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The map label for this gene is evgS [H]

Identifier: 150003705

GI number: 150003705

Start: 1527345

End: 1531331

Strand: Direct

Name: evgS [H]

Synonym: BVU_1136

Alternate gene names: 150003705

Gene position: 1527345-1531331 (Clockwise)

Preceding gene: 150003704

Following gene: 150003707

Centisome position: 29.58

GC content: 41.46

Gene sequence:

>3987_bases
ATGAAAAGACTAGTCCTATTGCTATTGAACTTACTGATGCCGATGATTCTGTTTGCAGCGTCCAATGACCTCTGTTTCCG
TCATTTTTCTGTAGAAGACGGACTATCATCCAATTCGGTACGTGCTTTAATGCAAGATAAATACGGTTTCCTATGGATAG
GAACGGATGAAGGACTGAACCGCTATGACGGCACTACTGTAAAACTCTATAGGCTGAAAGATAGGGGAGCTAATGAAGCT
ATTTCATCTTTATACAGCACCCTCAACAAAATATGGATAGGTACAGACGAAGGCATATATATCTATGATTACGAAACAGA
AGATATAATGCCTTTTGTACTGGCCACCTCCAAAAATATCCATATTGAAACAAATACGAACCATATTGTCGAAGATAAAG
ACAAAAACCTATGGTTCACTACGGTAGGACAAGGAATATTCAAATACAACACTATCACCAACCACTTGGAGCAATACGAA
TTTAAAAACGAAAATGGTTTAATGGCAAGTGTACTGGTGGATAGTGAAAACCAAATATGGGCCATTACCAATTGGGGAAA
CTCAGGTCTTTTCAAACTGAATAAAGCAGAAAATAAATTCGAGACTTTTCCGCTCTCCTATGAAAGCGGAAAGCATGACT
CAAACGCATTGGTCATGTTGGAAGACTCGGAACATACACTGTGGTTAGGAACCTGGGAGTGTGGTTTGCAAAAAATCGAT
AAATACAGCGGAAAGGCCACTACTTATCTGCATCCCACAGACGGAAAAGGTGCCACCCATATTCATTCTATCATGGAATA
TGCCCCTCACCAGCTACTCATAGGCTCGGATGACGGGCTTCTGTTATTCAATACCATTACAGAGGAATATCAATTGTTTA
CAGAAGATGAAACAAACCCACATTCATTGTCCAACTGTTTTGTTTATCCTATTATAAAAGATCATGAAGGTGGAATATGG
ATCGGAACTTACTATGGAGGAGTAAATTATATTTCACCCAATACTGGACAATTCGAAAGTTTTGTCCACTCACGTTTCTC
CAATTCTGTTAACGGAACAGTCATCGGACGGTTCTGCGAAGACTCTAACGGAGATGTGTGGATCGCTTCGGATGACGGAG
GGTTAAACCGCTTTTCTCCCAAAAATAGAAAATTTTCCCATTATTTGCCCTTGGAGGGAAAAAACAGTCTGTCCTATCAC
AATGTACATGCACTTTGTATGGACGATGATAATTTATGGATCGGTACTTATACTGGAGGGGTAAACGTATTAAATCTGCA
AACGGGAACTTTTAAAACATATTCTGCCTATCAGGATAATCCCGCCTCACTGGACGGAACCAGTTCTTATGCCATATTCA
AAGACAGAAAAGAGAGAATATGGGTCACCTCCATGTCCGGAGTAAATCTATATAACCGGGAAAAAGATAATTTCACCCGA
ATTAAAGACTTGGACGCACTGACCATTGACATTGACCAGGATACCAAAGGAAATCTCTGGTTCTCCACCCAAGGCAAGGG
ATTATTTAAATACCATCCAGAAAAACAGATATGGAAGAACTATATACATGACCATAAAAATCCGAACTCACTGGCAAACA
ACCAAGTGAACTGCGTACTGATTGACACAAACGGAGAGATGTGGGTGGGAACCATGAACGGGCTCTGCAAATACAATGCG
GAAGAAGATGCATTCGAAACTTTACCTCTTGAAATTCCCAGTCACAATATATGCAGCATCATCGAAGACCAACGCATATT
GTGGCTCACCACCACCAAAGGGCTAGTGCGCTACACCCCTGGAGAAGGTTGCCGAGTATTTACTAAAAGCGACGGACTGC
AAAGTGAACAATTCCTACCTAATGCTGCCTTAAAAGCATCGGATGGAAAAATCTATATCGGCTCAGTAAACGGATTCAAT
GCTTTCTACCCCCATCAGATTAAGACAAATGTGATGCTTCCTCCAGTAATCATTACAGAACTGGAAATAGATAATAAGGA
AATCCAAACTGGAAACAAACTGCTTCCAAAATCTCTCAACCAGTTGGAAGAACTGGAGCTATCCTATAAAGAAAATGCAT
TCAGCTTGCTTTATGCCTCTTTAAGCTATTGCACCCCCAATAAAAACAAATACGCCTATAAACTGGAAGGATTTGACAAA
GACTGGAACTATGTAGGCTCCCAGAATAAGGCCACTTACACCAATTTGCCCGCAGGAACCTATCTTTTCAAAGTAAAGGC
GACCAATAATGACGGAATATGGAATGAAAAAGGAACCAGTCTGAAAATCACCATCCACCCTCCTTTCTATTGGTCCACCG
CTTCCAAACTGCTCTATTTTGTATTGGTTTGCATAGCTTTCGGATTCGTCATCCGCTTCATCATCAAACGGACAGAGAAG
AAACATACGGCTGAAATAAACAAACTGAACGCCAACAAGGAAAAAGAAGTACACGAAGCCAAAATCAAGTTCTTCACCAT
GATAGCCCACGAAATACGCACACCGGTATCCCTTATCATAGGACCTTTGGAGAAAATAATGAAATCTCCCGTGTCCCTTC
CTTCTACAGTACGCGACGATCTGAATATTATTGACCGTAACAGCCAGCGTCTGCTGTTCCTGGTAAACCAATTGCTGGAT
TTCCGGAAGGTGGAACAGGAAGGAATGAAAATGAAGTTTGCTTCCCAAAATATCCACCAACTGCTCAAAGCGGTTTGTGA
ACGTTTCGAACCTTTCATCGCCCAACATGGAGCACGGCTTACTGTAAAATATCCTGAAGCAGATTTCACGGCTATAGTAG
ACAGTGAGGCGGTAACCAAACTAGTCAGCAATCTGTTGACCAATGCCAGTAAATACACAAAAGATGAAGTTACTCTTACC
TGTATCGTACAGCCGGAACAACATACTTTTATAATCCGAGTGACAGATAACGGCATAGGGATCAGCAAAGAAGAACAAAA
GAAGATATTCCATCCGTTCTATCAGGCTATGGATAACAAGCCGGGAACAGGTATCGGCCTCAGCATTGTCAAAAGTATCG
TAGAATCACACAATGGCTGCATTGAAGTGGAATCCGAAGTGAACAAAGGGTCATCTTTTATCGTAACACTGCCTGTAGAA
CAAGTACAAGTCCTGCCACAGGATACGGGCACATCACTATTGAACAACCCAACCATTCCCGAAGGAATCTTGCAAGAGGA
CCTCTCCGGTTCTCCTATCAAACATAAACCAACCATGCTGATTGTGGATGATAATGAGGAAATGTTGAATTTCCTTTCGA
GTAGTCTGACTGATAAATACAGCATACTTACCGCAGAAGACGGTATAGAAGCACTGAATAAACTGAAAGAAAACGAAGTG
ACACTCATTGTAAGCGACTGGATGATGCCACGCATGGACGGAGTGGAATTCTGCAAAGCAATAAGGACTAACCAGGCTAC
CAGTCATATACCCTTCATCCTGCTAACGGCCAAGACAGATACCAACTCCAAGATAGAAGGTATGGATTGTGGTGCAGATG
CCTACATAGAGAAACCTTTCTCCATGCAATACTTGGAAGCATGTATCAAGAATCTAGTAGACTTGCGTAATCTACTGCGT
CAGAAATTCTCGAAGATGCCGTTGGTTCCACTGAACAGCATTGCCAATAATTCTATGGACGACAAGTTCCTTACCCGTAT
GAATGAAATCATAGAAGAGAATTTCTCCAATCCGGAATTATCCGTAGATTTCCTGGCCGAAAAATTGTGTATCAGCCGTT
CGGGTCTGTTTGCCAAAATTAAAACATTGGCCAATATCACCCCTAATGAACTGATTCAAGTGGTACGTTTGAAAAAAGCA
GCGATCTTGCTGGCAGAAAACAAATATCGCATCAATGAAATCTGTTATATGGTAGGATTCAATAATCCGTCTTATTTCTC
CAAATGTTTCCAAAAACAGTTCGGCATGAAACCGGGGGAATTTGTAAACGGGAAAAGAGAAGAATAA

Upstream 100 bases:

>100_bases
AGATTCATCTGGAATCCTCACTTTTTCTTCGAATTTTCTCTTTTCTTTCTCAGAAAAATAGTAATCTTGCATAAGATTTA
GAAAATAAGAAGAAAATACT

Downstream 100 bases:

>100_bases
AAACTAATCAAAAATCATTTCCTAAAAATAAAAAATCCGGTTTCCCCTTTTCAGAGAAACCGGATCCATGATGAACGAGT
GGTTTTATTTCAATCAATAA

Product: two-component system sensor histidine kinase/response regulator, hybrid

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1328; Mature: 1328

Protein sequence:

>1328_residues
MKRLVLLLLNLLMPMILFAASNDLCFRHFSVEDGLSSNSVRALMQDKYGFLWIGTDEGLNRYDGTTVKLYRLKDRGANEA
ISSLYSTLNKIWIGTDEGIYIYDYETEDIMPFVLATSKNIHIETNTNHIVEDKDKNLWFTTVGQGIFKYNTITNHLEQYE
FKNENGLMASVLVDSENQIWAITNWGNSGLFKLNKAENKFETFPLSYESGKHDSNALVMLEDSEHTLWLGTWECGLQKID
KYSGKATTYLHPTDGKGATHIHSIMEYAPHQLLIGSDDGLLLFNTITEEYQLFTEDETNPHSLSNCFVYPIIKDHEGGIW
IGTYYGGVNYISPNTGQFESFVHSRFSNSVNGTVIGRFCEDSNGDVWIASDDGGLNRFSPKNRKFSHYLPLEGKNSLSYH
NVHALCMDDDNLWIGTYTGGVNVLNLQTGTFKTYSAYQDNPASLDGTSSYAIFKDRKERIWVTSMSGVNLYNREKDNFTR
IKDLDALTIDIDQDTKGNLWFSTQGKGLFKYHPEKQIWKNYIHDHKNPNSLANNQVNCVLIDTNGEMWVGTMNGLCKYNA
EEDAFETLPLEIPSHNICSIIEDQRILWLTTTKGLVRYTPGEGCRVFTKSDGLQSEQFLPNAALKASDGKIYIGSVNGFN
AFYPHQIKTNVMLPPVIITELEIDNKEIQTGNKLLPKSLNQLEELELSYKENAFSLLYASLSYCTPNKNKYAYKLEGFDK
DWNYVGSQNKATYTNLPAGTYLFKVKATNNDGIWNEKGTSLKITIHPPFYWSTASKLLYFVLVCIAFGFVIRFIIKRTEK
KHTAEINKLNANKEKEVHEAKIKFFTMIAHEIRTPVSLIIGPLEKIMKSPVSLPSTVRDDLNIIDRNSQRLLFLVNQLLD
FRKVEQEGMKMKFASQNIHQLLKAVCERFEPFIAQHGARLTVKYPEADFTAIVDSEAVTKLVSNLLTNASKYTKDEVTLT
CIVQPEQHTFIIRVTDNGIGISKEEQKKIFHPFYQAMDNKPGTGIGLSIVKSIVESHNGCIEVESEVNKGSSFIVTLPVE
QVQVLPQDTGTSLLNNPTIPEGILQEDLSGSPIKHKPTMLIVDDNEEMLNFLSSSLTDKYSILTAEDGIEALNKLKENEV
TLIVSDWMMPRMDGVEFCKAIRTNQATSHIPFILLTAKTDTNSKIEGMDCGADAYIEKPFSMQYLEACIKNLVDLRNLLR
QKFSKMPLVPLNSIANNSMDDKFLTRMNEIIEENFSNPELSVDFLAEKLCISRSGLFAKIKTLANITPNELIQVVRLKKA
AILLAENKYRINEICYMVGFNNPSYFSKCFQKQFGMKPGEFVNGKREE

Sequences:

>Translated_1328_residues
MKRLVLLLLNLLMPMILFAASNDLCFRHFSVEDGLSSNSVRALMQDKYGFLWIGTDEGLNRYDGTTVKLYRLKDRGANEA
ISSLYSTLNKIWIGTDEGIYIYDYETEDIMPFVLATSKNIHIETNTNHIVEDKDKNLWFTTVGQGIFKYNTITNHLEQYE
FKNENGLMASVLVDSENQIWAITNWGNSGLFKLNKAENKFETFPLSYESGKHDSNALVMLEDSEHTLWLGTWECGLQKID
KYSGKATTYLHPTDGKGATHIHSIMEYAPHQLLIGSDDGLLLFNTITEEYQLFTEDETNPHSLSNCFVYPIIKDHEGGIW
IGTYYGGVNYISPNTGQFESFVHSRFSNSVNGTVIGRFCEDSNGDVWIASDDGGLNRFSPKNRKFSHYLPLEGKNSLSYH
NVHALCMDDDNLWIGTYTGGVNVLNLQTGTFKTYSAYQDNPASLDGTSSYAIFKDRKERIWVTSMSGVNLYNREKDNFTR
IKDLDALTIDIDQDTKGNLWFSTQGKGLFKYHPEKQIWKNYIHDHKNPNSLANNQVNCVLIDTNGEMWVGTMNGLCKYNA
EEDAFETLPLEIPSHNICSIIEDQRILWLTTTKGLVRYTPGEGCRVFTKSDGLQSEQFLPNAALKASDGKIYIGSVNGFN
AFYPHQIKTNVMLPPVIITELEIDNKEIQTGNKLLPKSLNQLEELELSYKENAFSLLYASLSYCTPNKNKYAYKLEGFDK
DWNYVGSQNKATYTNLPAGTYLFKVKATNNDGIWNEKGTSLKITIHPPFYWSTASKLLYFVLVCIAFGFVIRFIIKRTEK
KHTAEINKLNANKEKEVHEAKIKFFTMIAHEIRTPVSLIIGPLEKIMKSPVSLPSTVRDDLNIIDRNSQRLLFLVNQLLD
FRKVEQEGMKMKFASQNIHQLLKAVCERFEPFIAQHGARLTVKYPEADFTAIVDSEAVTKLVSNLLTNASKYTKDEVTLT
CIVQPEQHTFIIRVTDNGIGISKEEQKKIFHPFYQAMDNKPGTGIGLSIVKSIVESHNGCIEVESEVNKGSSFIVTLPVE
QVQVLPQDTGTSLLNNPTIPEGILQEDLSGSPIKHKPTMLIVDDNEEMLNFLSSSLTDKYSILTAEDGIEALNKLKENEV
TLIVSDWMMPRMDGVEFCKAIRTNQATSHIPFILLTAKTDTNSKIEGMDCGADAYIEKPFSMQYLEACIKNLVDLRNLLR
QKFSKMPLVPLNSIANNSMDDKFLTRMNEIIEENFSNPELSVDFLAEKLCISRSGLFAKIKTLANITPNELIQVVRLKKA
AILLAENKYRINEICYMVGFNNPSYFSKCFQKQFGMKPGEFVNGKREE
>Mature_1328_residues
MKRLVLLLLNLLMPMILFAASNDLCFRHFSVEDGLSSNSVRALMQDKYGFLWIGTDEGLNRYDGTTVKLYRLKDRGANEA
ISSLYSTLNKIWIGTDEGIYIYDYETEDIMPFVLATSKNIHIETNTNHIVEDKDKNLWFTTVGQGIFKYNTITNHLEQYE
FKNENGLMASVLVDSENQIWAITNWGNSGLFKLNKAENKFETFPLSYESGKHDSNALVMLEDSEHTLWLGTWECGLQKID
KYSGKATTYLHPTDGKGATHIHSIMEYAPHQLLIGSDDGLLLFNTITEEYQLFTEDETNPHSLSNCFVYPIIKDHEGGIW
IGTYYGGVNYISPNTGQFESFVHSRFSNSVNGTVIGRFCEDSNGDVWIASDDGGLNRFSPKNRKFSHYLPLEGKNSLSYH
NVHALCMDDDNLWIGTYTGGVNVLNLQTGTFKTYSAYQDNPASLDGTSSYAIFKDRKERIWVTSMSGVNLYNREKDNFTR
IKDLDALTIDIDQDTKGNLWFSTQGKGLFKYHPEKQIWKNYIHDHKNPNSLANNQVNCVLIDTNGEMWVGTMNGLCKYNA
EEDAFETLPLEIPSHNICSIIEDQRILWLTTTKGLVRYTPGEGCRVFTKSDGLQSEQFLPNAALKASDGKIYIGSVNGFN
AFYPHQIKTNVMLPPVIITELEIDNKEIQTGNKLLPKSLNQLEELELSYKENAFSLLYASLSYCTPNKNKYAYKLEGFDK
DWNYVGSQNKATYTNLPAGTYLFKVKATNNDGIWNEKGTSLKITIHPPFYWSTASKLLYFVLVCIAFGFVIRFIIKRTEK
KHTAEINKLNANKEKEVHEAKIKFFTMIAHEIRTPVSLIIGPLEKIMKSPVSLPSTVRDDLNIIDRNSQRLLFLVNQLLD
FRKVEQEGMKMKFASQNIHQLLKAVCERFEPFIAQHGARLTVKYPEADFTAIVDSEAVTKLVSNLLTNASKYTKDEVTLT
CIVQPEQHTFIIRVTDNGIGISKEEQKKIFHPFYQAMDNKPGTGIGLSIVKSIVESHNGCIEVESEVNKGSSFIVTLPVE
QVQVLPQDTGTSLLNNPTIPEGILQEDLSGSPIKHKPTMLIVDDNEEMLNFLSSSLTDKYSILTAEDGIEALNKLKENEV
TLIVSDWMMPRMDGVEFCKAIRTNQATSHIPFILLTAKTDTNSKIEGMDCGADAYIEKPFSMQYLEACIKNLVDLRNLLR
QKFSKMPLVPLNSIANNSMDDKFLTRMNEIIEENFSNPELSVDFLAEKLCISRSGLFAKIKTLANITPNELIQVVRLKKA
AILLAENKYRINEICYMVGFNNPSYFSKCFQKQFGMKPGEFVNGKREE

Specific function: Member of the two-component regulatory system evgS/evgA. Phosphorylates evgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG3292

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=438, Percent_Identity=28.5388127853881, Blast_Score=156, Evalue=8e-39,
Organism=Escherichia coli, GI145693157, Length=338, Percent_Identity=28.1065088757396, Blast_Score=110, Evalue=6e-25,
Organism=Escherichia coli, GI48994928, Length=393, Percent_Identity=27.2264631043257, Blast_Score=106, Evalue=1e-23,
Organism=Escherichia coli, GI87081816, Length=352, Percent_Identity=25, Blast_Score=102, Evalue=2e-22,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=28.5087719298246, Blast_Score=90, Evalue=9e-19,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=28.6919831223629, Blast_Score=90, Evalue=1e-18,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=27.3542600896861, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=27.2357723577236, Blast_Score=87, Evalue=9e-18,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=24.8, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI1788191, Length=109, Percent_Identity=37.6146788990826, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=271, Percent_Identity=26.9372693726937, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786599, Length=115, Percent_Identity=36.5217391304348, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI1789808, Length=230, Percent_Identity=26.5217391304348, Blast_Score=77, Evalue=9e-15,
Organism=Escherichia coli, GI1786783, Length=222, Percent_Identity=27.9279279279279, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI87082012, Length=124, Percent_Identity=32.258064516129, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789809, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=26.9387755102041, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=28.099173553719, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 150507; Mature: 150507

