Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 150003660

GI number: 150003660

Start: 1450028

End: 1452175

Strand: Direct

Name: rnr [H]

Synonym: BVU_1091

Alternate gene names: 150003660

Gene position: 1450028-1452175 (Clockwise)

Preceding gene: 150003654

Following gene: 150003661

Centisome position: 28.08

GC content: 44.23

Gene sequence:

>2148_bases
ATGGCTAAAAAGAAAGAAAAAAAAGCAGGGAAACGCATGAAAAAAAGCGAAATGTCTGAACGACTGATAAGCTTATTCCA
CACAAAACCGAACGAAACATTCAGTCTGAAACAATTATCAAGCAGTCTGAACCTTACTACACATCCTCTTAAAATGCTTT
GTGCCGACATCATTACTGAAATGATTGAGGATGATTTTCTGCAAGAAGTAGAAAAAGGACACTACAAACTGAACGACCAC
GGTCTGATTATGACTGGCGTCTTTCAGCGTAAAAGCAACGGCAAGAACTCCTTCATCCCCGATGATGGTGGAGAAACTAT
TTTCATAGCCGAACGTAATTCGGCACATGCCATGAATAATGACAAAGTAAAAATAGCCCTCTTTGCCAAACGTAAGAACC
GGAACCCGGAAGGTGAAGTGATAGAGATTCTGGAACGTGCCAACGATACTTTTGTCGGCACACTGAAAGTAGAGAAATTC
TACGCCTTTCTGCTGACCGAGAACCGCACTCTGGCAAATGATATTTTTATCCCGAAAGATAAGCTGAAAGGTGGAAAGAA
TGGGGACAAAGCAGTCGTGAAAATTGTAGAATGGCCCGAAGAGGCAAAAAACCCGATAGGACAAGTCATTGATATTTTGG
GAAAAGCAGGAGAAAACACAACTGAAATGCATGCCATTCTGGCCGAATTCGGCTTACCTTACGTATATCCCAAGAATGTA
GAAACCGCTGCCGAAAAGATTCCGGCAGAGATTTCCGAGGCGGACTATGCAGAACGTGAAGATTTCCGCAATGTAACAAC
TTTCACCATTGACCCTAAAGATGCAAAGGACTTTGATGACGCGCTCTCCATCCGTCTCATCAAACCGGGACTATGGGAAG
TAGGCGTACACATTGCCGATGTTACTCATTATGTAAAAGAAGGAGGCGTTATCGACAAAGAAGCTGAAAAACGCGCTACT
TCCGTTTATCTGGTAGACCGTACCATCCCCATGTTGCCCGAACGGCTGTGTAACTTCATCTGTTCCCTCCGCCCCGACGA
AGAGAAACTGGCATTCTCCGTCATTTTCAATATGAATGAAAAGGGAGAGGTGAAAGACTCGCGCATCGTGCACACCATTA
TAAAGAGCGACCGCCGTTTCACCTATGAGGAGGCGCAAAAAGTGATTGAAACGGGTGAAGGCGACTACAAAGAAGAAATT
CTGGAACTGAACAAACTGGCACAAATCCTGCGTAAACAAAGATTGGCTGCCGGTGCTATTGACTTTGACCGCGTAGAAGT
GAAATTTGAGATAGACGAAACCGGCAAACCGCTCAGTGTCTACTTCAAAGAATCCAAAGAGGCCAATAAGTTGATAGAGG
AATTTATGTTGTTGGCCAACCGCACGGTTGCCGAAAAAATCGGTAAAGTACCTAAAAACAAGAAAGCCAAAGTATTCCCT
TATCGTATCCACGACCTTCCGGACCCCGATAAACTGGAGAACTTGAATTGGTTTATCAATCGCTTCGGATATAAGATACG
TACATCGGGTAGCAAAACTGAGATATCCAAATCCATCAATCGTTTACTGGACGACATAAAGAACAAGAAAGAACAAAATC
TGGTGGAAACCGTATCCTTGCGTGCCATGCAAAAGGCCCGTTATTCCACACATAATATTGGCCACTATGGTCTGGCATTT
GACTATTATACTCACTTTACCTCACCTATCCGCCGTTTTCCGGATATGATGGTTCATCGTCTGCTCACCCGCTATCTGGC
AGGAGGACGTACGGTACAGGAAGCGAAATACGAAGAATTGTGTGACCATAGCTCTGAAATGGAACAAATCGCCGCCAATG
CGGAACGTGCCTCTGTAAAATACAAACAAGTAGAGTTTATGGGTGAACGTTTGGGCATGGAGTTCGATGGAGTCATTTCC
GGAGTTACCGAATGGGGACTTTATGTGGAACTGAACGAAAACAAGTGCGAAGGTATGATTCCCATGCGTGACCTTGGTGA
TGACTATTATGATTTCGATGAAAAGAACTATTGTCTGACGGGACGCCGGCATCACAAAAAATTCAGTTTGGGAGATCCGG
TTACCATTAAAGTGGCCCGCGCCAATCTGGAGAAAAAGCAACTTGATTTCGCTTTGGTCGAGAAATAA

