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The map label for this gene is cah [H]

Identifier: 150003910

GI number: 150003910

Start: 1793125

End: 1794435

Strand: Direct

Name: cah [H]

Synonym: BVU_1343

Alternate gene names: 150003910

Gene position: 1793125-1794435 (Clockwise)

Preceding gene: 150003909

Following gene: 150003911

Centisome position: 34.73

GC content: 44.09

Gene sequence:

>1311_bases
ATGAAAAACAGATTTTTAAGCATGCTTATTGGGGCTGTCTTGTTCGTTCTTTCAGCAGCGGCCGAAAATTATCCTTATCG
GAGTGATGTGCTTTGGGTAACTGTACCCGATCATGCCGACTGGTTGTACAAGACAGGCGAGAAAGCGAAGATCGAGGTTC
AGTTCTATAAATATGGTATTCCGCAAGATGGTGTGGAGGTTTTATATGAGTTGGGAGGCGACATGATGCCTTCGGATACC
AAGGGAACTGTAAAACTGAAGAATGGAAAAGCGGTTATTTCTATGGGGACAATGAAAGAGCCCGGTTTTCGTGATTGTCG
TCTGACGGCTAAACTAGGAGGTAAAACTTATTCCCACCATATCAAAGTCGGCTTCTCTCCTGAGAAGCTTCAACCCTATA
CCCAGTTGCCTTCTGATTTTAATGAATTCTGGAATAAGACTAAGGCGGAAGCAGCCCGGTTCCCTCTGACTTATACCAAA
GAGTACGTAGAGAAATATTCTACGGACAAAATAGACTGTTACTTGATCAGACTTCAGCTGAATAAGCAGAGCCAGTGTAT
TTATGGTTATCTGTTCTATCCTAAGGCGGAAGGAAAGTATCCGGTAGTACTGTGTCCTCCGGGAGCAGGTATCAAGACGA
TCAAAGGGCCTATGAGGCATAAATATTATGCGGAAGAAGGCTGTATCCGCTTTGAGATAGAAATCCACGGCTTGAATCCG
GAGCTGGATGAGGACACTTTCGGCGAAATAAGCCGCGCTTTCAGTAGTCGGGAAAACGGTTATTTGGTAAACGGCTTGGA
TAGCCGTGAAAATTATTATATGAAACGGGTTTATCTGGCTTGTGTCCGCAGCATTGATTTGCTGACTTCATTACCTGAAT
GGGATGGTAAAAATGTTATTGTGCAAGGGGGGAGCCAAGGGGGAGCTTTGGCTTTGATTACGGCAGGACTTGACAAGCGT
GTTACGGCATGTGTGGCAAACCATCCCGCTTTAAGTGATATGGCAGGTTACAAAGCCGGTCGTGCCGGGGGATATCCTCA
TCTTTTTAAGAATACGGTAGATATGGATACACCTGCCAAGATGAAGACCCTTGCATATTATGATGTGGTGAATTTTGCCA
AACAGATTACTGTTCCTGTTTATATGACATGGGGATTCAATGACAATACTTGTCCTCCTACTACCAGTTACATTGTCTAT
AATGTACTGAACTGTCCGAAAGAGGCGTTGATTACTCCAGTCAACGAGCACTGGACTTCTGAAGACACAGAATACGGGCA
TTTGCTTTGGATAAAGAAACACTTGAAATAA

Upstream 100 bases:

>100_bases
GGGAATTGCTGGATAGTATGACAGGAGGGAGAGCTCGTGCCTTGCGTGCGGAGTTACGCAGATTTAATACTGATTTTTAG
AACCATTAAATAGAATTACA

Downstream 100 bases:

>100_bases
ATCGATGGAAATAGATGTTTTTAAGATTATAATTGCTATATTTGTTTAGCATAGTGTAGCAACTATCTGTATTTTGATGT
TGAACCCTTAAATCGCAAAC

Product: cephalosporin-C deacetylase

Products: NA

Alternate protein names: Acetyl xylan esterase [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKNRFLSMLIGAVLFVLSAAAENYPYRSDVLWVTVPDHADWLYKTGEKAKIEVQFYKYGIPQDGVEVLYELGGDMMPSDT
KGTVKLKNGKAVISMGTMKEPGFRDCRLTAKLGGKTYSHHIKVGFSPEKLQPYTQLPSDFNEFWNKTKAEAARFPLTYTK
EYVEKYSTDKIDCYLIRLQLNKQSQCIYGYLFYPKAEGKYPVVLCPPGAGIKTIKGPMRHKYYAEEGCIRFEIEIHGLNP
ELDEDTFGEISRAFSSRENGYLVNGLDSRENYYMKRVYLACVRSIDLLTSLPEWDGKNVIVQGGSQGGALALITAGLDKR
VTACVANHPALSDMAGYKAGRAGGYPHLFKNTVDMDTPAKMKTLAYYDVVNFAKQITVPVYMTWGFNDNTCPPTTSYIVY
NVLNCPKEALITPVNEHWTSEDTEYGHLLWIKKHLK

Sequences:

>Translated_436_residues
MKNRFLSMLIGAVLFVLSAAAENYPYRSDVLWVTVPDHADWLYKTGEKAKIEVQFYKYGIPQDGVEVLYELGGDMMPSDT
KGTVKLKNGKAVISMGTMKEPGFRDCRLTAKLGGKTYSHHIKVGFSPEKLQPYTQLPSDFNEFWNKTKAEAARFPLTYTK
EYVEKYSTDKIDCYLIRLQLNKQSQCIYGYLFYPKAEGKYPVVLCPPGAGIKTIKGPMRHKYYAEEGCIRFEIEIHGLNP
ELDEDTFGEISRAFSSRENGYLVNGLDSRENYYMKRVYLACVRSIDLLTSLPEWDGKNVIVQGGSQGGALALITAGLDKR
VTACVANHPALSDMAGYKAGRAGGYPHLFKNTVDMDTPAKMKTLAYYDVVNFAKQITVPVYMTWGFNDNTCPPTTSYIVY
NVLNCPKEALITPVNEHWTSEDTEYGHLLWIKKHLK
>Mature_436_residues
MKNRFLSMLIGAVLFVLSAAAENYPYRSDVLWVTVPDHADWLYKTGEKAKIEVQFYKYGIPQDGVEVLYELGGDMMPSDT
KGTVKLKNGKAVISMGTMKEPGFRDCRLTAKLGGKTYSHHIKVGFSPEKLQPYTQLPSDFNEFWNKTKAEAARFPLTYTK
EYVEKYSTDKIDCYLIRLQLNKQSQCIYGYLFYPKAEGKYPVVLCPPGAGIKTIKGPMRHKYYAEEGCIRFEIEIHGLNP
ELDEDTFGEISRAFSSRENGYLVNGLDSRENYYMKRVYLACVRSIDLLTSLPEWDGKNVIVQGGSQGGALALITAGLDKR
VTACVANHPALSDMAGYKAGRAGGYPHLFKNTVDMDTPAKMKTLAYYDVVNFAKQITVPVYMTWGFNDNTCPPTTSYIVY
NVLNCPKEALITPVNEHWTSEDTEYGHLLWIKKHLK

Specific function: Esterase that removed acetyl groups from a number of O- acetylated small substrates, such as acetylated xylose, short xylooligosaccharides and cephalosporin C. Has no activity towards polymeric acetylated xylan. Cannot cleave amide linkages [H]

COG id: COG3458

COG function: function code Q; Acetyl esterase (deacetylase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate esterase 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008391 [H]

Pfam domain/function: PF05448 AXE1 [H]

EC number: =3.1.1.41; =3.1.1.72 [H]

Molecular weight: Translated: 49235; Mature: 49235

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNRFLSMLIGAVLFVLSAAAENYPYRSDVLWVTVPDHADWLYKTGEKAKIEVQFYKYGI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCCEEEEEEEEEECC
PQDGVEVLYELGGDMMPSDTKGTVKLKNGKAVISMGTMKEPGFRDCRLTAKLGGKTYSHH
CCHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEEE
IKVGFSPEKLQPYTQLPSDFNEFWNKTKAEAARFPLTYTKEYVEKYSTDKIDCYLIRLQL
EEECCCHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEE
NKQSQCIYGYLFYPKAEGKYPVVLCPPGAGIKTIKGPMRHKYYAEEGCIRFEIEIHGLNP
CCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHCCCCHHHCEECCCCEEEEEEEEECCCC
ELDEDTFGEISRAFSSRENGYLVNGLDSRENYYMKRVYLACVRSIDLLTSLPEWDGKNVI
CCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VQGGSQGGALALITAGLDKRVTACVANHPALSDMAGYKAGRAGGYPHLFKNTVDMDTPAK
EECCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCH
MKTLAYYDVVNFAKQITVPVYMTWGFNDNTCPPTTSYIVYNVLNCPKEALITPVNEHWTS
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHHHCCC
EDTEYGHLLWIKKHLK
CCCCCCEEEEEEECCC
>Mature Secondary Structure
MKNRFLSMLIGAVLFVLSAAAENYPYRSDVLWVTVPDHADWLYKTGEKAKIEVQFYKYGI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHCCCCCEEEEEEEEEECC
PQDGVEVLYELGGDMMPSDTKGTVKLKNGKAVISMGTMKEPGFRDCRLTAKLGGKTYSHH
CCHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCEEEEE
IKVGFSPEKLQPYTQLPSDFNEFWNKTKAEAARFPLTYTKEYVEKYSTDKIDCYLIRLQL
EEECCCHHHCCCHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEE
NKQSQCIYGYLFYPKAEGKYPVVLCPPGAGIKTIKGPMRHKYYAEEGCIRFEIEIHGLNP
CCCCCEEEEEEEEECCCCCEEEEEECCCCCHHHCCCCHHHCEECCCCEEEEEEEEECCCC
ELDEDTFGEISRAFSSRENGYLVNGLDSRENYYMKRVYLACVRSIDLLTSLPEWDGKNVI
CCCCCHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VQGGSQGGALALITAGLDKRVTACVANHPALSDMAGYKAGRAGGYPHLFKNTVDMDTPAK
EECCCCCCEEEEEECCCCHHHHHHHCCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCCCH
MKTLAYYDVVNFAKQITVPVYMTWGFNDNTCPPTTSYIVYNVLNCPKEALITPVNEHWTS
HHHHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCHHHHCCCCHHHCCC
EDTEYGHLLWIKKHLK
CCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]