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The map label for this gene is ftsI [H]

Identifier: 150003968

GI number: 150003968

Start: 1876359

End: 1878539

Strand: Reverse

Name: ftsI [H]

Synonym: BVU_1402

Alternate gene names: 150003968

Gene position: 1878539-1876359 (Counterclockwise)

Preceding gene: 150003969

Following gene: 150003967

Centisome position: 36.38

GC content: 44.52

Gene sequence:

>2181_bases
ATGATGCCCAACCAAAAAAACATAATGCTCCGCTTCTCCTTCATCATCCTGGTCATGGTGTTGATAGGCATTGCCATTAT
CTGCAAAGCCGGCGTCATCATGTTTGCCGAGCGTCAATACTGGAAAGACGTAGCCGACCGTTTTGTAAAAGAAAACGTCA
CCGTACGTCCTACCCGTGGCAACATCATCTCATCCGACGGCCAGCTGATGGCAAGCAGCCTTCCCGAATATAAGATTTAC
ATGGACTTCATGATAAATAAAAGGAAGGGCGAAACCGAAGAAGAGGAAAAGACACGGCTGAAGCTACAACATATCAAAGA
CTCAGTTCTTTATGCAAACCTTGACACAATCTGCAAAGGGTTACATGAAATATTTCCTGATAAAAGTGCCGCCTTTTTCA
AACAGCACATCAAAAACGGAAGAAAAAAAGAGAGCCGCAGTTGGTTGCTCTACCCCAAACGCATTTCTTATATACAATAT
AAAGAAGCAAAACGTCTGCCCGTATTTAACCTGAACAAATACAAAGGCGGATTCCATGAACAGGCATTCAATCAACGGAA
AAAGCCTTTTGGCTCACTGGCAATGCGTACATTGGGAGATATGTATCCAGATATAGAACAAGGTGCAAAGAACGGGCTGG
AACTTTCATACGATTCCATATTAAAAGGCAGAAACGGTATCACTCACCGTCAAAAGGTAATGAACAAATACCTGAACATT
GTAGATATTCCTCCTGTAGATGGCTGTGATATCATTACAACCATTGATGTAGGTATGCAAGACATTGCAGAAAAAGCATT
GGTGGATGAATTGAAAGAAATCAACGCTACTGTAGGCGTTGCCATTCTGATGGAAGTGCAGACGGGAGACATCAAAGCTA
TCGTCAACATGACCAAATGCAATGACGGCATTTACAGAGAAATACGCAATAACGCTATCTCAGACATGATGGAGCCAGGC
TCTACTTTCAAAACCGCATCCATACTGGTAGCGCTGGACGACGGAGTCATCACTCCGGAAACGGTGGTGGAAACCGGTAA
CGGGGTCTATATGATGCACGGCCGCTATATGAAAGATCATAACTGGCATCGTGGAGGCTACGGCACTATCAACACAACAA
AATCATTGATGGTGTCCTCAAACATCGGTGTATCACGGTTGATCGATGATCATTATCATGATAATCCGGAAAAGTTTGTA
CGCGGACTGCATCGAGTAGGCATTGCCACTCCGTTAGATCTCGATATTCCCGGTGCCGGCAAGCCGAACATCCGCATCCC
CAACAAAGACTTGAGCAATTGGTCACGTACTGCACTGGCATGGATGTCTATTGGCTATGAAACCCAAATTCCCCCCATCA
ATACACTGGCATTTTATAATGCTATAGCCAATAACGGAGTAATGGTCAAGCCCCGTTTTGTGAAATCAATAGTCAAAGAC
GGGCAGGTAGTGGAAGATATTGCTCCTGAAATACTCAACCCGGCCATCGCTTCCCCCAAGGCTATCAGCGAGATACAAAC
GATTTTGGAAAAAGTTGTCAGCGAAGGACTGGGAAAGAAAGCAGGATCCAAGCAATTCCATGTATCCGGGAAAACCGGTA
CTGCACAGGTTTCACAAGGAAAAGCCGGGTACACGAATGGCACACGCCGTTATTTGGTAAGTTTCTGTGGATATTTTCCT
TCAGAAGCGCCTAAATACAGTTGCATTGTAGCCATCCAGAAACCTGGACTCCCCGCCTCGGGTGGTCTGATGGCCGGCAG
CGTGTTCAGTAAAATTGCCGAACGCGTATTTGCCAAACATCTGGCACAAGATTTGAAAGAAGCAAAAGACTCAACTTCTA
TCCTTATTCCGGATGTGAAAAACGGGGATATAAGTGCGGCACATTATGTACTGAACCGGATAAATGTAAATTCATCCGGA
GTTTCGGAACAATCAACCGAAGGCAAACCGGTATGGGGAAATGTGACTAGTAATCCGGACAATGTATTATTCAACAAAAA
AGACATTAACAATAAACTTGTACCAAGTGTTATTGGTATGGGCGCAAAGGATGCTGTCTATCTGCTTGAAAGCATGGGAT
TGAAAGCCCGCATTACCGGCATCGGTAAAGTGAAGTCACAAAGTATCCCGGCCGGCAACACTTTGCGCAAAGGACAAACC
ATACAATTACGATTAAATTAA

