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The map label for this gene is lacA [C]

Identifier: 150004109

GI number: 150004109

Start: 2032950

End: 2033288

Strand: Direct

Name: lacA [C]

Synonym: BVU_1544

Alternate gene names: 150004109

Gene position: 2032950-2033288 (Clockwise)

Preceding gene: 150004108

Following gene: 150004110

Centisome position: 39.37

GC content: 50.15

Gene sequence:

>339_bases
ATGGGGGGGGTAAACATCAAATGCCCTAAAAAGACCTTCATCGGAGAGGACGTTATTTTCGACACAAATTATCCCGAAGA
TATTGTCATTGAAGAGGGCGTGCGCCTGACTGTCGGCGTCCGGATTGTAACGCATTTCATGAACCCGAAGACAGGCAGTT
ATGACCGCGGTCAAGTGCATGTTGGCAAAGGAGCCTACATTGGCATGGGAACAATGGTTGTCAAGCCGGTCACAATCGGA
GAAGGGGCAATCGTAGGCGCCGGGGCAATAGTGACGAAAGATATACCGTCAAACGAAGTATGGGCAGGAAACCCCGCCCG
CTTTATCAGAAAACGATAA

Upstream 100 bases:

>100_bases
TAGATTTAATAATGAAACTGTCAAGAATTAAAAAACTTGTCTTCCTTCATTTACAGCATTTGCCAATGAAGTCAAGGGGT
TGGAGACCAACGCTTTGTAA

Downstream 100 bases:

>100_bases
AATTATGCCAAACGCAATATTTTTTTACAGAATACAGAGGTGGTTATACTTACACCACATTCCATTTTTACCTAAATTAA
TTCAACTATTAATTTTTCTG

Product: hypothetical protein

Products: CoA; aacetyl-beta-D-galactoside [C]

Alternate protein names: None

Number of amino acids: Translated: 112; Mature: 111

Protein sequence:

>112_residues
MGGVNIKCPKKTFIGEDVIFDTNYPEDIVIEEGVRLTVGVRIVTHFMNPKTGSYDRGQVHVGKGAYIGMGTMVVKPVTIG
EGAIVGAGAIVTKDIPSNEVWAGNPARFIRKR

Sequences:

>Translated_112_residues
MGGVNIKCPKKTFIGEDVIFDTNYPEDIVIEEGVRLTVGVRIVTHFMNPKTGSYDRGQVHVGKGAYIGMGTMVVKPVTIG
EGAIVGAGAIVTKDIPSNEVWAGNPARFIRKR
>Mature_111_residues
GGVNIKCPKKTFIGEDVIFDTNYPEDIVIEEGVRLTVGVRIVTHFMNPKTGSYDRGQVHVGKGAYIGMGTMVVKPVTIGE
GAIVGAGAIVTKDIPSNEVWAGNPARFIRKR

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.18 [C]

Molecular weight: Translated: 12059; Mature: 11928

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGVNIKCPKKTFIGEDVIFDTNYPEDIVIEEGVRLTVGVRIVTHFMNPKTGSYDRGQVH
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCCEEE
VGKGAYIGMGTMVVKPVTIGEGAIVGAGAIVTKDIPSNEVWAGNPARFIRKR
ECCCEEEECCEEEEEEEEECCCCEEECCEEEECCCCCCCEECCCHHHHEECC
>Mature Secondary Structure 
GGVNIKCPKKTFIGEDVIFDTNYPEDIVIEEGVRLTVGVRIVTHFMNPKTGSYDRGQVH
CCCCCCCCCCCCCCCEEEEECCCCCCEEEECCCEEEEEEEEEEEECCCCCCCCCCCEEE
VGKGAYIGMGTMVVKPVTIGEGAIVGAGAIVTKDIPSNEVWAGNPARFIRKR
ECCCEEEECCEEEEEEEEECCCCEEECCEEEECCCCCCCEECCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: MgSO4; Mn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.18 {acetyl-CoA}} 0.049 {acetyl-CoA}} 0.045 {acetyl-CoA}} 0.04 {acetyl-CoA}} 1500 {isopropyl} 1200 {isopropyl} 770 {isopropyl} 360 {isopropyl} [C]

Substrates: Acetyl-CoA; a beta-D-galactoside [C]

Specific reaction: Acetyl-CoA + a beta-D-galactoside = CoA + aacetyl-beta-D-galactoside [C]

General reaction: Acyl group transfer [C]

Inhibitor: 1, 10-Phenanthroline; Acetyl-CoA; Co2+; CoA; Cu2+; MgSO4; Mn2+; p-Chloromercuribenzoate; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA