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The map label for this gene is pqqL [C]

Identifier: 150003837

GI number: 150003837

Start: 1708769

End: 1709989

Strand: Reverse

Name: pqqL [C]

Synonym: BVU_1269

Alternate gene names: 150003837

Gene position: 1709989-1708769 (Counterclockwise)

Preceding gene: 150003842

Following gene: 150003836

Centisome position: 33.12

GC content: 41.93

Gene sequence:

>1221_bases
ATGTCATACAATACTTTCACCTTGCCTAACGGACTGCGCATTATTCACGCTCCCAATCAGTCTAATGTAGCCTATTGCGG
CTTTGCCGTCGATGCCGGAACCCGTGATGAAAACGAACAGGAACAGGGAATGGCCCATTTCGTGGAACACCTTATCTTTA
AAGGAACACAAAAAAGACATGCATGGCACATCCTGAACCGCATGGAAAATGTAGGCGGAGATTTAAATGCATATACGAAT
AAGGAAGAAACAGTGATATACAGTGCTTTTCTGGTAGAACACTTCTCACGGGCAGCAGAACTGCTGGCAGATATTGTATT
TCACAGCACCTTCCCACAACATGAGATTGACAAAGAAGTGGAAGTGATTATTGATGAAATACAAAGTTATGAAGACAGTC
CGTCAGAACTGATTTTTGATGATTTCGAGGAATTGATTTTTCCCAATCATCCTTTGGGAAGGAATATTTTGGGCAAACCG
GACTTATTGCGTAGTTTCAAAAGTGAACACGCCTTGAATTTTACTTCCCGTTTTTACAAAGCTACCAATATGATCTTTTT
CATTCAAGGCAATATAGACTTTAAGAAAGTGATACGCACCATAGAGAAAGTGACAGCCGACATCCCTTTTTCCATTACCG
AACGCCAACGGACAGAACCTTTTCTCTATATTCCTAAGACATTGACACTGAATAAAGAAACACATCAAGCCCATGTAATG
ATAGGTAGCCGGGGATATAATGCATATAATGAAAAACGAACCGGACTTTACCTGCTGAACAATCTGCTGGGAGGACCCGG
TATGAACAGCCGGCTGAACGTTTCCTTGCGCGAACGCCGGGGGCTGGTCTATAACGTAGAAGCCAATCTGACCTCATACA
CAGACACAGGAGTGTTCTGCATCTATTTCGGAACAGATCCGGAAGATGCAGACCGTTGCATCGGACTAGTTCATAAAGAA
TTGAAAAAACTGCGTGACAGCAAACTAAGTTCCTCACAACTGAGTGCAGCAAAAAAACAGATCATCGGACAAATAGGAGT
TGCCGGAGACAATTTTGAGAACAATGCATTGGATATGGGAAAAACGTTCTTGCACTATGGTAAATTTGAAGGTCCGGAAG
AAGTATTCAAACGGATAGAAATGCTGACAGCAGAACATCTGTGGGATATCGCCAATGAAATGTTCGATGAAAATTATCTT
TCAACCTTGATATACCTATAA

Upstream 100 bases:

>100_bases
TGTTTTCTGTTAGTAAATACAAATATCTGCATTTTTTGAAGAACGGCAATAACTTTTGTTGTATTTTTGCCAACCGAAAC
TTATTTGAAGCAAAAAAACA

Downstream 100 bases:

>100_bases
AAACAGGAAATCACCCTAAATTTCAAACATTACATTTCTCACAAATAAAAATCTAATTGTATTTTTGTAAAAATACCTTT
AACTAATATCATTAATTTAT

Product: putative zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSYNTFTLPNGLRIIHAPNQSNVAYCGFAVDAGTRDENEQEQGMAHFVEHLIFKGTQKRHAWHILNRMENVGGDLNAYTN
KEETVIYSAFLVEHFSRAAELLADIVFHSTFPQHEIDKEVEVIIDEIQSYEDSPSELIFDDFEELIFPNHPLGRNILGKP
DLLRSFKSEHALNFTSRFYKATNMIFFIQGNIDFKKVIRTIEKVTADIPFSITERQRTEPFLYIPKTLTLNKETHQAHVM
IGSRGYNAYNEKRTGLYLLNNLLGGPGMNSRLNVSLRERRGLVYNVEANLTSYTDTGVFCIYFGTDPEDADRCIGLVHKE
LKKLRDSKLSSSQLSAAKKQIIGQIGVAGDNFENNALDMGKTFLHYGKFEGPEEVFKRIEMLTAEHLWDIANEMFDENYL
STLIYL

Sequences:

>Translated_406_residues
MSYNTFTLPNGLRIIHAPNQSNVAYCGFAVDAGTRDENEQEQGMAHFVEHLIFKGTQKRHAWHILNRMENVGGDLNAYTN
KEETVIYSAFLVEHFSRAAELLADIVFHSTFPQHEIDKEVEVIIDEIQSYEDSPSELIFDDFEELIFPNHPLGRNILGKP
DLLRSFKSEHALNFTSRFYKATNMIFFIQGNIDFKKVIRTIEKVTADIPFSITERQRTEPFLYIPKTLTLNKETHQAHVM
IGSRGYNAYNEKRTGLYLLNNLLGGPGMNSRLNVSLRERRGLVYNVEANLTSYTDTGVFCIYFGTDPEDADRCIGLVHKE
LKKLRDSKLSSSQLSAAKKQIIGQIGVAGDNFENNALDMGKTFLHYGKFEGPEEVFKRIEMLTAEHLWDIANEMFDENYL
STLIYL
>Mature_405_residues
SYNTFTLPNGLRIIHAPNQSNVAYCGFAVDAGTRDENEQEQGMAHFVEHLIFKGTQKRHAWHILNRMENVGGDLNAYTNK
EETVIYSAFLVEHFSRAAELLADIVFHSTFPQHEIDKEVEVIIDEIQSYEDSPSELIFDDFEELIFPNHPLGRNILGKPD
LLRSFKSEHALNFTSRFYKATNMIFFIQGNIDFKKVIRTIEKVTADIPFSITERQRTEPFLYIPKTLTLNKETHQAHVMI
GSRGYNAYNEKRTGLYLLNNLLGGPGMNSRLNVSLRERRGLVYNVEANLTSYTDTGVFCIYFGTDPEDADRCIGLVHKEL
KKLRDSKLSSSQLSAAKKQIIGQIGVAGDNFENNALDMGKTFLHYGKFEGPEEVFKRIEMLTAEHLWDIANEMFDENYLS
TLIYL

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=402, Percent_Identity=28.6069651741293, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI46593007, Length=407, Percent_Identity=25.7985257985258, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787770, Length=228, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71999683, Length=409, Percent_Identity=27.1393643031785, Blast_Score=161, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17553678, Length=400, Percent_Identity=24, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17510601, Length=421, Percent_Identity=21.6152019002375, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=405, Percent_Identity=29.8765432098765, Blast_Score=175, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6321813, Length=416, Percent_Identity=21.875, Blast_Score=93, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21357875, Length=391, Percent_Identity=27.8772378516624, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24646943, Length=391, Percent_Identity=27.8772378516624, Blast_Score=168, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46473; Mature: 46342

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYNTFTLPNGLRIIHAPNQSNVAYCGFAVDAGTRDENEQEQGMAHFVEHLIFKGTQKRH
CCCCCEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHH
AWHILNRMENVGGDLNAYTNKEETVIYSAFLVEHFSRAAELLADIVFHSTFPQHEIDKEV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EVIIDEIQSYEDSPSELIFDDFEELIFPNHPLGRNILGKPDLLRSFKSEHALNFTSRFYK
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATNMIFFIQGNIDFKKVIRTIEKVTADIPFSITERQRTEPFLYIPKTLTLNKETHQAHVM
HCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEECCCCCEEEEE
IGSRGYNAYNEKRTGLYLLNNLLGGPGMNSRLNVSLRERRGLVYNVEANLTSYTDTGVFC
EECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHCCEEEEEECCCEEECCCCEEE
IYFGTDPEDADRCIGLVHKELKKLRDSKLSSSQLSAAKKQIIGQIGVAGDNFENNALDMG
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KTFLHYGKFEGPEEVFKRIEMLTAEHLWDIANEMFDENYLSTLIYL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SYNTFTLPNGLRIIHAPNQSNVAYCGFAVDAGTRDENEQEQGMAHFVEHLIFKGTQKRH
CCCCEECCCCEEEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHH
AWHILNRMENVGGDLNAYTNKEETVIYSAFLVEHFSRAAELLADIVFHSTFPQHEIDKEV
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
EVIIDEIQSYEDSPSELIFDDFEELIFPNHPLGRNILGKPDLLRSFKSEHALNFTSRFYK
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
ATNMIFFIQGNIDFKKVIRTIEKVTADIPFSITERQRTEPFLYIPKTLTLNKETHQAHVM
HCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCEEEECCCCCEEEEE
IGSRGYNAYNEKRTGLYLLNNLLGGPGMNSRLNVSLRERRGLVYNVEANLTSYTDTGVFC
EECCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEEHHHCCEEEEEECCCEEECCCCEEE
IYFGTDPEDADRCIGLVHKELKKLRDSKLSSSQLSAAKKQIIGQIGVAGDNFENNALDMG
EEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
KTFLHYGKFEGPEEVFKRIEMLTAEHLWDIANEMFDENYLSTLIYL
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]