc)-; HASH(0x1c9f9128)-; HASH(0x1be064a8)-; HASH(0x1bec70bc)-; HASH(0x19511010)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FGGMYHSTPMASVLKSILTIGTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMV
HCCHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
SAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFILSALFSSGIFLYGISMIYGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
AGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSV
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHH
ISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAGYIMLAVLAGTPQDMASLVYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKT
HCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEC
NPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYYLIVFIALVNTIISLYYYLLI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MDITAILHMHAELSLTAVFILMFLLDLFLPATQRHWLRPMACILLTIQLLANLWPEEVTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FGGMYHSTPMASVLKSILTIGTILVFLQADTWLKREDTRHKQGEFYILTLSTLLGMYFMV
HCCHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCEEEEEHHHHHHHHHHH
SAGHFLLFFLGLELATVPMACLVAFDKYKGHSAEAGAKFILSALFSSGIFLYGISMIYGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
AGTLYFEDIPAGLTGTPLQVLALVFFFSGLAFKLSLVPFHLWTADTYQGAPTTVSAYLSV
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHH
ISKGAAAFALMIILMKVFGPMTEQWSEILCIIIVATITIANLFAIRQNNLKRFMAFSSIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAGYIMLAVLAGTPQDMASLVYYIVVYIAANLAVFGVISTIEQHTHGKIEREDYNGLYKT
HCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCEEC
NPKLTMVMTLALFSLAGIPPFAGFFSKFFVFMAAFHSGYYLIVFIALVNTIISLYYYLLI
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
VKAMFITPNEDPIGNFRTATPMRISLLVCVAGIFVLGIISGVYQLLSDTAIL
HHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA