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The map label for this gene is luxQ [H]

Identifier: 150003606

GI number: 150003606

Start: 1372306

End: 1374729

Strand: Reverse

Name: luxQ [H]

Synonym: BVU_1035

Alternate gene names: 150003606

Gene position: 1374729-1372306 (Counterclockwise)

Preceding gene: 150003608

Following gene: 150003573

Centisome position: 26.63

GC content: 41.25

Gene sequence:

>2424_bases
ATGGGGAAGATTCAAGAGAATGATGCAAGGTTGCAGCAGCTTGTATCAATGGCACGCATAGGATGGTGGGAGGTGGACTT
TGATGAAGGAGTTTACTATTGTTCTGAGTTTGTAGCCGATTTGTTAGGAATAGAAGGGAATAAGATTTCTGCTAAAGATT
TCGCGAATCTGATTTGTGAGAATTATCGGGAGCGTATTTTGGAGGAATTTCGCTCTTTCCGGATGATGGAGATTTATGAG
CAGGTTTTTCCGATACATTCCAAATATGGGATGATGTGGGTCAGTACCAAGGTCGGTGAGAAGCGTATTACCAAAGAAGG
TCATGTCCGCGTCATGGGTATGTTGCAATGTATTTCCCGGCAACGGATGAATATGCAGGAGCAGACGGTAGACCGGTTGA
ACTCTTTATTATCTCGTTTGAACGGCATTTCCAAGTCATTGCTTGATTTTTTGCATTCTGATGATATTACCTTGGTTATC
AATAAGATTTTAAAGGAGGTATTGCGCCAATTTCAAGCAGATCGTACTTATATTTTTGAATTGGACAGGAAATTGCATAC
GGAAGTCTGTACCTATGAAATAGCAGTGGAGGGTATAAAAGAACGTAAGGTTTTATTGTCGGAATCTTCTATTGATTATG
CCTCTTGGTGGACAGGACAGATATTGGCTGGTAATCCTATCATTCTTTTTACATTAAATTTGCTTCCTGATTCAGCCGGG
GCGGATAAGCGTAGATTAGAGGAATATGGAGTGAAATCTACTATGGTGGTGCCTTTGAACTCAAAAGACGGAGTGTGGGG
GTATATAGGGGTGGATATGGTGCGTGAACACCGGAATTGGTGCAATGAGGATTATCAATGGTTTGTCTCTTTGGGTAATA
TTATCAGTATTTGTATGGAATTGAGACGCTCTGAATCTGAAGCCCGGCTGGAAAAAGCTTATTTGCAGAATATTTATAAG
AATCTTCCTGCTGGTATCGAGTTGTATGATAAGGATGGGTTTATGACAGATTTGAATGACAAGGAGATGGAAATCTTCGG
TCTCCGGCATAAGGAGGATGTGATAGGATTGAATTTATTTGATAATCCTTTGCTGCCGCAGGGGTTGAAAGATAAGTTGA
AAGCAGGAGCACCTATTGATATGTCGTTTAATTATGATTTCGACCGTTTGGACGGCTATTATTCTACTTCTCGCACCGGT
ACTATCAGTTTGATCTCGAAATTCGCTCCACTTTATGATGCTTTGGGCAATCTGATAAATATATTGTTGATCAATATTGA
TAATACGGAAACAACAAATGCATATAGCAAAATACAGGACTTTGAGGAGTTTTTCACATTGATTGGTAACTATGCCAAAG
TAGGATATGCCCATTTTAATGCCTTGAAATGTGATGGCTATGCTGTGAATAGCTGGTATCGGAATGTAGGTGAGAAAGAA
GGAACTCCATTGAATGAGATTATCAAAGTGCATTCTCATTTTCATCCGGATGATCGCAGGATGATGCTTCGCTTCTTTGA
TCAGGTATTGATACGGGAAGCCAGCCATCTGAGGCGTGATGTGCGTATATTATGTGAAGATGGCACGTATACATGGACAA
GAGTCAATGTAATGGTACGCGATTTTCGTCCGGAAGACGGGATTATTGATATGGTTTGTGTCAATTATGACATAACTGAA
CTGAAAGAAACGGAGCGGAAGTTGATAGCGGCAAGAGATAAAGCGGAAGAGCTGGATCGTTTGAAATCCGCTTTTCTGGC
TAATATGAGTCATGAGATCCGCACTCCGCTGAATGCTATAGTGGGGTTTTCCAGCCTTTTAACGGAAACGGAAGATATGA
AGGACCGCAAGCAGTACATGGCTATTGTACAGGAGAATACGGAGTTGCTTCTTCAGCTTATTTCAGATATTCTTGATTTA
TCGAAGATGGAGTCGGGAGCTTTTGAATTTGTCAAGAGTGATACGGATGTCAATCTGCTTTGCAGTGAGATTATCCGTTC
TTTACGCATGAAAGTGCCGGCCGGTGTGGAGCTGGTGTTTGAAGAATGCTTGCCCGGATGTCATGTATGGGCAGACAAGA
ATCGTTTGAATCAAGTCATTTCCAATTTCATTAATAACGCTTTGAAGTTCACTTTTTCGGGCAGCATAACGTTAGGATAT
TATAGGCAGACAGATGGGTATCTGCGGTTTTATGTTCGTGATACAGGAATGGGAATCCCGAAGAATAAGATAAAAACAGT
ATTTGACCGTTTTGTGAAACTGAACAGTTTTGTTCATGGTACGGGACTTGGCTTGTCTATTTGTAAGAGTCTGGTGGAAC
AGATGGGTGGAACTATCGGTGTGGAGTCAGAAGAAGGAGAAGGCTCTTGCTTTTGGTTTACTTATCCTTATCAGGAAATG
GCTGGTAGTATTCTGGTACCGTAG

Upstream 100 bases:

>100_bases
CATTGATTATTTATTGCCGGTGTTTATTTTTTCATGTTTAAGTATTTGGTATTGACAGATAATGATTATCTTGGTGCATA
AATTAAAAGGTAGCTTGTAT

Downstream 100 bases:

>100_bases
AGGGGTTTGATTAATAAAGGTTTATAGCTGTAGGGGTGAATTGAGTTCATCCGGATACATTGATTTTGTGGTATCGGGTG
GGAGCATTTCACCCCTACAG

Product: two-component system sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MGKIQENDARLQQLVSMARIGWWEVDFDEGVYYCSEFVADLLGIEGNKISAKDFANLICENYRERILEEFRSFRMMEIYE
QVFPIHSKYGMMWVSTKVGEKRITKEGHVRVMGMLQCISRQRMNMQEQTVDRLNSLLSRLNGISKSLLDFLHSDDITLVI
NKILKEVLRQFQADRTYIFELDRKLHTEVCTYEIAVEGIKERKVLLSESSIDYASWWTGQILAGNPIILFTLNLLPDSAG
ADKRRLEEYGVKSTMVVPLNSKDGVWGYIGVDMVREHRNWCNEDYQWFVSLGNIISICMELRRSESEARLEKAYLQNIYK
NLPAGIELYDKDGFMTDLNDKEMEIFGLRHKEDVIGLNLFDNPLLPQGLKDKLKAGAPIDMSFNYDFDRLDGYYSTSRTG
TISLISKFAPLYDALGNLINILLINIDNTETTNAYSKIQDFEEFFTLIGNYAKVGYAHFNALKCDGYAVNSWYRNVGEKE
GTPLNEIIKVHSHFHPDDRRMMLRFFDQVLIREASHLRRDVRILCEDGTYTWTRVNVMVRDFRPEDGIIDMVCVNYDITE
LKETERKLIAARDKAEELDRLKSAFLANMSHEIRTPLNAIVGFSSLLTETEDMKDRKQYMAIVQENTELLLQLISDILDL
SKMESGAFEFVKSDTDVNLLCSEIIRSLRMKVPAGVELVFEECLPGCHVWADKNRLNQVISNFINNALKFTFSGSITLGY
YRQTDGYLRFYVRDTGMGIPKNKIKTVFDRFVKLNSFVHGTGLGLSICKSLVEQMGGTIGVESEEGEGSCFWFTYPYQEM
AGSILVP

Sequences:

>Translated_807_residues
MGKIQENDARLQQLVSMARIGWWEVDFDEGVYYCSEFVADLLGIEGNKISAKDFANLICENYRERILEEFRSFRMMEIYE
QVFPIHSKYGMMWVSTKVGEKRITKEGHVRVMGMLQCISRQRMNMQEQTVDRLNSLLSRLNGISKSLLDFLHSDDITLVI
NKILKEVLRQFQADRTYIFELDRKLHTEVCTYEIAVEGIKERKVLLSESSIDYASWWTGQILAGNPIILFTLNLLPDSAG
ADKRRLEEYGVKSTMVVPLNSKDGVWGYIGVDMVREHRNWCNEDYQWFVSLGNIISICMELRRSESEARLEKAYLQNIYK
NLPAGIELYDKDGFMTDLNDKEMEIFGLRHKEDVIGLNLFDNPLLPQGLKDKLKAGAPIDMSFNYDFDRLDGYYSTSRTG
TISLISKFAPLYDALGNLINILLINIDNTETTNAYSKIQDFEEFFTLIGNYAKVGYAHFNALKCDGYAVNSWYRNVGEKE
GTPLNEIIKVHSHFHPDDRRMMLRFFDQVLIREASHLRRDVRILCEDGTYTWTRVNVMVRDFRPEDGIIDMVCVNYDITE
LKETERKLIAARDKAEELDRLKSAFLANMSHEIRTPLNAIVGFSSLLTETEDMKDRKQYMAIVQENTELLLQLISDILDL
SKMESGAFEFVKSDTDVNLLCSEIIRSLRMKVPAGVELVFEECLPGCHVWADKNRLNQVISNFINNALKFTFSGSITLGY
YRQTDGYLRFYVRDTGMGIPKNKIKTVFDRFVKLNSFVHGTGLGLSICKSLVEQMGGTIGVESEEGEGSCFWFTYPYQEM
AGSILVP
>Mature_806_residues
GKIQENDARLQQLVSMARIGWWEVDFDEGVYYCSEFVADLLGIEGNKISAKDFANLICENYRERILEEFRSFRMMEIYEQ
VFPIHSKYGMMWVSTKVGEKRITKEGHVRVMGMLQCISRQRMNMQEQTVDRLNSLLSRLNGISKSLLDFLHSDDITLVIN
KILKEVLRQFQADRTYIFELDRKLHTEVCTYEIAVEGIKERKVLLSESSIDYASWWTGQILAGNPIILFTLNLLPDSAGA
DKRRLEEYGVKSTMVVPLNSKDGVWGYIGVDMVREHRNWCNEDYQWFVSLGNIISICMELRRSESEARLEKAYLQNIYKN
LPAGIELYDKDGFMTDLNDKEMEIFGLRHKEDVIGLNLFDNPLLPQGLKDKLKAGAPIDMSFNYDFDRLDGYYSTSRTGT
ISLISKFAPLYDALGNLINILLINIDNTETTNAYSKIQDFEEFFTLIGNYAKVGYAHFNALKCDGYAVNSWYRNVGEKEG
TPLNEIIKVHSHFHPDDRRMMLRFFDQVLIREASHLRRDVRILCEDGTYTWTRVNVMVRDFRPEDGIIDMVCVNYDITEL
KETERKLIAARDKAEELDRLKSAFLANMSHEIRTPLNAIVGFSSLLTETEDMKDRKQYMAIVQENTELLLQLISDILDLS
KMESGAFEFVKSDTDVNLLCSEIIRSLRMKVPAGVELVFEECLPGCHVWADKNRLNQVISNFINNALKFTFSGSITLGYY
RQTDGYLRFYVRDTGMGIPKNKIKTVFDRFVKLNSFVHGTGLGLSICKSLVEQMGGTIGVESEEGEGSCFWFTYPYQEMA
GSILVP

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=37.3015873015873, Blast_Score=147, Evalue=3e-36,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=35.4700854700855, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=33.4728033472803, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI87081816, Length=248, Percent_Identity=35.8870967741936, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1788713, Length=256, Percent_Identity=32.03125, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI1786912, Length=232, Percent_Identity=31.0344827586207, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786600, Length=273, Percent_Identity=28.2051282051282, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=214, Percent_Identity=28.5046728971963, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788393, Length=215, Percent_Identity=30.2325581395349, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=27.1966527196653, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=242, Percent_Identity=26.0330578512397, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=250, Percent_Identity=24.4, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=209, Percent_Identity=29.1866028708134, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=25.8215962441315, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 92896; Mature: 92765

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKIQENDARLQQLVSMARIGWWEVDFDEGVYYCSEFVADLLGIEGNKISAKDFANLICE
CCCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NYRERILEEFRSFRMMEIYEQVFPIHSKYGMMWVSTKVGEKRITKEGHVRVMGMLQCISR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCHHHCCCCCCHHHHHHHHHHHH
QRMNMQEQTVDRLNSLLSRLNGISKSLLDFLHSDDITLVINKILKEVLRQFQADRTYIFE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEH
LDRKLHTEVCTYEIAVEGIKERKVLLSESSIDYASWWTGQILAGNPIILFTLNLLPDSAG
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHCCCCEEEECCCEEEEEEEECCCCCC
ADKRRLEEYGVKSTMVVPLNSKDGVWGYIGVDMVREHRNWCNEDYQWFVSLGNIISICME
CHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LRRSESEARLEKAYLQNIYKNLPAGIELYDKDGFMTDLNDKEMEIFGLRHKEDVIGLNLF
HHHCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEECCCCCCEEEEEEC
DNPLLPQGLKDKLKAGAPIDMSFNYDFDRLDGYYSTSRTGTISLISKFAPLYDALGNLIN
CCCCCCCCHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHE
ILLINIDNTETTNAYSKIQDFEEFFTLIGNYAKVGYAHFNALKCDGYAVNSWYRNVGEKE
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEHHHHHHHCCCCC
GTPLNEIIKVHSHFHPDDRRMMLRFFDQVLIREASHLRRDVRILCEDGTYTWTRVNVMVR
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEEEE
DFRPEDGIIDMVCVNYDITELKETERKLIAARDKAEELDRLKSAFLANMSHEIRTPLNAI
ECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VGFSSLLTETEDMKDRKQYMAIVQENTELLLQLISDILDLSKMESGAFEFVKSDTDVNLL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
CSEIIRSLRMKVPAGVELVFEECLPGCHVWADKNRLNQVISNFINNALKFTFSGSITLGY
HHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHEEEEEECCEEEEE
YRQTDGYLRFYVRDTGMGIPKNKIKTVFDRFVKLNSFVHGTGLGLSICKSLVEQMGGTIG
EEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
VESEEGEGSCFWFTYPYQEMAGSILVP
CCCCCCCCCEEEEECCHHHHCCCCCCC
>Mature Secondary Structure 
GKIQENDARLQQLVSMARIGWWEVDFDEGVYYCSEFVADLLGIEGNKISAKDFANLICE
CCCCCHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NYRERILEEFRSFRMMEIYEQVFPIHSKYGMMWVSTKVGEKRITKEGHVRVMGMLQCISR
HHHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEECCCHHHCCCCCCHHHHHHHHHHHH
QRMNMQEQTVDRLNSLLSRLNGISKSLLDFLHSDDITLVINKILKEVLRQFQADRTYIFE
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEH
LDRKLHTEVCTYEIAVEGIKERKVLLSESSIDYASWWTGQILAGNPIILFTLNLLPDSAG
HHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHCCCCEEEECCCEEEEEEEECCCCCC
ADKRRLEEYGVKSTMVVPLNSKDGVWGYIGVDMVREHRNWCNEDYQWFVSLGNIISICME
CHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LRRSESEARLEKAYLQNIYKNLPAGIELYDKDGFMTDLNDKEMEIFGLRHKEDVIGLNLF
HHHCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEECCCCCCEEEEECCCCCCEEEEEEC
DNPLLPQGLKDKLKAGAPIDMSFNYDFDRLDGYYSTSRTGTISLISKFAPLYDALGNLIN
CCCCCCCCHHHHHCCCCCEEEECCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHE
ILLINIDNTETTNAYSKIQDFEEFFTLIGNYAKVGYAHFNALKCDGYAVNSWYRNVGEKE
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEHHHHHHHCCCCC
GTPLNEIIKVHSHFHPDDRRMMLRFFDQVLIREASHLRRDVRILCEDGTYTWTRVNVMVR
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEEEEEEE
DFRPEDGIIDMVCVNYDITELKETERKLIAARDKAEELDRLKSAFLANMSHEIRTPLNAI
ECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
VGFSSLLTETEDMKDRKQYMAIVQENTELLLQLISDILDLSKMESGAFEFVKSDTDVNLL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHH
CSEIIRSLRMKVPAGVELVFEECLPGCHVWADKNRLNQVISNFINNALKFTFSGSITLGY
HHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHEEEEEECCEEEEE
YRQTDGYLRFYVRDTGMGIPKNKIKTVFDRFVKLNSFVHGTGLGLSICKSLVEQMGGTIG
EEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEE
VESEEGEGSCFWFTYPYQEMAGSILVP
CCCCCCCCCEEEEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7984107 [H]