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The map label for this gene is fkp

Identifier: 150004170

GI number: 150004170

Start: 2090482

End: 2093322

Strand: Direct

Name: fkp

Synonym: BVU_1606

Alternate gene names: NA

Gene position: 2090482-2093322 (Clockwise)

Preceding gene: 150004169

Following gene: 150004172

Centisome position: 40.49

GC content: 46.67

Gene sequence:

>2841_bases
ATGAAAAAATTATTATCACTTCCCCCTAATCTGGTGGAATGTTTTCATGATATAGAGAAAGCGGACCAGACAGAGTGGTT
TTGTACTTCCGATCCTATAGGTAGTAAGCTAGGATCAGGCGGGGGGACTGCATGGCTGTTGGAGGCTTGTTGTCAGAAAG
TAGCTCCTGACAGCGATTTTCTTACTTGGCTGGGAAAAGAAAAACGTATTTTACTTCATGCAGGCGGGCAGAGTCGTCGT
TTGCCCGGATATGCGCCATCCGGCAAAATTCTTACTCCCATTCCTGTATTCCGGTGGGCCAGAGGACAACGGCTGTCACA
AAATCTGCTTTCCCTCCAGCTCCCTTTATATGAACAAATCATGGAGAAAGCTCCGTCTTCTCTTCATACATTGATTGCAA
GTGGAGATGTTTATATCCGTGCGGGCCAACCGCTTCAGACTATTCCTGATGCGGATGTGGTGTGTTACGGTTTATGGGTA
GATCCTAATCTGGCAAAAAACCATGGTGTTTTTGTTTCTTCACGGGCTACTCCCGATAAGCTTGATTTCATGCTTCAAAA
ACCTTCGGTGGAGGAATTGGGGAAATTAATGCAAACCCATCTTTTTCTGATGGATATCGGAATTTGGCTGTTAAGTGACC
GTGCGGTTAGTCTGTTGGTAAAACGATCTTATAAGGAAGGAAAACTCTCTTATTATGACATGTATTCTGATTTCGGACTT
ACATTGGGAGAGCACCCGCGTATGATGGACGATGAACTTAACAAGCTGAGTGTGGCTATTCTGCCGTTGCCCGGAGGGGA
GTTTTATCATTACGGAACCAGTCGTGAACTTATTTCTTCTACATTGGCAGTACAAAATCTGGTAAACGACCAGCGGGAGA
TTATGCACAAGAAGGTAAAACCGCATCCGGCCATGTTTGTTCAAAATGCTGAGGTAGGTTATCAACTTACCTCACAAAAT
TCGGAAATATGGATAGAGAACAGTTATGTAGGAGCAGGATGGAATATCCATCACCAGACCATCATAACAGGGGTTCCCGC
TAATAATTGGAACCTAGAGGTTCCGTCCGGTGTGTGTATTGATGTGGTTCCTTTTGGAGAATCTGGCTATGTAGCGCGTC
CATACGGCTTCAATGATACTTTCAAGGGAGCTTTGGCTAAGGAAGAAACATATTATCAAGGAATGTCTGTAGGTGAGTGG
TGTGCTGTACGCGGCATTTCGGTGGAAGAAATAGAAAACGGTCACGACTTGCAGGCCGCGCGTTTGTTTCCGGTTTGCTC
ATCTGTAGAGGAATTGGGAGCAGTTATGCGCTGGATGGTCTCTGAACCGGCATTACAGCAAGGAAAAGAAATATGGCAAC
GCTGTCGTAAGTTATCTGCCGATGATATATCTGCTTATTCTAATCTTTATCGTCTGGCAGAACAGCGTGAAGCTTTCCGG
ATAAAGAATTGGCCGGCATTGGCGCATAATTATGAACGAAGTGTCTTTTATCAGCTAAATTTGGAGAATGCTGCTGGAGA
ATTTGCTCGGTATGATCTGTCGTTGCCTGAGCCTTTATCAGAATCGGCTCCGCTGATGACACGTATCAGTGATAATATGT
TTCGTGCCCGGGTGCAGCAGCTTAAGGGGCTGGCTTATCGGGAATATGAGAATGAGGCTTTTCGTTTGATGCGCGACGGA
CTTACTGCTTCGGCTTTAGCCAAGAGGCAGCAACCGCATTTGTCAGTGTACTCCGATCAGATTGTCTGGGGGCGTAGTCC
GGTCCGTATTGATCTGGCCGGCGGATGGACGGATACTCCACCTTATTGCTTGAATGAAGGGGGGAATGTGGTGAATATTG
CTATTGAGTTGAACGGGCAGCCTCCTCTACAAGTTTACGTGAAACCCTGTCGGGAGTATAAGATAATTCTTCGTTCTATA
GACTTAGGCGCTATGGAAGTGGTTACAACTTACGGGGAGGTAAGGGATTTCATGCAAGTGGGATCCCCATTCTCTATACC
TAAAGCGGCATTGGTGCTGGCAGGTTTCCAGCCGGGCTTTTCCACCGAATCGTATGTTTCATTGGAAGAGCAGTTGAAGG
CGTTTGGCTCCGGAATGGAAATCACTCTGCTTTCTGCGATTCCTGCGGGCTCCGGTCTGGGTACAAGTTCTATTCTTGCA
TCAACTGTGCTGGGGGCAATCTCTGATTTTTGCGGACTGAACTGGGATAAGAACGAGATATGTAACCGTACGCTTATTTT
GGAACAGTTACTGACTACCGGAGGGGGGTGGCAAGATCAATACGGAGGTGTGCTTCGTGGAGTGAAATTATTGCAGACTC
ATGCAGGTATGGATCAGAGTCCGTTAGTGCGCTGGTTGCCCGATTATTTGTTTACAGGTGGCGAATATCAGAAGTGCCAT
TTGCTTTATTACACGGGAATTACCCGTACAGCCAAAGGAATTTTAGCTGAAATCGTGCGTAGCATGTTCCTCAACTCCAC
AGAGCATTTGTCTATACTTGGCGGTATGAAGGGGCATGCTCTTGACTTGTACGAAGCCATTCAGCGTGGGAATTTCGATG
AAATGGGGCGTTTGGTTGGTAAAAGCTGGAAGCTGAACCAAGCGTTGGATCCCGGCACTAATCCCGAGGCAGTTGAGACT
ATCATTCGCCGGATTGATGATTATTGCCTGGGATATAAATTGCCAGGTGCGGGGGGAGGCGGCTATCTTTATATGGTGGC
TAAAGATCCTGAGGCTGCTATACGTATTCGAAGTATTCTTACTCAGAACCCACCCAACAGTTGTGCCCGTTTCGTTGATA
TGGCTTTGTCCGACAAAGGCTTGCAAATTAGCCGAAGCTAG

Upstream 100 bases:

>100_bases
GAGCGTGTTTTTGAATTTACTGATTAAAATTCATGTCTTATCTTTTGGCTTATTAGGGGAAAATAAGCATCTTTGTGTGC
AATAAAAACAAAGATGTGCT

Downstream 100 bases:

>100_bases
TTATAACTGAATAGAGTTGGGAAACCAGCCGGGTGATATTTTCTTTAGCAAACTCCGGTTCCATTGCCTTCTCCAGGGTG
ATGGGGCCGGGGGCTATAGA

Product: bifunctional fucokinase/L-fucose-1-P-guanylyltransferase

Products: NA

Alternate protein names: GHMP Kinase; Sugar Kinase; Capsular Biosynthesis Sugar Kinase; Kinase; Galactokinase And Mevalonate Kinase-Like Protein; D-Glycero-D-Manno-Heptose 7-Phosphate Kinase

Number of amino acids: Translated: 946; Mature: 946

Protein sequence:

>946_residues
MKKLLSLPPNLVECFHDIEKADQTEWFCTSDPIGSKLGSGGGTAWLLEACCQKVAPDSDFLTWLGKEKRILLHAGGQSRR
LPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYEQIMEKAPSSLHTLIASGDVYIRAGQPLQTIPDADVVCYGLWV
DPNLAKNHGVFVSSRATPDKLDFMLQKPSVEELGKLMQTHLFLMDIGIWLLSDRAVSLLVKRSYKEGKLSYYDMYSDFGL
TLGEHPRMMDDELNKLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVNDQREIMHKKVKPHPAMFVQNAEVGYQLTSQN
SEIWIENSYVGAGWNIHHQTIITGVPANNWNLEVPSGVCIDVVPFGESGYVARPYGFNDTFKGALAKEETYYQGMSVGEW
CAVRGISVEEIENGHDLQAARLFPVCSSVEELGAVMRWMVSEPALQQGKEIWQRCRKLSADDISAYSNLYRLAEQREAFR
IKNWPALAHNYERSVFYQLNLENAAGEFARYDLSLPEPLSESAPLMTRISDNMFRARVQQLKGLAYREYENEAFRLMRDG
LTASALAKRQQPHLSVYSDQIVWGRSPVRIDLAGGWTDTPPYCLNEGGNVVNIAIELNGQPPLQVYVKPCREYKIILRSI
DLGAMEVVTTYGEVRDFMQVGSPFSIPKAALVLAGFQPGFSTESYVSLEEQLKAFGSGMEITLLSAIPAGSGLGTSSILA
STVLGAISDFCGLNWDKNEICNRTLILEQLLTTGGGWQDQYGGVLRGVKLLQTHAGMDQSPLVRWLPDYLFTGGEYQKCH
LLYYTGITRTAKGILAEIVRSMFLNSTEHLSILGGMKGHALDLYEAIQRGNFDEMGRLVGKSWKLNQALDPGTNPEAVET
IIRRIDDYCLGYKLPGAGGGGYLYMVAKDPEAAIRIRSILTQNPPNSCARFVDMALSDKGLQISRS

Sequences:

>Translated_946_residues
MKKLLSLPPNLVECFHDIEKADQTEWFCTSDPIGSKLGSGGGTAWLLEACCQKVAPDSDFLTWLGKEKRILLHAGGQSRR
LPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYEQIMEKAPSSLHTLIASGDVYIRAGQPLQTIPDADVVCYGLWV
DPNLAKNHGVFVSSRATPDKLDFMLQKPSVEELGKLMQTHLFLMDIGIWLLSDRAVSLLVKRSYKEGKLSYYDMYSDFGL
TLGEHPRMMDDELNKLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVNDQREIMHKKVKPHPAMFVQNAEVGYQLTSQN
SEIWIENSYVGAGWNIHHQTIITGVPANNWNLEVPSGVCIDVVPFGESGYVARPYGFNDTFKGALAKEETYYQGMSVGEW
CAVRGISVEEIENGHDLQAARLFPVCSSVEELGAVMRWMVSEPALQQGKEIWQRCRKLSADDISAYSNLYRLAEQREAFR
IKNWPALAHNYERSVFYQLNLENAAGEFARYDLSLPEPLSESAPLMTRISDNMFRARVQQLKGLAYREYENEAFRLMRDG
LTASALAKRQQPHLSVYSDQIVWGRSPVRIDLAGGWTDTPPYCLNEGGNVVNIAIELNGQPPLQVYVKPCREYKIILRSI
DLGAMEVVTTYGEVRDFMQVGSPFSIPKAALVLAGFQPGFSTESYVSLEEQLKAFGSGMEITLLSAIPAGSGLGTSSILA
STVLGAISDFCGLNWDKNEICNRTLILEQLLTTGGGWQDQYGGVLRGVKLLQTHAGMDQSPLVRWLPDYLFTGGEYQKCH
LLYYTGITRTAKGILAEIVRSMFLNSTEHLSILGGMKGHALDLYEAIQRGNFDEMGRLVGKSWKLNQALDPGTNPEAVET
IIRRIDDYCLGYKLPGAGGGGYLYMVAKDPEAAIRIRSILTQNPPNSCARFVDMALSDKGLQISRS
>Mature_946_residues
MKKLLSLPPNLVECFHDIEKADQTEWFCTSDPIGSKLGSGGGTAWLLEACCQKVAPDSDFLTWLGKEKRILLHAGGQSRR
LPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYEQIMEKAPSSLHTLIASGDVYIRAGQPLQTIPDADVVCYGLWV
DPNLAKNHGVFVSSRATPDKLDFMLQKPSVEELGKLMQTHLFLMDIGIWLLSDRAVSLLVKRSYKEGKLSYYDMYSDFGL
TLGEHPRMMDDELNKLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVNDQREIMHKKVKPHPAMFVQNAEVGYQLTSQN
SEIWIENSYVGAGWNIHHQTIITGVPANNWNLEVPSGVCIDVVPFGESGYVARPYGFNDTFKGALAKEETYYQGMSVGEW
CAVRGISVEEIENGHDLQAARLFPVCSSVEELGAVMRWMVSEPALQQGKEIWQRCRKLSADDISAYSNLYRLAEQREAFR
IKNWPALAHNYERSVFYQLNLENAAGEFARYDLSLPEPLSESAPLMTRISDNMFRARVQQLKGLAYREYENEAFRLMRDG
LTASALAKRQQPHLSVYSDQIVWGRSPVRIDLAGGWTDTPPYCLNEGGNVVNIAIELNGQPPLQVYVKPCREYKIILRSI
DLGAMEVVTTYGEVRDFMQVGSPFSIPKAALVLAGFQPGFSTESYVSLEEQLKAFGSGMEITLLSAIPAGSGLGTSSILA
STVLGAISDFCGLNWDKNEICNRTLILEQLLTTGGGWQDQYGGVLRGVKLLQTHAGMDQSPLVRWLPDYLFTGGEYQKCH
LLYYTGITRTAKGILAEIVRSMFLNSTEHLSILGGMKGHALDLYEAIQRGNFDEMGRLVGKSWKLNQALDPGTNPEAVET
IIRRIDDYCLGYKLPGAGGGGYLYMVAKDPEAAIRIRSILTQNPPNSCARFVDMALSDKGLQISRS