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2 ; PS50109 HIS_KIN ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLVLLLLNLLMPMILFAASNDLCFRHFSVEDGLSSNSVRALMQDKYGFLWIGTDEGLN
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCC
RYDGTTVKLYRLKDRGANEAISSLYSTLNKIWIGTDEGIYIYDYETEDIMPFVLATSKNI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCEEEEECCCEE
HIETNTNHIVEDKDKNLWFTTVGQGIFKYNTITNHLEQYEFKNENGLMASVLVDSENQIW
EEEECCCCEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCEEEEEEEECCCCEE
AITNWGNSGLFKLNKAENKFETFPLSYESGKHDSNALVMLEDSEHTLWLGTWECGLQKID
EEEECCCCCEEEEECCCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHH
KYSGKATTYLHPTDGKGATHIHSIMEYAPHQLLIGSDDGLLLFNTITEEYQLFTEDETNP
HCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEEEECCCCCC
HSLSNCFVYPIIKDHEGGIWIGTYYGGVNYISPNTGQFESFVHSRFSNSVNGTVIGRFCE
CCCCCEEEEEEEEECCCCEEEEEEECCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEC
DSNGDVWIASDDGGLNRFSPKNRKFSHYLPLEGKNSLSYHNVHALCMDDDNLWIGTYTGG
CCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEEECCCEEEEEECCC
VNVLNLQTGTFKTYSAYQDNPASLDGTSSYAIFKDRKERIWVTSMSGVNLYNREKDNFTR
EEEEEEECCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCE
IKDLDALTIDIDQDTKGNLWFSTQGKGLFKYHPEKQIWKNYIHDHKNPNSLANNQVNCVL
EECCCEEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHCCCCCCHHCCCCEEEEE
IDTNGEMWVGTMNGLCKYNAEEDAFETLPLEIPSHNICSIIEDQRILWLTTTKGLVRYTP
EECCCCEEEEECCCEEECCCCCCHHHCCCEECCCCCHHHHCCCCEEEEEEECCCEEEECC
GEGCRVFTKSDGLQSEQFLPNAALKASDGKIYIGSVNGFNAFYPHQIKTNVMLPPVIITE
CCCCEEEECCCCCCCHHCCCCCCEECCCCEEEEEECCCCCCCCCCEEECCEECCCEEEEE
LEIDNKEIQTGNKLLPKSLNQLEELELSYKENAFSLLYASLSYCTPNKNKYAYKLEGFDK
EEECCCHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC
DWNYVGSQNKATYTNLPAGTYLFKVKATNNDGIWNEKGTSLKITIHPPFYWSTASKLLYF
CCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
VLVCIAFGFVIRFIIKRTEKKHTAEINKLNANKEKEVHEAKIKFFTMIAHEIRTPVSLII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GPLEKIMKSPVSLPSTVRDDLNIIDRNSQRLLFLVNQLLDFRKVEQEGMKMKFASQNIHQ
HHHHHHHHCCCCCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHH
LLKAVCERFEPFIAQHGARLTVKYPEADFTAIVDSEAVTKLVSNLLTNASKYTKDEVTLT
HHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHCCHHCCCCCEEEE
CIVQPEQHTFIIRVTDNGIGISKEEQKKIFHPFYQAMDNKPGTGIGLSIVKSIVESHNGC
EEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
IEVESEVNKGSSFIVTLPVEQVQVLPQDTGTSLLNNPTIPEGILQEDLSGSPIKHKPTML
EEEECCCCCCCEEEEEECHHHHEECCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCCEEE
IVDDNEEMLNFLSSSLTDKYSILTAEDGIEALNKLKENEVTLIVSDWMMPRMDGVEFCKA
EECCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
IRTNQATSHIPFILLTAKTDTNSKIEGMDCGADAYIEKPFSMQYLEACIKNLVDLRNLLR
HHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
QKFSKMPLVPLNSIANNSMDDKFLTRMNEIIEENFSNPELSVDFLAEKLCISRSGLFAKI
HHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
KTLANITPNELIQVVRLKKAAILLAENKYRINEICYMVGFNNPSYFSKCFQKQFGMKPGE
HHHHCCCHHHHHHHHHHHHEEEEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCH
FVNGKREE
HCCCCCCC