Upstream 100 bases:

>100_bases
ACGTTTCATTTAGATTCAACCAAATTTAATGTATCTATTGAACCGCTATTCCAATTATTTTGTTTACTTTGTAGCACATA
ATACATAAATATATCCCCTT

Downstream 100 bases:

>100_bases
AGATTAACATCCTGTTGTAGGGGCAGACTGGTTCTTCCCCTACAACAAGACAATAGTTTCATTTACTTCACTCTTCTATT
CAACTGATTATTCGCTTTAT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 715; Mature: 714

Protein sequence:

>715_residues
MAKKKEKKAGKRMKKSEMSERLISLFHTKPNETFSLKQLSSSLNLTTHPLKMLCADIITEMIEDDFLQEVEKGHYKLNDH
GLIMTGVFQRKSNGKNSFIPDDGGETIFIAERNSAHAMNNDKVKIALFAKRKNRNPEGEVIEILERANDTFVGTLKVEKF
YAFLLTENRTLANDIFIPKDKLKGGKNGDKAVVKIVEWPEEAKNPIGQVIDILGKAGENTTEMHAILAEFGLPYVYPKNV
ETAAEKIPAEISEADYAEREDFRNVTTFTIDPKDAKDFDDALSIRLIKPGLWEVGVHIADVTHYVKEGGVIDKEAEKRAT
SVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSVIFNMNEKGEVKDSRIVHTIIKSDRRFTYEEAQKVIETGEGDYKEEI
LELNKLAQILRKQRLAAGAIDFDRVEVKFEIDETGKPLSVYFKESKEANKLIEEFMLLANRTVAEKIGKVPKNKKAKVFP
YRIHDLPDPDKLENLNWFINRFGYKIRTSGSKTEISKSINRLLDDIKNKKEQNLVETVSLRAMQKARYSTHNIGHYGLAF
DYYTHFTSPIRRFPDMMVHRLLTRYLAGGRTVQEAKYEELCDHSSEMEQIAANAERASVKYKQVEFMGERLGMEFDGVIS
GVTEWGLYVELNENKCEGMIPMRDLGDDYYDFDEKNYCLTGRRHHKKFSLGDPVTIKVARANLEKKQLDFALVEK

Sequences:

>Translated_715_residues
MAKKKEKKAGKRMKKSEMSERLISLFHTKPNETFSLKQLSSSLNLTTHPLKMLCADIITEMIEDDFLQEVEKGHYKLNDH
GLIMTGVFQRKSNGKNSFIPDDGGETIFIAERNSAHAMNNDKVKIALFAKRKNRNPEGEVIEILERANDTFVGTLKVEKF
YAFLLTENRTLANDIFIPKDKLKGGKNGDKAVVKIVEWPEEAKNPIGQVIDILGKAGENTTEMHAILAEFGLPYVYPKNV
ETAAEKIPAEISEADYAEREDFRNVTTFTIDPKDAKDFDDALSIRLIKPGLWEVGVHIADVTHYVKEGGVIDKEAEKRAT
SVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSVIFNMNEKGEVKDSRIVHTIIKSDRRFTYEEAQKVIETGEGDYKEEI
LELNKLAQILRKQRLAAGAIDFDRVEVKFEIDETGKPLSVYFKESKEANKLIEEFMLLANRTVAEKIGKVPKNKKAKVFP
YRIHDLPDPDKLENLNWFINRFGYKIRTSGSKTEISKSINRLLDDIKNKKEQNLVETVSLRAMQKARYSTHNIGHYGLAF
DYYTHFTSPIRRFPDMMVHRLLTRYLAGGRTVQEAKYEELCDHSSEMEQIAANAERASVKYKQVEFMGERLGMEFDGVIS
GVTEWGLYVELNENKCEGMIPMRDLGDDYYDFDEKNYCLTGRRHHKKFSLGDPVTIKVARANLEKKQLDFALVEK
>Mature_714_residues
AKKKEKKAGKRMKKSEMSERLISLFHTKPNETFSLKQLSSSLNLTTHPLKMLCADIITEMIEDDFLQEVEKGHYKLNDHG
LIMTGVFQRKSNGKNSFIPDDGGETIFIAERNSAHAMNNDKVKIALFAKRKNRNPEGEVIEILERANDTFVGTLKVEKFY
AFLLTENRTLANDIFIPKDKLKGGKNGDKAVVKIVEWPEEAKNPIGQVIDILGKAGENTTEMHAILAEFGLPYVYPKNVE
TAAEKIPAEISEADYAEREDFRNVTTFTIDPKDAKDFDDALSIRLIKPGLWEVGVHIADVTHYVKEGGVIDKEAEKRATS
VYLVDRTIPMLPERLCNFICSLRPDEEKLAFSVIFNMNEKGEVKDSRIVHTIIKSDRRFTYEEAQKVIETGEGDYKEEIL
ELNKLAQILRKQRLAAGAIDFDRVEVKFEIDETGKPLSVYFKESKEANKLIEEFMLLANRTVAEKIGKVPKNKKAKVFPY
RIHDLPDPDKLENLNWFINRFGYKIRTSGSKTEISKSINRLLDDIKNKKEQNLVETVSLRAMQKARYSTHNIGHYGLAFD
YYTHFTSPIRRFPDMMVHRLLTRYLAGGRTVQEAKYEELCDHSSEMEQIAANAERASVKYKQVEFMGERLGMEFDGVISG
VTEWGLYVELNENKCEGMIPMRDLGDDYYDFDEKNYCLTGRRHHKKFSLGDPVTIKVARANLEKKQLDFALVEK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=607, Percent_Identity=31.6309719934102, Blast_Score=274, Evalue=3e-73,
Organism=Homo sapiens, GI190014623, Length=607, Percent_Identity=31.6309719934102, Blast_Score=274, Evalue=3e-73,
Organism=Homo sapiens, GI134288890, Length=485, Percent_Identity=34.2268041237113, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI19115966, Length=550, Percent_Identity=29.8181818181818, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI219521928, Length=547, Percent_Identity=29.4332723948812, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI156105695, Length=465, Percent_Identity=26.8817204301075, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI156105693, Length=464, Percent_Identity=26.5086206896552, Blast_Score=136, Evalue=7e-32,
Organism=Escherichia coli, GI87082383, Length=627, Percent_Identity=30.9409888357257, Blast_Score=322, Evalue=5e-89,
Organism=Escherichia coli, GI1787542, Length=580, Percent_Identity=24.1379310344828, Blast_Score=126, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI212645896, Length=706, Percent_Identity=29.6033994334278, Blast_Score=254, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17553506, Length=505, Percent_Identity=33.8613861386139, Blast_Score=245, Evalue=7e-65,
Organism=Saccharomyces cerevisiae, GI6324552, Length=610, Percent_Identity=32.2950819672131, Blast_Score=243, Evalue=9e-65,
Organism=Saccharomyces cerevisiae, GI6320499, Length=414, Percent_Identity=24.6376811594203, Blast_Score=104, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323943, Length=425, Percent_Identity=23.7647058823529, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24649634, Length=619, Percent_Identity=31.9870759289176, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI19922976, Length=543, Percent_Identity=32.4125230202578, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24654597, Length=543, Percent_Identity=32.4125230202578, Blast_Score=234, Evalue=2e-61,
Organism=Drosophila melanogaster, GI24654592, Length=543, Percent_Identity=32.4125230202578, Blast_Score=234, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 81950; Mature: 81819

