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The map label for this gene is cat [H]

Identifier: 150003770

GI number: 150003770

Start: 1620652

End: 1621308

Strand: Reverse

Name: cat [H]

Synonym: BVU_1202

Alternate gene names: 150003770

Gene position: 1621308-1620652 (Counterclockwise)

Preceding gene: 150003771

Following gene: 150003762

Centisome position: 31.4

GC content: 44.75

Gene sequence:

>657_bases
ATGAAACATATAATAGATATTGAAACCTGGGAACGCCGGGACAATTATAATTTTTTCCGCAACTTCCATAATTCATGGAT
ATCCATTACCAGTGAAGTGGATTGCACTGAAGCATTTCCAGCTGCAAAAGCCGCCAAGCGCTCTTTTTTCCTGTATTACC
TGTATGCTGTGCTACGTGCTGCCAATGAAGTGAAAGAATTCCGTTTCCGTACAGATAAAAACGGACAGGTGGTCTATCAC
GATCAGGTGGACATCATATCACCTATCGCTGTACCCGGCAAGACTTTCTACACAGTCCGCATCCCTTACCATGCAGATTT
TGAACGGTTTTATGCCGAAGCATATCACATCGTCCATAACATCCCCGAAGAGGGTGACCCGTATGGAGCCGAAAAAGTCA
TTACAGAACAGGGAGATTTTGATATTATCCAACTGAGTGCCACGCCTCAGCTTTATTTCACTTCACTCACCTATACACAA
ATGGCTCCCGACCATCCATTAGACTATCCGCTGATGAATGCCGGCAAAGTAGTGCCACGCGAAGGAAGACTGGTAATGCC
CATCGCTTTCACTGTAAACCATGCTTTTGTGGACGGAGCGCACATAGGACAACTCTTTCAGAAAATAGAGGAGATATTGA
AAGAGGTGGCTCAATAA

Upstream 100 bases:

>100_bases
TGAAGACAGTATGATGCTGAACATGGGGCAATGGCTCAGCATTCCGTTCATACTGCTGGGAGCGCACTTCATGTACCATT
CTTTTAAACCCGTAAAATAA

Downstream 100 bases:

>100_bases
ATAGAGGGGTCTCAAAAGGCATAAAAATCCCTATCGGACACGTATGTATGCATTTCCCTACATATGTTCACATATATCCA
TAAAAGAATAAATAACCAGA

Product: chloramphenicol acetyltransferase

Products: NA

Alternate protein names: CAT [H]

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKHIIDIETWERRDNYNFFRNFHNSWISITSEVDCTEAFPAAKAAKRSFFLYYLYAVLRAANEVKEFRFRTDKNGQVVYH
DQVDIISPIAVPGKTFYTVRIPYHADFERFYAEAYHIVHNIPEEGDPYGAEKVITEQGDFDIIQLSATPQLYFTSLTYTQ
MAPDHPLDYPLMNAGKVVPREGRLVMPIAFTVNHAFVDGAHIGQLFQKIEEILKEVAQ

Sequences:

>Translated_218_residues
MKHIIDIETWERRDNYNFFRNFHNSWISITSEVDCTEAFPAAKAAKRSFFLYYLYAVLRAANEVKEFRFRTDKNGQVVYH
DQVDIISPIAVPGKTFYTVRIPYHADFERFYAEAYHIVHNIPEEGDPYGAEKVITEQGDFDIIQLSATPQLYFTSLTYTQ
MAPDHPLDYPLMNAGKVVPREGRLVMPIAFTVNHAFVDGAHIGQLFQKIEEILKEVAQ
>Mature_218_residues
MKHIIDIETWERRDNYNFFRNFHNSWISITSEVDCTEAFPAAKAAKRSFFLYYLYAVLRAANEVKEFRFRTDKNGQVVYH
DQVDIISPIAVPGKTFYTVRIPYHADFERFYAEAYHIVHNIPEEGDPYGAEKVITEQGDFDIIQLSATPQLYFTSLTYTQ
MAPDHPLDYPLMNAGKVVPREGRLVMPIAFTVNHAFVDGAHIGQLFQKIEEILKEVAQ

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG4845

COG function: function code V; Chloramphenicol O-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloramphenicol acetyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023213
- InterPro:   IPR018372
- InterPro:   IPR001707
- ProDom:   PD002660 [H]

Pfam domain/function: PF00302 CAT [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 25262; Mature: 25262

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHIIDIETWERRDNYNFFRNFHNSWISITSEVDCTEAFPAAKAAKRSFFLYYLYAVLRA
CCCEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHH
ANEVKEFRFRTDKNGQVVYHDQVDIISPIAVPGKTFYTVRIPYHADFERFYAEAYHIVHN
HHHHHHHHHCCCCCCCEEEECCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHC
IPEEGDPYGAEKVITEQGDFDIIQLSATPQLYFTSLTYTQMAPDHPLDYPLMNAGKVVPR
CCCCCCCCCCHHEEECCCCEEEEEEECCCEEEEEEEEEHHCCCCCCCCCCCCCCCCCCCC
EGRLVMPIAFTVNHAFVDGAHIGQLFQKIEEILKEVAQ
CCCEEEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHIIDIETWERRDNYNFFRNFHNSWISITSEVDCTEAFPAAKAAKRSFFLYYLYAVLRA
CCCEECCCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHHHH
ANEVKEFRFRTDKNGQVVYHDQVDIISPIAVPGKTFYTVRIPYHADFERFYAEAYHIVHN
HHHHHHHHHCCCCCCCEEEECCCCEECCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHC
IPEEGDPYGAEKVITEQGDFDIIQLSATPQLYFTSLTYTQMAPDHPLDYPLMNAGKVVPR
CCCCCCCCCCHHEEECCCCEEEEEEECCCEEEEEEEEEHHCCCCCCCCCCCCCCCCCCCC
EGRLVMPIAFTVNHAFVDGAHIGQLFQKIEEILKEVAQ
CCCEEEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3900035 [H]