>Mature Secondary Structure
MKRLVLLLLNLLMPMILFAASNDLCFRHFSVEDGLSSNSVRALMQDKYGFLWIGTDEGLN
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCC
RYDGTTVKLYRLKDRGANEAISSLYSTLNKIWIGTDEGIYIYDYETEDIMPFVLATSKNI
CCCCCEEEEEEECCCCHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCEEEEECCCEE
HIETNTNHIVEDKDKNLWFTTVGQGIFKYNTITNHLEQYEFKNENGLMASVLVDSENQIW
EEEECCCCEEECCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCEEEEEEEECCCCEE
AITNWGNSGLFKLNKAENKFETFPLSYESGKHDSNALVMLEDSEHTLWLGTWECGLQKID
EEEECCCCCEEEEECCCCCCEECCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHH
KYSGKATTYLHPTDGKGATHIHSIMEYAPHQLLIGSDDGLLLFNTITEEYQLFTEDETNP
HCCCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCEEEECCCCCC
HSLSNCFVYPIIKDHEGGIWIGTYYGGVNYISPNTGQFESFVHSRFSNSVNGTVIGRFCE
CCCCCEEEEEEEEECCCCEEEEEEECCEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEC
DSNGDVWIASDDGGLNRFSPKNRKFSHYLPLEGKNSLSYHNVHALCMDDDNLWIGTYTGG
CCCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEEECCCEEEEEECCC
VNVLNLQTGTFKTYSAYQDNPASLDGTSSYAIFKDRKERIWVTSMSGVNLYNREKDNFTR
EEEEEEECCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCCCCCCCE
IKDLDALTIDIDQDTKGNLWFSTQGKGLFKYHPEKQIWKNYIHDHKNPNSLANNQVNCVL
EECCCEEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHCCCCCCHHCCCCEEEEE
IDTNGEMWVGTMNGLCKYNAEEDAFETLPLEIPSHNICSIIEDQRILWLTTTKGLVRYTP
EECCCCEEEEECCCEEECCCCCCHHHCCCEECCCCCHHHHCCCCEEEEEEECCCEEEECC
GEGCRVFTKSDGLQSEQFLPNAALKASDGKIYIGSVNGFNAFYPHQIKTNVMLPPVIITE
CCCCEEEECCCCCCCHHCCCCCCEECCCCEEEEEECCCCCCCCCCEEECCEECCCEEEEE
LEIDNKEIQTGNKLLPKSLNQLEELELSYKENAFSLLYASLSYCTPNKNKYAYKLEGFDK
EEECCCHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEEECCCCC
DWNYVGSQNKATYTNLPAGTYLFKVKATNNDGIWNEKGTSLKITIHPPFYWSTASKLLYF
CCCCCCCCCCCEEECCCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
VLVCIAFGFVIRFIIKRTEKKHTAEINKLNANKEKEVHEAKIKFFTMIAHEIRTPVSLII
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
GPLEKIMKSPVSLPSTVRDDLNIIDRNSQRLLFLVNQLLDFRKVEQEGMKMKFASQNIHQ
HHHHHHHHCCCCCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHH
LLKAVCERFEPFIAQHGARLTVKYPEADFTAIVDSEAVTKLVSNLLTNASKYTKDEVTLT
HHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECHHHHHHHHHHHHHCCHHCCCCCEEEE
CIVQPEQHTFIIRVTDNGIGISKEEQKKIFHPFYQAMDNKPGTGIGLSIVKSIVESHNGC
EEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCE
IEVESEVNKGSSFIVTLPVEQVQVLPQDTGTSLLNNPTIPEGILQEDLSGSPIKHKPTML
EEEECCCCCCCEEEEEECHHHHEECCCCCCCHHHCCCCCCHHHHHHCCCCCCCCCCCEEE
IVDDNEEMLNFLSSSLTDKYSILTAEDGIEALNKLKENEVTLIVSDWMMPRMDGVEFCKA
EECCCHHHHHHHHHHCCCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHH
IRTNQATSHIPFILLTAKTDTNSKIEGMDCGADAYIEKPFSMQYLEACIKNLVDLRNLLR
HHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHH
QKFSKMPLVPLNSIANNSMDDKFLTRMNEIIEENFSNPELSVDFLAEKLCISRSGLFAKI
HHHHCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHCCCCHHHHH
KTLANITPNELIQVVRLKKAAILLAENKYRINEICYMVGFNNPSYFSKCFQKQFGMKPGE
HHHHCCCHHHHHHHHHHHHEEEEEECCCEEEEEEEEEEECCCHHHHHHHHHHHHCCCCCH
FVNGKREE
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]