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The map label for this gene is pdxY [H]

Identifier: 150003445

GI number: 150003445

Start: 1174439

End: 1175311

Strand: Direct

Name: pdxY [H]

Synonym: BVU_0872

Alternate gene names: 150003445

Gene position: 1174439-1175311 (Clockwise)

Preceding gene: 150003444

Following gene: 150003451

Centisome position: 22.75

GC content: 48.8

Gene sequence:

>873_bases
ATGTATACAAATAAAGTAAAGAAGATAGCTGCGGTACACGATCTGTCCGGTGCAGGGCGCGTATCCCTCACCGTCGTTAT
CCCTATCCTCTCATCCATGGGCTTTCAAGTCTGCCCTCTGCCCACAGCCGTATTATCCAGCCACACCCAATACCCGCACT
TCTCTTTCTTGGACCTCACGGACGAGATGCCCAAGATTATCAGTGAATGGAAACAACTTGGCGTACAATTCGATGCTATT
TATACGGGCTACTTGGGATCTCCCCGCCAGATACAAATCGTATCCGGGTTCATTGATGATTTCCGCCAGTCCGACAGCCT
GGTCATGATAGATCCCGTATTAGGAGACAACGGAAAGCTATATACCAACTTTGACGAACAAATGATTCTGGAAATGCGTC
ACCTCATCCGGAAAGCAGATGTCATCACGCCCAATATGACCGAACTGTTCTATTTGCTGGACAAACCCTATAAAGCGGAG
AATACAGACGAAGAACTAAAAGCTTACCTGCATGAAATTTCGGAGCACGGCCCCGGTATCGTTATTATCACCAGCGTGCC
CGTACAGGGAGATCCTCGCAAAACTTCCGTTTACGCCTATGACAGACAGGGAAACCGCTATTGGAAAGTAACGTGTCCCT
ACCTGCCCGCACACTATCCCGGCACAGGCGATACATTTACCAGTGTGATAACCGGCTCACTGATACAAGGCGACAGTCTT
CCTATCGCCTTGGACCGCGCCACACAGTTTATCCTTCAAGGCATCCGCGCCACTTTCGGCTATGAATATGATAATCGGGA
AGGCATTTTGCTGGAGAAGGTGCTGCATAATCTGGATATGCCTATTCAGGTGAGCAGCTACGAATTGATTTGA

Upstream 100 bases:

>100_bases
TGGGCCGGCAAGACATAAAGGTAAAAAGCATAGCATTGGAATAACTTTCTTCCGGTTTACCTGTTATATATACCATCCAT
AACGCTTAATTCATGAAGAT

Downstream 100 bases:

>100_bases
GGACCCTGAAAGTAGAAGATCTGAAACGCCCTGGAAAGAAGCTTGTACCAAGCCCTATTGCTCCGACGATTAAGGTCGTT
TTTCCTTATAGCTAACCCTT

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MYTNKVKKIAAVHDLSGAGRVSLTVVIPILSSMGFQVCPLPTAVLSSHTQYPHFSFLDLTDEMPKIISEWKQLGVQFDAI
YTGYLGSPRQIQIVSGFIDDFRQSDSLVMIDPVLGDNGKLYTNFDEQMILEMRHLIRKADVITPNMTELFYLLDKPYKAE
NTDEELKAYLHEISEHGPGIVIITSVPVQGDPRKTSVYAYDRQGNRYWKVTCPYLPAHYPGTGDTFTSVITGSLIQGDSL
PIALDRATQFILQGIRATFGYEYDNREGILLEKVLHNLDMPIQVSSYELI

Sequences:

>Translated_290_residues
MYTNKVKKIAAVHDLSGAGRVSLTVVIPILSSMGFQVCPLPTAVLSSHTQYPHFSFLDLTDEMPKIISEWKQLGVQFDAI
YTGYLGSPRQIQIVSGFIDDFRQSDSLVMIDPVLGDNGKLYTNFDEQMILEMRHLIRKADVITPNMTELFYLLDKPYKAE
NTDEELKAYLHEISEHGPGIVIITSVPVQGDPRKTSVYAYDRQGNRYWKVTCPYLPAHYPGTGDTFTSVITGSLIQGDSL
PIALDRATQFILQGIRATFGYEYDNREGILLEKVLHNLDMPIQVSSYELI
>Mature_290_residues
MYTNKVKKIAAVHDLSGAGRVSLTVVIPILSSMGFQVCPLPTAVLSSHTQYPHFSFLDLTDEMPKIISEWKQLGVQFDAI
YTGYLGSPRQIQIVSGFIDDFRQSDSLVMIDPVLGDNGKLYTNFDEQMILEMRHLIRKADVITPNMTELFYLLDKPYKAE
NTDEELKAYLHEISEHGPGIVIITSVPVQGDPRKTSVYAYDRQGNRYWKVTCPYLPAHYPGTGDTFTSVITGSLIQGDSL
PIALDRATQFILQGIRATFGYEYDNREGILLEKVLHNLDMPIQVSSYELI

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788758, Length=263, Percent_Identity=26.2357414448669, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787924, Length=237, Percent_Identity=26.1603375527426, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507759, Length=235, Percent_Identity=30.2127659574468, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17507757, Length=245, Percent_Identity=29.3877551020408, Blast_Score=78, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324354, Length=232, Percent_Identity=25.8620689655172, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320806, Length=212, Percent_Identity=25, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45553007, Length=232, Percent_Identity=28.8793103448276, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 32646; Mature: 32646

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTNKVKKIAAVHDLSGAGRVSLTVVIPILSSMGFQVCPLPTAVLSSHTQYPHFSFLDLT
CCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHHCCCEECCCCHHHHHCCCCCCCEEEECCC
DEMPKIISEWKQLGVQFDAIYTGYLGSPRQIQIVSGFIDDFRQSDSLVMIDPVLGDNGKL
HHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEHHHHHHHHHCCCCEEEEEEEECCCCCE
YTNFDEQMILEMRHLIRKADVITPNMTELFYLLDKPYKAENTDEELKAYLHEISEHGPGI
EECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCE
VIITSVPVQGDPRKTSVYAYDRQGNRYWKVTCPYLPAHYPGTGDTFTSVITGSLIQGDSL
EEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PIALDRATQFILQGIRATFGYEYDNREGILLEKVLHNLDMPIQVSSYELI
CEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEECCEECC
>Mature Secondary Structure
MYTNKVKKIAAVHDLSGAGRVSLTVVIPILSSMGFQVCPLPTAVLSSHTQYPHFSFLDLT
CCCHHHHHHHHHHCCCCCCEEEEEEEEEHHHHCCCEECCCCHHHHHCCCCCCCEEEECCC
DEMPKIISEWKQLGVQFDAIYTGYLGSPRQIQIVSGFIDDFRQSDSLVMIDPVLGDNGKL
HHHHHHHHHHHHHCEEEEEEEECCCCCCCEEEEHHHHHHHHHCCCCEEEEEEEECCCCCE
YTNFDEQMILEMRHLIRKADVITPNMTELFYLLDKPYKAENTDEELKAYLHEISEHGPGI
EECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCE
VIITSVPVQGDPRKTSVYAYDRQGNRYWKVTCPYLPAHYPGTGDTFTSVITGSLIQGDSL
EEEEECCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCC
PIALDRATQFILQGIRATFGYEYDNREGILLEKVLHNLDMPIQVSSYELI
CEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]