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The map label for this gene is coaD

Identifier: 150003804

GI number: 150003804

Start: 1660319

End: 1660774

Strand: Direct

Name: coaD

Synonym: BVU_1236

Alternate gene names: 150003804

Gene position: 1660319-1660774 (Clockwise)

Preceding gene: 150003803

Following gene: 150003805

Centisome position: 32.16

GC content: 44.3

Gene sequence:

>456_bases
ATGAGAAGAGCGATATTTCCGGGAACCTTTGATCCTTTTACCATCGGTCATTATTCGGTCGTGAAGAGAGCGTTGACTTT
TATGGACGAAGTGGTGATCGGCATCGGTATCAATGAGAATAAGAAAACTTGGTTTCCTACAGAGAAACGAGTGGAGATGA
TCGAGAAACTTTTTGCGGATGATCCCCGGGTAAAGGTCGATGCTTATGATTGTCTGACCATTGACTTTGCCCGAGCTAAG
GAGGCGCAGTTCATTGTTCGTGGTATCCGTACCGTACACGATTTTGAATATGAGGAAACTATAGCCGATATCAACCGGAA
ACTGGCCGGAATAGAAACGATTCTGTTGTTTACGGAGCCGGAACTAACCTCTATCAGCTCTACGATTGTAAGAGAATTGT
TGCAGTTTGGCAAAGATGTGACGCCATTCTTGCCTGAAGGAATGAAAATAGACTGA

Upstream 100 bases:

>100_bases
TGGAGTTCTACATGGGTAAGAACACGATGGAACGTCAGAATTTTATTATAGATAACCTTGTTGTAGAAGAAGATATTGCG
TGAGTGAATCACTAAAAAAT

Downstream 100 bases:

>100_bases
CCATGAAATATACTATGTATTTTGCAGGCTTGATTGCCTGCTTTTTTTCTATCGTAGCCGCACAGGCTCAGGAGAGTAAA
TTTCTGAATTCTCCGGCACG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRRAIFPGTFDPFTIGHYSVVKRALTFMDEVVIGIGINENKKTWFPTEKRVEMIEKLFADDPRVKVDAYDCLTIDFARAK
EAQFIVRGIRTVHDFEYEETIADINRKLAGIETILLFTEPELTSISSTIVRELLQFGKDVTPFLPEGMKID

Sequences:

>Translated_151_residues
MRRAIFPGTFDPFTIGHYSVVKRALTFMDEVVIGIGINENKKTWFPTEKRVEMIEKLFADDPRVKVDAYDCLTIDFARAK
EAQFIVRGIRTVHDFEYEETIADINRKLAGIETILLFTEPELTSISSTIVRELLQFGKDVTPFLPEGMKID
>Mature_151_residues
MRRAIFPGTFDPFTIGHYSVVKRALTFMDEVVIGIGINENKKTWFPTEKRVEMIEKLFADDPRVKVDAYDCLTIDFARAK
EAQFIVRGIRTVHDFEYEETIADINRKLAGIETILLFTEPELTSISSTIVRELLQFGKDVTPFLPEGMKID

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=149, Percent_Identity=40.2684563758389, Blast_Score=118, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_BACV8 (A6KZR2)

Other databases:

- EMBL:   CP000139
- RefSeq:   YP_001298548.1
- ProteinModelPortal:   A6KZR2
- SMR:   A6KZR2
- STRING:   A6KZR2
- GeneID:   5302202
- GenomeReviews:   CP000139_GR
- KEGG:   bvu:BVU_1236
- NMPDR:   fig|435590.6.peg.1165
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17349; Mature: 17349

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAIFPGTFDPFTIGHYSVVKRALTFMDEVVIGIGINENKKTWFPTEKRVEMIEKLFAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
DPRVKVDAYDCLTIDFARAKEAQFIVRGIRTVHDFEYEETIADINRKLAGIETILLFTEP
CCCEEEECEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEEEECCC
ELTSISSTIVRELLQFGKDVTPFLPEGMKID
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRAIFPGTFDPFTIGHYSVVKRALTFMDEVVIGIGINENKKTWFPTEKRVEMIEKLFAD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
DPRVKVDAYDCLTIDFARAKEAQFIVRGIRTVHDFEYEETIADINRKLAGIETILLFTEP
CCCEEEECEEEEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEEEEECCC
ELTSISSTIVRELLQFGKDVTPFLPEGMKID
CHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA