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The map label for this gene is paaK [H]

Identifier: 150004227

GI number: 150004227

Start: 2155796

End: 2157094

Strand: Reverse

Name: paaK [H]

Synonym: BVU_1668

Alternate gene names: 150004227

Gene position: 2157094-2155796 (Counterclockwise)

Preceding gene: 150004229

Following gene: 150004226

Centisome position: 41.78

GC content: 48.27

Gene sequence:

>1299_bases
ATGTATTTACACAAAGAGTTAGAGACCCTGACACGACCCGAAATTGAGAAACTACAATTGGAACGACTGCAAAAGACTGT
CCGCCATTGCATGAATTCCCCTTTCTATAAACAACGGTTTGCCGAAAATCATCTGAGTCCGGAAGATATCCGTTCATTGG
ATGATTTACAGAAAATCCCGTTTACCACCAAACAAGATCTACGTGACACTTATCCTTTCGGACTGGCGTCCGTACCTTTG
GAAAAAACAGTCCGCCTTCACTCATCCAGTGGAACAACCGGAAATCCCACTGTCATTCTGCATACCCAAAAAGACCTTGA
CGAATGGGCTAATGCAGTGGCCCGTTGTCTTTATATGGTAGGATTACGTCCGGGAGATATTTTCCAGAACTCTTCCGGCT
ATGGAATGTTCACCGGCGGGCTGGGCTTTCAATATGGTGCTGAAAGGCTGGGAATGCTGACTGTACCTGCCGCTGCCGGA
AACACCAAACGCCAGTTGAAATTCATCTCCGATTTCGGAACCACCGCCTTGCACGCCATTCCCAGTTACGCAGCCCGTAT
GTACGAGATAATGCAGGAAATGGGGATTGATCCGCGTCGTGACACCAAATTGAGAACATTGATCATAGGAGCGGAACCTC
ATTCCGAAGAACAACGCCGCCGCATCGAAGATATGCTGGGTGTAAAAGCCTACAACTCTTTCGGCATGTCCGAAATGTGC
GGTCCCGGTGTGGCTTTTGAATGCCAGGAACAAAACGGATTGCATATATGGGAAGACTATTATATCGTAGAAATCATCGA
CCCCGACACATTGGAACCTGTGCCCGAGGGTGAAGTGGGCGAACTGGTACTGACCACCATCAACCGCGAGGCGATGCCGT
TATTGAGATACCGTACCCGTGATCTGACCCGCATTCTGCCGGGGGAATGCCCCTGCGGCCGCCATCACAAACGTCTGGAC
AGAATGAAAGGGCGCAGCGACGATATGATTATCCTGAAAGGGGTCAATATCTTCCCCATTCAGATTGAAACGATTTTATT
GCAATTCAAAGAATTGGGCAGTGACTATCTGATCACACTCGAAACCGCCGAATCTAATGACGAAATGACTGTAGAAGTGG
AATTGAGCCAACTGTTCACCGATGACTATGGACGCCTGCAAGCATTGACCCGGGAAATTACCCGCCAACTGAAAGATGAG
ATATTGGTTACCCCACGTGTGAAACTGGTACCCAAAGGAGCACTGCCTAAATCGGAAGGTAAAGCAGTCCGTGTGAAAGA
CTTACGTAAAACCTTTTAA

Upstream 100 bases:

>100_bases
TAAAATCCTCCAAAGATACATATTTTGTCAGCTTATTCCCAACCGCATTATATTTTTTTCTATTTTTGTCGGACTGATAA
CCAACTAAACAGGAAATGCT

Downstream 100 bases:

>100_bases
AAAATAAGTTTATGACTATACAACAATTATCCGTCTTCATCGAAAACAAATCGGGGACACTACAGAAAGTATTGAACTTA
TTGAAAGAAGCAGGCATACA

Product: phenylacetate-coenzyme A ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MYLHKELETLTRPEIEKLQLERLQKTVRHCMNSPFYKQRFAENHLSPEDIRSLDDLQKIPFTTKQDLRDTYPFGLASVPL
EKTVRLHSSSGTTGNPTVILHTQKDLDEWANAVARCLYMVGLRPGDIFQNSSGYGMFTGGLGFQYGAERLGMLTVPAAAG
NTKRQLKFISDFGTTALHAIPSYAARMYEIMQEMGIDPRRDTKLRTLIIGAEPHSEEQRRRIEDMLGVKAYNSFGMSEMC
GPGVAFECQEQNGLHIWEDYYIVEIIDPDTLEPVPEGEVGELVLTTINREAMPLLRYRTRDLTRILPGECPCGRHHKRLD
RMKGRSDDMIILKGVNIFPIQIETILLQFKELGSDYLITLETAESNDEMTVEVELSQLFTDDYGRLQALTREITRQLKDE
ILVTPRVKLVPKGALPKSEGKAVRVKDLRKTF

Sequences:

>Translated_432_residues
MYLHKELETLTRPEIEKLQLERLQKTVRHCMNSPFYKQRFAENHLSPEDIRSLDDLQKIPFTTKQDLRDTYPFGLASVPL
EKTVRLHSSSGTTGNPTVILHTQKDLDEWANAVARCLYMVGLRPGDIFQNSSGYGMFTGGLGFQYGAERLGMLTVPAAAG
NTKRQLKFISDFGTTALHAIPSYAARMYEIMQEMGIDPRRDTKLRTLIIGAEPHSEEQRRRIEDMLGVKAYNSFGMSEMC
GPGVAFECQEQNGLHIWEDYYIVEIIDPDTLEPVPEGEVGELVLTTINREAMPLLRYRTRDLTRILPGECPCGRHHKRLD
RMKGRSDDMIILKGVNIFPIQIETILLQFKELGSDYLITLETAESNDEMTVEVELSQLFTDDYGRLQALTREITRQLKDE
ILVTPRVKLVPKGALPKSEGKAVRVKDLRKTF
>Mature_432_residues
MYLHKELETLTRPEIEKLQLERLQKTVRHCMNSPFYKQRFAENHLSPEDIRSLDDLQKIPFTTKQDLRDTYPFGLASVPL
EKTVRLHSSSGTTGNPTVILHTQKDLDEWANAVARCLYMVGLRPGDIFQNSSGYGMFTGGLGFQYGAERLGMLTVPAAAG
NTKRQLKFISDFGTTALHAIPSYAARMYEIMQEMGIDPRRDTKLRTLIIGAEPHSEEQRRRIEDMLGVKAYNSFGMSEMC
GPGVAFECQEQNGLHIWEDYYIVEIIDPDTLEPVPEGEVGELVLTTINREAMPLLRYRTRDLTRILPGECPCGRHHKRLD
RMKGRSDDMIILKGVNIFPIQIETILLQFKELGSDYLITLETAESNDEMTVEVELSQLFTDDYGRLQALTREITRQLKDE
ILVTPRVKLVPKGALPKSEGKAVRVKDLRKTF

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=429, Percent_Identity=44.0559440559441, Blast_Score=364, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 49226; Mature: 49226

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLHKELETLTRPEIEKLQLERLQKTVRHCMNSPFYKQRFAENHLSPEDIRSLDDLQKIP
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
FTTKQDLRDTYPFGLASVPLEKTVRLHSSSGTTGNPTVILHTQKDLDEWANAVARCLYMV
CCCHHHHHHCCCCCCCCCCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
GLRPGDIFQNSSGYGMFTGGLGFQYGAERLGMLTVPAAAGNTKRQLKFISDFGTTALHAI
CCCCCHHCCCCCCCEEEECCCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHH
PSYAARMYEIMQEMGIDPRRDTKLRTLIIGAEPHSEEQRRRIEDMLGVKAYNSFGMSEMC
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHC
GPGVAFECQEQNGLHIWEDYYIVEIIDPDTLEPVPEGEVGELVLTTINREAMPLLRYRTR
CCCCEEEECCCCCCEEEECEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
DLTRILPGECPCGRHHKRLDRMKGRSDDMIILKGVNIFPIQIETILLQFKELGSDYLITL
HHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCEEEEEHHHHHHHHHHHCCCCEEEEE
ETAESNDEMTVEVELSQLFTDDYGRLQALTREITRQLKDEILVTPRVKLVPKGALPKSEG
EECCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCCC
KAVRVKDLRKTF
CEEEHHHHHHCC
>Mature Secondary Structure
MYLHKELETLTRPEIEKLQLERLQKTVRHCMNSPFYKQRFAENHLSPEDIRSLDDLQKIP
CCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
FTTKQDLRDTYPFGLASVPLEKTVRLHSSSGTTGNPTVILHTQKDLDEWANAVARCLYMV
CCCHHHHHHCCCCCCCCCCHHHHHEEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
GLRPGDIFQNSSGYGMFTGGLGFQYGAERLGMLTVPAAAGNTKRQLKFISDFGTTALHAI
CCCCCHHCCCCCCCEEEECCCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHCCHHHHHHH
PSYAARMYEIMQEMGIDPRRDTKLRTLIIGAEPHSEEQRRRIEDMLGVKAYNSFGMSEMC
HHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHC
GPGVAFECQEQNGLHIWEDYYIVEIIDPDTLEPVPEGEVGELVLTTINREAMPLLRYRTR
CCCCEEEECCCCCCEEEECEEEEEEECCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHH
DLTRILPGECPCGRHHKRLDRMKGRSDDMIILKGVNIFPIQIETILLQFKELGSDYLITL
HHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCEEEEEHHHHHHHHHHHCCCCEEEEE
ETAESNDEMTVEVELSQLFTDDYGRLQALTREITRQLKDEILVTPRVKLVPKGALPKSEG
EECCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCEEEEECCCCCCCCC
KAVRVKDLRKTF
CEEEHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]