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The map label for this gene is trxA [H]

Identifier: 150003876

GI number: 150003876

Start: 1757793

End: 1758272

Strand: Direct

Name: trxA [H]

Synonym: BVU_1309

Alternate gene names: 150003876

Gene position: 1757793-1758272 (Clockwise)

Preceding gene: 150003875

Following gene: 150003877

Centisome position: 34.04

GC content: 41.25

Gene sequence:

>480_bases
ATGAATAAAACGATTTTATTTTTTTTAGCCCTTGTGCTGGCTGCCACAACAGCTTGCGGCAGAGGAAGCAGTAATAATAA
CCCTGTAAAAGAAGAAACTATGGCAACAGAAGGAAATGGAAAGGTCATACATTTGACTAAAGCTGAATTTTTGGCGAAAG
TATATAATTTCGAGAAAAACCCGGAAGAGTGGAAATATGAAGGTGACAAACCGGCTATTGTGGATTTCTATGCTGACTGG
TGTGGTCCTTGCAAAATGGTAGCTCCTATTTTGGACGAATTGGCAAAAGAATACGATGGCCAGATTGTGATTTATAAAGT
GGACACGGAGAAAGAACAGGAACTGGCAGGCGCGTTTGGTATACGGAGTATTCCGTCCATTCTGTTCATCCCCATGGAAG
GAAAGCCGGAGATGGCACAGGGGGCTATGCCCAAAGCGTCATTTAAAAAGGCTATTGATGAGTTTTTATTGAAAAAATAA

Upstream 100 bases:

>100_bases
CTTCTCCTGTCAACAGTTCCATTTGGGGGGCGGCAATGGGGGGATTGTTGCTCAGTTCATTTATGCCGGAGCATAAAAAG
ATAAAGAAGGAGGAATAAGT

Downstream 100 bases:

>100_bases
GTACTTTTGTGCAATAGCATCAAGAAGAAAGAGCAATATGGAAACTTTATGTAAAATAAGAGATCTCTATCGCGCTATTG
CAGAATTTGAAACACGGTTT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNKTILFFLALVLAATTACGRGSSNNNPVKEETMATEGNGKVIHLTKAEFLAKVYNFEKNPEEWKYEGDKPAIVDFYADW
CGPCKMVAPILDELAKEYDGQIVIYKVDTEKEQELAGAFGIRSIPSILFIPMEGKPEMAQGAMPKASFKKAIDEFLLKK

Sequences:

>Translated_159_residues
MNKTILFFLALVLAATTACGRGSSNNNPVKEETMATEGNGKVIHLTKAEFLAKVYNFEKNPEEWKYEGDKPAIVDFYADW
CGPCKMVAPILDELAKEYDGQIVIYKVDTEKEQELAGAFGIRSIPSILFIPMEGKPEMAQGAMPKASFKKAIDEFLLKK
>Mature_159_residues
MNKTILFFLALVLAATTACGRGSSNNNPVKEETMATEGNGKVIHLTKAEFLAKVYNFEKNPEEWKYEGDKPAIVDFYADW
CGPCKMVAPILDELAKEYDGQIVIYKVDTEKEQELAGAFGIRSIPSILFIPMEGKPEMAQGAMPKASFKKAIDEFLLKK

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788936, Length=88, Percent_Identity=45.4545454545455, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI87082331, Length=116, Percent_Identity=37.0689655172414, Blast_Score=84, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71980562, Length=111, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17507705, Length=86, Percent_Identity=29.0697674418605, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321648, Length=86, Percent_Identity=37.2093023255814, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323072, Length=84, Percent_Identity=36.9047619047619, Blast_Score=61, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24639826, Length=62, Percent_Identity=45.1612903225806, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17530795, Length=74, Percent_Identity=36.4864864864865, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573567, Length=73, Percent_Identity=36.986301369863, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17648013, Length=76, Percent_Identity=38.1578947368421, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24583090, Length=76, Percent_Identity=38.1578947368421, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24664269, Length=62, Percent_Identity=38.7096774193548, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 17688; Mature: 17688

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTILFFLALVLAATTACGRGSSNNNPVKEETMATEGNGKVIHLTKAEFLAKVYNFEKN
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCEEEEEHHHHHHHHHCCCCC
PEEWKYEGDKPAIVDFYADWCGPCKMVAPILDELAKEYDGQIVIYKVDTEKEQELAGAFG
CHHCCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHC
IRSIPSILFIPMEGKPEMAQGAMPKASFKKAIDEFLLKK
HHCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKTILFFLALVLAATTACGRGSSNNNPVKEETMATEGNGKVIHLTKAEFLAKVYNFEKN
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHEEECCCCCEEEEEHHHHHHHHHCCCCC
PEEWKYEGDKPAIVDFYADWCGPCKMVAPILDELAKEYDGQIVIYKVDTEKEQELAGAFG
CHHCCCCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHC
IRSIPSILFIPMEGKPEMAQGAMPKASFKKAIDEFLLKK
HHCCCCEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]