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKEKKAGKRMKKSEMSERLISLFHTKPNETFSLKQLSSSLNLTTHPLKMLCADIITE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHHH
MIEDDFLQEVEKGHYKLNDHGLIMTGVFQRKSNGKNSFIPDDGGETIFIAERNSAHAMNN
HHHHHHHHHHHCCCEEECCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
DKVKIALFAKRKNRNPEGEVIEILERANDTFVGTLKVEKFYAFLLTENRTLANDIFIPKD
CCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEHHHEEEEEEECCCCHHCCCCCCHH
KLKGGKNGDKAVVKIVEWPEEAKNPIGQVIDILGKAGENTTEMHAILAEFGLPYVYPKNV
HCCCCCCCCHHEEEEEECCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCH
ETAAEKIPAEISEADYAEREDFRNVTTFTIDPKDAKDFDDALSIRLIKPGLWEVGVHIAD
HHHHHHCCCHHHHCCCHHHHHCCCCEEEEECCCCCCCCHHHHEEEEECCCHHHHHHHHHH
VTHYVKEGGVIDKEAEKRATSVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSVIFNMNE
HHHHHHHCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEECCC
KGEVKDSRIVHTIIKSDRRFTYEEAQKVIETGEGDYKEEILELNKLAQILRKQRLAAGAI
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DFDRVEVKFEIDETGKPLSVYFKESKEANKLIEEFMLLANRTVAEKIGKVPKNKKAKVFP
CEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
YRIHDLPDPDKLENLNWFINRFGYKIRTSGSKTEISKSINRLLDDIKNKKEQNLVETVSL
EEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RAMQKARYSTHNIGHYGLAFDYYTHFTSPIRRFPDMMVHRLLTRYLAGGRTVQEAKYEEL
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
CDHSSEMEQIAANAERASVKYKQVEFMGERLGMEFDGVISGVTEWGLYVELNENKCEGMI
HCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCC
PMRDLGDDYYDFDEKNYCLTGRRHHKKFSLGDPVTIKVARANLEKKQLDFALVEK
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCC
>Mature Secondary Structure 
AKKKEKKAGKRMKKSEMSERLISLFHTKPNETFSLKQLSSSLNLTTHPLKMLCADIITE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCHHHHHHHHHHHHHH
MIEDDFLQEVEKGHYKLNDHGLIMTGVFQRKSNGKNSFIPDDGGETIFIAERNSAHAMNN
HHHHHHHHHHHCCCEEECCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCC
DKVKIALFAKRKNRNPEGEVIEILERANDTFVGTLKVEKFYAFLLTENRTLANDIFIPKD
CCEEEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEEHHHEEEEEEECCCCHHCCCCCCHH
KLKGGKNGDKAVVKIVEWPEEAKNPIGQVIDILGKAGENTTEMHAILAEFGLPYVYPKNV
HCCCCCCCCHHEEEEEECCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCH
ETAAEKIPAEISEADYAEREDFRNVTTFTIDPKDAKDFDDALSIRLIKPGLWEVGVHIAD
HHHHHHCCCHHHHCCCHHHHHCCCCEEEEECCCCCCCCHHHHEEEEECCCHHHHHHHHHH
VTHYVKEGGVIDKEAEKRATSVYLVDRTIPMLPERLCNFICSLRPDEEKLAFSVIFNMNE
HHHHHHHCCCCCCHHHHHHCEEEEECCCCHHHHHHHHHHHHCCCCCHHHEEEEEEEECCC
KGEVKDSRIVHTIIKSDRRFTYEEAQKVIETGEGDYKEEILELNKLAQILRKQRLAAGAI
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DFDRVEVKFEIDETGKPLSVYFKESKEANKLIEEFMLLANRTVAEKIGKVPKNKKAKVFP
CEEEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCEEEE
YRIHDLPDPDKLENLNWFINRFGYKIRTSGSKTEISKSINRLLDDIKNKKEQNLVETVSL
EEECCCCCCHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
RAMQKARYSTHNIGHYGLAFDYYTHFTSPIRRFPDMMVHRLLTRYLAGGRTVQEAKYEEL
HHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
CDHSSEMEQIAANAERASVKYKQVEFMGERLGMEFDGVISGVTEWGLYVELNENKCEGMI
HCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEECCCCCCCCC
PMRDLGDDYYDFDEKNYCLTGRRHHKKFSLGDPVTIKVARANLEKKQLDFALVEK
CHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]