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The map label for this gene is aslA [H]

Identifier: 150003571

GI number: 150003571

Start: 1321868

End: 1323430

Strand: Direct

Name: aslA [H]

Synonym: BVU_1000

Alternate gene names: 150003571

Gene position: 1321868-1323430 (Clockwise)

Preceding gene: 150003570

Following gene: 150003574

Centisome position: 25.6

GC content: 47.09

Gene sequence:

>1563_bases
ATGAAAAGTAGAAATTATGCAGGCATATCCTTACTTGCCTCATTAGCCGCCTGTACCTCTGCAACAGCAGAAACCGTTCA
AAAAAACAGTACGCAGGCCCCCAAAAAGCCCAATGTTATCGTTATTCTGGCAGATGACCTAGGATATGGAGATTTAAAAT
GTTACGGAGCCAAGAATGTAGAAACTCCCCATGTTGACAAACTGGCATCGGAAGGCATTCGTTTTACTAATGCACATACC
GTAGCCGCTACCAGCACCCCATCCCGCTACTCCTTGCTGACAGGAGAATATGCATGGCGCAGACCGGACACGGACATTGC
CGCAGGAGATGTAAAAATGATTATCCGTCCCGAACAATACACCATGGCAGACATGTTTAAAAGTGCCGGATATGCTACAG
CCGCCATCGGCAAATGGCATCTGGGCCTGGGAGACAAGACAGGCGGACAGGATTGGAATGCTCCTTTACCAGCCGCTTTA
GGTGACTTAGGCTTTGACTATCACTATATCATGGCCGCTACAGCCGACCGTGTACCTTGTGTATTTATAGAAAACGGCAA
GGTAGCCAACTATGATCCGTCCGATCCCATAGAAGTGAGTTACACCAAGAACTTTCCGGGAGAACCGACCGGCAAAGATA
ATCCCGAATTACTGTATAACCTACATCCCAGCAACGGACATGACATGTCCATCGTCAATGGTATCAGCCGCATCGGATTT
ATGAAAGGGGGCGGAAAAGCACTTTGGAAAGACGAGAACATTGCCGATTCCATCACCGTTCATGCCATCGACTTTATCAA
ACAGCATAAAGACGAGCCTTTCTTTATGTATTTTGCAACCAATGATGTACACGTTCCTCGTTTTCCCCATGACCGCTTCC
GTGGAAAGAATCCTATGGGACTACGCGGAGACGCAATCGCCCAATTCGACTGGACGGTAGGCCAGCTGATGGAAACATTG
GACCAACTTGGACTAACTGAAAACACGCTGATTATTCTATCCAGCGACAATGGTCCGGTTGTAGACGACGGATATAAGGA
CAAGGCAGAAGAGTTGTTGAACGGACATACACCTTCCGGTCCGTGGAGAGGAAACAAATACAGCGCTTTCGAGGGTGGAA
CAGCCGTTCCGGTCATTGTCCGCTGGCCACAGAAGATAAAACAGACAGGAGACTCGGACGTATTAATGTCACAGATTGAC
TGGCTAGCCTCTTTAGGAGCTTTGATCAACGCCAGATTACCTAAAGGCAGCGCTCCGGACAGTTATGACCGTTTAGGGAA
TCTGATAGGAACCGACAAGACAGACCGCCCCTGGATTGTGGAACAATCCATGAACCACACGTTGTCCGTCCGTACCAAAG
ACTGGAAATACATTGAACCGAATGATGATCCCACTACCTTTATGAAAGCAGAAAAAATAGAAACCGGAAACCTGAACGTT
CCCCAGTTATATGAAATGGAAAAGGTGAGCGAACAAGAGAATGTAGCAGAAAAGTATCCTGAGAAAGTATTTGAGTTGCA
GACCATTCTGAGGCAAGTACGCAATAAGAGAATAAAGATGTAA

Upstream 100 bases:

>100_bases
AAGATTTTCTTGATAACTTTCCGTCGTTCTTCACCTTCAGGTCGAGAAACCGGAAAGTGAAAATAGACATGTATCCGGAT
CAAACCTTAAATAAATAGAG

Downstream 100 bases:

>100_bases
ACAGGACTCATCCAATAAGAGGATATTTCAAAAATTCGAAATAACCATCAAATGTTCCACCGTATGGGCAGGCCCATGAG
CCCGCCCATACAACATAACG

Product: putative arylsulfatase

Products: NA

Alternate protein names: AS; Aryl-sulfate sulphohydrolase [H]

Number of amino acids: Translated: 520; Mature: 520

Protein sequence:

>520_residues
MKSRNYAGISLLASLAACTSATAETVQKNSTQAPKKPNVIVILADDLGYGDLKCYGAKNVETPHVDKLASEGIRFTNAHT
VAATSTPSRYSLLTGEYAWRRPDTDIAAGDVKMIIRPEQYTMADMFKSAGYATAAIGKWHLGLGDKTGGQDWNAPLPAAL
GDLGFDYHYIMAATADRVPCVFIENGKVANYDPSDPIEVSYTKNFPGEPTGKDNPELLYNLHPSNGHDMSIVNGISRIGF
MKGGGKALWKDENIADSITVHAIDFIKQHKDEPFFMYFATNDVHVPRFPHDRFRGKNPMGLRGDAIAQFDWTVGQLMETL
DQLGLTENTLIILSSDNGPVVDDGYKDKAEELLNGHTPSGPWRGNKYSAFEGGTAVPVIVRWPQKIKQTGDSDVLMSQID
WLASLGALINARLPKGSAPDSYDRLGNLIGTDKTDRPWIVEQSMNHTLSVRTKDWKYIEPNDDPTTFMKAEKIETGNLNV
PQLYEMEKVSEQENVAEKYPEKVFELQTILRQVRNKRIKM

Sequences:

>Translated_520_residues
MKSRNYAGISLLASLAACTSATAETVQKNSTQAPKKPNVIVILADDLGYGDLKCYGAKNVETPHVDKLASEGIRFTNAHT
VAATSTPSRYSLLTGEYAWRRPDTDIAAGDVKMIIRPEQYTMADMFKSAGYATAAIGKWHLGLGDKTGGQDWNAPLPAAL
GDLGFDYHYIMAATADRVPCVFIENGKVANYDPSDPIEVSYTKNFPGEPTGKDNPELLYNLHPSNGHDMSIVNGISRIGF
MKGGGKALWKDENIADSITVHAIDFIKQHKDEPFFMYFATNDVHVPRFPHDRFRGKNPMGLRGDAIAQFDWTVGQLMETL
DQLGLTENTLIILSSDNGPVVDDGYKDKAEELLNGHTPSGPWRGNKYSAFEGGTAVPVIVRWPQKIKQTGDSDVLMSQID
WLASLGALINARLPKGSAPDSYDRLGNLIGTDKTDRPWIVEQSMNHTLSVRTKDWKYIEPNDDPTTFMKAEKIETGNLNV
PQLYEMEKVSEQENVAEKYPEKVFELQTILRQVRNKRIKM
>Mature_520_residues
MKSRNYAGISLLASLAACTSATAETVQKNSTQAPKKPNVIVILADDLGYGDLKCYGAKNVETPHVDKLASEGIRFTNAHT
VAATSTPSRYSLLTGEYAWRRPDTDIAAGDVKMIIRPEQYTMADMFKSAGYATAAIGKWHLGLGDKTGGQDWNAPLPAAL
GDLGFDYHYIMAATADRVPCVFIENGKVANYDPSDPIEVSYTKNFPGEPTGKDNPELLYNLHPSNGHDMSIVNGISRIGF
MKGGGKALWKDENIADSITVHAIDFIKQHKDEPFFMYFATNDVHVPRFPHDRFRGKNPMGLRGDAIAQFDWTVGQLMETL
DQLGLTENTLIILSSDNGPVVDDGYKDKAEELLNGHTPSGPWRGNKYSAFEGGTAVPVIVRWPQKIKQTGDSDVLMSQID
WLASLGALINARLPKGSAPDSYDRLGNLIGTDKTDRPWIVEQSMNHTLSVRTKDWKYIEPNDDPTTFMKAEKIETGNLNV
PQLYEMEKVSEQENVAEKYPEKVFELQTILRQVRNKRIKM

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI53831991, Length=466, Percent_Identity=29.1845493562232, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI146229331, Length=431, Percent_Identity=29.4663573085847, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI146229329, Length=431, Percent_Identity=29.4663573085847, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI6005990, Length=431, Percent_Identity=29.4663573085847, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI146229324, Length=431, Percent_Identity=29.4663573085847, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI31742482, Length=489, Percent_Identity=26.3803680981595, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI157266309, Length=469, Percent_Identity=27.5053304904051, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI71852584, Length=480, Percent_Identity=26.6666666666667, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI45430057, Length=421, Percent_Identity=29.2161520190024, Blast_Score=133, Evalue=5e-31,
Organism=Homo sapiens, GI71852586, Length=363, Percent_Identity=27.5482093663912, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI146229327, Length=345, Percent_Identity=26.9565217391304, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI58743319, Length=143, Percent_Identity=37.7622377622378, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4503899, Length=188, Percent_Identity=29.2553191489362, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI109389362, Length=125, Percent_Identity=38.4, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI38569405, Length=122, Percent_Identity=37.7049180327869, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI38569407, Length=122, Percent_Identity=37.7049180327869, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI59797060, Length=117, Percent_Identity=38.4615384615385, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI4557659, Length=140, Percent_Identity=35.7142857142857, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI5360208, Length=140, Percent_Identity=35.7142857142857, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790233, Length=446, Percent_Identity=27.1300448430493, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI87081924, Length=548, Percent_Identity=25, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790112, Length=407, Percent_Identity=25.3071253071253, Blast_Score=79, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559078, Length=298, Percent_Identity=30.8724832214765, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI115533416, Length=503, Percent_Identity=24.2544731610338, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI115533418, Length=493, Percent_Identity=23.5294117647059, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24666175, Length=395, Percent_Identity=26.5822784810127, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281366397, Length=431, Percent_Identity=25.9860788863109, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281366395, Length=431, Percent_Identity=25.9860788863109, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666163, Length=431, Percent_Identity=25.9860788863109, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24666109, Length=469, Percent_Identity=24.5202558635394, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI281363223, Length=113, Percent_Identity=38.0530973451327, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: =3.1.6.1 [H]

Molecular weight: Translated: 57623; Mature: 57623

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRNYAGISLLASLAACTSATAETVQKNSTQAPKKPNVIVILADDLGYGDLKCYGAKNV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCC
ETPHVDKLASEGIRFTNAHTVAATSTPSRYSLLTGEYAWRRPDTDIAAGDVKMIIRPEQY
CCCCHHHHHHCCCEEECCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCH
TMADMFKSAGYATAAIGKWHLGLGDKTGGQDWNAPLPAALGDLGFDYHYIMAATADRVPC
HHHHHHHHCCCEEEEECEEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCE
VFIENGKVANYDPSDPIEVSYTKNFPGEPTGKDNPELLYNLHPSNGHDMSIVNGISRIGF
EEEECCEECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCE
MKGGGKALWKDENIADSITVHAIDFIKQHKDEPFFMYFATNDVHVPRFPHDRFRGKNPMG
ECCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHCCCCCCC
LRGDAIAQFDWTVGQLMETLDQLGLTENTLIILSSDNGPVVDDGYKDKAEELLNGHTPSG
CCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
PWRGNKYSAFEGGTAVPVIVRWPQKIKQTGDSDVLMSQIDWLASLGALINARLPKGSAPD
CCCCCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SYDRLGNLIGTDKTDRPWIVEQSMNHTLSVRTKDWKYIEPNDDPTTFMKAEKIETGNLNV
HHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEECCCCCCCCEEEEEEECCCCCCC
PQLYEMEKVSEQENVAEKYPEKVFELQTILRQVRNKRIKM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSRNYAGISLLASLAACTSATAETVQKNSTQAPKKPNVIVILADDLGYGDLKCYGAKNV
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCC
ETPHVDKLASEGIRFTNAHTVAATSTPSRYSLLTGEYAWRRPDTDIAAGDVKMIIRPEQY
CCCCHHHHHHCCCEEECCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECCCCH
TMADMFKSAGYATAAIGKWHLGLGDKTGGQDWNAPLPAALGDLGFDYHYIMAATADRVPC
HHHHHHHHCCCEEEEECEEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEEEEECCCCCCE
VFIENGKVANYDPSDPIEVSYTKNFPGEPTGKDNPELLYNLHPSNGHDMSIVNGISRIGF
EEEECCEECCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCE
MKGGGKALWKDENIADSITVHAIDFIKQHKDEPFFMYFATNDVHVPRFPHDRFRGKNPMG
ECCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCEECCCCCHHHHCCCCCCC
LRGDAIAQFDWTVGQLMETLDQLGLTENTLIILSSDNGPVVDDGYKDKAEELLNGHTPSG
CCCCEEEEECCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCC
PWRGNKYSAFEGGTAVPVIVRWPQKIKQTGDSDVLMSQIDWLASLGALINARLPKGSAPD
CCCCCCCCCCCCCCEEEEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SYDRLGNLIGTDKTDRPWIVEQSMNHTLSVRTKDWKYIEPNDDPTTFMKAEKIETGNLNV
HHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCCEEECCCCCCCCEEEEEEECCCCCCC
PQLYEMEKVSEQENVAEKYPEKVFELQTILRQVRNKRIKM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]