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The map label for this gene is dcp [H]

Identifier: 150003563

GI number: 150003563

Start: 1311367

End: 1313454

Strand: Reverse

Name: dcp [H]

Synonym: BVU_0992

Alternate gene names: 150003563

Gene position: 1313454-1311367 (Counterclockwise)

Preceding gene: 150003564

Following gene: 150003562

Centisome position: 25.44

GC content: 42.53

Gene sequence:

>2088_bases
ATGAAAAGACTATTATTTACGTTAGCGACGTGTTGTGTAATGTGTGCATGTGAACAGAAAACAGAAATGAATCCGTTCTT
TACGGAATTCCAGACCGAGTACGGTGCTCCCGATTTTACTAAGATCAGACTGGAGCATTATGAACCTGCTTTCTTGAAAG
GAATAGAGGAGCAGAATGCGGAAATTAAGGCAATAGTTGATAATCCCGAGGAACCTACTTTTGAAAATACCATTGTGGCG
CTGGATAAAAGTGGCGGGATTCTGGCGAGAGTAAGTGGGGTGTTTTTTGCATTGACCGAAGCGGATACAAATGATTCGTT
GACGGCCTTGAATGAAAAGATGGCTCCTGTACTTTCAGAACATAGTGATAATATTTATTTGAATCAGGATTTGTATAAAC
GGGTGGCTGATGTGCATCAACAGGAACAGGAAGGTAAGATAACTCTTACGACTGAGCAACACCGGCTGTTGGACAAGTAT
TATAAAGCTTTTGTCCGTTCGGGTGCCGGACTGGATGCCGGAAAACAATCCCGTTTGAGGGAGATCAATAAAGAATTGTC
GACTTTGGGGATTGCTTTCGACAATCATATCTTAAATGAGAATAACGCTTATCAGTTGGTTATCGAGAATGAGGCTGATT
TGGCCGGGTTACCCGAATGGGTGAAAGCGGGGGCCGCAGAGGAAGCGAAAGCTGCTGGAAAAGAAGGGAAATGGCTATTC
ACTTTGCAAAACTCCAGTCGCTTGCCTTTTTTGCAATATGCTGAAAACCGTGAGCTAAGAAAAAATATTTATGAAGCTTA
TATCAACCGGGGGAATCATGATGATGCGAATGACAATAAAGAGATATTGGGAAAGATCATGGCATTGCGTTTGGAACAGG
CAAAATTATTAGGATTCGATTGTTATTCCAATTTTGTACTGGATGAGAACATGGCTAAGAATTCGCAGACAGTCATGGAT
TTCTTGAACAACCTGTGGGGATACTCACTGGAAAATGCAAAGAAAGAGGCCGCCGAGTTGCAGAAAATAATGGATAAGGA
AGGTAAGGGAGAGAAGCTGGCTGCATGGGACTGGTGGTATTATGCCGAAAAATTGCGTCAGGAAAAGTATGATTTGAATG
AAGATGAAATCAAGCCCTATTTCAGTTTGGAAGATGTGCGTAGCGGATTGTATACCGTGGCCAACAAGCTGTATGGCATT
ACATTGACCGAACTGAATGATGTGCCCGTATATGAGCCGGATGTGAAAGTGTATGAAGTAAAGGATGCCGATGGCTCATT
TTTGGGATTGTTCTATGCGGATTACTTTCCACGCGCAGGTAAGCGTGGTGGCGCATGGATGAGTAATTTTCGTGAACAGG
CCGGTGAAGTACGTCCTTTAATTTATAATGTGGCAAGTTTTACTAAACCTGCAGGAAATATGCCTTCTTTACTGACTTTG
GATGAGGTGGAAACCATGTTTCATGAGTTTGGACATGCATTGCACGGTATGCTGACCAAGTGTAACTACAAAGGAGTGTC
CGGTACCAGTGTGGCGCAGGATTTTGTAGAACTTCCTTCACAGATTATGGAACATTGGGCTGTAGAACCTGAAGTGCTGA
AACTCTATGCCAAGCATTATGAAACAAGAGAAGTGATTCCGGATGAGCTGATTACGAAAATCCAAAATCAGGGTACTTTT
AATCAAGGTTTTATGACTACGGAATTATTGGCAGCCGCTTTGCTTGATATGGAACTGCATAACCTGACTGATACAGACAA
TCTGAATGTCGTTGCTTTTGAAAAAGAAACGATGGACAAGCTGGGGCTGATTCCTGAAATAGCTCCTCGGTATCGCGCCA
CTTATTTTAGTCATATTATAGGTGGATATGCTGCTGGGTATTACAGCTATCTATGGGCAGAAGTTCTTGACACGGATGCT
TTTGAAGCGTTTAAAGAACATGGAGTGTTCGATAAAAATACCGCAGATTCTTTCCGTAAAAATATTCTAGAGAAAGGTGG
AACGGAAGATCCTATGACCCTTTACAGAGGTTTTCGTGGGGCTGATCCCAGCTTGGAACCCTTGCTTAAAAACAGGGGTT
TGAAATAA

Upstream 100 bases:

>100_bases
ACCGTTGTACGGTGGATAATACGATAAAGAGTTCGGATCATTACCCCATTTGGTGTTATGTGGCGGAGAAGTGATTTTAC
ATACCTTTAATTGACAGATT

Downstream 100 bases:

>100_bases
AATAGACTGTGAGATAGAATAATTTAGGCTGCAAAAAATGCTTTTGCAGCCTTTTTTCTCTTTTGGAATCTAAATATTTG
TGTTTGATACCGTGGGAATG

Product: peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 695; Mature: 695

Protein sequence:

>695_residues
MKRLLFTLATCCVMCACEQKTEMNPFFTEFQTEYGAPDFTKIRLEHYEPAFLKGIEEQNAEIKAIVDNPEEPTFENTIVA
LDKSGGILARVSGVFFALTEADTNDSLTALNEKMAPVLSEHSDNIYLNQDLYKRVADVHQQEQEGKITLTTEQHRLLDKY
YKAFVRSGAGLDAGKQSRLREINKELSTLGIAFDNHILNENNAYQLVIENEADLAGLPEWVKAGAAEEAKAAGKEGKWLF
TLQNSSRLPFLQYAENRELRKNIYEAYINRGNHDDANDNKEILGKIMALRLEQAKLLGFDCYSNFVLDENMAKNSQTVMD
FLNNLWGYSLENAKKEAAELQKIMDKEGKGEKLAAWDWWYYAEKLRQEKYDLNEDEIKPYFSLEDVRSGLYTVANKLYGI
TLTELNDVPVYEPDVKVYEVKDADGSFLGLFYADYFPRAGKRGGAWMSNFREQAGEVRPLIYNVASFTKPAGNMPSLLTL
DEVETMFHEFGHALHGMLTKCNYKGVSGTSVAQDFVELPSQIMEHWAVEPEVLKLYAKHYETREVIPDELITKIQNQGTF
NQGFMTTELLAAALLDMELHNLTDTDNLNVVAFEKETMDKLGLIPEIAPRYRATYFSHIIGGYAAGYYSYLWAEVLDTDA
FEAFKEHGVFDKNTADSFRKNILEKGGTEDPMTLYRGFRGADPSLEPLLKNRGLK

Sequences:

>Translated_695_residues
MKRLLFTLATCCVMCACEQKTEMNPFFTEFQTEYGAPDFTKIRLEHYEPAFLKGIEEQNAEIKAIVDNPEEPTFENTIVA
LDKSGGILARVSGVFFALTEADTNDSLTALNEKMAPVLSEHSDNIYLNQDLYKRVADVHQQEQEGKITLTTEQHRLLDKY
YKAFVRSGAGLDAGKQSRLREINKELSTLGIAFDNHILNENNAYQLVIENEADLAGLPEWVKAGAAEEAKAAGKEGKWLF
TLQNSSRLPFLQYAENRELRKNIYEAYINRGNHDDANDNKEILGKIMALRLEQAKLLGFDCYSNFVLDENMAKNSQTVMD
FLNNLWGYSLENAKKEAAELQKIMDKEGKGEKLAAWDWWYYAEKLRQEKYDLNEDEIKPYFSLEDVRSGLYTVANKLYGI
TLTELNDVPVYEPDVKVYEVKDADGSFLGLFYADYFPRAGKRGGAWMSNFREQAGEVRPLIYNVASFTKPAGNMPSLLTL
DEVETMFHEFGHALHGMLTKCNYKGVSGTSVAQDFVELPSQIMEHWAVEPEVLKLYAKHYETREVIPDELITKIQNQGTF
NQGFMTTELLAAALLDMELHNLTDTDNLNVVAFEKETMDKLGLIPEIAPRYRATYFSHIIGGYAAGYYSYLWAEVLDTDA
FEAFKEHGVFDKNTADSFRKNILEKGGTEDPMTLYRGFRGADPSLEPLLKNRGLK
>Mature_695_residues
MKRLLFTLATCCVMCACEQKTEMNPFFTEFQTEYGAPDFTKIRLEHYEPAFLKGIEEQNAEIKAIVDNPEEPTFENTIVA
LDKSGGILARVSGVFFALTEADTNDSLTALNEKMAPVLSEHSDNIYLNQDLYKRVADVHQQEQEGKITLTTEQHRLLDKY
YKAFVRSGAGLDAGKQSRLREINKELSTLGIAFDNHILNENNAYQLVIENEADLAGLPEWVKAGAAEEAKAAGKEGKWLF
TLQNSSRLPFLQYAENRELRKNIYEAYINRGNHDDANDNKEILGKIMALRLEQAKLLGFDCYSNFVLDENMAKNSQTVMD
FLNNLWGYSLENAKKEAAELQKIMDKEGKGEKLAAWDWWYYAEKLRQEKYDLNEDEIKPYFSLEDVRSGLYTVANKLYGI
TLTELNDVPVYEPDVKVYEVKDADGSFLGLFYADYFPRAGKRGGAWMSNFREQAGEVRPLIYNVASFTKPAGNMPSLLTL
DEVETMFHEFGHALHGMLTKCNYKGVSGTSVAQDFVELPSQIMEHWAVEPEVLKLYAKHYETREVIPDELITKIQNQGTF
NQGFMTTELLAAALLDMELHNLTDTDNLNVVAFEKETMDKLGLIPEIAPRYRATYFSHIIGGYAAGYYSYLWAEVLDTDA
FEAFKEHGVFDKNTADSFRKNILEKGGTEDPMTLYRGFRGADPSLEPLLKNRGLK

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=594, Percent_Identity=33.3333333333333, Blast_Score=297, Evalue=3e-80,
Organism=Homo sapiens, GI14149738, Length=641, Percent_Identity=30.1092043681747, Blast_Score=253, Evalue=4e-67,
Organism=Homo sapiens, GI156105687, Length=680, Percent_Identity=24.7058823529412, Blast_Score=183, Evalue=6e-46,
Organism=Escherichia coli, GI1787819, Length=684, Percent_Identity=42.5438596491228, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI1789913, Length=684, Percent_Identity=37.4269005847953, Blast_Score=428, Evalue=1e-121,
Organism=Caenorhabditis elegans, GI71999758, Length=577, Percent_Identity=22.3570190641248, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32565901, Length=468, Percent_Identity=22.6495726495727, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6319793, Length=659, Percent_Identity=29.4385432473445, Blast_Score=222, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322715, Length=552, Percent_Identity=24.8188405797101, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI21356111, Length=587, Percent_Identity=25.0425894378194, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI20129717, Length=447, Percent_Identity=26.8456375838926, Blast_Score=169, Evalue=4e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 78971; Mature: 78971

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLFTLATCCVMCACEQKTEMNPFFTEFQTEYGAPDFTKIRLEHYEPAFLKGIEEQNA
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHCHHHCCC
EIKAIVDNPEEPTFENTIVALDKSGGILARVSGVFFALTEADTNDSLTALNEKMAPVLSE
EEEEEECCCCCCCCCCEEEEEECCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHC
HSDNIYLNQDLYKRVADVHQQEQEGKITLTTEQHRLLDKYYKAFVRSGAGLDAGKQSRLR
CCCCEEECHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EINKELSTLGIAFDNHILNENNAYQLVIENEADLAGLPEWVKAGAAEEAKAAGKEGKWLF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCHHHHHCCCCCCEEE
TLQNSSRLPFLQYAENRELRKNIYEAYINRGNHDDANDNKEILGKIMALRLEQAKLLGFD
EECCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHH
CYSNFVLDENMAKNSQTVMDFLNNLWGYSLENAKKEAAELQKIMDKEGKGEKLAAWDWWY
HHHCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
YAEKLRQEKYDLNEDEIKPYFSLEDVRSGLYTVANKLYGITLTELNDVPVYEPDVKVYEV
HHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEE
KDADGSFLGLFYADYFPRAGKRGGAWMSNFREQAGEVRPLIYNVASFTKPAGNMPSLLTL
ECCCCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEH
DEVETMFHEFGHALHGMLTKCNYKGVSGTSVAQDFVELPSQIMEHWAVEPEVLKLYAKHY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ETREVIPDELITKIQNQGTFNQGFMTTELLAAALLDMELHNLTDTDNLNVVAFEKETMDK
HHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHH
LGLIPEIAPRYRATYFSHIIGGYAAGYYSYLWAEVLDTDAFEAFKEHGVFDKNTADSFRK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NILEKGGTEDPMTLYRGFRGADPSLEPLLKNRGLK
HHHHCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MKRLLFTLATCCVMCACEQKTEMNPFFTEFQTEYGAPDFTKIRLEHYEPAFLKGIEEQNA
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCCCHHHHCHHHCCC
EIKAIVDNPEEPTFENTIVALDKSGGILARVSGVFFALTEADTNDSLTALNEKMAPVLSE
EEEEEECCCCCCCCCCEEEEEECCCCEEEEECCEEEEEEECCCCCCHHHHHHHHHHHHHC
HSDNIYLNQDLYKRVADVHQQEQEGKITLTTEQHRLLDKYYKAFVRSGAGLDAGKQSRLR
CCCCEEECHHHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
EINKELSTLGIAFDNHILNENNAYQLVIENEADLAGLPEWVKAGAAEEAKAAGKEGKWLF
HHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHCCCCHHHHHCCCCCCEEE
TLQNSSRLPFLQYAENRELRKNIYEAYINRGNHDDANDNKEILGKIMALRLEQAKLLGFD
EECCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHH
CYSNFVLDENMAKNSQTVMDFLNNLWGYSLENAKKEAAELQKIMDKEGKGEKLAAWDWWY
HHHCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHH
YAEKLRQEKYDLNEDEIKPYFSLEDVRSGLYTVANKLYGITLTELNDVPVYEPDVKVYEV
HHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCEEEEE
KDADGSFLGLFYADYFPRAGKRGGAWMSNFREQAGEVRPLIYNVASFTKPAGNMPSLLTL
ECCCCCEEHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEH
DEVETMFHEFGHALHGMLTKCNYKGVSGTSVAQDFVELPSQIMEHWAVEPEVLKLYAKHY
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ETREVIPDELITKIQNQGTFNQGFMTTELLAAALLDMELHNLTDTDNLNVVAFEKETMDK
HHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHHH
LGLIPEIAPRYRATYFSHIIGGYAAGYYSYLWAEVLDTDAFEAFKEHGVFDKNTADSFRK
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
NILEKGGTEDPMTLYRGFRGADPSLEPLLKNRGLK
HHHHCCCCCCHHHHHHCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]