Upstream 100 bases:

>100_bases
AAGAGCCGCCAGTCACGTATTGAAGAATATATTTCGACGGAAGACAGCCCCTTGCAAACGGCTACCAACCGTCCTTATTT
AATAAAGAAAGACTAAGCCC

Downstream 100 bases:

>100_bases
CAGTGTAACAGGAAGAATATGAAACTGGAAAAGATTATTAAAGGAATAACAGTCAATGAAATCATAGGTGATGCATCCCA
AGAAATTTCGGGAATAAACA

Product: penicillin-binding protein

Products: NA

Alternate protein names: Penicillin-binding protein 3; PBP-3; Peptidoglycan glycosyltransferase 3 [H]

Number of amino acids: Translated: 726; Mature: 726

Protein sequence:

>726_residues
MMPNQKNIMLRFSFIILVMVLIGIAIICKAGVIMFAERQYWKDVADRFVKENVTVRPTRGNIISSDGQLMASSLPEYKIY
MDFMINKRKGETEEEEKTRLKLQHIKDSVLYANLDTICKGLHEIFPDKSAAFFKQHIKNGRKKESRSWLLYPKRISYIQY
KEAKRLPVFNLNKYKGGFHEQAFNQRKKPFGSLAMRTLGDMYPDIEQGAKNGLELSYDSILKGRNGITHRQKVMNKYLNI
VDIPPVDGCDIITTIDVGMQDIAEKALVDELKEINATVGVAILMEVQTGDIKAIVNMTKCNDGIYREIRNNAISDMMEPG
STFKTASILVALDDGVITPETVVETGNGVYMMHGRYMKDHNWHRGGYGTINTTKSLMVSSNIGVSRLIDDHYHDNPEKFV
RGLHRVGIATPLDLDIPGAGKPNIRIPNKDLSNWSRTALAWMSIGYETQIPPINTLAFYNAIANNGVMVKPRFVKSIVKD
GQVVEDIAPEILNPAIASPKAISEIQTILEKVVSEGLGKKAGSKQFHVSGKTGTAQVSQGKAGYTNGTRRYLVSFCGYFP
SEAPKYSCIVAIQKPGLPASGGLMAGSVFSKIAERVFAKHLAQDLKEAKDSTSILIPDVKNGDISAAHYVLNRINVNSSG
VSEQSTEGKPVWGNVTSNPDNVLFNKKDINNKLVPSVIGMGAKDAVYLLESMGLKARITGIGKVKSQSIPAGNTLRKGQT
IQLRLN

Sequences:

>Translated_726_residues
MMPNQKNIMLRFSFIILVMVLIGIAIICKAGVIMFAERQYWKDVADRFVKENVTVRPTRGNIISSDGQLMASSLPEYKIY
MDFMINKRKGETEEEEKTRLKLQHIKDSVLYANLDTICKGLHEIFPDKSAAFFKQHIKNGRKKESRSWLLYPKRISYIQY
KEAKRLPVFNLNKYKGGFHEQAFNQRKKPFGSLAMRTLGDMYPDIEQGAKNGLELSYDSILKGRNGITHRQKVMNKYLNI
VDIPPVDGCDIITTIDVGMQDIAEKALVDELKEINATVGVAILMEVQTGDIKAIVNMTKCNDGIYREIRNNAISDMMEPG
STFKTASILVALDDGVITPETVVETGNGVYMMHGRYMKDHNWHRGGYGTINTTKSLMVSSNIGVSRLIDDHYHDNPEKFV
RGLHRVGIATPLDLDIPGAGKPNIRIPNKDLSNWSRTALAWMSIGYETQIPPINTLAFYNAIANNGVMVKPRFVKSIVKD
GQVVEDIAPEILNPAIASPKAISEIQTILEKVVSEGLGKKAGSKQFHVSGKTGTAQVSQGKAGYTNGTRRYLVSFCGYFP
SEAPKYSCIVAIQKPGLPASGGLMAGSVFSKIAERVFAKHLAQDLKEAKDSTSILIPDVKNGDISAAHYVLNRINVNSSG
VSEQSTEGKPVWGNVTSNPDNVLFNKKDINNKLVPSVIGMGAKDAVYLLESMGLKARITGIGKVKSQSIPAGNTLRKGQT
IQLRLN
>Mature_726_residues
MMPNQKNIMLRFSFIILVMVLIGIAIICKAGVIMFAERQYWKDVADRFVKENVTVRPTRGNIISSDGQLMASSLPEYKIY
MDFMINKRKGETEEEEKTRLKLQHIKDSVLYANLDTICKGLHEIFPDKSAAFFKQHIKNGRKKESRSWLLYPKRISYIQY
KEAKRLPVFNLNKYKGGFHEQAFNQRKKPFGSLAMRTLGDMYPDIEQGAKNGLELSYDSILKGRNGITHRQKVMNKYLNI
VDIPPVDGCDIITTIDVGMQDIAEKALVDELKEINATVGVAILMEVQTGDIKAIVNMTKCNDGIYREIRNNAISDMMEPG
STFKTASILVALDDGVITPETVVETGNGVYMMHGRYMKDHNWHRGGYGTINTTKSLMVSSNIGVSRLIDDHYHDNPEKFV
RGLHRVGIATPLDLDIPGAGKPNIRIPNKDLSNWSRTALAWMSIGYETQIPPINTLAFYNAIANNGVMVKPRFVKSIVKD
GQVVEDIAPEILNPAIASPKAISEIQTILEKVVSEGLGKKAGSKQFHVSGKTGTAQVSQGKAGYTNGTRRYLVSFCGYFP
SEAPKYSCIVAIQKPGLPASGGLMAGSVFSKIAERVFAKHLAQDLKEAKDSTSILIPDVKNGDISAAHYVLNRINVNSSG
VSEQSTEGKPVWGNVTSNPDNVLFNKKDINNKLVPSVIGMGAKDAVYLLESMGLKARITGIGKVKSQSIPAGNTLRKGQT
IQLRLN

Specific function: Cell wall formation. Essential for the formation of a septum of the murein sacculus. Synthesis of cross-linked peptidoglycan from the lipid intermediates [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell inner membrane (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=427, Percent_Identity=26.2295081967213, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1786854, Length=638, Percent_Identity=20.6896551724138, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: =2.4.1.129 [H]

Molecular weight: Translated: 80338; Mature: 80338

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPNQKNIMLRFSFIILVMVLIGIAIICKAGVIMFAERQYWKDVADRFVKENVTVRPTRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCEEECCCC
NIISSDGQLMASSLPEYKIYMDFMINKRKGETEEEEKTRLKLQHIKDSVLYANLDTICKG
CEECCCCHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEECHHHHHHH
LHEIFPDKSAAFFKQHIKNGRKKESRSWLLYPKRISYIQYKEAKRLPVFNLNKYKGGFHE
HHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHEEHHHCCCCCCEECHHCCCCHHH
QAFNQRKKPFGSLAMRTLGDMYPDIEQGAKNGLELSYDSILKGRNGITHRQKVMNKYLNI
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCEECHHHHHCCCCCCHHHHHHHHHHCCE
VDIPPVDGCDIITTIDVGMQDIAEKALVDELKEINATVGVAILMEVQTGDIKAIVNMTKC
EECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEHHHC
NDGIYREIRNNAISDMMEPGSTFKTASILVALDDGVITPETVVETGNGVYMMHGRYMKDH
CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHCCCCCEEEECCEEECCC
NWHRGGYGTINTTKSLMVSSNIGVSRLIDDHYHDNPEKFVRGLHRVGIATPLDLDIPGAG
CCCCCCCCCCCCCHHEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
KPNIRIPNKDLSNWSRTALAWMSIGYETQIPPINTLAFYNAIANNGVMVKPRFVKSIVKD
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHC
GQVVEDIAPEILNPAIASPKAISEIQTILEKVVSEGLGKKAGSKQFHVSGKTGTAQVSQG
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCC
KAGYTNGTRRYLVSFCGYFPSEAPKYSCIVAIQKPGLPASGGLMAGSVFSKIAERVFAKH
CCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LAQDLKEAKDSTSILIPDVKNGDISAAHYVLNRINVNSSGVSEQSTEGKPVWGNVTSNPD
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCC
NVLFNKKDINNKLVPSVIGMGAKDAVYLLESMGLKARITGIGKVKSQSIPAGNTLRKGQT
CEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCE
IQLRLN
EEEEEC
>Mature Secondary Structure
MMPNQKNIMLRFSFIILVMVLIGIAIICKAGVIMFAERQYWKDVADRFVKENVTVRPTRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHCCCEEECCCC
NIISSDGQLMASSLPEYKIYMDFMINKRKGETEEEEKTRLKLQHIKDSVLYANLDTICKG
CEECCCCHHHHHCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHEECHHHHHHH
LHEIFPDKSAAFFKQHIKNGRKKESRSWLLYPKRISYIQYKEAKRLPVFNLNKYKGGFHE
HHHHCCCCHHHHHHHHHHCCCCCCCCCEEEEHHHHHHEEHHHCCCCCCEECHHCCCCHHH
QAFNQRKKPFGSLAMRTLGDMYPDIEQGAKNGLELSYDSILKGRNGITHRQKVMNKYLNI
HHHHHHCCCHHHHHHHHHHHCCCCHHHHHCCCCEECHHHHHCCCCCCHHHHHHHHHHCCE
VDIPPVDGCDIITTIDVGMQDIAEKALVDELKEINATVGVAILMEVQTGDIKAIVNMTKC
EECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEHHHC
NDGIYREIRNNAISDMMEPGSTFKTASILVALDDGVITPETVVETGNGVYMMHGRYMKDH
CCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCCCCCCHHHHCCCCCEEEECCEEECCC
NWHRGGYGTINTTKSLMVSSNIGVSRLIDDHYHDNPEKFVRGLHRVGIATPLDLDIPGAG
CCCCCCCCCCCCCHHEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
KPNIRIPNKDLSNWSRTALAWMSIGYETQIPPINTLAFYNAIANNGVMVKPRFVKSIVKD
CCCEECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEECHHHHHHHHHC
GQVVEDIAPEILNPAIASPKAISEIQTILEKVVSEGLGKKAGSKQFHVSGKTGTAQVSQG
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEECCC
KAGYTNGTRRYLVSFCGYFPSEAPKYSCIVAIQKPGLPASGGLMAGSVFSKIAERVFAKH
CCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
LAQDLKEAKDSTSILIPDVKNGDISAAHYVLNRINVNSSGVSEQSTEGKPVWGNVTSNPD
HHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCC
NVLFNKKDINNKLVPSVIGMGAKDAVYLLESMGLKARITGIGKVKSQSIPAGNTLRKGQT
CEEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCE
IQLRLN
EEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]