Specific function: Unknown

COG id: COG2605

COG function: function code R; Predicted kinase related to galactokinase and mevalonate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI63175654, Length=388, Percent_Identity=31.701030927835, Blast_Score=170, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI71982876, Length=295, Percent_Identity=32.5423728813559, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI133901738, Length=357, Percent_Identity=22.6890756302521, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 105143; Mature: 105143

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLSLPPNLVECFHDIEKADQTEWFCTSDPIGSKLGSGGGTAWLLEACCQKVAPDSDF
CCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHH
LTWLGKEKRILLHAGGQSRRLPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYEQI
HHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHCCHHHHHHHHHEECHHHHHH
MEKAPSSLHTLIASGDVYIRAGQPLQTIPDADVVCYGLWVDPNLAKNHGVFVSSRATPDK
HHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCHH
LDFMLQKPSVEELGKLMQTHLFLMDIGIWLLSDRAVSLLVKRSYKEGKLSYYDMYSDFGL
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCC
TLGEHPRMMDDELNKLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVNDQREIMHKKVK
CCCCCCCHHHHCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PHPAMFVQNAEVGYQLTSQNSEIWIENSYVGAGWNIHHQTIITGVPANNWNLEVPSGVCI
CCCCEEEECCCCCEEEECCCCEEEEECCEECCCCEEECEEEEEECCCCCCCEECCCCCEE
DVVPFGESGYVARPYGFNDTFKGALAKEETYYQGMSVGEWCAVRGISVEEIENGHDLQAA
EEEECCCCCCEECCCCCCCCCCCCHHCCHHHHCCCCCCHHHHHCCCCHHHHCCCCCCHHH
RLFPVCSSVEELGAVMRWMVSEPALQQGKEIWQRCRKLSADDISAYSNLYRLAEQREAFR
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHE
IKNWPALAHNYERSVFYQLNLENAAGEFARYDLSLPEPLSESAPLMTRISDNMFRARVQQ
ECCCCHHHCCCCCEEEEEEECCCCCCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKGLAYREYENEAFRLMRDGLTASALAKRQQPHLSVYSDQIVWGRSPVRIDLAGGWTDTP
HHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCCCCCC
PYCLNEGGNVVNIAIELNGQPPLQVYVKPCREYKIILRSIDLGAMEVVTTYGEVRDFMQV
CHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
GSPFSIPKAALVLAGFQPGFSTESYVSLEEQLKAFGSGMEITLLSAIPAGSGLGTSSILA
CCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
STVLGAISDFCGLNWDKNEICNRTLILEQLLTTGGGWQDQYGGVLRGVKLLQTHAGMDQS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PLVRWLPDYLFTGGEYQKCHLLYYTGITRTAKGILAEIVRSMFLNSTEHLSILGGMKGHA
CHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCH
LDLYEAIQRGNFDEMGRLVGKSWKLNQALDPGTNPEAVETIIRRIDDYCLGYKLPGAGGG
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCC
GYLYMVAKDPEAAIRIRSILTQNPPNSCARFVDMALSDKGLQISRS
CEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MKKLLSLPPNLVECFHDIEKADQTEWFCTSDPIGSKLGSGGGTAWLLEACCQKVAPDSDF
CCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHH
LTWLGKEKRILLHAGGQSRRLPGYAPSGKILTPIPVFRWARGQRLSQNLLSLQLPLYEQI
HHHCCCCCEEEEEECCCCCCCCCCCCCCCEECCCHHHHHHCCHHHHHHHHHEECHHHHHH
MEKAPSSLHTLIASGDVYIRAGQPLQTIPDADVVCYGLWVDPNLAKNHGVFVSSRATPDK
HHHCCHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCCCCCCEEEECCCCCHH
LDFMLQKPSVEELGKLMQTHLFLMDIGIWLLSDRAVSLLVKRSYKEGKLSYYDMYSDFGL
HHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHCCC
TLGEHPRMMDDELNKLSVAILPLPGGEFYHYGTSRELISSTLAVQNLVNDQREIMHKKVK
CCCCCCCHHHHCCCEEEEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PHPAMFVQNAEVGYQLTSQNSEIWIENSYVGAGWNIHHQTIITGVPANNWNLEVPSGVCI
CCCCEEEECCCCCEEEECCCCEEEEECCEECCCCEEECEEEEEECCCCCCCEECCCCCEE
DVVPFGESGYVARPYGFNDTFKGALAKEETYYQGMSVGEWCAVRGISVEEIENGHDLQAA
EEEECCCCCCEECCCCCCCCCCCCHHCCHHHHCCCCCCHHHHHCCCCHHHHCCCCCCHHH
RLFPVCSSVEELGAVMRWMVSEPALQQGKEIWQRCRKLSADDISAYSNLYRLAEQREAFR
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHE
IKNWPALAHNYERSVFYQLNLENAAGEFARYDLSLPEPLSESAPLMTRISDNMFRARVQQ
ECCCCHHHCCCCCEEEEEEECCCCCCCHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LKGLAYREYENEAFRLMRDGLTASALAKRQQPHLSVYSDQIVWGRSPVRIDLAGGWTDTP
HHCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEECCEEEECCCCEEEEEECCCCCCC
PYCLNEGGNVVNIAIELNGQPPLQVYVKPCREYKIILRSIDLGAMEVVTTYGEVRDFMQV
CHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
GSPFSIPKAALVLAGFQPGFSTESYVSLEEQLKAFGSGMEITLLSAIPAGSGLGTSSILA
CCCCCCCHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
STVLGAISDFCGLNWDKNEICNRTLILEQLLTTGGGWQDQYGGVLRGVKLLQTHAGMDQS
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCC
PLVRWLPDYLFTGGEYQKCHLLYYTGITRTAKGILAEIVRSMFLNSTEHLSILGGMKGHA
CHHHHHHHHHHCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCH
LDLYEAIQRGNFDEMGRLVGKSWKLNQALDPGTNPEAVETIIRRIDDYCLGYKLPGAGGG
HHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEECCCCCCC
GYLYMVAKDPEAAIRIRSILTQNPPNSCARFVDMALSDKGLQISRS
CEEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA